Clinical trials: Cochlear Synaptopathy
Hearing Loss, Sensorineural, Cochlear Synaptopathy
Evaluation of the CochSyn Test Prototype to Measure Cochlear Synaptopathy
This study investigates a newly developed test, The CochSyn test that can quantify cochlear synaptopathy (CS) (a new type of sensorineural hearing loss (SNHL)) earlier than the current golden standard pure-tone audiogram.This…
- Conditions
- Hearing Loss, Sensorineural, Cochlear Synaptopathy, Cochlear Hearing Loss
- Trial name
- EarDiTech (NCT06114680)
- Testing
- CochSyn test prototype, Universal Smart Box (USB)
- Where
- Belgium
- Volunteers
- 179 people, healthy volunteers welcome
- Sponsor
- University Ghent
Hearing Loss, Sensorineural, Cochlear Hearing Loss
Evaluation of the CochSyn Device in Clinical Practice
This study investigates a new type of auditory evoked brain potentials for the quantification and classification of peripheral hearing damage (The CochSyn Test).
- Conditions
- Hearing Loss, Sensorineural, Cochlear Hearing Loss, Cochlear Synaptopathy, DFNA9
- Trial name
- Earditech 2 (NCT07091071)
- Testing
- CochSyn device
- Where
- 3 sites in Belgium
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- University Ghent
Sensorineural Hearing Loss
Phase I/IIa Study Evaluating Safety and Efficacy of an Intratympanic Dose of PIPE-505 in Subjects With Hearing Loss
This is a randomized, double-blind study of PIPE-505, or placebo, in subjects with hearing loss associated with speech-in-noise impairment.
- Trial name
- NCT04462198
- Testing
- PIPE-505
- Where
- 8 sites in United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Contineum Therapeutics
Hidden Hearing Loss, Cochlear Synaptopathy
Relationship Between LS Chirp ABR and Speech-in-Noise Skills in Hidden Hearing Loss
It is known that the underlying problem in Hidden Hearing Loss (HHL) is cochlear synaptopathy (CS) and that low-spontaneous-rate auditory nerve fibers play an important role in this pathology.
- Trial name
- NCT07230236
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Seneorineural Deafness, Sudden Sensorineural Hearing Loss
A Phase 1b/2a, Study Evaluating the Safety, PK/PD and Efficacy of NS101 in Healthy Volunteers and SSNHL Patients
The goal of this 2 step-up, exploratory study is to test safey, tolerability and PK/PD profiles in healthy volunteers and safety, tolerability and efficacy in sudden sensorineural hearing loss patients as an early salvage…
- Trial name
- NCT06249919
- Testing
- NS101
- Where
- 16 sites in South Korea
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Neuracle Science Co., LTD.