Clinical trials: Cognition Disorders in Old Age
Mild Cognitive Impairment (MCI), Depression
Brain Aging and Treatment Response in Geriatric Depression
The proposed project will evaluate the role of neuroimaging biomarkers of brain aging (i.e., neurodegenerative and vascular brain changes) and mild cognitive impairment in the patterns of treatment response to memantine combined…
- Trial name
- NCT01902004
- Testing
- Escitalopram, Memantine
- Where
- United States
- Volunteers
- 115 people
- Sponsor
- University of California, Los Angeles
Alzheimer's Disease
Utilization of Exergame Programs Among Elderly Residents in Rural Nursing Care Centers
Background: Cognitive impairment is prevalent among older adults and frequently misdiagnosed or diagnosed late, increasingly drawing attention as a significant health issue in aging populations.
- Trial name
- NCT06717971
- Testing
- Exergame-based multicomponent training program., Standard care
- Where
- China
- Volunteers
- 232 people
- Sponsor
- Aoyu Li
Mild Cognitive Impairment, So Stated, Mild Dementia
Cognitive/Physical Computer-Game Blended Training of Elderly: Neuroscientific LLM Studies
The study involved Information and Communication Technologies (ICT) and more specifically computer exercises blended with game activities.
- Conditions
- Mild Cognitive Impairment, So Stated, Mild Dementia, Healthy
- Trial name
- LLM-AUTH (NCT02313935)
- Testing
- LLM, FFA, Brain Fitness
- Volunteers
- 581 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Aged 65 Years or Older, Cognitive Decline
The Effect of Occupational Activities and Finger Exercise Program on Hand Grip Strength and Activities of Daily Living in Elderly Individuals With Dementia: Randomized Controlled Trial
As people age, cognitive functions, muscle mass, and hand strength tend to decrease. Reduced hand grip strength in the elderly can make it harder for them to perform daily tasks such as buttoning clothes, pulling zippers, or…
- Conditions
- Aged 65 Years or Older, Cognitive Decline, Dementia
- Trial name
- NCT07033338
- Testing
- Occupational Activities and Finger Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Emel Dogan
Cognitive Dysfunction, Alzheimer Disease
Association of Transcranial Alternating Current Stimulation with Digital Cognitive Training for Cognitive Remediation in Older Adults
BACKGROUND Cognitive decline in older adults, especially those who develop Mild Cognitive Impairment and Alzheimer's Disease, currently has limited options of pharmacological treatments, with modest efficacy.
- Conditions
- Cognitive Dysfunction, Alzheimer Disease, Mild Cognitive Impairment, Cognitive Decline
- Trial name
- NCT06733714
- Testing
- Transcranial Alternating Current Stimulation, Digital Cognitive Training
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio de Janeiro
Post-Operative Confusion
Braindex Cerebral Tissue Oxygen Saturation (SctO2) Measurement Algorithm Assessment and Improvement
The objective of this clinical trial is to optimize Braindex brain tissue oxygen saturation (SctO2) measurement algorithm compared to a mixed reference value of jugular venous and systemic arterial saturation, during proven…
- Trial name
- POC-SctO2 (NCT05897060)
- Testing
- Venus Jugular O2 Saturation optical fiber
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Braindex
Dementia, Cognitive Impairment, Mild
Repeated Transcranial Magnetic Stimulation in the Elderly With Cognitive Impairment
Introduction and Purpose: In recent years, non-pharmacological treatment methods for dementia patients have been gradually explored.
- Trial name
- NCT06192433
- Testing
- High-frequency repetitive transcranial magnetic stimulation (40Hz), Moderately high-frequency repetitive transcranial magnetic stimulation (10Hz)
- Where
- Taiwan
- Volunteers
- 18 people
- Sponsor
- Taipei Hospital, Ministry of Health and Welfare