Clinical trials: Cognitive Changes
Insulin Resistance, Cognitive Impairment
Effect of Aging on Bariatric Surgery-induced Changes in Metabolism and Cognition
The investigators hypothesize that the improvements in insulin sensitivity, beta (β)-cell function, and inflammation will be greater, and the improvement in sarcopenic obesity will be less, in younger versus older individuals…
- Trial name
- NCT02088190
- Testing
- Sleeve gastrectomy
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Healthy Lifestyle, Home Environment Related Disease
HomeStyles-2: Shaping HOME Environments and LifeSTYLES to Prevent Childhood Obesity
Parents are children's primary role models, are food and physical activity gatekeepers, and create the structure/lifestyle environment within the home.
- Conditions
- Healthy Lifestyle, Home Environment Related Disease, Cognitive Change, Child Behavior
- Trial name
- HomeStyles-2 (NCT04802291)
- Testing
- HomeStyles-2: Obesity Prevention Program for Families with Children in Middle Childhood
- Where
- United States
- Volunteers
- 459 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Cognitive Change
Patient Centered-Rehabilitation ver111090.1
As we age, a number of factors can reduce our cognitive (or thinking) abilities. This study will evaluate whether transcranial electrical stimulation (TES), which uses small amounts of electricity to modulate brain functioning…
- Trial name
- PCN1 (NCT03034954)
- Testing
- Active HD-tDCS
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Cognitive Change, Well-Being, Psychological
Impact of GPT Use on Essay Writing Performance and Cognitive Abilities
The goal of this randomized controlled lab experiment is to examine if using generated artificial intelligence (AI) technology will affect people's academic performance and cognitive abilities in the context of analytical writing…
- Trial name
- NCT06511102
- Testing
- GPT Support
- Where
- Germany
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University Hospital Heidelberg
Heart Failure (HF)
A Study on the Correlation Between Cardiac-Cerebral Oxygenation Reserve and Cognitive Function Changes in Heart Failure Patients
At different stages of heart failure (HF), the cardiac and cerebral oxygen reserve exhibits varying degrees of decline due to chronic hypoxia and microvascular dysfunction caused by reduced cardiac output, leading to cognitive…
- Trial name
- NCT07485816
- Testing
- breathing training
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Yan'an Affiliated Hospital of Kunming Medical University
Healthy Volunteers, General Anaesthesia
Neuroplasticity Induced by General Anaesthesia
The aim of this study is to use magnetic resonance imaging to explore and compare possible de novo neuroplastic changes induced by the isolated effects of the hypnotic agents sevoflurane and propofol, respectively.
- Conditions
- Healthy Volunteers, General Anaesthesia, Neuroplasticity
- Trial name
- DANA1 (NCT04125121)
- Testing
- Sevoflurane-propofol
- Where
- 2 sites in Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Signe Sloth Madsen
Cerebral Hemodynamics, Cognitive Change
Effects of Pulsed Electromagnetic Fields (PEMFS) On Cerebral Haemodynamics
The investigators are looking to determine the effects of PEMFs device on cerebral blood flow and cognition in healthy volunteers.
- Trial name
- EPOCH (NCT03944993)
- Testing
- Pulsed Electromagnetic Fields Therapy (Dominant leg), Pulsed Electromagnetic Fields Therapy (Non-dominant leg)
- Where
- Singapore
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Cognitively Normal, Mild Cognitive Impairment
Longitudinal Changes of [18F]PI-2620 Positron Emission Tomography in Subjects With Cognitively Normal, Mild Cognitive Impairment and Alzheimer's Disease
The overall goal of this imaging trial is to evaluate crosssectional difference and longitudinal changes of [18F]PI-2620, a tau targeted positron emission computed tomography radioligand, in cognitively normal individuals, and…
- Conditions
- Cognitively Normal, Mild Cognitive Impairment, Alzheimer Disease
- Trial name
- NCT03903211
- Testing
- [18F]PI-2620
- Where
- South Korea
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Jae Seung Kim
Diet Modification
Cannabinoid Supplementation on Vascular and Cognitive Function
Cannabidiol (CBD) is a bioactive cannabinoid compound in marijuana (cannabis sativa), but unlike Δ9 tetrahydrocannabinol (THC), lacks the psychoactivity effect of THC.
- Trial name
- NCT03295903
- Testing
- Cannabidiol supplement
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Change in Cognitive Function and Fatigue During Extended Performance of the Cognitive Demand Battery (CDB) at 1, 3 and 6 Hours Post Consumption, Change in Long Term Declarative Memory at 1, 3 and 6 Hours Post-intervention.
Plant Based Extracts and Cognition
Acute, randomized, placebo controlled, double blind, 4 arm crossover study to determine the effect of different combinations of plant based extracts on cognitive function and cerebral blood flow.
