Clinical trials: Cognition - Other
Schizophrenia, Schizoaffective Disorder
Zyprexa and Task Engagement in Schizophrenia
Individuals with schizophrenia frequently have impairments in attention. These impairments have been shown to be related to overall functioning.
- Trial name
- NCT00440843
- Testing
- Olanzapine (Zyprexa), Typicals
- Where
- United States
- Sponsor
- VA Connecticut Healthcare System
Schizophrenia
Identification and Treatment of the Liability to Develop Schizophrenia
This study seeks to determine whether adult, non-psychotic, first-degree relatives of schizophrenic patients who show specific neurocognitive deficits and negative symptoms will show improvements in these areas following a…
- Trial name
- NCT00305474
- Testing
- Risperidone
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Central South University
Schizophrenia, Schizoaffective Disorder
Adjunctive Treatment for Decreasing Symptoms of Schizophrenia
This study will determine the effectiveness of treatment with glycine or d-cycloserine in addition to a normal antipsychotic regimen in improving negative symptoms and cognitive impairments in patients with schizophrenia.
- Trial name
- NCT00222235
- Testing
- d-cycloserine, glycine
- Where
- 5 sites in United States, Israel
- Volunteers
- 240 people
- Sponsor
- University of Maryland, Baltimore
Schizophrenia, Schizoaffective Disorder
Assessing the Effects of Fanapt® on Social Cognition in Schizophrenia
The study looks at whether treatment with iloperidone (Fanapt) is associated with improvements in social cognition in individuals who have been recently diagnosed with schizophrenia or schizoaffective disorder.
- Trial name
- NCT01929889
- Testing
- Iloperidone
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Northwestern University
Schizophrenia, Psychotic Disorder
tDCS for Cognitive Impairment Associated With Recent-onset Schizophrenia
Background: In parallel to the traditional symptomatology, deficits in cognition (memory, attention, reasoning, social functioning) contribute significantly to disability and suffering in individuals with schizophrenia.
- Trial name
- STICOG (NCT05440955)
- Testing
- left fronto-temporal transcranial Direct Current Stimulation (tDCS)
- Where
- 4 sites in France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Grenoble
Psychotic Disorders, Schizophrenia
Effect of Individual Cognitive Stimulation at Home in Adults With Psychotic Disorders
The aim of this study is to test the effect of cognitive stimulation (CS), applied individually and at home, on the overall cognitive functioning, emotional state, functionality, and quality of life (QoL) in adults with psychotic…
- Conditions
- Psychotic Disorders, Schizophrenia, Schizoaffective Disorder, Delusional Disorder
- Trial name
- NCT04783285
- Testing
- Individual cognitive stimulation therapy (iCST)
- Where
- Portugal
- Volunteers
- 38 people
- Sponsor
- CEDIARA - Assoc. Solidariedade Social de Ribeira de Fráguas
Schizophrenia and Schizoaffective Disorder
Relationship Between Physical Fitness and Psychopathology, Cognition and Quality of Life in Patients Diagnosed With Schizophrenia: a Mixed Method Study.
The goal of this observational study is to assess the physical fitness and the influence of possible factors (disease symptomatology, cognitive status, patient functioning and degree of perceived quality of life) on patients…
- Trial name
- COFESQ (NCT06824584)
- Where
- Spain
- Volunteers
- 45 people
- Sponsor
- Universidade da Coruña
Schizophrenia; Psychosis, Cognitive Impairment
A Study Evaluating the Efficacy of Xanomeline/Trospium (XT) on Cognitive Impairment After 24 and 52 Weeks of Treatment in Adult Participants With Schizophrenia
Schizophrenia is a long-lasting and serious mental health disorder that affects about 1% of people worldwide. It can cause symptoms such as hallucinations and delusions (called positive symptoms), confused or disorganized…
- Trial name
- SHINE (NCT07084831)
- Testing
- Xanomeline/trospium
- Where
- 16 sites in Austria, Belgium and 8 more
- Volunteers
- 171 people
- Sponsor
- European Group for Research In Schizophrenia
Schizophrenia
The Effects of Varenicline on Cognitive Function in Patients With Schizophrenia
The primary objective of this project is to examine the effects of varenicline treatment used concomitantly with antipsychotic medications, on cognitive dysfunction in people with schizophrenia.
- Trial name
- NCT00523445
- Testing
- Varenicline(Chantix)
- Where
- 5 sites in South Korea
- Volunteers
- 120 people
- Sponsor
- Inje University
Other Eating Disorders
Awakening to the Taste of Food Among Restrained Women
Energy-restricted diets often require dieting rules, which forced the dieter to eat according to cognitive norms, which increase his vulnerability to external food cues.
