Clinical trials: Cognition Disorders in Old Age
Mild Cognitive Impairment (MCI), Moderate Cognitive Impairment
Comparative Effects of Integrated Versus Sequential Approaches to Dual-Task Training in Elderly With Mild to Moderate Cognitive Impairment
Mild and Moderate cognitive impairment is a condition characterized by a noticeable decline in cognitive abilities, including memory and thinking skills, which is greater than expected for an individual's age but does not…
- Trial name
- nill (NCT07775079)
- Testing
- Integrated Dual-Task Training, Sequential Dual-Task Training
- Where
- Pakistan
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Shifa Tameer-e-Millat University
Postoperative Cognitive Dysfunction
Postoperative Cognitive Dysfunction in Elderly
Interventional Study of Early Postoperative Cognitive Dysfunction in Elderly Patients Undergoing General Anesthesia The main purpose of this study is to determine the incidence of early postoperative cognitive dysfunction in…
- Trial name
- ElderlyPOCD (NCT02068742)
- Testing
- battery neuropsychological tests
- Where
- Italy
- Volunteers
- 160 people
- Sponsor
- Università degli Studi dell'Insubria
Cognitive Dysfunction
Efficacy and Safety of Cytoflavin® Used in Elderly Patients for the Prevention of Cognitive Decline After Major Surgery
Postoperative cognitive impairment develops in the early and continues in the late postoperative period; it is manifested by impaired memory, attention, concentration and other higher cortical functions (thinking, speech).
- Trial name
- NCT03849664
- Testing
- Cytoflavin® solution, Cytoflavin® enteric-coated tablet
- Where
- 13 sites in Russia
- Volunteers
- 200 people
- Sponsor
- POLYSAN Scientific & Technological Pharmaceutical Company
The Effectiveness of Precision Nursing Intervention Program on Cognitive Function、Sleep Quality and Emotional State of Frail Femal Elderly in the Community
Precision Nursing Intervention Program on Cognitive Function、Sleep Quality and Emotional State of Frail Female Elderly
Background: Taiwan's community population is aging rapidly, and women in the aging community account for the majority of frail elderly.In the process of aging, you must face changes in cognitive function, sleep disorders, and…
- Trial name
- NCT04902716
- Testing
- Design course
- Where
- Taiwan
- Volunteers
- 70 people
- Sponsor
- National Taipei University of Nursing and Health Sciences
Accidental Falls
The HIP-HOP Flooring Study: Helping Injury Prevention in Hospitalised Older People
In hospitals, older people can fall and hurt themselves. The investigators want to see if a new type of flooring can help stop people hurting themselves as badly, if they accidentally fall.
- Trial name
- NCT00817869
- Testing
- New flooring
- Where
- 8 sites in United Kingdom
- Volunteers
- 571 people
- Sponsor
- University of Portsmouth
Postoperative Cognitive Dysfunction
Optimization of Desflurane in Elderly Patients
Various issues had been pointed out when undergoing the anesthesia for elderly patients with sevoflurane, such as delayed emergence, post-operative trouble with swallowing.
- Trial name
- NCT01700907
- Testing
- Desflurane, Sevoflurane
- Where
- Japan
- Volunteers
- 20 people
- Sponsor
- Sapporo Medical University
Alzheimer Disease, Mild Cognitive Impairment
Early Diagnosis of Alzheimer-like Dementia: Benefit of MRI and PET Imaging
The physio-pathology of Alzheimer's disease (AD) remains unknown and there is no cure. Thus, the search for objective markers of preclinical first signs of cognitive impairment, is currently a major public health issue.
- Conditions
- Alzheimer Disease, Mild Cognitive Impairment, Vascular Dementia
- Trial name
- NCT01815112
- Testing
- Magnetic resonance imaging, Positron emission tomography
- Where
- 2 sites in France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Dementia, Cognitive Impairment
Prevalence and Recognition of Geriatric Syndrome in Outpatient Clinic at Srinagarind Hospital
The purpose of this study is to collect the prevalence of geriatric syndrome, which is recognized by an internist, and to compare the data based on the comprehensive geriatric assessment by a geriatrician.
- Conditions
- Dementia, Cognitive Impairment, Depression, Urinary Incontinence
- Trial name
- NCT00892086
- Where
- Thailand
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Khon Kaen University
Cognitive Decline
Effects of Multidomain Intervention on Cognitive Function in Community-dwelling Elderly
The aging population has contributed to an increase in cognitive decline. To mitigate the rise in the dementia population, it is crucial to prevent cognitive decline in older adults with normal functioning, subjective cognitive…
- Trial name
- NCT06180161
- Testing
- multidomain intervention
- Where
- Taiwan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Diabetes Mellitus, Diabetic Peripheral Neuropathy
Neuropathic Pain in Elderly People With Diabetes: Impact on Quality of Life and Cognition
This study was set out 1) Evaluate the impact of Diabetic Peripheral Neuropathy (DPN) and DPN-P (Diabetic Peripheral Neuropathic Pain) on the overall Quality of Life (QoL) in elderly with Diabetic Mellitus (DM) and 2) Evaluate…
- Conditions
- Diabetes Mellitus, Diabetic Peripheral Neuropathy, Cognitive Impairment, Quality of Life
- Trial name
- NCT03909841
- Testing
- Cambridge Neuropsychological Test Automated Battery (CANTAB), Chinese (Hong Kong) 12-item Short-Form Health Survey (version 2)
- Where
- Hong Kong
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Queen Elizabeth Hospital, Hong Kong
Femoral Neck Fractures, Postoperative Complications
Postoperative Recovery in Elderly Patients Undergoing Hip Hemi-arthroplasty
Hip fractures incidence grows rapidly with the aging of the population. After indicated surgical treatment, hip fracture patients experience high rates of postoperative complications, postoperative delirium (PD), postoperative…
- Conditions
- Femoral Neck Fractures, Postoperative Complications, Inflammatory Response, Postoperative Delirium
- Trial name
- NCT01934049
- Testing
- hip arthroplasty, Total Intravenous Anesthesia and Peripheral nerve blocks
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Chinese PLA General Hospital
Anesthesia, Hip Fractures
Anesthesia and Perioperative Neurocognitive Disorders in the Elderly Patients Undergoing Hip Fracture Surgery Platform Trial (ANDES Platform Trial)
The ANDES Platform Trial is a pragmatic, multicenter, adaptive randomized controlled platform trial in patients aged 65 years or older undergoing surgery for hip fracture.
