Clinical trials: Cognitive Communication Disorder
Stroke, Caregiver Burden
Instant Message-delivered Early Psychological Intervention in Stroke Family Caregivers
Psychological distress including depression and anxiety is a major component of caregiver stress, and its negative impact on caregivers' health and well-being has been established in the literature.
- Conditions
- Stroke, Caregiver Burden, Mobile Phone Use
- Trial name
- EPI (NCT05907005)
- Testing
- iCBT-based EMI
- Where
- 5 sites in Hong Kong
- Volunteers
- 152 people
- Sponsor
- The University of Hong Kong
Dyslexia, Developmental
Poly-unsaturated Fatty Acids and Developmental Dyslexia
Poly-unsaturated fatty acids (PUFAs) represent a component of lipids that covers a relevant role in human diet and biological functions such as provision of energy, functionality of cell membranes and tissue metabolism.
- Trial name
- NCT04287530
- Testing
- Poly-unsaturated fatty acids supplementation, Neuropsychological intervention
- Where
- 2 sites in Italy
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Autistic Disorder, Autism Spectrum Disorder
SQUED™ Series 28.1 Home-use and Treatment of Autowave Reverberator of Autism
Locomotor, transport and information functions in human body systems are carried out by active media in autowave regimes! Any living organism is a (micro-macro-mega) hierarchy of autowave subsystems-an ensemble of loosely coupled…
- Conditions
- Autistic Disorder, Autism Spectrum Disorder, Child Development Disorders, Pervasive, Neurodevelopmental Disorders
- Trial name
- SQUED™ (NCT03222375)
- Testing
- SQUED™ series 28.1 home-use
- Where
- 2 sites in United States, Ukraine
- Volunteers
- 80 people
- Sponsor
- American Federation of Medical Synergetics
Mild Cognitive Impairment
Keeping on Course: A Communication-Focused Psychoeducational Program
The goal of Keeping on Course is to develop and test a psychoeducation program to provide dyads facing mild cognitive impairment (MCI) with communication skills and strategies that will establish or restore a sense of agency as…
- Trial name
- NCT05423912
- Testing
- Keeping on Course Program
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Emory University
Deafness, Speech Intelligibility
Evaluating Short-term Effects of Computerized Brain Fitness Exercises in Adult Cochlear Implant and/or Hearing Aid Users
In this study we are testing computer-based brain fitness exercises. The games are designed to improve people's cognitive abilities brain functions, like memory, concentration, and ability to do two things at once.
- Trial name
- NCT01732887
- Testing
- Cognitive fitness training
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- Aaron Newman
Alzheimer Disease, Alzheimer's Disease (Incl Subtypes)
Amyloid Prediction in Early Stage Alzheimer's Disease Through Speech Phenotyping - PAST Extension
The primary objective of the study is to evaluate whether a set of algorithms analysing acoustic and linguistic patterns of speech can detect amyloid-specific cognitive impairment in early stage Alzheimer's disease, based on…
- Conditions
- Alzheimer Disease, Alzheimer's Disease (Incl Subtypes), Preclinical Alzheimer's Disease, Prodromal Alzheimer's Disease
- Trial name
- PAST-US (NCT04937959)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Novoic Limited
Alzheimer's Disease, Mild Cognitive Impairment
Performance of AclarusDx™, a Blood-Based Transcriptomic Test for AD, in US Patients Newly Referred to a Memory Center
The purpose of this study is to assess the performance of AclarusDx™, an investigational blood test detecting gene expression information, and intended to help physicians in making an Alzheimer's Disease diagnosis in patients…
- Conditions
- Alzheimer's Disease, Mild Cognitive Impairment, Vascular Dementia, Fronto-temporal Dementia
- Trial name
- NCT01465360
- Where
- 3 sites in United States
- Volunteers
- 160 people
- Sponsor
- Exonhit
Attention Deficit Hyperactivity Disorders, Developmental Delays
Cognitive Training for Attention Deficit Hyperactivity Disorder and Developmental Delays
To explore whether children with Attention Deficit Hyperactivity Disorder and developmental delays who receive cognitive training and conventional rehabilitation can improve executive function more than traditional rehabilitation…
- Trial name
- NCT06277440
- Testing
- cognitive training, active control
- Where
- Taiwan
- Volunteers
- 20 people
- Sponsor
- Taipei Medical University
Alzheimer's Disease, MCI Due to AD
Language, Speech and Motor Function in MCI Due to AD and Alzheimer's Disease
The goal of this observational cross-sectional study is to explore the characteristics of language, speech, and motor function in persons with Mild Cognitive Impairment due to Alzheimer's disease ("MCI due to AD") and persons…
- Conditions
- Alzheimer's Disease, MCI Due to AD, Dementia Alzheimers
- Trial name
- NCT06508268
- Testing
- GAITRite walkway system OR 4-meter walking speed test, Jamar hand dynamometer, Picture description task
- Where
- Netherlands
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- Hanze University of Applied Sciences Groningen
Aphasia, Stroke
Brain Correlates of Multimodal Rehabilitation in Chronic Post-stroke Aphasia
Post-stroke aphasia (PSA), the partial or total loss of the ability to produce and/or understand language associated with stroke, is a highly prevalent and disabling disorder that negatively impacts the personal, social and…
- Trial name
- NCT04134416
- Testing
- Donepezil, Intensive-Language Action Therapy, Transcranial direct current stimulation
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- University of Malaga
Schizophrenia, Psychosis
Multi-site Communication Deficits in Schizophrenia
Multi-site Communication Deficits Underlying Cognitive Dysfunction in the Prodromal Phase and First Episode of Schizophrenia
- Trial name
- NCT01317121
- Where
- Germany
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Autism Spectrum Disorder, Social Communication Disorder
To Evaluate the Efficacy and Safety of 'NDTx-01' in Patients With ASD or SCD
The purpose of this study is to demonstrate the superiority of the treatment of cognitive therapy software 'NDTx-01' compared to TAU (Treatment-As-Usual).
