Clinical trials: Cognitive Aids
Stroke
Helping Stroke Patients With Movement Using Photos, Videos, and Pictograms
The goal of this interventional study is to learn how different types of visual aids-photos, videos, and pictograms-help people with stroke understand and perform simple physical movements.
- Trial name
- NCT07097779
- Testing
- Visual Aids(Photos, Videos, and Pictograms)
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Jaegyeong Lee
Surgery--Complications
Cognitive Aids for the Management of Deteriorating Surgical Patients
Background and Goal of Study: Adherence to best practice management of emergencies improves through the use of cognitive aids. Aim of this study was to develop and validate cognitive aids for management of deteriorating surgical…
- Trial name
- CAMDS (NCT03812861)
- Testing
- CAMDS bundle
- Where
- Netherlands
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Acute HIV Infection, HIV CNS Involvement
Assessment of the HIV CNS Reservoir, Neurological and Neuro-cognitive Effects, and Source of Rebound HIV in CNS
This study aims to describe in depth the CNS, CNS HIV reservoir and CNS viral rebound in consenting SEARCH 019 subjects prior to, during and after the SEARCH 019 study intervention (VHM + ART or ART only), at 1) baseline, 2) end…
- Trial name
- NCT02470351
- Where
- Thailand
- Volunteers
- 9 people
- Sponsor
- SEARCH Research Foundation
Cognitive Disorders, HIV Infections
Parallel Group, Placebo-Controlled, Tolerability, Safety, and Efficacy Study of OPC-14117 in HIV Dementia
To assess the tolerability and safety of OPC-14117. To evaluate effects of OPC-14117 on cognitive function, quality of life, and activities of daily living.
- Trial name
- NCT00002148
- Testing
- OPC 14117
- Where
- 3 sites in United States
- Volunteers
- 30 people
- Sponsor
- University of Rochester
HIV Infections
A Stigma Reduction Intervention at Time of Entry Into Antenatal Care to Improve PMTCT Services in Tanzania
This study will pilot test a brief, scalable intervention called Maisha (Swahili for life), to address HIV stigma for women presenting to antenatal care in Tanzania and male partners who accompany them.
- Trial name
- Maisha (NCT03600142)
- Testing
- Mashia
- Where
- Tanzania
- Volunteers
- 1,539 people, healthy volunteers welcome
- Sponsor
- University of Utah
Social Anxiety, Sexual Risk
Sexual Confidence: CBT for Social Anxiety Disorder With HIV Risk Reduction Counselling for HIV-negative gbMSM
Given the continued high human immunodeficiency virus (HIV) prevalence rates among gay, bisexual, and other men who have sex with men (MSM) in North American cities, there is a critical need for HIV prevention interventions for…
- Conditions
- Social Anxiety, Sexual Risk, HIV
- Trial name
- SC-RCT (NCT04381559)
- Testing
- Cognitive Behavioural Therapy, Applied Relaxation
- Where
- Canada
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Toronto Metropolitan University
Hazardous Drinking, Binge Drinking
A Stage 2 Cognitive-behavioral Trial: Reduce Alcohol First in Kenya Intervention
This study will determine whether a group cognitive-behavioral therapy intervention that demonstrates preliminary evidence of reducing alcohol use among HIV-infected outpatients in western Kenya is effective when compared against…
- Conditions
- Hazardous Drinking, Binge Drinking, HIV-infected
- Trial name
- RAFIKI (NCT01503255)
- Testing
- cognitive behavioral group therapy, health education group
- Where
- Kenya
- Volunteers
- 614 people
- Sponsor
- Brown University
HIV Infections
Safety and Effectiveness of Giving CPI-1189 to HIV-Infected Patients With AIDS Dementia
The purpose of this study is to see if it is safe and effective to give CPI-1189 to patients with AIDS dementia. Advanced HIV infection can cause AIDS dementia (brain damage due to HIV leading to loss of memory and muscle…
- Trial name
- NCT00002414
- Testing
- CPI-1189
- Where
- 6 sites in United States
- Volunteers
- 60 people
- Sponsor
- Centaur Pharmaceuticals
HIV - Human Immunodeficiency Virus, Cognitive Symptoms
COMO: Cognition Study With HIV+ Patients (CTNPT 015)
The purpose of this study is to contribute evidence towards the potential to improve cognition in HIV+ individuals experiencing cognitive decline through personalized change in antiretroviral (ARV) medication.
- Trial name
- COMO (NCT02144688)
- Testing
- Change in antiretrovirals
- Where
- Canada
- Volunteers
- 19 people
- Sponsor
- Marie-Josée Brouillette
HIV (Human Immunodeficiency Virus), Sexually Transmitted Diseases
Reality Check: An HIV Risk Reduction Serial Drama
African Americans have considerably higher rates of HIV infections than do White, Hispanic, Asian, and Native Americans. African Americans accounted for 59% of all diagnoses of HIV infection among youth (13-24 years of age) in…
- Trial name
- RC (NCT03352219)
- Testing
- Reality Check, Physical Activity Attention Control
- Where
- United States
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
HIV, Stress Disorder
CBSM Intervention Via mHealth to Ameliorate HIV-related Fatigue
The purpose of this study is to create a smartphone, tablet and web-based application to help people deal with stress. Stress often increases fatigue in people with HIV infection, so successfully dealing with stress could help…
- Conditions
- HIV, Stress Disorder, Human Immunodeficiency Virus, Fatigue
- Trial name
- NCT03149094
- Testing
- CBSM-SMI, CBSM-SMI control
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Medical University of South Carolina
Cognition Disorders, HIV Infections
Safety and Effectiveness of the Selegiline "Patch" for Decreased Mental Function in HIV Patients
A decrease in mental function often occurs in patients with HIV. Antiretroviral (ARV) drugs are used to treat this but are not entirely effective. Some other therapy could play a role.
- Trial name
- NCT00013585
- Testing
- Selegiline hydrochloride
- Where
- 15 sites in United States
- Volunteers
- 127 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HIV Dementia, HIV-Associated Cognitive Motor Complex
Intranasal Insulin for the Treatment of HAND
Infection with HIV (the virus that causes AIDS) can lead to problems with brain function, such as memory, concentration, judgment, and the speed or control of hands and legs.
- Trial name
- NCT03081117
- Testing
- Insulin, intranasal
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Johns Hopkins University
HIV, Aging
The Targeted Neurocognitive Training (TNT) Study
People with HIV (PWH) often suffer from cognitive impairments known as HIV-Associated Neurocognitive Disorder (HAND). Cognitive impairments in PWH are not fully captured by traditional neurocognitive assessment; thus, we must…
- Conditions
- HIV, Aging, Cognitive Function Abnormal, Cognitive Training
- Trial name
- TNT (NCT05773430)
- Testing
- Targeted Neurocognitive Training
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
HIV-associated Cognitive Impairment, HIV Infections
Minocycline for HIV+ Cognitive Impairment in Uganda
Purpose: The purpose of the study is to assess the safety and effectiveness of minocycline, an antibiotic, in the treatment of Human immunodeficiency virus (HIV)-associated cognitive impairment in Uganda.
- Trial name
- NCT00855062
- Testing
- minocycline
- Where
- Uganda
- Volunteers
- 73 people
- Sponsor
- Johns Hopkins University
HIV Infections, Neurologic Disorders
Anakinra, A Recombinant Human IL-1 Receptor Antagonist for Neuroinflammation in HIV-1 Infection
Background: HIV can sometimes cause HIV-associated neurocognitive disorder, or HAND. HAND is HIV-associated neurocognitive disorder. It can affect memory, thinking, or concentration. It can cause mood changes.
- Trial name
- NCT02527460
- Testing
- Anakinra
- Where
- 2 sites in United States
- Volunteers
- 1 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Depression, Anxiety, Trauma
Psychoeducation, Relaxation, PrOblem Solving, Activation, Cognitive Coping Therapy for Adolescents and Youth in HIV Care
The proposed PROACT study will test the effectiveness of a mental health intervention (psychotherapy) for multiple common mental health conditions (depressive, anxiety and trauma symptoms) among adolescents and youth with HIV in…
- Conditions
- Depression, Anxiety, Trauma, HIV-1-infection
- Trial name
- PROACT (NCT06247527)
- Testing
- Psychoeducation, Relaxation, PrOblem solving, Activation, Cognitive coping Therapy, Standard of care
- Where
- Kenya
- Volunteers
- 600 people
- Sponsor
- University of Nairobi
Aging, HIV
Cognitive Behavior Therapy (CBT)-Based Group Intervention to Reduce Inflammation in Older People With HIV
In this study, the investigators will assess the feasibility and acceptability of an evidence-based CBT group intervention, developed for older people with HIV, and research methods in a pilot randomized controlled trial…
- Trial name
- CHAMP (NCT05434741)
- Testing
- Weekly Group Skills, One-time Trifold Brochure titled "HIV: 50 Years or Older"
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Massachusetts General Hospital
Human Immunodeficiency Virus (HIV), Sexually Transmitted Disease (STD)
Steering Together in a New Direction: Reducing the Risk of HIV/STD Among African American Men
African American men have by far the highest rates of HIV in the US, but there are few randomized controlled trials (RCTs) of interventions to dissuade heterosexually active African American men from engaging sexual risk…
- Trial name
- STAND (NCT02572401)
- Testing
- STAND HIV Risk Reduction Intervention, Text Messaging Intervention
- Where
- United States
- Volunteers
- 391 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Age-related Hearing Loss, Hearing Loss, Sensorineural
A Prospective Cohort Study On Change of Cognitive Function In Aged-related Hearing Loss With Hearing Aids
Background: Deafness is one of the nine potentially modifiable risk factors for dementia simulated by the Lancet dementia Prevention, intervention and Care Committee in 2017.
- Conditions
- Age-related Hearing Loss, Hearing Loss, Sensorineural, Hearing Aid, Cognitive Function Abnormal
- Trial name
- NCT05694039
- Testing
- Hearing Aids
- Where
- China
- Volunteers
- 388 people, healthy volunteers welcome
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University