Clinical trials: Cognition - Other
Bipolar Disorder, Depression
Effect of Immersive Virtual Reality-based Cognitive Remediation in Patients With Mood - or Psychosis Spectrum Disorders
The goal of this clinical trial is to investigate the effect of a four-weeks, intensive virtual reality (VR)-based cognitive remediation (training) programme involving simulated daily-life challenges on cognition and functional…
- Conditions
- Bipolar Disorder, Depression, Psychotic Disorders, Cognitive Impairment
- Trial name
- NCT06038955
- Testing
- Virtual reality Based Cognitive Remediation, Virtual reality control training
- Where
- Denmark
- Volunteers
- 62 people
- Sponsor
- Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital
Schizophrenia
A Study to Evaluate the Effects of Once Daily Doses of AQW051 on Cognition, in Stable Schizophrenia Patients
This is a study in chronic stable Schizophrenia with the purpose to answer the question of whether agonism of the nicotinic alpha7 receptor is capable of enhancing cognition in a well defined chronic stable patient population…
- Trial name
- NCT01730768
- Testing
- AQW051
- Where
- 13 sites in United States
- Volunteers
- 147 people
- Sponsor
- Novartis Pharmaceuticals
Psychotic Disorders
Improving Cognitive Function of Aripiprazole in Treating Adolescents and Young Adults With Psychotic Disorder
This is a 24-week, observational, prospective study to evaluate the effectiveness of improving cognitive function of aripiprazole in treating adolescents and young adults with psychotic disorder in Taiwan.
- Trial name
- NCT00541502
- Sponsor
- Genovate Biotechnology Co., Ltd.,
Mental Health Issue, Anxiety Disorders
Arts-based Social Prescribing for Mental Health
This is a parallel-group randomised-controlled trial aiming to assess the effect of exposure to the arts on mental health and wellbeing of community dwelling recipients of mental health care.
- Conditions
- Mental Health Issue, Anxiety Disorders, Affective Disorders, Affective Disorders, Psychotic
- Trial name
- AoP-II (NCT07137572)
- Testing
- Art Prescription
- Where
- Greece
- Volunteers
- 541 people
- Sponsor
- KAVADIA ELENI
Schizophrenia Disorders, Treatment Resistant Hallucinations
Cognitive and Metacognitive Evaluation in VR-Based Avatar Therapy for Psychosis
This study aims to evaluate the relationship between cognitive, metacognitive and social cognition variables in patients with psychosis undergoing VR-based Avatar Therapy for the treatment of auditory hallucinations.
- Trial name
- Meta-VR-AVATAR (NCT07091344)
- Testing
- VR-Based Avatar Therapy with Cognitive and Metacognitive Assessments
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Fundació Sant Joan de Déu
Cognition - Other
Post Stroke Cognitive Impairment
clinical evaluation of the prevalence and severity of cognitive impairment among patients after ischemic and haemorrhagic stroke admitted to the Neuropsychiatry department
- Trial name
- NCT07320300
- Testing
- Cognitive assessment: Montreal Cognitive Assessment (MoCA), Cognitive Assessment for Stroke patients, Oxford cognitive screening, Trail Making Test B, Digit Span-Backward, verbal fluency, Clinical Dem
- Volunteers
- 400 people
- Sponsor
- Assiut University
Schizophrenia, Schizoaffective Disorder
Serotonin 1A Agonists and Cognition in Schizophrenia
Examines cognitive functioning in patients with schizophrenia or schizoaffective disorder who have been treated with antipsychotic medications.
- Trial name
- NCT00178971
- Testing
- adjunctive treatment with buspirone
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Northwestern University
Parkinson Disease
A Study of Tolerability and Efficacy of Cannabidiol on Motor Symptoms in Parkinson's Disease
The major purpose of this study is to assess the efficacy of CBD on motor symptoms of Parkinson's Disease (PD), and secondarily to study the safety and tolerability of CBD and other efficacy, particularly regarding tremor in PD.
- Trial name
- NCT03582137
- Testing
- Cannabidiol
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- University of Colorado, Denver
Schizophrenia
Metformin Treatment on Cognitive Impairment of Schizophrenia
In this study, the investigators will investigate the effect and the underlying mechanism of metformin treatment on cognitive impairment in individuals with schizophrenia.
- Trial name
- NCT05838573
- Testing
- Metformin treatment, Baseline assessments, Volunteer assessments
- Where
- 4 sites in China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Central South University
Schizophrenia
A Study of the Effectiveness and Safety of Galantamine Hydrobromide on Cognitive Impairment in Patients With Schizophrenia.
