Clinical trials: Cognition Disorders in Old Age
Frail Elderly Syndrome, Sarcopenia
Leucine Supplementation in Sarcopenic Older Individuals
Caring with older people in west societies has becoming a challenge for all health professional and any measure that can increase health or well-being will be ultimately improve quality of life and life expectancy.
- Trial name
- NCT03831399
- Testing
- Leucine
- Where
- Spain
- Volunteers
- 59 people
- Sponsor
- University of Valencia
Mild Cognitive Impairment (MCI)
Gamma tACS to Improve Cognitive Function in Mild Cognitive Impairment
Mild cognitive impairment (MCI) is a decline in memory and thinking that exceeds normal aging but does not substantially disrupt daily life, and it raises the risk of developing dementia.
- Trial name
- TACS-MCI (NCT07752316)
- Testing
- transcranial electrical stimulation
- Where
- Iran
- Volunteers
- 30 people
- Sponsor
- The National Brain Mapping Laboratory (NBML)
Dementia, Alzheimer Disease
Evaluation of Alteration by Magnetic Resonance Imaging (MRI) in Dementia Among Elderly Subjects
Capturing the earliest stages of Dementia especially Alzheimer's Disease (AD) is a great challenge. Until now the NINCDS-ADRDA and the DSM criteria for AD were largely used as diagnostic standards in research.
- Trial name
- AMIMAGE (NCT00951197)
- Testing
- Neuroimaging
- Where
- France
- Volunteers
- 318 people
- Sponsor
- University Hospital, Bordeaux
Mild Cognitive Impairment
Effectiveness of an ACT-Based Cognitive Intervention on Quality of Life and Cognitive Function in Elderly Residents With MCI
This study investigates the effects of an Acceptance and Commitment Therapy (ACT)-based cognitive intervention on Quality of Life (QOL) and cognitive function among elderly residents with Mild Cognitive Impairment (MCI) in…
- Trial name
- EACT (NCT06753578)
- Testing
- Acceptance and Commitment Therapy (ACT), standard care
- Where
- Spain
- Volunteers
- 215 people
- Sponsor
- Instituto de Investigación Marqués de Valdecilla
Frail Elderly, Cognitive Impairment
Effectiveness of a Multifactorial Intervention on Frailty
Objective: To evaluate the effectiveness of a multifactorial intervention program based on physical activity and diet, memory workshops and review of medication, to modify frailty parameters, muscle strength and physical and…
- Conditions
- Frail Elderly, Cognitive Impairment, Dependence
- Trial name
- NCT01969526
- Testing
- Multifactorial intervention
- Where
- Spain
- Volunteers
- 352 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Emergence Delirium, Perioperative Neurocognitive Disorder
Quantitative Neurofeedback Techniques for Treating Perioperative Cognitive Disorders in Elderly Patients
The goal of this clinical trial is to learn if quantitative measurement of brain and neurofeedback intervention techniques works to prevent perioperative neurocognitive deficits in elderly oncology patients who are to undergo…
- Trial name
- NCT06752148
- Testing
- neurofeedback intervention training game
- Volunteers
- 390 people
- Sponsor
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Living Alone, Alzheimer Disease
Living Alone in Old Age With Cognitive Impairment
The purpose of this study is to better understand the experience of living alone in older age with cognitive impairment. We recruit adults 55+ living alone with cognitive impairment such as Alzheimer's disease or mild cognitive…
- Conditions
- Living Alone, Alzheimer Disease, Mild Cognitive Impairment
- Trial name
- NCT03330587
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of California, San Francisco
Mild Cognitive Impairment (MCI)
Effect of Vırtual Realıty Glasses on Mıld Cognıtıve Impaırment in Elderly
This study was conducted in a randomized controlled manner to investigate the effect of VR glasses on mild cognitive impairment in the elderly.
- Trial name
- NCT06735352
- Testing
- virtual reality intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 12 people
- Sponsor
- Karadeniz Technical University
Type 2 Diabetes Mellitus
Gut-Brain-axis: Targets for Improvement of Cognition in the Elderly
Cognitive disorders increase with age and in the presence of metabolic diseases such as Type 2 Diabetes Mellitus (T2DM). In addition, digestive disorders, changes in dietary pattern and decreased activity negatively influence the…
- Trial name
- SmartAge (NCT04841668)
- Testing
- Metformin
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Institut d'Investigació Biomèdica de Girona Dr. Josep Trueta
Aging, Balance Control in Elderly
Effects of Telerehabilitation-Based Dual-Task Exercises on Balance, Fall Risk, Cognitive Function, and Sleep Quality in Geriatric Individuals
The purpose of this study is to investigate the effects of dual-task exercises-which simultaneously target cognitive and motor functions-delivered via telerehabilitation on fall risk, balance, cognitive functions, and sleep…
- Conditions
- Aging, Balance Control in Elderly, Sleep Disorder (Disorder)
- Trial name
- NCT07472101
- Testing
- Telerehabilitation Based Dual-Task Exercises, Educational Brochure and Phone Follow-Up
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Bulent Ecevit University
Eldery People, Cognitive Decline
Optimizing CNS DHA Delivery in Elderly Adults at Risk for Dementia
The purpose of this placebo-controlled trial is to compare the effects of 24-weeks supplementation with LPC-DHA and TAG-DHA on cerebrospinal fluid and blood DHA levels, as well as biomarkers of central neurodegenerative and…
- Conditions
- Eldery People, Cognitive Decline, Memory Decline, DHA CNS Delivery
- Trial name
- NCT06933095
- Testing
- LPC-EPA+DHA capsules containing omega-3 fatty acids EPA and DHA esterified to lysophosphatidylcholine (LPC-EPA+DHA)(Trade name: Lysoveta)
- Where
- United States
- Volunteers
- 153 people
- Sponsor
- University of Cincinnati
Mild Cognitive Impairment
Cognitive Impairment and Balance in Elderly
One important issue in older adults with cognitive problems is the higher risk of fall due to decreased motor function and balance.
