Clinical trials: Cognitive Aging
Aging, Fall Risk Factors
Use of Virtual Reality for the Assessment of Attentional and Reaction Abilities for Fall Risk Evaluation
Aging is a condition characterized by a general decline in physical and cognitive performance, however its effects on various functions are still controversial.
- Conditions
- Aging, Fall Risk Factors, Sleep
- Trial name
- NCT06940245
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Alzheimer Disease, Old Age; Dementia
Blood Biomarkers for Alzheimer Disease and Neuro-injury to Estimate the Association With Cognitive/Functional Decline and Mortality in a Real-world Population of GERiatric Hospitalized Patients (BAD-GER)
The BAD-GER study is a multicenter, prospective, three-arm observational study serving to validate a prognostic biomarker algorithm for mortality and hospital readmission; this algorithm will be developed through the…
- Trial name
- BAD-GER (NCT07435467)
- Testing
- collection of blood samples
- Where
- 3 sites in Italy
- Volunteers
- 400 people
- Sponsor
- Istituto Nazionale di Ricovero e Cura per Anziani
TBI (Traumatic Brain Injury), Rehabilitation
Effectiveness of Multimodal Cognitive Rehabilitation for Traumatic Brain Injury Sustained During Older Adulthood
In a worldwide context of accelerated demographic aging, traumatic brain injury (TBI) in older adults has become a public health problem.
- Conditions
- TBI (Traumatic Brain Injury), Rehabilitation, Aging
- Trial name
- NCT04590911
- Testing
- Cognitive Enrichment Program (CEP)
- Where
- Canada
- Volunteers
- 42 people
- Sponsor
- Centre for Interdisciplinary Research in Rehabilitation of Greater Montreal
Healthy Aging
Neuroathletic Exercise In The Elderly
Objective: The aim of this protocol study was to investigate the effect of neuroathletic exercise on walking speed, fall risk and cognitive function in the elderly.
- Trial name
- NCT07070336
- Testing
- Neuroathletic exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- KTO Karatay University
Healthy
Diet and the Aging Brain
We investigate whether a change in diet could provide positive effects on general brain functions in healthy elderly people.
- Trial name
- NCT00463255
- Testing
- diet
- Where
- Germany
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Hospital Muenster
Healthy Aging
The Aerobic and Cognitive Training System
This study will determine the effects of simultaneous exercise and cognitive training on cognitive function in healthy older adults.
- Trial name
- NCT04120792
- Testing
- Simultaneous exercise and cognitive training, Exercise training, Cognitive Training
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Alzheimer Disease, Aging
Lifestyle for the BRAin Health - Time Restricted Eating and Mindfulness
The study aims to evaluate the effects of a 9-month intervention combining yoga-based mindfulness techniques, cognitive training, and nutritional counseling on cognitive function, plasma markers of neurodegeneration (tau…
- Conditions
- Alzheimer Disease, Aging, Lifestyle Factors, Cognitive Impairment
- Trial name
- LIBRA REMIND (NCT07042087)
- Testing
- Mindfulness Yoga, Time-Restricted Eating with nutritional counseling promoting a flexitarian dietary pattern, Cognitive Training
- Where
- Czechia
- Volunteers
- 48 people
- Sponsor
- St. Anne's University Hospital Brno, Czech Republic
Cognitive Dysfunction, Cognitive Disorder, Dietary Supplements
INSIDE: Intervention in Nutritional Supplementation to Improve Cognitive Decline in Elderly.
This study investigates the effect of nutritional supplementation on cognitive performance in older adults over a 90-day period using a double-blind randomized controlled design.
- Trial name
- INSIDE (NCT07000500)
- Testing
- Nutritional Supplement
- Where
- Portugal
- Volunteers
- 50 people
- Sponsor
- Maria Paço
Healthy Aging, Cognitive Benefits
Cardiorespiratory Fitness and Acute High-Intensity Exercise Effects on Brain and Cognitive Function in Older Adults
The goal of this clinical trial is to learn whether a single session of high-intensity interval exercise (HIIT) affects cognitive performance and brain activity in older adults, and whether cardiorespiratory fitness influences…
- Conditions
- Healthy Aging, Cognitive Benefits, Cardio Respiratory Fitness, Brain Activity
- Trial name
- ExBrain (NCT07727577)
- Testing
- High-Intensity Interval Training
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Colby-Sawyer College
Subjective Cognitive Complaints
Constructing A Model of Health Promotion and Active Aging for Community-Dwelling Older Adults
Cognitive intervention for people with subjective cognitive complaints can be categorized into cognitive training, cognitive rehabilitation, psychoeducation, lifestyle intervention, etc.