- Trial name
- CEOPTB (NCT02202629)
- Testing
- Beverage containing plant based extracts
- Where
- United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Memory Encoding, Memory
Unconscious Mind Training
H22 - Unconscious Mind Training and Memory Encoding Phase 2.1 in progress. The core problem this clinical trial, H22, seeks to address is the pervasive challenge of modifying deeply ingrained, often unconscious, unwanted…
- Conditions
- Memory Encoding, Memory, Behavior Change Interventions, Habits
- Trial name
- NCT07597603
- Testing
- Intervention H22
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Dream Video LLC
Healthy Lifestyle, Home Environment Related Disease
HomeStyles-2: Shaping HOME Environments and LifeSTYLES to Prevent Childhood Obesity in SNAP-Education
Childhood obesity prevention efforts are needed in the United States, especially for families with low income. Educating parents and caregivers on simple lifestyle and affordable home environment changes is an effective strategy…
- Conditions
- Healthy Lifestyle, Home Environment Related Disease, Child Behavior, Cognitive Change
- Trial name
- NCT05019339
- Testing
- Healthy HomeStyles, Eat Healthy Be Active
- Where
- United States
- Volunteers
- 247 people, healthy volunteers welcome
- Sponsor
- University of Florida
Healthy
A Study Investigating the Effectiveness of a LifeSeasons NeuroQ Supplement With Lifestyle Changes to Improve Cognitive Function in Healthy Adults Who Have One or More Risk Factors for Cognitive Decline
The objective of this study is to evaluate the efficacy of a NeuroQ supplement designed by Dr. Bredesen to complement his Lifestyle modification protocol.
- Trial name
- NCT04149639
- Testing
- NeuroQ
- Where
- 2 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- LifeSeasons Inc.
Aging, Aging Problems
Brain Health Virtual Reality Study
The Interventions for Brain Health Virtual Reality Study is a NIH-funded clinical research trial at the University of California San Diego (UCSD) Health under the supervision of the study principal investigator Dr. Judy Pa.
- Conditions
- Aging, Aging Problems, Memory Loss, Memory Impairment
- Trial name
- NCT06124339
- Testing
- Physical Activity, Cognitive Activity (VR), Physical and Cognitive Activity
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Complex Regional Pain Syndromes
Physical and Psychological Changes in CRPS Patients Undergoing Multimodal Rehabilitation
The goal of this clinical trial is to learn about cognitive changes during rehabilitation in CRPS patients. The main questions it aims to answer are: What are the cognitive changes in CRPS? Do cognitive functions change during…
- Trial name
- NCT05696587
- Testing
- Multimodal rehabilitation
- Where
- Poland
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- National Institute of Geriatrics, Rheumatology and Rehabilitation, Poland
Fetal Growth Abnormalities, Fetal Weight
Impact of AI Feedback on Ultrasound Biometry Accuracy Across the Expertise Levels
Objective: To evaluate the impact of real-time AI feedback on fetal biometry accuracy and investigate the Expertise Reversal Effect-whether AI benefits diminish as user experience increases.
- Trial name
- NCT07476638
- Testing
- AI interventional group
- Where
- 3 sites in Denmark
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Copenhagen Academy for Medical Education and Simulation
Sleep Disruption, Sleep Hygiene
Sleep Hygiene During Ramadan
Ramadan fasting often disrupts sleep patterns, which can affect alertness and physical performance in student-athletes. This study tested whether a brief sleep education program designed for Ramadan could help improve sleep…
- Conditions
- Sleep Disruption, Sleep Hygiene, Ramadan Fasting
- Trial name
- SHIR (NCT07639229)
- Testing
- Culturally Adapted Sleep Hygiene Education Program
- Where
- Tunisia
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- The Higher Institute of Sport and Physical Education of Sfax
Obesity, Overweight
Changing Eating Behavior Using Cognitive Training
Obesity is a global health problem. New and more efficient interventions are needed to overcome this disease. This randomized clinical trial aims to evaluate the effectiveness of changing eating behavior using cognitive training.
- Conditions
- Obesity, Overweight, Weight Loss
- Trial name
- NCT04450524
- Testing
- Hypnosis, Food inhibition training, Control
- Where
- 2 sites in Romania
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Babes-Bolyai University
Mild Cognitive Impairment, Caregiver Burnout
Improving Physical Activity With Cognitive Impairment
Individuals with mild cognitive impairment are often physically inactive and at risk for progressing to dementia. Physical inactivity is considered a modifiable risk factor for dementia.
- Trial name
- NCT05370118
- Testing
- Telerehabilitation physical activity behavioral (TPAB) intervention
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Creighton University
Alteration of Cognitive Function
The Effect of Breakfast Size Prior to Morning Exercise on Cognition, Mood and Appetite in Habitually Active Women
Both regular exercise and breakfast consumption have well known health benefits. Consuming breakfast prior to morning exercise may influence appetite, mood and cognitive function later in the day.
- Trial name
- NCT01711008
- Testing
- Cereal, No breakfast
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Northumbria University