Clinical trials: Cognitive Behavior Treatment
Depression
Thrive Care: Internet CBT for Depression
This project will study the effectiveness of computerized cognitive behavioral therapy (CBT) in reducing depression symptoms. The design is a two-arm randomized controlled trial comparing (i) control arm, which is treatment as…
- Trial name
- NCT03079895
- Testing
- Thrive
- Where
- United States
- Volunteers
- 304 people
- Sponsor
- Kaiser Permanente
Schizophrenia, Hallucinations
Evaluation of Internet-based Cognitive Behavioral Self-help Treatments for People With Psychosis
Schizophrenia is a severe mental disorder which is accompanied by an enormous individual and societal burden. Despite established efficacy of cognitive behavioral therapy for psychosis (CBTp), its dissemination into routine…
- Conditions
- Schizophrenia, Hallucinations, Persecutory Delusion
- Trial name
- EviBaS (NCT02974400)
- Testing
- Internet-based, CBT-oriented, guided self-help
- Where
- 2 sites in Germany, Switzerland
- Volunteers
- 101 people
- Sponsor
- University of Bern
Autism Spectrum Disorder, Sleep Disturbance
Internet-delivered Cognitive Behaviour Therapy for Sleep Problems in ASD
This trial investigates the behavioural effects of Internet-based Cognitive behaviour therapy for insomnia (CBT-I) in adolescents with autism spectrum disorder with sleep problems. This is a randomised controlled trial.
- Conditions
- Autism Spectrum Disorder, Sleep Disturbance, Insomnia
- Trial name
- NCT03624400
- Testing
- Internet-based CBT-I, Internet-based psychoeducation
- Where
- Sweden
- Volunteers
- 240 people
- Sponsor
- Stockholm University
Alcohol Use Disorder (AUD), PTSD
Recovery Through Inhibitory Learning, Self-Efficacy Building, Problem Solving, and Community Building
This is a two-part study to develop and test a brief, virtual therapy program for lesbian, gay, bisexual, transgender, and queer (LGBTQ+) people who have experienced trauma and use alcohol.
- Trial name
- RISE (NCT07217795)
- Testing
- CBT + expressive writing, Wait-List Control
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Rhode Island
Body Dysmorphic Disorder, Obsessive-Compulsive Spectrum Disorder
Cognitive-Behavioral Therapy and Supportive Psychotherapy for Body Dysmorphic Disorder
The purpose of this study is to learn more about two different types of psychotherapy to help individuals who have body dysmorphic disorder (BDD).
- Conditions
- Body Dysmorphic Disorder, Obsessive-Compulsive Spectrum Disorder, Anxiety Disorders, Somatoform Disorders
- Trial name
- NCT01453439
- Testing
- Cognitive Behavioral Therapy, Supportive Psychotherapy
- Where
- 2 sites in United States
- Volunteers
- 120 people
- Sponsor
- Massachusetts General Hospital
Schizophrenia, Schizoaffective Disorder
A Study of Varenicline for Prevention of Relapse to Smoking in Patients With Schizophrenia or Bipolar Disorder
Varenicline (Chantix) is a smoking cessation treatment that was approved in 2006 by the FDA for treatment of nicotine dependence and may be particularly beneficial in smokers with schizophrenia or bipolar disorder.
- Conditions
- Schizophrenia, Schizoaffective Disorder, Bipolar Disorder, Smoking
- Trial name
- SCRP (NCT00621777)
- Testing
- Varenicline
- Where
- 10 sites in United States
- Volunteers
- 247 people
- Sponsor
- Massachusetts General Hospital
Panic Disorder
Physical Activity and Cognitive Behavioural Therapy in Panic Disorder
Physical activity (treadmill) supports the effect of cognitive behavioural therapy in patients with panic disorder with/without agoraphobia
- Trial name
- NCT01788800
- Testing
- Cognitive Behavioural Therapy (CBT)
- Volunteers
- 46 people
- Sponsor
- Charite University, Berlin, Germany
Post-Traumatic Stress Disorder
RCT of CBT Combined With D-Cycloserine for Treating PTSD
The purpose of this study is to investigate if the effectiveness of cognitive-behavioral therapy for post-traumatic stress disorder can be increased by combining it with D-cycloserine (TCC/D-cycloserine) by comparing with a…
- Trial name
- NCT00452231
- Testing
- D-cycloserine, Cognitive-Behavioral Therapy
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Université de Montréal
Major Depressive Disorder
Software Treatments for Actively Reducing Severity of Cognitive Deficits in MDD (STARS-MDD)
The purpose of this study is to evaluate the effects of videogame-like digital therapies as adjunct therapy to antidepressant medications on cognitive deficits associated with major depressive disorder.
- Trial name
- NCT03310281
- Testing
- HOLD: Videogame
- Where
- 4 sites in United States
- Volunteers
- 84 people
- Sponsor
- Akili Interactive Labs, Inc.
Substance Abuse
Positive Effects of Laser Acupuncture in Methamphetamine Users Undergoing Group Cognitive Behavioral Therapy: A Pilot Study
Methamphetamine (MA) addiction has become a crucial public health issue due to its adverse effects. Acupuncture has been used for drug detoxification for many years. However, some disadvantages are not be suitable for MA users.
- Trial name
- NCT04789772
- Testing
- Laser acupuncture
- Where
- 2 sites in Taiwan
- Volunteers
- 15 people
- Sponsor
- Chang Gung Memorial Hospital
Depressive Disorder in Mothers
Treatment of Depression in Mothers in Home Visitation
This study develops and contrasts In-Home Cognitive Behavioral Therapy (IH-CBT), an adapted evidence-based treatment for depressed mothers participating in home visitation, with typical home visitation in which treatment may be…
- Trial name
- MIDIS (NCT01221701)
- Testing
- In-Home Cognitive Behavioral Psychology
- Where
- United States
- Volunteers
- 93 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Social Phobia
A Comparison Between Internet Therapy and Group Therapy for Social Phobia - A Trial Using Cognitive Behavioural Therapy
Social phobia is one of the most prevalent anxiety disorders in the western world. Cognitive behavioural therapy (CBT) is the psychological treatment that has the largest empirical support.
- Trial name
- IS1 (NCT00564967)
- Testing
- CBT via the Internet, CBT group therapy
- Where
- Sweden
- Volunteers
- 128 people
- Sponsor
- Karolinska Institutet
Dementia, Mild, Mild Cognitive Impairment (MCI)
The "Let's Talk Tech" Tool to Support Decision Making About Technology Use
The goal of this research is to educate people about different technologies to support care at home when someone is experiencing memory difficulties.
- Trial name
- NCT06817122
- Testing
- Let's Talk Tech
- Where
- United States
- Volunteers
- 222 people
- Sponsor
- University of Washington
Depression Moderate, Depression Mild
A Pilot Study Comparing the Efficacy of Traditional Buddhist Mindfulness Training Versus Secular Mindfulness-based Cognitive Therapy for Patients Having Residual Depressive Symptoms
This interventional study is conducted with the goal of comparing the efficacy of traditional Buddhist mindfulness training versus secular mindfulness based cognitive therapy among patients with depressive disorders.
- Trial name
- NCT06456931
- Testing
- Traditional Buddhist mindfulness, secular mindfulness based cognitive therapy
- Where
- Sri Lanka
- Volunteers
- 60 people
- Sponsor
- Anuradha Baminiwatta
Spine Surgery
SpinePal Open Pilot
SpinePal is a self-guided digital intervention developed for patients undergoing spine surgery. The goal of this study is to learn if SpinePal is acceptable to people undergoing spine surgery.
- Trial name
- NCT07737912
- Testing
- SpinePal
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Trustees of Dartmouth College
Irritable Bowel Syndrome
Cognitive Behavioral Therapy With Our Without Exposure Therapy for Irritable Bowel Syndrome
Patients with a diagnosis of irritable bowel syndrome (IBS) are recruited by self-referral. They are randomized to two 10 weeks of internet-delivered cognitive behavioral programs.
- Trial name
- NCT01529567
- Testing
- Cognitive Behavioral Therapy without exposure, Cognitive Behavioral Therapy with exposure
- Volunteers
- 311 people
- Sponsor
- Karolinska Institutet
Anxiety Disorders, Depression
Evidence-Based Psychological Treatment for Emotional Disorders Attended in Dominican Primary Care Units (PsicAP)
Emotional disorders affect millions of people all over the world. Thousands of Dominicans suffer from depression, anxiety, and other emotional disorders that have negative impact on their lives.
- Conditions
- Anxiety Disorders, Depression, Somatic Disorders, Emotional Disorder
- Trial name
- PsicAP (NCT04642092)
- Testing
- PsicAP protocol, Conventional treatment
- Where
- 4 sites in Dominican Republic
- Volunteers
- 300 people
- Sponsor
- Pontificia Universidad Catolica Madre y Maestra
Pedophilia
ReDirection / Self-Guided ICBT to Reduce the Risk of Child Sexual Abuse Material (CSAM) Use
The creation and distribution of child sexual abuse material (CSAM) is a large-scale global problem. CSAM is sometimes referred to as child pornography.
- Trial name
- NCT06778044
- Testing
- ReDirection 1.0, ReDirection 2.0, Waitlist
- Where
- 2 sites in Canada, Finland
- Volunteers
- 300 people
- Sponsor
- The Royal Ottawa Mental Health Centre
Posttraumatic Stress Disorder
Optimizing Posttraumatic Stress Disorder Treatment: Prolonged Exposure (PE) Versus PE Plus Sertraline
The specific aims of this study are: 1. To compare the effectiveness of a cognitive behavioral therapy (prolonged exposure, PE) to that of PE and medication (sertraline). 2.
- Trial name
- OPT (NCT01600456)
- Testing
- Prolonged exposure (PE), PE plus Sertraline
- Where
- 2 sites in United States
- Volunteers
- 150 people
- Sponsor
- Case Western Reserve University
Postnatal Depression
Behavioural Interventions for Postnatal Depression: a RCT Study
Randomized-controlled trial on the effectiveness of managing postnatal depression mothers at primary care clinics using Cognitive-behavioural therapy treatment by nurses as adjunct to management by Medical Officer as compared to…
- Trial name
- NCT03196726
- Testing
- Brief Cognitive Behavioral Therapy, standard management based on Clinical Practice Guideline
- Where
- 6 sites in Malaysia
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Ministry of Health, Malaysia