Clinical trials: Cognitive Aids, open to volunteers
Depression, Anxiety, Trauma
Psychoeducation, Relaxation, PrOblem Solving, Activation, Cognitive Coping Therapy for Adolescents and Youth in HIV Care
The proposed PROACT study will test the effectiveness of a mental health intervention (psychotherapy) for multiple common mental health conditions (depressive, anxiety and trauma symptoms) among adolescents and youth with HIV in…
- Conditions
- Depression, Anxiety, Trauma, HIV-1-infection
- Trial name
- PROACT (NCT06247527)
- Testing
- Psychoeducation, Relaxation, PrOblem solving, Activation, Cognitive coping Therapy, Standard of care
- Where
- Kenya
- Volunteers
- 600 people
- Sponsor
- University of Nairobi
Age-related Hearing Loss, Hearing Loss, Sensorineural
A Prospective Cohort Study On Change of Cognitive Function In Aged-related Hearing Loss With Hearing Aids
Background: Deafness is one of the nine potentially modifiable risk factors for dementia simulated by the Lancet dementia Prevention, intervention and Care Committee in 2017.
- Conditions
- Age-related Hearing Loss, Hearing Loss, Sensorineural, Hearing Aid, Cognitive Function Abnormal
- Trial name
- NCT05694039
- Testing
- Hearing Aids
- Where
- China
- Volunteers
- 388 people, healthy volunteers welcome
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Cognition, Gut Microbiome
The Path Study: Cognitive and Inflammation Targeted Gut-brain Interventions in Alcohol; Probiotics, Alcohol, Transcutaneous Vagus Nerve Stimulation, and HIV Study
This project uses a hybrid trial design to evaluate two biomedical interventions targeting the gut-brain axis. One intervention is portable Transcutaneous Vagus Nerve Stimulator, tVNS, that is hypothesized to stimulate the…
- Trial name
- NCT05090267
- Testing
- Probiotic Supplement, Transcutaneous Vagal Nerve Stimulation (tVNS)
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Florida
HIV, Arterial Stiffness
High-Intensity Exercise to Combat Vascular and Cognitive Dysfunction in Adults With HIV
This is a single site, randomized exercise trial with individuals at least 50 years of age living with HIV who experience suboptimal cognition.
- Conditions
- HIV, Arterial Stiffness, Cognitive Dysfunction
- Trial name
- NCT05965518
- Testing
- High-Intensity Interval Training, Continuous Moderate Exercise
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Alabama at Birmingham
Frailty, Sarcopenia
Comprehensive Geriatric Assessment in Adults Aged 40 Years and Older Living With HIV
People living with HIV are experiencing longer life expectancy due to effective antiretroviral therapy; however, they may develop age-related conditions earlier than the general population.
- Trial name
- HIV-AGE40 (NCT07453303)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital
Hiv, Opioid Use Disorder
Optimizing Evidence-based HIV Prevention Targeting People Who Inject Drugs on PrEP
The investigators will conduct an optimization trial among N=256 PWID newly started on medication for opioid use disorder and Pre-Exposure Prophylaxis (PrEP) to assess the performance of four intervention components (Attention…
- Trial name
- MOST (NCT05669534)
- Testing
- community-friendly health recovery program, Pre-Exposure Prophylaxis and Post-Exposure Prophylaxis
- Where
- United States
- Volunteers
- 256 people
- Sponsor
- University of Connecticut
Insomnia, HIV Infections
Telenursing-Based Sleep Coaching for Adults Living With HIV With Insomnia Symptoms
Insomnia is common among people living with HIV and is linked to fatigue and lower quality of life. Cognitive behavioural therapy for insomnia (CBT-I) is the recommended first-line treatment, but access is limited in Indonesia.
- Trial name
- NCT07892534
- Testing
- Telenursing-based sleep coaching
- Where
- Indonesia
- Volunteers
- 50 people
- Sponsor
- Universitas Indonesia
Last Year Medical Student
Use of Cognitive Aid Methods in the Management of Status Epilepticus
This study aims to evaluate whether cognitive aids improve the management performance of sixth-year Emergency Medicine interns during simulated status epilepticus scenarios.
