Clinical trials: Cognitive Aids
Frailty, Sarcopenia
Comprehensive Geriatric Assessment in Adults Aged 40 Years and Older Living With HIV
People living with HIV are experiencing longer life expectancy due to effective antiretroviral therapy; however, they may develop age-related conditions earlier than the general population.
- Trial name
- HIV-AGE40 (NCT07453303)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital
HIV Infections
Integrase and Maraviroc Intensification in Neurocognitive Dysfunction (InMIND)
People infected with HIV often have cognitive dysfunction even if they are on antiretroviral therapy (ART) and have undetectable viral loads.
- Trial name
- NCT02519777
- Testing
- Dolutegravir (DTG), Maraviroc (MVC)
- Where
- 30 sites in United States, Brazil and 3 more
- Volunteers
- 191 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Hiv, Opioid Use Disorder
Optimizing Evidence-based HIV Prevention Targeting People Who Inject Drugs on PrEP
The investigators will conduct an optimization trial among N=256 PWID newly started on medication for opioid use disorder and Pre-Exposure Prophylaxis (PrEP) to assess the performance of four intervention components (Attention…
- Trial name
- MOST (NCT05669534)
- Testing
- community-friendly health recovery program, Pre-Exposure Prophylaxis and Post-Exposure Prophylaxis
- Where
- United States
- Volunteers
- 256 people
- Sponsor
- University of Connecticut
Human Immunodeficiency Virus, Smoking Cessation
Effectiveness of an Integrated Treatment to Address Smoking Cessation and Anxiety/ Depression in People Living With HIV
Smokers living with HIV represent a major health disparity population in the United States and the world more generally. Major contributing factors to the maintenance and relapse of smoking among smokers living with HIV include…
- Conditions
- Human Immunodeficiency Virus, Smoking Cessation, Smoking, Cigarette, Smoking
- Trial name
- NCT03904186
- Testing
- QUIT, Time-Matched Control (TM)
- Where
- 3 sites in United States
- Volunteers
- 131 people
- Sponsor
- Massachusetts General Hospital
Depressive Symptoms, HIV Infections
Depression and ART Adherence in HIV+ Latinos
The current HIV treatment adherence project was designed to adapt culturally and then pilot test an empirically supported cognitive-behavioral therapy program for adherence and symptoms of depression (CBT-AD)with HIV+ Latinos…
- Trial name
- NCT01411839
- Testing
- Cognitive-Behavioral Therapy (CBT-AD)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Washington
Cocaine Use Disorders, HIV
Project IMPACT: Improving Memory Performance by Applying Cognitive Training
The purpose of this study is to examine the effects of a cognitive training program in persons with Human Immunodeficiency Virus (HIV) infection who have used cocaine.
- Trial name
- NCT02909101
- Testing
- Active Cognitive Training (ACT), Control Training (CON)
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Duke University
HIV Infections, Depression
Pilot Testing Into the Feasibility of the Developed Cognitive Behavioral Therapy Intervention
This pilot feasibility randomized controlled trial will test a culturally adapted cognitive behavioral therapy (Ca-CBT) intervention for depression and anxiety among people living with HIV (PLHIV) in Peshawar, Pakistan.
- Conditions
- HIV Infections, Depression, Anxiety Disorders
- Trial name
- CHERISH (NCT07235852)
- Testing
- Culturally Adapted Cognitive Behavioral Therapy (Ca-CBT), Treatment as Usual (TAU)
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- Khyber Medical University Peshawar
HIV Infections, Depression
HIV, Computerized Depression Therapy & Cognition
Among people with HIV, the severity of depressive symptoms has repeatedly been associated with the presence of self-reported cognitive difficulties, even in the absence of impairment on neuropsychological testing.
- Conditions
- HIV Infections, Depression, CBT
- Trial name
- NCT03275571
- Testing
- cCBT intervention
- Where
- Canada
- Volunteers
- 8 people
- Sponsor
- McGill University
HIV Infections, Depression
The Influence of GINkGo Biloba on the Pharmacokinetics of the UGT Substrate raltEgraviR (GINGER)
The objective of this study is to evaluate the effect of ginkgo biloba (steady state) on the pharmacokinetics of a single dose of the UGT-substrate raltegravir. Furthermore the safety profile of the combination is studied.
- Conditions
- HIV Infections, Depression, Mild Cognitive Impairment
- Trial name
- GINGER (NCT01246804)
- Testing
- raltegravir single dose, ginkgo biloba multiple dose
- Where
- Netherlands
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
HIV Infections, Episodic Substance Use
Reducing HIV Risk Among Episodic Substance Using Men Who Have Sex With Men (SUMSM)
The purpose of this study is to determine if persons randomized to receive adapted Personalized Cognitive Risk-reduction Counseling (PCC) will report greater reductions in unprotected anal sex behavior compared with persons who…
- Trial name
- NCT01279044
- Testing
- Adapted Personalized Cognitive Risk-reduction Counseling intervention (PCC), Standard HIV testing with information only
- Where
- United States
- Volunteers
- 385 people, healthy volunteers welcome
- Sponsor
- San Francisco Department of Public Health
HIV Infections
Pre-HIV Test Counseling Intervention to Reduce HIV Infection Risk Behavior in Men Who Are Not HIV Infected
This study will evaluate the effectiveness of a single specialized pre-test counseling session in reducing HIV infection risk behavior in men who are not HIV infected.
- Trial name
- NCT00218699
- Testing
- Cognitive-Behavioral Intervention
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Age-related Macular Degeneration, Dementia
Words on the Brain: Can Reading Rehabilitation for Age-Related Vision Impairment Improve Cognitive Functioning?
Age-related vision impairment and dementia both become more prevalent with increasing age. Research into the mechanisms of these conditions has proposed that some of their causes (e.g., macular degeneration/glaucoma and…
- Conditions
- Age-related Macular Degeneration, Dementia, Low Vision, Low Vision Aids
- Trial name
- WOTB (NCT04276610)
- Testing
- Low Vision Reading Rehabilitation
- Where
- 2 sites in Canada
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Université de Montréal
HIV, Depression
IMPAACT 2002: Cognitive Behavioral Therapy and Medication Management for Treatment of Depression in US Youth With HIV
IMPAACT 2002 is a prospective, multi-site, two-arm, cluster-randomized study to evaluate whether a health and wellness Cognitive Behavioral Therapy and Medication Management (COMB-R) intervention for depression demonstrates…
- Trial name
- NCT02939131
- Testing
- Health and Wellness Combined Cognitive Behavioral Therapy and a Medication Management Algorithm, Enhanced Standard of Care
- Where
- 13 sites in United States
- Volunteers
- 156 people
- Sponsor
- International Maternal Pediatric Adolescent AIDS Clinical Trials Group
Efavirenz, Child Behavior
Neuropsychiatric Side Effects of Efavirenz in Children Living With HIV
Efavirenz is among the preferred antiretroviral drugs for HIV-infected children. Increasing evidence shows that central nervous system side-effects in adults are more common than previously thought.
- Conditions
- Efavirenz, Child Behavior, Cognitive Symptom, Medication Adherence
- Trial name
- NCT03227653
- Testing
- Efavirenz, Nevirapine, Lopinavir-Ritonavir Drug Combination
- Where
- 6 sites in Tanzania
- Volunteers
- 144 people
- Sponsor
- Radboud University Medical Center
Drug Abuse, HIV Infections
Neurobehavioral Model of HIV in Injection Drug Users
The purpose of this R01 study is to evaluate the association between neuropsychological executive dysfunction and HIV infection among young injection and non-injection drug users.
- Trial name
- NCT00198861
- Testing
- Injection and Non-Injection Drug Users
- Where
- United States
- Volunteers
- 836 people
- Sponsor
- The City College of New York
HIV Infections
Integrated Treatment of Marijuana Abuse for HIV+ Youth
This is an exploratory study that will adapt and test a combined cognitive behavioral treatment and contingency management intervention for alcohol and/or marijuana abuse for use in HIV-infected adolescents.
- Trial name
- NCT00683488
- Testing
- Focus Group, First Intervention Trial, Intervention Trial 2
- Where
- 3 sites in United States
- Volunteers
- 46 people
- Sponsor
- University of North Carolina, Chapel Hill
Depression
The Effect of Combination Mindfulness Spiritual-Based Cognitive Therapy Plus Hypnosis in HIV Patients With Depression
HIV/AIDS patients are at risk for depression, a multifactorial disorder with signs and symptoms that affect the cognitive, affective, behavioral, and somatic areas. This study used Randomized Controlled Clinical Trials (RCT).
- Trial name
- NCT05659472
- Testing
- Combination mindfulness spiritual-based cognitive therapy plus hypnosis, Mindfulness-based cognitive therapy
- Where
- Indonesia
- Volunteers
- 62 people
- Sponsor
- Health Technology Institute of Cendekia Utama Kudus
Poor Quality Sleep, HIV Infections
Neurofeedback Training (NFT) on Sleep Quality and Cognitive Function Performance Among HIV-infected Persons
The purpose of this study is to evaluate the effects of NFT on sleep quality and cognitive-behavioral performance among HIV-infected patients, to use it as a reference for the construction of NFT as a clinical empirical treatment…
- Trial name
- NCT05155787
- Testing
- Neurofeedback
- Where
- Taiwan
- Volunteers
- 13 people
- Sponsor
- National Cheng-Kung University Hospital
Depression, HIV Infections
Telephone Based Cognitive Behavioral Therapy for HIV Related Depression
The purpose of this study is to evaluate the effectiveness of a telephone-based, cognitive behavioral therapy intervention in the treatment of depression in adults diagnosed with HIV.
- Trial name
- NCT01055158
- Testing
- Telephone-based CBT, Enhanced Usual Care
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- University of Maryland, Baltimore
Cognitive Change
Working Memory Training for People Aging With HIV
The present study investigates the feasibility of working memory training in people aging with HIV (PAWHIV). In a cross-over design this stage 1 feasibility trial, will evaluate acceptability, and estimate possible effect sizes…
- Trial name
- NCT06699927
- Testing
- Span
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Northeastern University