Clinical trials: Cognitive Aging
VITAMIN D DEFICIENCY
An Evaluation of the Effect of Vitamin D Supplementation on the Cognitive Function of Older Subjects With Low Levels of This Vitamin
Background: Ageing is associated with an increased risk of cognitive decline and depression. Vitamin D plays an important role in many of the symptoms and conditions related to advanced age, including impaired balance, falls and…
- Trial name
- NCT02381600
- Testing
- Vitamin D
- Where
- Israel
- Volunteers
- 1 people
- Sponsor
- Meir Medical Center
Prediabetes, Healthy (Controls)
Effects of Exogenous Ketones on Cognitive Function in Older Adults With Prediabetes?
Brief Summary The goal of this clinical trial is to learn whether older adults with prediabetes, but no diagnosed cognitive impairment, show early changes in brain energy use and thinking speed compared to older adults with…
- Trial name
- NCT07546409
- Testing
- Ketone Monoester (KE)
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Aging, Healthy
Cognitive Aging and Training With Video-games
The ageing of the population will inevitably lead to a growing number of older people living alone and in need of care. Given the high cost of geriatric care, a critical research issue is exploring ways to improve or maintain…
- Trial name
- NCT02007616
- Testing
- Non-action video game training
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional de Educación a Distancia
Quality of Life, Aging
Functional Outcomes of Stay Strong Stay Healthy Program
Strength training can increase muscle mass and strength while improving bone density and reducing risk for osteoporosis and related fractures.
- Conditions
- Quality of Life, Aging, Memory Loss, Cardiovascular Diseases
- Trial name
- NCT02677363
- Testing
- Resistance Exercise
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Cancer, Cognitive Impairment
Cancer and Mild Cognitive Impairment a Patient-Caregiver Behavioral Intervention
The purpose of this study is to see whether programs that include both a patient and their spouse or a patient and family caregiver (known as a dyad) are helpful for families in which one member of the dyad has cancer and mild…
- Trial name
- NCT04826315
- Testing
- COPE +
- Where
- United States
- Sponsor
- Duke University
Cognitive Dysfunction, Alzheimer Disease
ALA-enriched Nutrition for Prevention of Cognitive Decline in APOE4 Older Adults
This randomized, double-blind, placebo-controlled pilot trial will evaluate the effects of alpha-linolenic acid (ALA) supplementation on cognitive function, blood-brain barrier integrity, and brain vascular health in older adults…
- Conditions
- Cognitive Dysfunction, Alzheimer Disease, Blood-Brain Barrier, Apolipoprotein E, Deficiency or Defect of
- Trial name
- NCT07392723
- Testing
- Alpha-Linolenic Acid (2.6 g/day)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Michal Schnaider Beeri, Ph.D.
Mild Cognitive Impairment (MCI), Ageing
Exploring and Evaluating the Impact of 'Refresh and Reconnect!'
Dementia and mild cognitive impairment are a rising concern for the ageing population in Singapore, leading to diminished quality of life and health outcomes.
- Conditions
- Mild Cognitive Impairment (MCI), Ageing, Mild Dementia, Well-being
- Trial name
- ReCognition (NCT06805578)
- Testing
- Heritage art programme
- Where
- Singapore
- Volunteers
- 108 people
- Sponsor
- Duke-NUS Graduate Medical School
Mild Cognitive Impairment
The Effects of Exercise on Synaptic Plasticity in Individuals With Mild Cognitive Impairment and in Healthy Aging.
The research is focused on ameliorating cognitive decline in aging and in individuals diagnosed with Mild Cognitive Impairment (MCI).
- Trial name
- NCT05663918
- Testing
- Self- determined Intensity Interval Training
- Where
- 6 sites in Canada
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- McMaster University
Healthy Aging
Signal Propagation and Its Relationship to Cognitive Performance in the Aging Human Brain (Focus or Spread)
In the next three decades, the world's population over 60 years old is expected to more than double its size. Even in the absence of an obvious pathology (i.e., healthy aging), advancing age is typically associated with a…
- Trial name
- NCT04361760
- Testing
- single-puls TMS
- Where
- Switzerland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Healthy People Programs
Effects of 20-week Mat-Pilates & Dual-Task Training on Strength, Balance, Cognition, and Fall Risk in Older Adults
Our aims are to evaluate the impact of 24-week combined Pilates and dual-task exercises on physical fitness, balance, cognitive function, bone density in older adults.
- Trial name
- Pilates&ST (NCT07119762)
- Testing
- Pilates sections
- Where
- Portugal
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Universidade do Porto
Cognitive Decline
Reducing the Effects of Aging on Cognition With Therapeutic Intervention of an Oral Nutrient (REACTION): A Pilot Trial
The purpose of this research is to assess the feasibility (e.g., recruitment rate, adherence rate and retention rate) of a clinical trial using virtual assessments to investigate the effect of a 6-month administration of a…
- Trial name
- NCT04147624
- Testing
- Souvenaid
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- University of Miami
Cognitive Impairment, Voice Disorders
Correlation Between Montreal Cognitive Assessment and Voice Therapy Outcomes in the Aging Treatment- Seeking Population
This study will investigate if the performance on the Montreal Cognitive Assessment (MoCA) is associated or predictive of the outcomes in voice, swallowing or upper airway therapy in the older laryngology treatment seeking…
- Conditions
- Cognitive Impairment, Voice Disorders, Voicebox Disorders, Cognitive Decline
- Trial name
- MoCA (NCT05187910)
- Testing
- Speech Therapy, Swallowing Therapy, Upper Airway Therapy
- Where
- 4 sites in United States
- Volunteers
- 57 people
- Sponsor
- University of California, San Francisco
Aging
Cognitive Effects of Transcranial Direct Current Stimulation in Older Adults
This research is being done to determine whether transcranial direct current stimulation (tDCS) can improve certain mental abilities.
- Trial name
- NCT01611103
- Testing
- transcranial direct current stimulation
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Aging
Pomegranate Extract and Inflammageing
The growing ageing population has resulted in an increase in the prevalence of frailty, cognitive disorders and cardiovascular diseases, representing a major cause of disability in older adults.
- Trial name
- NCT05588479
- Testing
- Pomegranate extract, Control
- Where
- United Kingdom
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Manchester Metropolitan University