- Trial name
- NCT07603843
- Testing
- Management of status epilepticus with paper cognitive aids, Management of status epilepticus with digital cognitive aids, Management of status epilepticus with no cognitive aid
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Ankara University
Hearing Loss, Mild Cognitive Impairment
OTC Hearing Aid and MCI
The goal of this study is to better understand if, in patients with mild to moderate hearing loss who are also experiencing mild cognitive impairment (MCI) or Alzheimer's disease and related dementias (ADRD), Over-the-Counter…
- Conditions
- Hearing Loss, Mild Cognitive Impairment, Alzheimer Disease and Related Dementias (ADRD)
- Trial name
- NCT06112860
- Testing
- Over the counter hearing aid, Communication Strategies Information/Counseling
- Where
- 3 sites in United States
- Volunteers
- 50 people
- Sponsor
- Northwestern University
HIV -1 Infection, Mental Health Issue
Integrating iSYV Within HIV Clinical Care for Youth Living With HIV in Tanzania
Youth living with HIV (YLWH) experience mental health (MH) challenges that compromise their HIV care. Though the MH gap is well described, MH service delivery to YLWH is rare, especially in low resource settings.
- Trial name
- NCT07621510
- Testing
- iSYV (integrated Sauti ya Vijana; The Voice of Youth), mHealth, eSOC
- Where
- Tanzania
- Volunteers
- 5,000 people
- Sponsor
- Duke University
HIV, PrEP
The ACT-PrEP Study
AIM: To evaluate the integration of point-of-care etiological STI testing, cognitive behavioral counselling (CBC), and sexual partner engagement strategies to improve STI management, PrEP uptake and 3-month PrEP persistence among…
- Conditions
- HIV, PrEP, Acceptability, Appropriateness
- Trial name
- NCT07867990
- Testing
- POC STI testing, CBC, and partner self-testing to improve PrEP uptake and persistence among pregnant and postpartum women., Standard of Care
- Volunteers
- 120 people
- Sponsor
- University of California, Los Angeles
HIV Infections, Cognitive Impairment
Effect of High-Intensity Exercise to Attenuate Cognitive Function Limitations and Train Exercise Habits in Older People Living With HIV
People aging with HIV are at higher risk for Alzheimer's disease and related dementias, and although physical activity is a promising target to mitigate such risk, this population engages in low levels of physical activity.
- Trial name
- HEALTH-COG (NCT06013579)
- Testing
- Phase 1 Gym Exercise HIIT, Phase 1 Gym Exercise CME, Phase 2 Home Exercise Coaching Text Messages
- Where
- 3 sites in United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
PrEP Adherence, Methamphetamine Use Disorder
CHAMPION: Combining HIV And Meth Prevention and Treatment Interventions Optimized for HIV-Negative MSM
The goal of this randomized controlled trial is to pilot test new mobile health (mHealth) interventions to improve PrEP adherence among HIV-negative men who have sex with men (MSM) with mild to moderate methamphetamine use…
- Conditions
- PrEP Adherence, Methamphetamine Use Disorder, HIV
- Trial name
- CHAMPION (NCT07213258)
- Testing
- CHAMPION Intervention, Delayed CHAMPION Package
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of California, San Diego
HIV, Depression in Adults
The Effects of Cognitive Behavioral Therapy on Insulin Resistance in People With HIV
The goal of this clinical trial is to learn if depression treatment improves insulin resistance, or how the body uses insulin to lower blood sugar, in people with HIV on HIV treatment.
- Conditions
- HIV, Depression in Adults, Insulin Resistance, Cognitive Behavior Therapy
- Trial name
- NCT07226128
- Testing
- Internet cognitive behavioral therapy (iCBT-D), Active Control (AC)
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Indiana University
HIV
Adaptation and Evaluation of an Intersectional Stigma Reduction Intervention to Increase HIV Care Engagement Among Women Who Use Drugs
The goal of this study is to test whether a program reduce stigma will help women living HIV remain in HIV care.
- Trial name
- Light Inside (NCT07751978)
- Testing
- Light Inside, standard of care
- Where
- Ukraine
- Volunteers
- 100 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Communication Aids for Disabled, Communication Disorders
Outcomes of ICT Assistive Technology in RehabiliTAtIoN Pathways
The study aims to improve the quality of prosthetic intervention and verify the adequacy of assistive devices, and measurement outcomes.
- Conditions
- Communication Aids for Disabled, Communication Disorders, Motor Disorders, Cognitive Disorder
- Trial name
- ATTAIN (NCT06546813)
- Testing
- scales and questionnaire administration
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS