Clinical trials: Cognitive Complaint
Subjective Cognitive Decline
Impact of a Cognitive Intervention Enriched With Leisure Activities in Persons With Subjective Cognitive Decline
The team "Cognitive intervention, cognitive reserve and brain plasticity", Team 10, is part of the Canadian Consortium on Neurodegeneration in Aging (CCNA).
- Trial name
- NCT03271190
- Testing
- ENGAGE SPANISH/MUSIC, ENGAGE DISCOVERY
- Where
- 2 sites in Canada
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Centre de Recherche de l'Institut Universitaire de Geriatrie de Montreal
Localized, Operable Non-small Cell Lung Cancer
Cognition and Patients With Lung Cancer
Cognitive complaints in patients treated for cancer can impact their quality of life. Studies show that these cognitive complaints may have multifactorial origins and appear at different stages of the care pathway.
- Trial name
- COGNIPULM (NCT07160751)
- Testing
- Self-questionnaire, Cognitive tests, Assessment of the impact of social vulnerability on patient complaints
- Where
- France
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Healthy Older Adults, Memory Complaints
A Computer-based Memory Strategy Training Program for Older Adults
A computer-based cognitive rehabilitation program based on daily tasks utilising the semantic or perceptual encoding strategies called Enhancing Memory in Daily Life (E-MinD Life) has been developed for Chinese people.
- Conditions
- Healthy Older Adults, Memory Complaints, Mild Cognitive Impairment (MCI)
- Trial name
- NCT07039708
- Testing
- E-MinD Life Semantic, Cognitive stimulation
- Where
- Hong Kong
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Mild Traumatic Brain Injury, Posttraumatic Stress Disorder
Imaging Biomarkers of Mild Traumatic Brain Injury: a Longitudinal Cohort Study
This longitudinal cohort study aims to detect the topographical nature of the white matter microstructure and resting state functional connectivity patterns across the whole brain in the evolution of pathology as a function of…
- Conditions
- Mild Traumatic Brain Injury, Posttraumatic Stress Disorder, Affective and Somatic Complaints, Cognitive Impairments
- Trial name
- NCT02868684
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Sleep
Nutritional Intervention to Improve Sleep Quality and Improve Next-day Mood and Cognitive Benefits
The study aim to test the effect of a meal complement to be taken in combination with an evening meal with a glycemic load of 55, to improve sleep quality.
- Trial name
- NCT05372900
- Testing
- Test Product, Control Product
- Where
- Singapore
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Active Aging Individuals Aged 65 and Over, Aging
Italian Validation of the dNA Scale and Its Correlation With Neurocognitive Variables
The goal of this experimental multicentric intervention study is to validate, in Italian, the dynamic Neurocognitive Adaptation (dNA) Scale, which has already been validated in English, among a healthy elderly population (aged 65…
- Conditions
- Active Aging Individuals Aged 65 and Over, Aging, Mild Cognitive Impairment (MCI), Dementia
- Trial name
- NCT07533084
- Where
- 8 sites in Italy
- Volunteers
- 265 people, healthy volunteers welcome
- Sponsor
- Neuromed IRCCS
Mild Cognitive Impairment
EXCEL: Exercise for Cognition and Everyday Living for Seniors With Memory Complaints
Alzheimer's disease (AD) is a major health issue in Canada; it affects over 8% of the population aged over 65 years. Persons with AD have a reduced quality of life as they become dependent on others for activities of daily living…
- Trial name
- NCT00958867
- Testing
- Exercise program (AT), Exercise training (RT), Exercise training (S & R; control)
- Where
- Canada
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Anxiety
Effect of a Six-week Integrated Attention Training Program on the Cognitive Functions of Older Adults With Co-occurring Anxiety Symptoms and Subjective Cognitive Complaints
The goal of this single-blind randomized control trial is to compare a 6-week Integrated Attention Training Program (IATP) and health education in older people with co-occurrence of anxiety symptoms and subjective cognitive…
- Trial name
- NCT06063265
- Testing
- Integrated Attention Training Program
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hong Kong Baptist University
Subjective Cognitive Complaints
Constructing A Model of Health Promotion and Active Aging for Community-Dwelling Older Adults
Cognitive intervention for people with subjective cognitive complaints can be categorized into cognitive training, cognitive rehabilitation, psychoeducation, lifestyle intervention, etc.
- Trial name
- NCT03612167
- Testing
- cognitive intervention, nutritional group
- Where
- Taiwan
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- National Cheng Kung University
Cognitive Change
An Open-label, Exploratory Study to Investigate the Efficacy of BDNF Essentials® on Cognition
The objective of this open-label, exploratory study is to investigate the efficacy of BDNF Essentials® on cognition in a healthy adult population with self-reported memory complaints.
- Trial name
- NCT04860778
- Testing
- BDNF Essentials
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Researched Nutritionals LLC
Dietary Supplement, Cognition
Nutritional Supplement's Effects on Cognition
This is a prospective, placebo controlled study, examining the effects of dietary supplement's effects on cognition and confirming safety.
- Conditions
- Dietary Supplement, Cognition, Healthy
- Trial name
- NCT05941949
- Testing
- Softgel Cognitive Formulation containing Astaxanthin, Grape Juice Extract and All Natural Vitamin E
- Where
- Australia
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Pharmanex
Aging
Maintaining Independence in Everyday Life Among Seniors With Subjective Cognitive Complaints
The purpose of this study is to determine the effectiveness of cognitive strategies in improving participation in daily activities within older adults who report subjective cognitive decline.
- Trial name
- NCT02655497
- Testing
- Cognitive training, Psychosocial education
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Baycrest
Breast Cancer, Neurocognitive Impairment
Examining a Common Complaint of Women Who Receive Chemotherapy for Breast Cancer- Cognitive Difficulty
This longitudinal project will investigate a common complaint of women who receive chemotherapy for breast cancer- cognitive difficulty.
- Conditions
- Breast Cancer, Neurocognitive Impairment, Quality of Life
- Trial name
- NCT01553097
- Testing
- Neurocognitive impairment observation
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Subjective Cognitive Complaint, Activities Daily Living
Community-based Cohort of Functional Decline in Subjective Cognitive Complaint Elderly
Background With the global population aging and life expectancy increasing, dementia has turned a priority in the health care system.
- Conditions
- Subjective Cognitive Complaint, Activities Daily Living, Dementia, Alzheimer Disease
- Trial name
- NCT04265482
- Where
- Chile
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Geroscience Center for Brain Health and Metabolism (Gero)
Healthy Adults With Subjective Memory Complaints
Effects of HX106 on Improvement in Cognitive-Bio-Markers of Memory Function
The objectives of the current study are to evaluate the efficacy and safety of HX106 in healthy adults with subjective memory complaints for improving cognitive and neurobiolgoical markers of memory.
- Trial name
- NCT01956097
- Testing
- HX106 590mg, HX106 1180mg
- Where
- South Korea
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Ewha Womans University
Cognitive Impairment, RRSO
IMProving Executive Function Study
This is a double-blind, placebo-controlled, crossover study testing whether Vyvanse (lisdexamfetamine; LDX) improves executive functioning (EF) in 100 postmenopausal women who report onset of EF difficulties after oophorectomy.
- Trial name
- IMPRES (NCT03187353)
- Testing
- Lisdexamfetamine
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Neurodegenerative Diseases, Mild Cognitive Impairment
Magnetic Resonance Imaging (MRI) of Brain Iron in Neurodegenerative Disease
Neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease, and multiple sclerosis are recognized as a major health concern at the present time.
- Trial name
- NCT00249080
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- Albany Medical College
Cognitive Ability, General
Body and Brain Exercise for Older Adults With Memory Complaints
The purpose of this study is to investigate whether an exercise class with a cognitive (or brain) training component was more effective than a usual combined aerobic and resistance exercise class for older adults with cognitive…
- Trial name
- NCT02136368
- Testing
- Multi-modal exercise, Mind-Motor Exercise, Balance and range of motion exercises
- Where
- Canada
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Cognitive Symptom, Pre Senile Dementia
Compensatory Training to Support Brain Healthy Lifestyle Changes in Those at Risk for Alzheimer's Disease
The Researchers are trying to better understand if behavioral interventions can help improve memory compensation and engagement in healthy lifestyle behaviors in those with memory concerns but normal mental status exam.
- Conditions
- Cognitive Symptom, Pre Senile Dementia, Alzheimer Disease
- Trial name
- NCT04118985
- Testing
- Cognitive rehabilitation and health behavior change intervention, Self-implementation
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Cognitive Decline
ADL+2.0: Intervention for Prevention of Cognitive Decline in Community-dwelling Older Adults
Singapore's rising dementia incidence with an ageing population presents an urgent need for effective interventions that delay or prevent cognitive decline.
- Trial name
- ADL+ 2 (NCT07141160)
- Testing
- Combined: Mobile app + 6WELLS, Remote mobile based app
- Where
- Singapore
- Volunteers
- 255 people, healthy volunteers welcome
- Sponsor
- Tan Tock Seng Hospital