The purpose of this study is to determine if adding extended-release galantamine hydrobromide, compared with adding placebo, to current atypical antipsychotic therapy is well tolerated and effective in improving cognitive…
- Trial name
- NCT00077727
- Testing
- Extended-release galantamine hydrobromide
- Volunteers
- 107 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Schizophrenia, Schizoaffective Disorder
Antipsychotic Effects on Brain Function in Schizophrenia
The purpose of the study is to determine whether two commonly-prescribed antipsychotic medications (aripiprazole and risperidone) have different effects on brain function and cognition in schizophrenia patients.
- Conditions
- Schizophrenia, Schizoaffective Disorder, Schizophreniform Disorder
- Trial name
- APD (NCT01913327)
- Testing
- Aripiprazole, Risperidone, Modafinil
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of California, San Francisco
Schizophrenia Disorders, Cognitive Impairment
Occurrence and Influencing Factors of Cognitive Impairment in Elderly Patients With Schizophrenia and
ACT combined with stratified intervention improved cognitive function and quality of life in elderly schizophrenia patients by enhancing psychological flexibility and family support.
- Conditions
- Schizophrenia Disorders, Cognitive Impairment, Acceptance and Commitment Therapy
- Trial name
- NCT06949657
- Testing
- the conventional treatment group, the ACT group
- Where
- China
- Volunteers
- 78 people
- Sponsor
- Third People's Hospital, Huzhou City, Zhejiang Province, China
Schizophrenia
Bifrontal and Bitemporal Electroconvulsive Therapy (ECT) in Treatment of Patients With Schizophrenia
Electroconvulsive therapy has been used in clinical practice since 1938, a number of randomized trials found significant differences favoring ECT in response rates between individuals with depression receiving real and sham ECT.
- Trial name
- ESBECT (NCT02511509)
- Testing
- Bifrontal electroconvulsive therapy, Bitemporal electroconvulsive therapy
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Medical University of Lodz
Schizophrenia
Can we Forget? Directed Forgetting and Embodied Cognition in Schizophrenia
Based on the theory of embodied cognition, which focuses on the influence of sensory and motor processes on cognition, researchers propose to study the influence of the action on memorization and inhibition in patients suffering…
- Trial name
- NCT02538445
- Testing
- Memorization of the verbs by miming the action, Memorization of the verbs by imagining the action, Memorization of the action verbs by means of another word
- Where
- France
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Schizophrenia
A Multicenter Study of NAP (AL-108) in Schizophrenia
The TURNS is a NIMH-funded contract for the evaluation of new compounds for the treatment of cognitive impairments in schizophrenia (HHSN 27820044 1003C; P.I.: Steve Marder, M.D.).
- Trial name
- AL-108 (NCT00505765)
- Testing
- AL-108
- Where
- 8 sites in United States
- Volunteers
- 63 people
- Sponsor
- University of California, Los Angeles
Schizophrenia, Cognitive Impairment
Functional Magnetic Resonance Imaging Study in Schizophrenia Patients and Correlation With Cognitive Impairments
1. Comparison of functional activity at different brain areas related to different cognitive domains e.g. Memory, visuospatial abilities, executive functions, attention, concentration, language, orientation in schizophrenia to…
- Trial name
- NCT06471179
- Testing
- Functional MRI
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assiut University
Schizophrenia
Neuroendocrine and Metabolite Substrates in Schizophrenia
Background: Schizophrenia is a serious mental illness. The diagnosis and severity evaluations of schizophrenia are generally based on patient behaviors.
- Trial name
- NCT02423096
- Testing
- Risperidone
- Where
- Taiwan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Schizophrenia
A Pilot Trial of Acute N-Acetylcysteine Effects on Working Memory and Other Cognitive Functions in Schizophrenia
The purpose of this study is to evaluate the effects of the amino acid supplement N-Acetylcysteine versus placebo on working memory and other cognitive functions in persons with a diagnosis of schizophrenia.
- Trial name
- NAC (NCT01232790)
- Testing
- N-Acetylcysteine
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Yale University
Psychotic Disorders, Cognitive Impairment
Cognitive Impairments in Psychotic Disorders
Patients with Psychotic disorders (Schizophrenia, Bipolar disorder and Schizoaffective disorder) often suffer from significant cognitive impairments, however how these develop and change over time before and after the first…
- Trial name
- NCT05597579
- Testing
- DAPAR Tests (IQ equivalent test)
- Where
- Israel
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Schizophrenia, Schizophreniform Disorder
Improving Cognition Through Telehealth Aerobic Exercise and Cognitive Training After a First Schizophrenia Episode
The participants in the study will receive psychiatric treatment at the UCLA Aftercare Research Program. All participants in this 12-month RCT will receive cognitive training.
- Conditions
- Schizophrenia, Schizophreniform Disorder, Schizoaffective Disorder
- Trial name
- NCT05890183
- Testing
- Cognitive training, Aerobic Exercise Program, Moderated Online Social Therapy (MOST)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of California, Los Angeles