Clinical trials: Cognitive Changes
Obesity
Enhanced Internet Behavior Therapy for Treating Obesity
The purpose of this study is to compare two Internet-based behavioral weight loss programs.
- Trial name
- NCT00212238
- Testing
- internet behavioral weight loss program
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Cognitive Change, Reaction Time
Effects of A-GPC on Reaction Time and Cognitive Function
This is a randomized, double blind, crossover design study which measures the effect of alpha-glycerylphosphorylcholine (A-GPC) on reaction time and cognitive function in non-resistance trained males and females.
- Trial name
- NCT03903250
- Testing
- A-GPC, Sugar
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Mary Hardin-Baylor
Dementia Prevention, Subjective Cognitive Impairment
The Brain Health PRO Online Risk Factor Reduction Study to Prevent Dementia
This study will recruit participants at risk for dementia to participate in an online educational program called Brain Health PRO (BHPro).
- Conditions
- Dementia Prevention, Subjective Cognitive Impairment, Mild Cognitive Impairment, Cognitive Change
- Trial name
- BHPROOF (NCT07364019)
- Testing
- Brain Health PRO
- Where
- Canada
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Cognitive Change, Motor Activity
Group Music Practice Enhances Development
This randomized controlled trial shows for the first time that focused musical instrumental practice as compared to traditional sensitization to music provokes multiple transfer effects in the cognitive and sensorimotor domain.
- Trial name
- OC (NCT04200794)
- Testing
- musical instrumental training, sensitization to music
- Where
- Switzerland
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- School of Health Sciences Geneva
Cognitive Change, Mood
The Effects of Resveratrol Supplementation on Inflammation and Cognitive Performance in Healthy Adults
Previous research has suggested that high levels of systemic inflammation can contribute to cognitive deficits and additional health problems; consumption of polyphenols have been shown to have an anti-inflammatory effect.
- Conditions
- Cognitive Change, Mood, Systemic Inflammation
- Trial name
- NCT04314739
- Testing
- Resveratrol
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Cognitive Change
Immediate and Residual Effects of Functional Chewing Gum on Concentration
Previous research suggests that chewing gum may influence several functions including attention and alertness. Gum can also be used as a vehicle for delivering ingredients that have the ability to modulate attention and mood.
- Trial name
- NCT05544500
- Testing
- Functional Gum, Basic Chewing Gum
- Where
- United Kingdom
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Vascular Stiffness, Cognitive Change
Blueberry Study Aimed at Improving Cognition and Peripheral Blood Flow
Blueberries are rich in the content of a variety of biologically active chemicals that contribute to their health properties. The consumption of blueberries has beneficial effects on vascular function and brain health and…
- Conditions
- Vascular Stiffness, Cognitive Change, Blood Pressure
- Trial name
- NCT04015258
- Testing
- Blueberries, Blueberry powder, Blueberry components capsules
- Where
- United Kingdom
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Alzheimer's Disease
Dose Response Study of Aerobic Exercise in Older Adults
This is a randomized, 26-week study of supervised exercise assessing three doses of exercise in sedentary individuals 65 years of age and over with age-related cognitive changes.
- Trial name
- NCT01129115
- Testing
- Nonexercise control group, Aerobic Exercise Group 1, Aerobic Exercise Group 2
- Where
- United States
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Jeff Burns, MD
Cognitive Change
Yoga Training and Retinal Vasculature
This study will compare the impact of a novel high-speed, cued yoga program to a standard yoga program on retinal microvasculature, cognition and neuromuscular function.
- Trial name
- NCT06099405
- Testing
- High-speed, Cognitive Challenge Yoga, Traditional yoga
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Miami
BDNF, Cognitive Performance
Acute Neurochemical and Cognitive Changes After HIIT vs MICT/LICT
This study examines whether the intensity of a single running session changes a blood marker related to brain health (brain-derived neurotrophic factor, BDNF), blood lactate, and performance on a short thinking task that measures…
- Conditions
- BDNF, Cognitive Performance, Lactate, Exercise Intensity
- Trial name
- ANCCR (NCT07379879)
- Testing
- Low Intensity Exercise, Moderate-Intensity Continuous Exercise, High-Intensity Interval Training
- Where
- Turkey (Türkiye)
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Aksaray University Training and Research Hospital
Heat Stress, Physiological Stress
Impact of Indoor Overheating on Physiological Strain in Children
Communities worldwide are experiencing increasing heat extremes that challenge the limits of human thermoregulation, particularly among vulnerable populations such as children.
