Clinical trials: Coffee
Atherosclerosis, Cardiovascular Diseases
Coffee Consumption and Coronary Artery Calcium Score
Coffee is one of the dietary factors associated with cardiovascular disease (CVD) but its role in the cardiovascular system is not yet clear.
- Trial name
- NCT03139071
- Where
- Brazil
- Volunteers
- 4,426 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Obesity, Abdominal
Does the Bioactive Substance in Coffee, Cafestol, Have Preventive Properties on Type-2-diabetes? (Acute Substudy)
Acute, double-blinded, randomized, cross-over cafestol intervention study with fifteen participants with a large waist circumference participating in three OGTTs.
- Trial name
- NCT04911582
- Testing
- Cafestol 12 mg, Cafestol 6 mg
- Where
- Denmark
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Bioavailability, Cardiovascular Health Status
Absorption of Phenolic Acids From Coffee in Humans
Phenolic acids are naturally-occurring constituents of plant-derived foods and beverages and are characterised by a phenol ring in their structure.
- Trial name
- NCT01912144
- Testing
- Coffee
- Where
- United Kingdom
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Postoperative Ileus
Coffee Consumption for Intestinal Function Recovery After Laparoscopic Gynecologic Surgery
Minimally invasive surgery (MIS) has revolutionized women's healthcare. Laparoscopy is an excellent route of MIS. Today, laparoscopic surgery is one of the major procedure in the management of a gynecologic disease.
- Trial name
- NCT03963180
- Testing
- coffee
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Erzincan Military Hospital
Healthy
Dose Response Bioavailability of Coffee and Green Tea Antioxidants in Humans
Coffee and green tea are 2 widely consumed beverages. Both contain polyphenol antioxidant compounds (chlorogenic acids for coffee and catechins for tea).
- Trial name
- NCT01089920
- Testing
- Green tea, Coffee
- Where
- Switzerland
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Operation, Cesarean Section
Effect of Coffee Consumption on Pain and Intestinal Motility After Caesarean Section:
Objective The aim of this study was to investigate whether postoperative coffee intake affects pain levels and bowel motility in women undergoing cesarean delivery.
- Trial name
- NCT06359223
- Testing
- coffee consumption, control group
- Where
- Turkey (Türkiye)
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Diabetes Mellitus
Effect of Coffee Consumption on the Glycemic Index of Khalas Dates Tested in Healthy and Diabetic Subjects
The aim of this study was to evaluate the composition of Khalas, a very common type of dates used in the UAE and to determine the effects of drinking Arabic coffee on the results of GI tests in both healthy and diabetic subjects.
- Trial name
- NCT01422668
- Testing
- Khalas dates
- Where
- United Arab Emirates
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- United Arab Emirates University
Health Status
Effect of Date Seeds Coffee on Mood and Cognitive Performance
Limited utilizations of date seeds have previously been explored, and so previously wastage has often been the normality. However, research now indicates that several fruit seeds contain higher concentrations of beneficial total…
- Trial name
- NCT04009564
- Testing
- Date coffee, Normal coffee
- Where
- United Kingdom
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Newcastle University
Obesity
Study of Coffee Mannooligosaccharides for Weight Management
The goal of this study is to establish the role of coffee mannooligosaccharides (MOS), provided in a beverage format, on body weight regulation.
- Trial name
- MOS (NCT00932750)
- Testing
- Coffee mannooligosaccharide, Coffee mannooligosaccharides
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Mondelēz International, Inc.
Peri-Implant Health, Peri-Implantitis and Peri-implant Mucositis
Association of Coffee Consumption With Peri-Implant Status
A total of 123 participants (291 implants) applying to Bolu Abant İzzet Baysal University will be included in the study. Based on anamnesis, radiographic examination, and the 2018 classification of periodontal diseases, the…
- Trial name
- ACCPS (NCT07747558)
- Testing
- Coffee
- Where
- Turkey (Türkiye)
- Volunteers
- 291 people, healthy volunteers welcome
- Sponsor
- Tuğba ŞAHİN
At Home Setting, Coffee With or Without Caffeine
Do It Yourself (DIY) Coffee Study; Test Effect of Coffee on Cognition in an at Home Setting
Subjects will perform experiments in an at home-setting. The effect of caffeine in coffee will be tested in subjects with computer tests on attention and alertness.
- Trial name
- NCT02061982
- Testing
- Coffee consumption
- Where
- Netherlands
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- TNO
Diet Modification, Cardiovascular Risk Factor
Bioavailability and Beneficial Properties of Coffee and Cocoa Bioactive Compounds
The aim of this study will be to define the bioavailability and the beneficial properties of coffee bioactive compounds. Moreover, the contribution of cocoa-based products containing coffee to the pool of circulating metabolites…
- Conditions
- Diet Modification, Cardiovascular Risk Factor, Nutritional and Metabolic Diseases
- Trial name
- P4L (NCT03166540)
- Testing
- cup of espresso coffee, cocoa-based products containing coffee
- Where
- Italy
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Parma
CYP1A2 Polymorphism
Personalized Nutrition Caffeine Intake in Healthy Adults.
Personalized nutrition is one of the most up to date trends in human nutrition and gains much interest of general public and scientists as well.
- Trial name
- NCT04122053
- Testing
- Intervention group with genotype information, Control group without genotype information
- Where
- Poland
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Poznan University of Life Sciences
Immune Senescence, Low-grade Inflammation
Immune Benefits of Coffee
This study will assess whether coffee consumption: increases immune responses decreases inflammatory status
- Trial name
- NCT00860197
- Testing
- Fully torrefied coffee, Partially torrefied coffee
- Where
- Chile
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- University of Chile
Hypotension After Spinal Anesthesia, Post-Dural Puncture Headache
Effects of Preoperative Coffee Consumption in Cesarean Sections Under Spinal Anesthesia
The prospective study is planned in a university hospital. Spinal anesthesia is widely used for cesarean section currently for its safety, low cost, reliability, easiness to administer, immediate effect, and well-operating…
- Trial name
- NCT05262933
- Testing
- coffee, Water
- Where
- Turkey (Türkiye)
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Nutrition, Healthy
Effect of Green Coffee Extract Combined With Alpha-Lipoic Acid on Blood Glucose Homeostasis in Healthy Adults
Green coffee extract (GCE) supplementation has been shown to induce favourable health benefits on glucose metabolism and weight management.
- Trial name
- GCE (NCT06121713)
- Testing
- GCE + Low ALA, GCE + High ALA
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Balanced, Postural; Defect
The Effect of Coffee Consumption on Balance
This study aims to investigate the effects of daily coffee consumption on balance performance in healthy university students. Caffeine is a widely consumed psychoactive substance that may influence neuromuscular control, reaction…
- Conditions
- Balanced, Postural; Defect, Coffee Consumption
- Trial name
- NCT07540559
- Testing
- Daily coffee consumption (self-reported exposure)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Healthy
Influence of Coffee Consumption on BIA-derived Body Composition Parameters
Body composition analysis is frequently used in both clinical and research settings for evaluation of nutritional status and follow-up.
- Trial name
- NCT03745508
- Testing
- Instant Coffee
- Where
- Canada
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Memory Deficits
Neurophysiological Effects of Whole Coffee Cherry Extract in Older Adults
This study was designed to characterize the changes in the brain and body associated with whole coffee cherry extract (WCCE). WCCE is a patented extract of whole coffee fruit (coffee berries) from coffea arabica.
- Trial name
- NCT03812744
- Testing
- Whole coffee cherry extract (WCCE)
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Auburn University
Oral Glucose Tolerance
Coffee Roasting and Glucose Tolerance
Chlorogenic acid (CGA) in coffee may lower the postprandial glucose response. CGA is destroyed by dark roasting. In a controlled crossover trial, 11 healthy fasted volunteers consumed 300 mL of either light (LIR) or dark (DAR)…
- Trial name
- NCT02417519
- Testing
- DAR, LIR, CTR
- Where
- Denmark
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen