Clinical trials: Coeliac Disease
Ataxia
Autoimmunity in Neurologic Complications of Celiac Disease
This study, done in collaboration with Cornell University in New York, will explore the potential role of the body s immune response to gluten in ataxia.
- Trial name
- NCT00692861
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Celiac Disease
Pancreatic Enzyme Supplementation for Celiac Disease
The purpose of this protocol is to conduct a pilot study to investigate whether pancreatic enzyme supplementation will improve symptoms in individuals with celiac disease who suffer persistent symptoms despite a gluten free diet.
- Trial name
- NCT02475369
- Testing
- pancrelipase
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Beth Israel Deaconess Medical Center
Mesenteric Ischemia, Median Arcuate Ligament Syndrome
Coeliac Artery Release or Sham Operation
In patients with Median Arcuate Ligament Syndrome (MALS), significant external compression of the coeliac artery (CA) by the median arcuate ligament (MAL) increasing mucosal ischemia (1,2) is assumed to cause chronic disabling…
- Conditions
- Mesenteric Ischemia, Median Arcuate Ligament Syndrome, Dunbar Syndrome, Coeliac Artery Compression
- Trial name
- CARoSO (NCT05468580)
- Testing
- Endoscopic Coeliac Artery Release (eCAR)
- Where
- Netherlands
- Volunteers
- 70 people
- Sponsor
- Medisch Spectrum Twente
Celiac Disease
Glutenfree, Gut Microbiota and Metabolic Regulation
High intake of dietary fiber provides health benefits and reduces the risk of developing cardio-metabolic diseases, such as type 2 diabetes (T2D) and cardiovascular disease (CVD).
- Trial name
- GRAIN (NCT05135923)
- Testing
- Randomized, controlled trial (RCT) with parallel arms and double blinded
- Where
- Norway
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Oslo Metropolitan University
Celiac Disease
Impact of Gluten Contamination in Celiac Patients Clinically Responsive and Unresponsive to the Gluten-free Diet
The primary aim of the study is to detect the presence of gluten immunogenic peptides (GIP) in urine samples from celiac patients on a gluten-free diet clinically responsive and non-responsive to dietary treatment and from…
- Trial name
- GIP (NCT05066191)
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Celiac Disease in Children, Nutritional Assessment
Assessment of Nutritional Status in Celiac Disease Using Muscle Ultrasound in Pediatric Patients.
The aim is to explain that celiac disease (CD) is an autoimmune, familial disease that develops in genetically predisposed individuals as a result of sensitivity to gluten found in grains and grain products, causing…
- Trial name
- NCT07885735
- Testing
- performing muscle ultrasonography on patients
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
IBS in Celiac Desease
Probiotics for the Treatment of Irritable Bowel Syndrome in Celiac Patients
Probiotics play an important role in preventing overgrowth of potentially pathogenic bacteria and maintaining the integrity of the gut mucosal barrier.
- Trial name
- ProCel (NCT01699191)
- Testing
- Probiotic
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- University of Bari
Celiac Disease
Risk of Celiac Disease and Age at Gluten Introduction
The purpose of this study is to determine whether age at introduction of gluten-containing cereals (e.g. wheat) plays a role in influencing the risk of celiac disease (CD) development in infants with a first-degree relative…
- Trial name
- CELIPREV (NCT00639444)
- Testing
- gluten-free, normocaloric diet from 6 to 12 months
- Where
- Italy
- Volunteers
- 703 people
- Sponsor
- Università Politecnica delle Marche
Celiac Disease
Evaluating the Efficacy and Tolerability of ZED1227 in Subjects With Non-responsive Celiac Disease
A study to discover if ZED1227 can improve continued celiac disease symptoms despite a gluten-free diet
- Trial name
- CEC-013/CEL (NCT07298343)
- Testing
- ZED1227 + SIGE
- Where
- Germany
- Volunteers
- 356 people
- Sponsor
- Dr. Falk Pharma GmbH
Colorectal Cancer, Small Intestinal Bacterial Overgrowth Syndrome (SIBO)
Urine Metabolites in the Diagnosis of Disease
The goal of this observational study is to validate a non-invasive, urine-based diagnostic technology for the detection and differentiation of various gastrointestinal (GI) diseases.
- Conditions
- Colorectal Cancer, Small Intestinal Bacterial Overgrowth Syndrome (SIBO), Crohn Disease, Celiac Disease
- Trial name
- NCT06710067
- Where
- 4 sites in United States
- Volunteers
- 1,250 people, healthy volunteers welcome
- Sponsor
- Luventix, Inc.
Celiac Disease
Gluten Technology and Education for Celiac Health
The investigators propose to plan for a multi-center randomized controlled trial (M-RCT) to test the effectiveness of novel gluten detection technologies as an adjunct to telemedicine to manage celiac disease in newly diagnosed…
- Trial name
- GLUTECH (NCT06059716)
- Testing
- Gluten detection technology, Continuous telemedicine monitoring
- Where
- 4 sites in United States
- Volunteers
- 200 people
- Sponsor
- Columbia University
Celiac Disease in Children, Non-Alcoholic Fatty Liver Disease
Liver Steatosis in Pediatric CD Patients
Celiac disease (CD) is an autoimmune enteropathy triggered by the intake of gluten, characterized by a genetic predisposition. Although, CD is often associated with malabsorption symptoms, a growing number of affected subjects…
- Trial name
- NCT06206616
- Testing
- Gluten-free diet
- Where
- 2 sites in Italy
- Volunteers
- 91 people
- Sponsor
- University of Palermo
Celiac Disease in Children
Virtual Reality to Teach, Improve Outcomes, and Engage (VIRTUE): Virtual Reality to Improve Gluten-Free Diet Knowledge in Pediatric Celiac Disease
1. Specific Aim (1) is to assess both the immediate and longer term impact of VIRTUE on the patient's GFD knowledge compared to standard of care (SOC) dietary education. 2.
- Trial name
- VIRTUE (NCT04440501)
- Testing
- Virtual Reality Goggles to provide education a regarding the gluten free diet.
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Stanford University
Celiac Disease
Effectiveness of PENTABIOCEL in Clinical and Laboratory Recovery of Children With Celiac Disease
Celiac disease (CD) is an inflammatory condition of the small intestine. Environmental and genetic factors are involved in the development of CD.
- Trial name
- NCT03857360
- Testing
- Pentabiocel
- Where
- Italy
- Volunteers
- 85 people
- Sponsor
- Università Politecnica delle Marche
Celiac Disease in Children, Nutrition Disorder, Child
GF-NOURISH (Gluten Free Nutrition Optimization Through Ultra-processed Food Reduction and Improved Strategies for Health)
The investigators propose the Gluten Free Nutrition Optimization through Ultra-processed food Reduction and Improved Strategies for Health (GF-NOURISH) study to demonstrate the feasibility and success of a nutritional education…
- Trial name
- GF-NOURISH (NCT06356220)
- Testing
- Gluten-Free Diet Education
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Boston Children's Hospital
Celiac Disease
Choosing a Preferred Serology Kit for Screening and Diagnosis of Celiac Disease
The investigators will perform prospective observational multicenter study which includes children with suspicion of CD who referred to gastroscopy and intestinal biopsies (study group) and children without suspicion of CD who…
- Trial name
- NCT02805816
- Where
- Israel
- Volunteers
- 128 people
- Sponsor
- Rabin Medical Center
Celiac Disease, Non-celiac Gluten Sensitivity
Lymphocytic Enteritis and Suspected Coeliac Disease: Gluten vs Placebo
Patients with lymphocytic enteritis (LE), HLA-DQ2/8+, negative celiac serology and clinical and histological response to a gluten-free diet (GFD) do not fulfil the diagnostic criteria of coeliac disease (CoD).
- Trial name
- NCT02472704
- Testing
- Gluten challenge
- Volunteers
- 18 people
- Sponsor
- Hospital Mutua de Terrassa
Digestive System Disease
A Study of PVP001, PVP002, and PVP003 in Healthy Adults and PVP001 and PVP002 in Adults With Celiac Disease
It is hoped that different forms of the same medicine, called PVP001, PVP002, and PVP003, will help people with celiac disease. Both healthy adults and adults with celiac disease will take part in this study.
- Trial name
- NCT03701555
- Testing
- PvP001 100 mg, PvP001 300 mg, PvP001 900 mg
- Where
- United States
- Volunteers
- 139 people, healthy volunteers welcome
- Sponsor
- Millennium Pharmaceuticals, Inc.
Celiac Disease
Oral AGY for Celiac Disease
Celiac disease (CD) is an autoimmune disease of the small intestine caused by the consumption of gluten proteins from widely used food sources such as wheat, rye, and barley.
- Trial name
- NCT01765647
- Testing
- AGY
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- Igy Inc.
Type 1 Diabetes, Autoimmune Diseases
Additional Autoimmune Diseases With Type 1 Diabetes in Pediatrics at Diabetes Diagnosis and During Follow-up
This study aims to describe the prevalence of additional autoimmune diseases and their specific antibodies at type 1 diabetes (T1D) diagnosis, and their incidence rate during follow-up, for children and adolescents.
- Conditions
- Type 1 Diabetes, Autoimmune Diseases, Hashimoto Disease, Graves Disease
- Trial name
- AADT1D (NCT04789993)
- Testing
- No intervention.
- Where
- France
- Volunteers
- 250 people
- Sponsor
- Central Hospital, Nancy, France