- Conditions
- Heat Stress, Physiological Stress, Cognitive Change
- Trial name
- NCT07261202
- Testing
- Simulated exposure to indoor overheating
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Cognitive Change
Cognitive Testing in Diverse Populations to Further the Objective and Clinical Understanding of Cognivue Study
An open-label, multi-site, validity and reliability study to obtain data on the Cognivue 5-Minute Screening and Cognivue 10-Minute Assessment tests to assess scoring and normative ranges and compare against other cognitive tests…
- Trial name
- FOCUS (NCT05712005)
- Where
- United States
- Volunteers
- 1,437 people, healthy volunteers welcome
- Sponsor
- Cognivue, Inc.
Low Back Pain
Evaluating the Impact of a Champion on Implementation of the Back Skills Training (BeST) Program in Canada
There is global recognition in clinical guidelines and governing bodies that low back pain (LBP) should be managed with a biopsychosocial approach.
- Trial name
- NCT04377529
- Testing
- Local Champion
- Where
- Canada
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Memorial University of Newfoundland
Cognitive Change, Stress, Psychological
Acute and Chronic Effects of Avena Sativa on Cognition and Stress
The flavanoid and terpene phytochemicals present in wild green oat interact with multiple mechanisms relevant to brain function; including those which would modulate cognition and stress.
- Conditions
- Cognitive Change, Stress, Psychological, Mood
- Trial name
- NCT03689348
- Testing
- Avena sativa
- Where
- United Kingdom
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Cognitive Change
Transcranial Near-Infrared Light in Healthy Subjects: a Cerebral Blood Flow Study With Diffuse Correlation Spectroscopy
Transcranial Light Therapy involves non-invasive and invisible beams of light that increase energy metabolism in the brain. Transcranial light therapy has been found to promote brain metabolism.
- Trial name
- NIR-Flow (NCT03740152)
- Testing
- Transcranial Light Therapy
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Substance Use Disorders
Effectiveness of a Brief Cognitive and Behavioral Skills Program on Stage Transitions for Chronic Ketamine Abusers
In recent years ketamine abuse becomes prevalent in youth in some Asian countries. Chronic ketamine abuse may lead to uropathology and cognitive impairments.
- Trial name
- NCT03644719
- Testing
- Cognitive behavioral skills training
- Volunteers
- 409 people, healthy volunteers welcome
- Sponsor
- National Taiwan University
Cognitive Change
Validating the Digital Virginia Tech Carilion Cognitive Examination
Currently, cognitive screening is performed in-person after the individual expresses symptoms or it is noticed by someone close to them and are largely done in clinical settings.
- Trial name
- VTC-Cog (NCT04265898)
- Testing
- The Digital Virginia Tech Carilion Cognitive Examination
- Volunteers
- healthy volunteers welcome
- Sponsor
- Carilion Clinic
Memory Deficits, Aging
The Effect of Tai Chi and Therapy by Dance and Movement on Blood Irisin Levels in Older Adults Over 65 Years of Age.
The aim of this project is to estimate the effects of therapy with dance and movement and Tai Chi on irisin plasma levels, a myokine with proven neuroprotective effects, in the context of baseline levels of cognitive function and…
- Conditions
- Memory Deficits, Aging, Cognitive Impairment, Physical Activity
- Trial name
- NCT05363228
- Testing
- Therapy by Dance and Movement, Tai Chi
- Where
- 2 sites in Czechia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Charles University, Czech Republic
Cognitive Performance, Inflammation
Peanut Consumption on Cognitive, Weight, and Inflammation
A multi-school, two-arm parallel cluster-randomized controlled trial will be conducted in 200 healthy young adolescents from Barcelona (Spain) to evaluate the effect of peanut consumption on cognitive performance, weight…
- Conditions
- Cognitive Performance, Inflammation, Weight Change, Body, Adolescents
- Trial name
- PEANUTY (NCT06127511)
- Testing
- Food (peanut)
- Where
- Spain
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- University of Barcelona
Learning Disorders, Learning Disabilities
Efficacy of the MovinCog Intervention in Children
This study aims to test the efficacy of the MovinCog Intervention to enhance cognitive abilities in children 7-15 yrs. The intervention consists of two parts: a physical exercise regimen, based on high-intensity training, and a…
- Conditions
- Learning Disorders, Learning Disabilities, Cognitive Change
- Trial name
- NCT03255499
- Testing
- Exercise, Cognitive, Active control
- Where
- New Zealand
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of Auckland, New Zealand