- Trial name
- NCT02051270
- Testing
- Descriptive study
- Where
- Spain
- Volunteers
- 82 people
- Sponsor
- Universidad de Granada
Elderly Adults, Parkinson
A Treadmill Training Program Augmented by Virtual Reality to Decrease Fall Risk in Older Adults
The proposed randomized controlled trial will evaluate the effects of treadmill training augmented with virtual reality on fall risk. 300 older adults with a history of falls will be recruited to participate in this study.
- Conditions
- Elderly Adults, Parkinson, Mild Cognitive Disorder
- Trial name
- VTIME (NCT01732653)
- Testing
- TT+VR, TT alone
- Where
- 5 sites in Belgium, Israel and 3 more
- Volunteers
- 302 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Aging, Cognitive Decline
Social and Cognitive Online Training: the SCOT Project
Social isolation and reduced involvement in cognitive activities are associated with repercussions on cognitive well-being and health status in elderly adults.
- Trial name
- SCOT (NCT05023187)
- Testing
- SCOT, CON
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Università degli Studi di Trento
Dementia, Cognitive Impairment, Mild
Repeated Transcranial Magnetic Stimulation in the Elderly With Cognitive Impairment
Introduction and Purpose: In recent years, non-pharmacological treatment methods for dementia patients have been gradually explored.
- Trial name
- NCT06192433
- Testing
- High-frequency repetitive transcranial magnetic stimulation (40Hz), Moderately high-frequency repetitive transcranial magnetic stimulation (10Hz)
- Where
- Taiwan
- Volunteers
- 18 people
- Sponsor
- Taipei Hospital, Ministry of Health and Welfare
Functional Autonomy Level
Optimization of Drug Prescribing in an Elderly Population of Geriatric Consultations
Aging is often associated with multiple chronic conditions conducting increased consumption of drugs. Drug therapy is necessary for the treatment of many diseases.
- Trial name
- OPTIM (NCT02740764)
- Testing
- Optimization of drug prescribing
- Where
- 2 sites in France
- Volunteers
- 302 people
- Sponsor
- Hospices Civils de Lyon
The Effectiveness of Precision Nursing Intervention Program on Cognitive Function、Sleep Quality and Emotional State of Frail Femal Elderly in the Community
Precision Nursing Intervention Program on Cognitive Function、Sleep Quality and Emotional State of Frail Female Elderly
Background: Taiwan's community population is aging rapidly, and women in the aging community account for the majority of frail elderly.In the process of aging, you must face changes in cognitive function, sleep disorders, and…
- Trial name
- NCT04902716
- Testing
- Design course
- Where
- Taiwan
- Volunteers
- 70 people
- Sponsor
- National Taipei University of Nursing and Health Sciences
Aging, Mild Cognitive Impairment
A Study of Characterizing Cognitive Decline and Functional Cardiac Senescence in Healthy Korean Volunteers
Although aging process appears to be generally characterized, investigators have been paid much attention to the specific target molecules, which leads to discover the clinical markers of the senescence.
- Conditions
- Aging, Mild Cognitive Impairment, Angina Pectoris
- Trial name
- NCT01590706
- Where
- South Korea
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Korea Institute of Oriental Medicine
Mild Cognitive Impairment
Acupoint Massage and Aromatherapy Intervention in Elderly People With Mild Cognitive Impairment in Nursing Institutions
This study aims to investigate and compare the intervention effects of acupressure,aromatherapy,combining acupressure and aromatherapy in elderly with mild cognitive impairment.
- Trial name
- NCT03857269
- Testing
- Acupoint Massage, lavender essential oil, Acupoint Massage and lavender essential oil
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Huan Ding
Dementia, Neurocognitive Disorders
Prefrontal Cortex Dynamics of the Elderly During a Cognitive Stimulation Programme
This research aims to evaluate the effect of cognitive stimulation (CS) on the functioning of the prefrontal cortex (PFC), seeking an analysis of both cerebral hemodynamics in neuroplasticity and aspects related to the initiation…
- Conditions
- Dementia, Neurocognitive Disorders, Cognitive Impairment, Cognitive Dysfunction
- Trial name
- NCT04693611
- Testing
- Individual cognitive stimulation therapy (iCST), Functional near-infrared spectroscopy (fNIRS)
- Where
- Portugal
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- CEDIARA - Assoc. Solidariedade Social de Ribeira de Fráguas