Clinical trials: Cognitive Aids
Basic Life Support (Simulation)
Supporting Tools and Cognitive Aids for BLS
Various studies have shown that rapid and correctly performed cardiopulmonary resuscitation (CPR) significantly increases the survival rate after cardiac arrest.
- Trial name
- NCT06601946
- Testing
- BLS Paper Based Cognitive App, First Aid App, Corpatch App
- Where
- Austria
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Alzheimer Disease, HIV
F 18 T807 PET (Positron Emission Tomograph )Scan for HIV Infected & Uninfected
This project will collect quantitative pilot data that will allow the characterization of uptake and binding of 18F-AV-1451 (also known as F 18 T807, also known as T807, also known as…
- Trial name
- NCT03279523
- Testing
- F 18 T807
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tammie L. S. Benzinger, MD, PhD
HIV Infections
HIV Prevention in Haitian American Adolescents
There has not been a great deal of research involving Haitian American adolescents and HIV risk reduction. The purpose of the study is to learn better ways to teach teenagers about living healthy by educating these children about…
- Trial name
- NCT00494273
- Testing
- Cognitive Behavioral and Standard Care with Healthy Living
- Where
- United States
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
AIDS Dementia Complex, HIV-1-Associated Cognitive Motor Complex
Effect of Cenicriviroc on HIV Neurocognitive Impairment
The study hypothesis is that cenicriviroc will improve cognition in HIV infected individuals with cognitive impairment. The investigators will study the effect of cenicriviroc on cognition in 24 subjects over a 24 week period.
- Conditions
- AIDS Dementia Complex, HIV-1-Associated Cognitive Motor Complex, Human Immunodeficiency Virus
- Trial name
- NCT02128828
- Testing
- cenicriviroc
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Hawaii
HIV/AIDS, Violence
Effectiveness of Transdiagnostic Cognitive Behavioral Therapy for Improving HIV Treatment Outcomes in South Africa
This study will evaluate the impact of the Common Elements Treatment Approach (CETA), an evidence-based intervention comprised of cognitive-behavioral therapy elements, at improving HIV treatment outcomes among women with HIV who…
- Trial name
- CETA (NCT04242992)
- Testing
- CETA, Short Message Service (SMS) text reminders
- Where
- South Africa
- Volunteers
- 399 people, healthy volunteers welcome
- Sponsor
- Boston University
HIV, Aging
A Novel Neurorehabilitation Approach for Cognitive Aging With HIV
The goal of this study is to conduct a small, self-contained project to test the hypothesis that tDCS will augment SOP cognitive remediation therapy (CRT) in older HIV+ adults.
- Trial name
- HtDCS (NCT02391311)
- Testing
- transcranial direct current stimulation (tDCS)
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- University of Alabama at Birmingham
HIV
Adaptation and Evaluation of an Intersectional Stigma Reduction Intervention to Increase HIV Care Engagement Among Women Who Use Drugs
The goal of this study is to test whether a program reduce stigma will help women living HIV remain in HIV care.
- Trial name
- Light Inside (NCT07751978)
- Testing
- Light Inside, standard of care
- Where
- Ukraine
- Volunteers
- 100 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
HIV/AIDS
Translation of Basic Research in Cognitive Science to HIV Risk
A randomized trial was conducted at drug diversion educational programs with a sample of 343 adult drug offenders who volunteered for the study.
- Trial name
- NCT03175250
- Testing
- Health Education, Action Plan, Memory Practice
- Volunteers
- 343 people, healthy volunteers welcome
- Sponsor
- Claremont Graduate University
Quality of Life
Impact of Schemas, Cognitive Emotion Regulation on Quality of Life of HIV Patients: Assessing Outcomes of CBT
The present study has investigated the impact of schemas, cognitive emotion regulation and social connectedness on the Quality of life of HIV patients in South Punjab region, Pakistan.
- Trial name
- Step-II (NCT06123078)
- Testing
- CaCBT
- Where
- 2 sites in Pakistan
- Volunteers
- 40 people
- Sponsor
- Islamia University of Bahawalpur
HIV Infections, Central Nervous System Diseases
Clinical Trial of Brain-Penetrating HIV Drugs to Prevent Cognitive Impairment in China
This primary aim of the project is to determine the association between antiretroviral therapy that better distributes into the central nervous system and prevention of HIV-associated neurocognitive impairment.
- Conditions
- HIV Infections, Central Nervous System Diseases, Dementia
- Trial name
- NCT01340950
- Testing
- zidovudine-lamivudine-nevirapine, tenofovir-lamivudine-efavirenz
- Where
- 2 sites in China
- Volunteers
- 250 people
- Sponsor
- University of California, San Diego
HIV-1-Associated Cognitive Motor Complex
The Prevalence of Neurocognitive Disorder in a Primary Care-based HIV Cohort Compared to a HIV-negative Control Cohort -
To determine the prevalence of HIV associated Neurological Disorder (HAND) in a population of HIV positive patients within a primary care setting compared with the HIV negative population.
- Trial name
- CNS HAND (NCT01434563)
- Volunteers
- 326 people, healthy volunteers welcome
- Sponsor
- Holdsworth House Medical Practice
The Study Was Designed to Develop a Cognitive Behavioral Approach to Treating Methamphetamine Abuse in HIV Primary Care Settings
Behavioral Therapy Development for Methamphetamine Abusers
The purpose of this study is...to assess whether placing a substance abuse intervention for HIV+ methamphetamine users within an HIV medical care setting improves rates of follow-up on referral to treatment by primary care…
- Trial name
- NCT00249678
- Testing
- Behavior Therapy
- Where
- 3 sites in United States
- Sponsor
- University of California, Los Angeles
Aging, Cognitive Function Abnormal
Executive Functioning Training Study
Cognitive aging in people with HIV (PWH) is of increasing concern for several reasons: 1) between 52%-59% of PWH experience cognitive impairment known as HIV-Associated Neurocognitive Disorder (HAND) which impacts everyday…
- Conditions
- Aging, Cognitive Function Abnormal, Cognitive Performance, Cognitive Training
- Trial name
- EFT (NCT05598047)
- Testing
- Executive Functioning Training
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
HIV Associated Cognitive Motor Complex
Effect of Galantamine on Inflammation and Cognition
This study tests whether galantamine (GAL) reduces HIV-related inflammation and cognitive deficits. In this double-blind placebo-controlled crossover study, HIV-infected individuals (N=120; 60 smokers and 60 non-smokers) will be…
- Trial name
- CHI (NCT03384784)
- Testing
- Galantamine
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- University of Pennsylvania
Memory Impairment, HIV/AIDS
COGnitive ImpairmenT in Older HIV-infected Patients ≥ 65 Years Old
Despite combined antiretroviral therapy (cART), milder forms of HIV-associated neurocognitive disorders (HAND) persist in 20-50% of persons living with HIV (PLHIV).
- Conditions
- Memory Impairment, HIV/AIDS, Cognitive Impairment
- Trial name
- COGITO (NCT03268109)
- Testing
- assessment of cognitive impairment
- Where
- France
- Volunteers
- 281 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Insomnia
Digital Behavioral Therapy for Sleep Problems
Insomnia is very common, especially in HIV population (up to 73%), and contributes to the development of other conditions such as depression, dementia, inflammation, obesity, and heart diseases.
- Trial name
- dBTS (NCT04308499)
- Testing
- Digital cognitive-behavioral therapy for insomnia (dCBTI), Sleep hygiene education (SHE)
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of California, Los Angeles
Alzheimer Disease, Presbycusis
Clinical Trial on Alzheimer Disease, Presbycusis and Hearing Aids
This is a 12-months' randomized clinical trial that aims at studying the benefit of bilateral hearing aids in hearing impaired patients suffering from a slight to moderate stage Alzheimer disease.
- Trial name
- NCT00488007
- Testing
- Hearing aids used : PHONAK Savia and Valeo
- Where
- France
- Volunteers
- 51 people
- Sponsor
- Hospices Civils de Lyon
Nicotine Dependence, Symptoms of Anxiety
Integrated Treatment for Smoking Cessation & Anxiety in People With HIV
During the 1-year formative phase of a study to develop an integrated treatment for quitting smoking for anxiety-vulnerable HIV+ smokers.
- Conditions
- Nicotine Dependence, Symptoms of Anxiety, HIV
- Trial name
- Project Quit (NCT01393301)
- Testing
- Integrated cognitive-behavioral therapy for smoking cessation and anxiety, Control
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Massachusetts General Hospital
HIV Infections
Management by Individual Cognitive Remediation of Cognitive Disorders of HIV Infected Patients
Despite sustained inhibition of viral replication in plasma undergoing treatment, nearly 30% of HIV-infected patients have HIV-related cognitive impairment. To date, no therapeutic strategy has demonstrated clinical efficacy.
- Trial name
- COGSTIM2 (NCT03639818)
- Testing
- individual sessions of cognitive remediation
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
HIV-1-infection
IMPAACT 2015 - Evaluation of the HIV-1 Reservoir in the Central Nervous System of Perinatally-Infected Youth and Young Adults With Cognitive Impairment
IMPAACT 2015 is a cross-sectional, exploratory study that will investigate the central nervous system (CNS) reservoir in perinatally HIV-infected adolescents and young adults on effective antiretroviral therapy with…
- Trial name
- NCT03416790
- Where
- 12 sites in United States, Puerto Rico
- Volunteers
- 24 people
- Sponsor
- International Maternal Pediatric Adolescent AIDS Clinical Trials Group