- Trial name
- Flaveur (NCT01535846)
- Testing
- Conscious food tasting intervention
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Laval University
Psychosis
USS Training to Improve Social Function in People With Psychosis
Psychotic spectrum disorders (PSD) are associated with poor social function. By doing this study, the investigators hope to learn which of two different types of 2-month long training courses is more effective in improving…
- Trial name
- NCT04557124
- Testing
- USS, MovingForward
- Where
- United States
- Volunteers
- 113 people
- Sponsor
- VA Office of Research and Development
Schizophrenia
Discriminant Validity of the Multiple Errands Test in Schizophrenia
Schizophrenia (SZ) is a chronic, severe disease resulting in a misperception of reality, major social withdrawal and cognitive disturbances.
- Trial name
- VALITEM (NCT02782091)
- Testing
- Multiple Errands Test (MET)
- Where
- France
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Repetitive Transcranial Magnetic Stimulation (rTMS), Schizophrenia
Effects of Repetitive Transcranial Magnetic Stimulation (rTMS) on Cannabis Use and Cognitive Outcomes in Schizophrenia
The high prevalence of cannabis and other substance use disorders are a major barrier to recovery in people with schizophrenia. Moreover, schizophrenia patients have significant deficits in cognitive function, which may be…
- Conditions
- Repetitive Transcranial Magnetic Stimulation (rTMS), Schizophrenia, Cannabis Use Disorder, Cognition
- Trial name
- rTMSCANSZ (NCT03189810)
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS), Weekly Counselling Session
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- Centre for Addiction and Mental Health
Psychosis
Psychosis TMS Study
The main goal of this study is to investigate the neural mechanisms of working memory function in patients with early psychosis using Transcranial Magnetic Stimulation (TMS) in conjunction with functional MRI.
- Trial name
- NCT05857137
- Testing
- Active TMS
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Massachusetts General Hospital
Schizophrenia
Clinical Trial of BI 425809 Effect on Cognition and Functional Capacity in Schizophrenia
The objective of the study is to investigate the efficacy, safety and pharmacokinetics of four different doses of BI 425809 once daily compared to placebo given for 12 weeks in patients with schizophrenia on stable antipsychotic…
- Trial name
- NCT02832037
- Testing
- BI 425809 dose 1, BI 425809 dose 2, BI 425809 dose 3
- Where
- 81 sites in United States, Austria and 9 more
- Volunteers
- 509 people
- Sponsor
- Boehringer Ingelheim
Schizophrenia
Efficacy Study of GAÏA Program Cognitive Remediation of Facial Affects Processing in Schizophrenia
Social cognition impairments was highlighted for persons suffering with schizophrenia by numerous studies. The use of treatment programs intended to treat specifically these deficits through procedures of cognitive remediation…
- Trial name
- NCT02110771
- Testing
- GAÏA - facial affect recognition targeted, RECOS - attentional process targeted
- Where
- France
- Volunteers
- 33 people
- Sponsor
- Hôpital le Vinatier
Schizophrenia
Paired Associative Stimulation in the Dorsolateral Prefrontal Cortex in Patients With Schizophrenia
The purpose of this study is to 1. assess the effect of PAS in schizophrenia in the dorsolateral prefrontal cortex (DLPFC) 2. assess the effect of PAS induced long-term potentiation (LTP) on the performance of patients with…
- Trial name
- NCT01545999
- Testing
- Brain Stimulation via Transcranial Magnetic Stimulation
- Where
- Canada
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health
Schizophrenia, Bipolar Disorder
Brain Network Mechanisms of Cognitive Impairments in Major Psychiatric Disorders and Their Clinical Applications
Previous and our studies have shown that cognitive impairments are core symptoms of three major psychiatric disorders-schizophrenia, bipolar disorder, and major depressive disorder, and are associated with underlying brain…
- Conditions
- Schizophrenia, Bipolar Disorder, Major Depressive Disorder (MDD)
- Trial name
- NCT07444463
- Testing
- repetitive transcranial magnetic stimulation (rTMS)
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Central South University
Diabetes, Pre-diabetes
Northern Manhattan Study of Metabolism and Mind
Pre-diabetes, type 2 diabetes, and their related conditions, adiposity and insulin resistance, are more prevalent in minorities Northern Manhattan compared to the general population of the United States.
- Conditions
- Diabetes, Pre-diabetes, Cognition - Other, Depressive Symptoms
- Trial name
- NOMEM (NCT02470260)
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Columbia University
Schizophrenia
Different Safety Profile of Risperidone and Paliperidone Extended-release
The main objective of this study was to assess subjective experiences related to secondary negative symptoms and cognitive performance in healthy volunteers in response to multiple doses of paliperidone ER and risperidone in a…
- Trial name
- NCT01284959
- Testing
- risperidone, paliperidone ER
- Where
- South Korea
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Chonbuk National University Hospital