- Trial name
- NCT06446193
- Testing
- NDTx-01, TAU
- Where
- 5 sites in South Korea
- Volunteers
- 86 people
- Sponsor
- Neudive Inc.
Alzheimer Disease, Preclinical Alzheimer's Disease
Amyloid Prediction in Early Stage Alzheimer's Disease From Acoustic and Linguistic Patterns of Speech
The primary objective of the study is to evaluate whether a set of algorithms analysing acoustic and linguistic patterns of speech can detect amyloid-specific cognitive impairment in early stage Alzheimer's disease, as measured…
- Conditions
- Alzheimer Disease, Preclinical Alzheimer's Disease, Prodromal Alzheimer's Disease, Alzheimer's Disease (Incl Subtypes)
- Trial name
- AMYPRED (NCT04828122)
- Where
- 4 sites in United Kingdom
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- Novoic Limited
Cognitive Impairment, Mild, Dementia, Mild
Identify the Benefits CAREGIVERSPRO-MMD Platform Use Based on the Information and Communications Technology, Dedicated to the Support and Assistance of Dyads Living With Neurocognitive Diseases and Their Primary Caregivers
Our main goal is to test a web platform accessible by computers, smartphones and tablets, addressed specifically to caregivers and people with mild cognitive deterioration or mild to moderate dementia providing added value…
- Trial name
- CAREGIVERSPRO (NCT03536975)
- Testing
- Platform
- Where
- 2 sites in France
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University Hospital, Rouen
Aphasia, Stroke
Brain-based Understanding of Individual Language Differences After Stroke
Strokes often cause a loss of communication ability, referred to as aphasia, as well as cognitive difficulties. Each stroke survivor has a unique pattern of strengths and weaknesses in communication and cognition, and a unique…
- Conditions
- Aphasia, Stroke, Alexia
- Trial name
- BUILD (NCT04991519)
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Schizophrenia
Effects of Brain Stimulation on Higher-Order Cognition
The purpose of this study is to better understand the neural correlates of higher-order cognition, both in the healthy brain and in schizophrenia, and to determine how these mechanisms are modulated by transcranial direct current…
- Trial name
- NCT03814967
- Testing
- Transcranial Direct Current Stimulation
- Where
- United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Post Operative Pain
Parent Nurse Controlled Analgesic in Pediatric Patients With Developmental Delay
The purpose of this study is to compare, the safety, efficacy and level of parent and nurse satisfaction with three methods of opioid administration post-operatively in children (4-18 years of age) with developmental delay.
- Trial name
- PNCA (NCT00743730)
- Testing
- Pain and standard side effect management for PNCA with basal method., Pain and standard side effect management with PNCA without basal, Pain and standard side effect management with IV on an as needed basis method.
- Where
- United States
- Volunteers
- 94 people
- Sponsor
- Medical College of Wisconsin
Speech Intelligibility, Hearing Loss, Sensorineural
The Influence of the Individual Auditory-cognitive Need on the Aided Benefit Using Different Feature Settings
The goal of this clinical trial is to optimize hearing aid benefit based on the individual auditory-cognitive need using different hearing aid features in first-time hearing aid users between 45-80 years old with bilateral Phonak…
- Trial name
- NCT06420037
- Testing
- Hearing aid feature adjustment (frequency compression) of the following hearing aids: Phonak Audéo Paradise/Lumity 70, Hearing aid feature adjustment (noise reduction) of the following hearing aids: Phonak Audéo Paradise/Lumity 70, Cognitive screening and vision screening
- Where
- Belgium
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University Ghent
Breast Cancer, Cognitive Symptoms
Breast Cancer Patients' Cognitive Symptoms After Information About Chemotherapy-Related Cognitive Symptoms
Previous cross-sectional studies have shown that informing cancer patients about potential chemotherapy-related cognitive symptoms may negatively affect perceived cognitive symptoms and verbal memory performance.
- Conditions
- Breast Cancer, Cognitive Symptoms, Cognitive Decline
- Trial name
- CONTEXT (NCT04813965)
- Testing
- Written information about potential chemotherapy-related cognitive symptoms without self-affirmation, Written information about potential chemotherapy-related cognitive symptoms with self-affirmation
- Volunteers
- 148 people
- Sponsor
- Radboud University Medical Center
Right Hemispheric Stroke, Left Hemispheric Stroke
Neural and Cognitive Correlates of Pragmatic Abilities
Pragmatics of language refers to the set of abilities that allow one to use and interpret language according to context and, in general, to communicate effectively.
- Conditions
- Right Hemispheric Stroke, Left Hemispheric Stroke, Traumatic Brain Injury, Right Hemispheric Brain Tumor
- Trial name
- APACS_Neuro (NCT06297044)
- Testing
- Neuropsychological assessment
- Where
- Italy
- Volunteers
- 324 people, healthy volunteers welcome
- Sponsor
- IRCCS San Camillo, Venezia, Italy