Clinical trials: Cognitive Changes
Cognitive Change
Assessing the Effects of the Muse Meditation System on Cognition and Well-being
Interaxon markets a head-worn EEG biofeedback device ('Muse') to encourage and aid effective meditation and sleep. This device has been previously shown to improve workplace wellness, fatigue and quality of life, and performance…
- Trial name
- MuseCog (NCT04790929)
- Testing
- Muse, Meditation Coaching
- Where
- Canada
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Western University, Canada
Social Isolation, Mental Status Change
Effects of Arts Engagement on Physical Performance, Cognition, Social Isolation, and Self-Perception in Older Adults
The purpose of this community-engaged project is to examine how taking part in different arts (dance \& music), compared to control (no arts) affects older adults' Health-Related Quality of Life (HRQoL using the Short Form-20(SF)…
- Conditions
- Social Isolation, Mental Status Change, Cognitive Impairment, Physical Activity
- Trial name
- SHARe (NCT04281654)
- Testing
- Active Social Conversation
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- George Mason University
Physiological Stress, Cognitive Change
Effects of Prebiotics on Cognition and Health
This research intervention aims to examine the effects of prebiotic consumption on changes in behavioral and biological measures of cognition and stress among adults.
- Conditions
- Physiological Stress, Cognitive Change, Gastrointestinal Health
- Trial name
- EPOCH-2 (NCT04551937)
- Testing
- Lactose Free 1% Milk, Lactose Free 1% Milk + 10 g prebiotic
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Presymptomatic Disease, Mild Cognitive Impairment
Digitally-enhanced, Decentralized, Multi-omics Observational Cohort
The study is carried out as part of the GR2021 Priority project "Healthy Brains for life (Age 20-99): Digitally-enhanced personalized medicine study ANANEOS" and code numbered GR-00546 and it will look at the decentralized and…
- Conditions
- Presymptomatic Disease, Mild Cognitive Impairment, Memory Loss (Excluding Dementia), Cognitive Change
- Trial name
- ANANEOS (NCT04701177)
- Testing
- Teleph0s digital phenotyping platform
- Where
- 4 sites in Greece, Spain
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- Greece 2021 Committee
Alzheimer, Cognitive Unimpaired
Brain Heath Service for Prevention of AD
The aim of the program to serve as a prototype for future preventive program for AD in the region. The program will recruit elderly participants.
- Conditions
- Alzheimer, Cognitive Unimpaired, Mild Cognitive Impairment
- Trial name
- BEAT AD (NCT07834528)
- Testing
- medical referral and/or educational programs
- Where
- China
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Psychological Distress, Quality of Life
The Effectiveness of Culturally Adapted Cognitive Behavioral Intervention Among COVID-19 Survivors
The effectiveness study for Culturally-Adapted Cognitive Behavioral Intervention (CA-CBI) will be conducted with individuals infected with and recovered from Coronavirus disease (COVID-19) to measure if this intervention is…
- Conditions
- Psychological Distress, Quality of Life, Depressive Symptoms, Anxiety
- Trial name
- NCT04949061
- Testing
- Culturally Adapted Cognitive Behavioral Intervention (CA-CBI), Enhanced Treatment as Usual (ETA-U)
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Koç University
Overweight and Obesity, Cognitive Change
The Effect of Ketone Ester Supplementation and Ketogenic Diet on Brain Plasticity in Overweight/Obese Adults
This project comprises an initial crossover placebo-controlled neurophysiological study to ascertain the effect of acute ketone ester ingestion on motor cortex plasticity, followed by a second 2-week intervention study aimed to…
- Conditions
- Overweight and Obesity, Cognitive Change, Psychophysiologic Reaction
- Trial name
- NCT06368297
- Testing
- Ketone Monoester Supplementation, Ketogenic diet
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Macau
Sleep Deprivation, Burnout, Professional
Cognitive Performance After a Night Shift in Internal Medicine Residents
A quasi-experimental design where internal medicine residents in a high complexity hospital were assessed after a 24-hour shift for cognitive impairment by a trained neurologist.
- Conditions
- Sleep Deprivation, Burnout, Professional, Cognition Disorders
- Trial name
- NCT04053556
- Where
- Argentina
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hospital Italiano de Buenos Aires
Mental Processes, Cognitive Change
The Effects of Mirtoselect®, Virtiva®, and Enovita® on Cognitive Performance and Mood States
This is a randomized, double-blind, placebo-controlled, 4-week intervention clinical study assessing the efficacy of Mirtoselect®, Virtiva® Plus, and Enovita® on cognitive performance and mood states, and the occurrence of…
- Conditions
- Mental Processes, Cognitive Change, Mood Change
- Trial name
- NCT06309914
- Testing
- Enovita Grape Seed Extract, Mirtoselect Bilberry Extract, Virtiva Plus Ginko Biloba Extract
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Applied Science & Performance Institute
Subjective Cognitive Decline
Effects of Online Training Aimed at Increasing Participation in Everyday Life During a Pandemic (SCD Online).
This study evaluates the efficacy of Real-World Strategy Training (RWST) compared to a psycho-education workshop for improving everyday life performance in older adults with subjective cognitive decline (SCD).
- Trial name
- NCT04439500
- Testing
- Real World Strategy Training, Brain Education
- Where
- Canada
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Baycrest
Occupational Health, Sleep
Using Cognitive-Behavioral Change and Mobile Technology to Improve RN Sleep and Fatigue
The U.S. registered nurse (RN) workforce is the largest in the Healthcare and Social Assistance Sector and is at high risk for injuries and errors due to poor sleep and fatigue.
- Conditions
- Occupational Health, Sleep, Fatigue, Nurse
- Trial name
- RN-SLEEP (NCT06105307)
- Testing
- RN-SLEEP, Healthy Habit - Educational Control
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
Cognitive Change, Beta-Thalassemia
Assessment of Cognitive Function, Fatigue and Health Related Quality of Life in Children With Beta Thalassemia
This study aims to: Assess the cognitive function in children with beta thalassemia Evaluate the fatigue in beta thalassemic children Assess the health related quality of life measures in children with beta thalassemia.
- Conditions
- Cognitive Change, Beta-Thalassemia, Fatigue, Quality of Life
- Trial name
- NCT05469230
- Where
- Egypt
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Cairo University
Depressive Symptoms
Thrive, a Computerized Cognitive Behavior Therapy Program to Treat Depression
This study evaluates a culturally-modified version of Thrive, a computerized Cognitive Behavior Therapy program to treat depressive symptoms, syndromes, and disorders among rural Montanans.
- Trial name
- NCT03244878
- Testing
- Thrive
- Where
- United States
- Volunteers
- 464 people, healthy volunteers welcome
- Sponsor
- Montana State University
Tetraplegia, Hypothermia
Thermoregulation and Cognition During Cool Ambient Exposure in Tetraplegia
The ability to maintain normal core body temperature (Tcore = 98.6°F) is impaired in persons with a cervical spinal cord injury (tetraplegia).
- Conditions
- Tetraplegia, Hypothermia, Mild Cognitive Impairment
- Trial name
- NCT02379156
- Testing
- Midodrine Hydrochloride, Cool Temperature
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- James J. Peters Veterans Affairs Medical Center
Depression
iCBT and ABM for Reducing Depressive Symptoms in Firefighters
The study aimed to examine the impact of a combined internet-delivered Cognitive Behavioral Therapy (iCBT) and Attention Bias Modification (ABM) intervention to reduce depressive symptoms in firefighters.
- Trial name
- NCT05741684
- Testing
- Internet-delivered Cognitive Behavioral Therapy, Attention Bias Modification
- Where
- China
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Adai Technology (Beijing) Co., Ltd.
Cognitive Change, Child Development
Conectar Jugando: Board Games in Elementary Classrooms (6-12 Years Old) to Improve Executive Functions
Executive functions are cognitive processes that have been frequently related to adequate academic performance in the scientific literature.
- Trial name
- CJ-Aula (NCT05143294)
- Testing
- Conectar Jugando Classroom Program
- Where
- Spain
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Brain In Game scientific-technical service
Healthy
Posturing Effects on Perception of Time and Perceptions of the Provider-Patient Interaction in the Emergency Department
Study Objective: To examine the perceptions of time spent at the bedside; perceptions of bedside manner; and patient perceptions of the provider-patient interaction offered by emergency providers when they sit versus when they…
- Trial name
- NCT00170105
- Where
- United States
- Volunteers
- 244 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Change in Cognitive Function and Fatigue During Extended Performance of the Cognitive Demand Battery (CDB) at 1, 3 and 6 Hours Post Consumption, Change in Long Term Declarative Memory at 1, 3 and 6 Hours Post-intervention.
Plant Based Extracts and Cognition
Acute, randomized, placebo controlled, double blind, 4 arm crossover study to determine the effect of different combinations of plant based extracts on cognitive function and cerebral blood flow.
- Trial name
- CEOPTB (NCT02202629)
- Testing
- Beverage containing plant based extracts
- Where
- United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Cognitive Change
Effectiveness of a 12 Week Theory Driven Intervention Promoting Adherence to the MIND Diet
This study aims to test the feasibility and acceptability of a 12 week online dietary promoting MIND diet behaviour. This study also tests the effectiveness of the MIND diet on cognitive function, mood, quality of life and…
- Trial name
- NCT04654936
- Testing
- MIND diet, MIND diet with no support
- Where
- United Kingdom
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- University of Ulster
Cognitive Change
Examining the Effectiveness of Cognitive Training
The present study addresses whether placebo effects can possibly account for previous findings in the field, as well as ascertains whether placebo-based mechanisms can be deliberately harnessed for impact.
- Trial name
- NCT04344028
- Testing
- True Cognitive Training Program, Control Cognitive Training Program, Positive Expectation Induction
- Where
- 3 sites in United States
- Volunteers
- 287 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison