Clinical trials: Coeliac Disease
Celiac Disease
Prevalence of Renal Disease in Children With Celiac Disease
To assess the prevalence of renal disease in a pediatric population of patients with celiac disease by looking for the presence of hematuria and/or proteinuria.
- Trial name
- COELIGAN (NCT05049876)
- Testing
- urine sample taken during consultations
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Celiac Disease in Children, Nutrition, Healthy
Safe and Secure Gluten Free Diet
The only treatment for celiac disease (CD) consists of following a strict lifelong gluten-free diet, which may lead to potential dietary imbalances and associated diseases.
- Conditions
- Celiac Disease in Children, Nutrition, Healthy, Quality of Life
- Trial name
- NCT07436884
- Testing
- Dietary assesment for children with celiac disease
- Where
- Spain
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- University of the Basque Country (UPV/EHU)
Pancreatic Carcinoma Metastatic, Pancreatic Adenocarcinoma
Trial Comparing EUS-guided Radiofrequency Ablation vs. EUS-guided Celiac Plexus Neurolysis
Pancreatic cancer is the second most common gastrointestinal malignancy. Abdominal discomfort is a main symptom in patients with pancreatic cancer. Approximately 75% have pain at diagnosis and over 90% in advanced stages.
- Conditions
- Pancreatic Carcinoma Metastatic, Pancreatic Adenocarcinoma, Pancreatic Neoplasms, Pancreatic Cancer
- Trial name
- NCT03152487
- Testing
- Celiac Plexus Neurolysis, Radiofrequency Ablation
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- AdventHealth
Pain, Pancreatic Cancer
Endoscopic Ultrasound (EUS) Guided-Celiac Plexus Neurolysis (CPN) in Unresectable Pancreatic Cancer
The purpose of this study is to examine endoscopic ultrasound guided celiac plexus neurolysis (CPN) with analgesic therapy in patients with unresectable pancreatic cancer as it applies to decreasing the severity of abdominal pain…
- Trial name
- NCT00968175
- Testing
- Ultrasound guided celiac plexus neurolysis (CPN)
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- University of Alabama at Birmingham
Celiac Disease in Children, Celiac Disease
Development of CELIAC-Q KIDS: A Patient-Reported Outcome Measure for Pediatric Celiac Disease
A multicentre, prospective observational study to develop the CELIAC-Q KIDS patient reported outcome measure for children and adolescents with celiac disease.
- Conditions
- Celiac Disease in Children, Celiac Disease, Patient-reported Outcome Measures
- Trial name
- NCT05548166
- Testing
- Interview and scale development
- Where
- 2 sites in Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- McMaster University
Gluten Sensitivity, Celiac Disease
Gluten Free Diet in People With Schizophrenia: A Pilot Study
Background: Celiac disease is an immune-mediated reaction to gluten, presenting with diarrhea, weight loss, abdominal complaints and a range of less common associated neurologic and psychiatric symptoms.
- Trial name
- NCT01558557
- Testing
- Gluten Free Diet
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- University of Maryland, Baltimore
Autoimmune Diseases, Ulcerative Colitis
A Biospecimen Collection Study to Identify the Targets of Disease-Reactive T Cells in Patients With Autoimmune Disease
The most clinically meaningful way to discover new targets of T cells in autoimmune diseases is to study the tissues of patients with active autoimmune disease mediated organ inflammation.
- Conditions
- Autoimmune Diseases, Ulcerative Colitis, Multiple Sclerosis, Scleroderma
- Trial name
- NCT06587828
- Testing
- Companion blood samples with procedure
- Where
- 11 sites in United States
- Volunteers
- 238 people
- Sponsor
- TScan Therapeutics, Inc.
Celiac Disease in Children, Celiac Disease in Adolescents
Effect of Adherence to a Gluten-Free Diet on Cognitive and Motor Dual-Task Performance in Adolescents Diagnosed With Celiac Disease
The aim of this cross-sectional observational study is to comprehensively examine the effects of adherence to a gluten-free diet on cognitive, motor, and psychosocial functions in adolescents aged 8-18 years diagnosed with celiac…
- Trial name
- NCT07382999
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Inonu University
Irritable Bowel Syndrome, Crohn Disease
Evaluation of the SIMBA Capsule for Small Intestinal Dysbiosis
The SIMBA Capsule is a small, single-use, ingestible capsule that allows for the non-invasive sampling of small bowel contents using purely mechanical means.
- Conditions
- Irritable Bowel Syndrome, Crohn Disease, Celiac Disease, Ulcerative Colitis
- Trial name
- NCT05633706
- Testing
- fluid biopsy capsule
- Where
- Canada
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Nimble Science Ltd.
Fibromyalgia
Efficacy of a Gluten-free Diet for the Treatment of Fibromyalgia
Fibromyalgia patients frequently suffer from symptoms similar to those of adult celiac disease, raising the possibility that some fibromyalgia patients experience oligosymptomatic celiac disease or non-celiac gluten intolerance.
- Trial name
- NCT01881360
- Testing
- Gluten-free diet, Hypocaloric diet
- Where
- Spain
- Volunteers
- 81 people
- Sponsor
- Universidad de Granada
Food Intolerance, Celiac Disease
"Gluten Friendly" Treatment in Celiac Disease
A PROSPECTIVE, double blind, placebo-controlled trial
- Trial name
- GLUFR (NCT03137862)
- Testing
- Gluten free bread, Gluten friendly bread 3g/day, Gluten friendly bread 6g/day
- Where
- Italy
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Casa Sollievo della Sofferenza IRCCS
Celiac Disease, Villous Atrophy of Intestine
Persistent Villous Atrophy in Celiac Disease Patients Following an Intentionally Strict Gluten-free Diet
Celiac disease (CD) is an immune-mediated disease characterized by small intestinal inflammation from gluten ingestion, a group of proteins present in various cereals, including wheat, rye, barley, spelt, and kamut.
- Trial name
- CADER2 (NCT06500754)
- Testing
- Ultra-strict gluten-free diet
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- Hospital Mutua de Terrassa
Celiac Disease
Protocol for Correlating Enteropathic Severity and Small Intestinal CYP3A4 Activity in Patients With Celiac Disease
The small bowel biopsy is the cornerstone of for the diagnosis of celiac disease. In addition to being the gold standard for the initial diagnosis of celiac disease, periodic biopsies are also recommended on an ongoing basis for…
- Trial name
- Cyp (NCT01338324)
- Testing
- Simvastatin
- Where
- India
- Volunteers
- 41 people
- Sponsor
- All India Institute of Medical Sciences
Chronic Pancreatitis
A Pilot Study in Endoscopic Therapy on Quality of Life and Pain in Chronic Pancreatitis
This study is a prospective study designed to assess the effect of pancreatic endotherapy on quality of life, pain levels, pancreatic exocrine function, and endocrine function.
- Trial name
- EQuiPP (NCT05012150)
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Ohio State University
Type1diabetes, Celiac Disease
Newborn Screening for Genetic Susceptibility to Type 1 Diabetes and Celiac Disease and Prospective Follow-up Study
This is an observational study, in which newborn infants from the general population are screened at birth for HLA-conferred susceptibility to type 1 diabetes and celiac disease.
- Trial name
- BABYSCREEN (NCT04958356)
- Where
- Finland
- Volunteers
- 9,690 people, healthy volunteers welcome
- Sponsor
- University of Helsinki
Celiac Disease, Celiac
A Study of the Safety, Efficacy and Tolerability of Nexvax-2 in Patients With Celiac Disease (CeD)
A randomized, double-blind, placebo-controlled clinical study in human leukocyte antigen (HLA)-DQ 2.5+ adults with celiac disease (CeD).
- Conditions
- Celiac Disease, Celiac, Intestinal Disease, Malabsorption Syndromes
- Trial name
- NCT03644069
- Testing
- Nexvax2
- Where
- 41 sites in United States, Australia and 1 more
- Volunteers
- 146 people
- Sponsor
- ImmusanT, Inc.
Celiac Disease
Can a Very High Result From a Screening Test for Celiac Disease be Used to Diagnose Celiac Disease?
This study is to see if a high response to the TTG screening test for celiac disease is as accurate as the current method of diagnosing celiac disease which entails a general anesthetic and upper endoscopy to obtain biopsies of…
- Trial name
- NCT00175760
- Testing
- Diagnosis of Celiac Disease
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- University of British Columbia
Celiac Disease
A Decentralized Home-Based Study To Investigate Novel Objective Biomarker Of Gluten-Mediated Symptoms In Celiac Disease Participants (CeDar ROSE Study)
This is a decentralized study to primarily explore a novel objective digital biomarker (i.e., Gluten Dependency Index) for celiac disease-related responses triggered by gluten exposure using a wearable biosensor.
- Trial name
- NCT05686369
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Chugai Pharmaceutical
Capsule Endoscopy, Inflammatory Bowel Diseases
Differences in Preparation for Small Bowel Capsule Endoscopy
The introduction of video capsule endoscopy in 2000 has provided a convenient and minimally invasive imaging method for the whole small bowel.
- Conditions
- Capsule Endoscopy, Inflammatory Bowel Diseases, Celiac Disease
- Trial name
- NCT03351972
- Testing
- Klean Prep, Clear liquids only
- Where
- 2 sites in Canada, United Kingdom
- Volunteers
- 230 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Celiac Disease
Celiac Disease: Nutrition Education in Primary School
Celiac disease is a chronic immune-based intestinal pathology. Its prevalence is 1% and its incidence has increased in recent years.
- Trial name
- ZELIAKIDE (NCT05467865)
- Testing
- ZELIAKIDE
- Where
- Spain
- Volunteers
- 299 people, healthy volunteers welcome
- Sponsor
- University of the Basque Country (UPV/EHU)