- Trial name
- NCT03612167
- Testing
- cognitive intervention, nutritional group
- Where
- Taiwan
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- National Cheng Kung University
HIV-1-infection, Aging, Premature
Mental Ability Challenge Study in Adults With and Without HIV
It is estimated that by 2016, nearly 50% of HIV-positive individuals in the US will be aged 50 or older, and up to 60% of those will experience some degree of cognitive impairment as they age.
- Conditions
- HIV-1-infection, Aging, Premature, Cognitive Impairment, Memory Impairment
- Trial name
- NCT03244488
- Testing
- Scopolamine Injectable Product, Mecamylamine Pill
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Aging
The Psychobiological Effects of Participation in a One-Month Insight Meditation Retreat
The purpose of this study was to examine how participation in a 1 month intensive Insight (vipassana) Meditation retreat (a) affects biological markers of cellular aging, social affiliation, and inflammation, which are important…
- Trial name
- NCT03056105
- Testing
- Residential Insight Meditation Retreat
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Aging
Pomegranate Extract and Inflammageing
The growing ageing population has resulted in an increase in the prevalence of frailty, cognitive disorders and cardiovascular diseases, representing a major cause of disability in older adults.
- Trial name
- NCT05588479
- Testing
- Pomegranate extract, Control
- Where
- United Kingdom
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Manchester Metropolitan University
Brain Stimulation, Alzheimer Disease
Transcranial Alternating Current Stimulation (TACS) for Sleep Disturbances in Neurocognitive Disorders Due to Alzheimer's Disease
Background: Sleep disturbances are highly prevalent in ageing population and patients with age-related neurodegenerative diseases, which severely affect cognition and even lead to accumulated amyloid-β (Aβ).
- Conditions
- Brain Stimulation, Alzheimer Disease, tACS, Sleep Disturbance
- Trial name
- NCT05544201
- Testing
- High-definition transcranial current stimulation
- Where
- Hong Kong
- Volunteers
- 99 people
- Sponsor
- Chinese University of Hong Kong
Memory Problems
Brain Fitness APP for Aging With a Healthy Brain
Memory and cognitive declines are associated with normal brain aging but are also precursors to dementia, in particular the so called the pandemic of the century, Alzheimer's disease.
- Trial name
- NCT03600545
- Testing
- Brain Fitness App
- Where
- Canada
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Aging, Cognitive Change
Enhancing Cognitive Control Abilities Using Mobile Technology in a Senior Living Community
The goal of this study is to test the feasibility of launching a personalized digital health assessment and remediation program for the older adults in senior living communities based upon an initial characterization of these…
- Trial name
- ACCT (NCT04905849)
- Testing
- Adaptive Cognitive Control Trainer (ACCT), Active Control App
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Aging
Brain Stimulation and Cognitive Training in Healthy Older Adults
The aim of this study is to investigate whether a tDCS-accompanied intensive cognitive training of working memory leads to performance improvement in healthy older individuals.
- Trial name
- TrainStim (NCT03838211)
- Testing
- Anodal tDCS, Intensive cognitive training
- Where
- Germany
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University Medicine Greifswald
Aging
Neural Control of Gait & Navigation in ADRD
Brain network segregation, or independent functioning, declines with age and is associated with slower walking speed. Here, the investigators will determine the extent to which brain vestibular network segregation can be altered…
- Trial name
- NCT06501820
- Testing
- Transcranial direct current stimulation
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Florida
Perimenopause, Aging
Impact of Funcional Exercise and Supplementation in Perimenopausal Women's Health
The goal of this clinical trial is to learn whether a natural-origin nutritional supplement, combined with a functional exercise program, can improve psycho-emotional, cognitive, functional, and neuroendocrine health in…
- Trial name
- NCT07251296
- Testing
- Exercise + nutritional supplement
- Where
- Spain
- Volunteers
- 90 people
- Sponsor
- University of Valencia
Cognitive Dysfunction ( MMSE < 24 )
Effects of tDCS on Cognitive Function in Older Adults With Subjective Cognitive Decline: Randomized Sham-Controlled Trial
This randomized, double-blind, sham-controlled clinical trial evaluates the effects of transcranial direct current stimulation (tDCS) using the Sooma Oy device on cognitive function in older adults with Subjective Cognitive…
- Trial name
- TDCSCOGSCDTRIA (NCT07531888)
- Testing
- Transcranial Direct Current Stimulation
- Where
- Mexico
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universidad Autónoma del Estado de Hidalgo