- Conditions
- Anesthesia, Hip Fractures, Dementia, Cognitive Impairment
- Trial name
- ANDES platform (NCT06452147)
- Testing
- Nerve block, Standard anesthesia care, Bupivacaine liposome
- Where
- 13 sites in China
- Volunteers
- 1,860 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Postoperative Delirium, Postoperative Cognitive Dysfunction
The Impact of Repetitive Transcranial Magnetic Stimulation on the Prognosis of Elderly Surgical Patients
Exploring the effects of repeated transcranial magnetic stimulation (rTMS) during the perioperative period on the incidence of postoperative delirium, postoperative cognitive dysfunction, and chronic postoperative pain in elderly…
- Conditions
- Postoperative Delirium, Postoperative Cognitive Dysfunction, Chronic Post-surgical Pain
- Trial name
- NCT06392919
- Testing
- Repetitive Transcranial Magnetic Stimulation
- Where
- China
- Volunteers
- 352 people
- Sponsor
- Affiliated Hospital of Nantong University
Geriatric, Elderly
Validity and Reliability of the Turkish Form of the Enjoyment of Physical Activity Scale-8 in Geriatrics With Minimal Cognitive Impairment
The main objective of this study is to examine the validity and reliability of the Turkish form of the Enjoyment of Physical Activity Scale-8 (PACES-8) in individuals aged 65 and over with Minimal Cognitive Impairment (MCI).
- Conditions
- Geriatric, Elderly, Cognitive Abnormality
- Trial name
- NCT07588685
- Testing
- Assessments
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Cognitive Impairment, Cognitive Decline
Multicentre Study About the Effect of Individual Reminiscence Therapy
This study aims to evaluate the effect of individual reminiscence therapy (RT) on the global cognitive function of people with neurocognitive disorders attending social responses and to evaluate the ability of individually…
- Conditions
- Cognitive Impairment, Cognitive Decline, Dementia, Neurocognitive Disorders
- Trial name
- NCT04047238
- Testing
- Reminiscence Therapy
- Where
- 25 sites in Portugal
- Volunteers
- 251 people
- Sponsor
- Rsocialform - Geriatria, Lda
Aging, Mild Cognitive Impairment
A Study of Characterizing Cognitive Decline and Functional Cardiac Senescence in Healthy Korean Volunteers
Although aging process appears to be generally characterized, investigators have been paid much attention to the specific target molecules, which leads to discover the clinical markers of the senescence.
- Conditions
- Aging, Mild Cognitive Impairment, Angina Pectoris
- Trial name
- NCT01590706
- Where
- South Korea
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Korea Institute of Oriental Medicine
Depression in Old Age, Recurrence
Recurrence Markers, Cognitive Burden and Neurobiological Homeostasis in Late-Life Depression
Late-life depression (LLD) is associated with disability, increased risk for cognitive decline and dementia, elevated suicide risk, and greater all-cause mortality.
- Conditions
- Depression in Old Age, Recurrence, Cognitive Dysfunction
- Trial name
- REMBRANDT (NCT05331599)
- Where
- United States
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Cognitive Decline, Memory Loss
Effects of Music and Dance on Cognition, Frailty, and Burden in Elderly Caregivers Living in Rural Communities
This research aims to analyze the effects of senior dance on the cognition, frailty, and burden in elderly caregivers of rural communities.
- Conditions
- Cognitive Decline, Memory Loss, Frail Elderly Syndrome, Burden, Dependency
- Trial name
- NCT03068299
- Testing
- Dance, Health care guidance
- Where
- Brazil
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Sao Carlos
Frail Elderly, Cognitive Impairment
A Community Health Worker Program to Support Rural Older Adults
This study will investigate an intervention delivered by community health workers for older adults with signs of cognitive impairment, mobility loss, and depression in the rural primary care setting.
- Conditions
- Frail Elderly, Cognitive Impairment, Mobility Limitation, Depressive Symptoms
- Trial name
- NCT03843333
- Testing
- Tai Ji Quan: Moving for Better Balance, Behavioral Activation, Resource Navigation
- Where
- 3 sites in United States
- Volunteers
- 39 people
- Sponsor
- University of Vermont
Vestibular Dysfunction, Dizziness
Vestibular Balance-Cognition Dual-Task Digital System: Development of a Smart Rehabilitation Platform for the Elderly and Prediction of Balance Function Risks
This study is being done to better understand how vestibular problems and thinking abilities (such as attention and mental flexibility) are related in older adults, and how doing a balance task and a thinking task at the same…
- Conditions
- Vestibular Dysfunction, Dizziness, Falls (Accidents) in Old Age, Balance Assessment
- Trial name
- NCT07735078
- Testing
- Instrumented balance and gait assessment using wearable inertial sensors, Questionnaires and paper-based cognitive tests
- Where
- Taiwan
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University