Clinical trials: Cognitive Control, open to volunteers
Breast Cancer, Cognitive Dysfunction
Remotely Supervised Computerized Cognitive Stimulation to Reduce Post-chemotherapy Cognitive Difficulties in Patients Treated for Localized Breast Cancer
Investigator propose the first French randomized comparative study to assess the efficacy of a remotely supervised online cognitive stimulation program, compared to an unsupervised online cognitive exercise intervention, in…
- Trial name
- COG STIM 2 (NCT06027632)
- Testing
- Cognitive exercises with supervision, Cognitive exercises without supervision
- Where
- 25 sites in France
- Volunteers
- 300 people
- Sponsor
- Centre Francois Baclesse
Psychological Distress, Depression - Major Depressive Disorder
Internet-based Support for Adjustment to Prostate Cancer
The study aims to study the efficacy of internet-based cognitive behavior therapy (ICBT) in reducing subjective distress and comorbid psychiatric symptoms in men diagnosed with prostate cancer.
- Conditions
- Psychological Distress, Depression - Major Depressive Disorder, Insomnia, Anxiety
- Trial name
- ISAC (NCT06766526)
- Testing
- Internet-based cognitive behavioral therapy, Non-directive support
- Where
- Sweden
- Volunteers
- 180 people
- Sponsor
- Linkoeping University
Attention Deficit Hyperactivity Disorder
Development of Virtual Reality-based Interventions to Strengthen Cognitive Skillsets Related to Attention Deficit Hyperactivity Disorder (ADHD): A Pilot Phase I and Randomized Controlled Phase II Trial
Background: Children with attention deficit hyperactivity disorder (ADHD) often have cognitive problems. It may be hard for them to control their behaviors, concentrate for long periods, or make decisions.
- Trial name
- NCT05608434
- Testing
- Non-adaptive Floreo VR control, Floreo Virtual Reality application
- Where
- United States
- Volunteers
- 219 people
- Sponsor
- National Institute of Mental Health (NIMH)
Stroke
Effects of rTMS Combined With Dual-Task Gait Training on Walking and Cognition After Stroke
This randomized, double-blind, placebo-controlled trial will investigate whether repetitive transcranial magnetic stimulation (rTMS) applied to the dorsolateral prefrontal cortex (DLPFC) can enhance the effects of dual-task gait…
- Trial name
- NCT07356687
- Testing
- active rTMS with dual-task training
- Where
- Hong Kong
- Volunteers
- 184 people
- Sponsor
- The Hong Kong Polytechnic University
Older Adults (65 Years and Older), Cognition
Effects of Breathing Exercises on Cognition in Older Adults
The goal of this interventional clinical trial is to investigate the effects of breathing exercises added to balance training on cognitive function in individuals aged 65 years and older.
- Conditions
- Older Adults (65 Years and Older), Cognition, Balance Control in Elderly, Fall Prevention in Healthy Aging
- Trial name
- NCT07505914
- Testing
- Balance Training Program, Inspiratory Muscle Training, Breathing Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Anxiety, Depression
Mental Health INtervention With Digital APPlications (MIND-APP): Evaluating the Effectiveness of the Tankevirus and Grubl Mental Health Apps
The MIND-APP trial is a 3-arm randomized controlled trial (1:1:1 allocation) conducted fully remotely via a bespoke smartphone research platform.
- Trial name
- MIND-APP (NCT07627204)
- Testing
- Tankevirus, Grubl
- Where
- Norway
- Volunteers
- 1,000 people
- Sponsor
- University Hospital, Akershus
Shoulder Dystocia
TelesDystocia: Tele-Support vs. Cognitive Aid in Simulated Shoulder Dystocia
Shoulder dystocia is an unpredictable, time-critical obstetric emergency requiring immediate recognition and rapid execution of established maneuvers.
- Trial name
- TelesDystocia (NCT07772102)
- Testing
- Remote Tele-Support, Cognitive Aid
- Where
- Austria
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Oncology, Cancer-related Cognitive Impairment
Effects of Cognitive Training on Chemotherapy-Induced Cognitive Impairment in Colon Cancer Patients Undergoing Treatment(Chemobrain) in Oncology Patients With Colon Cancer Undergoing Active Treatment
Introduction: With the increasing survival rate in colon cancer, as a result of technological and biomedical advancements, it is essential to thoroughly study the secondary symptoms related to the oncological disease process.
- Conditions
- Oncology, Cancer-related Cognitive Impairment, Cognitive Training, Everyday Cognition
- Trial name
- NCT06710639
- Testing
- Health Education Program, Cognitive Training Program
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Salamanca
Stroke ( 3 Months After Onset), Cognitive Dysfunction ( MMSE < 24 )
The Effects of Virtual Reality-based Training for the Treatment of Neglect Syndrome in Stroke: a Randomized Controlled Trial
This study aims to investigate the effectiveness and underlying recovery mechanisms of a virtual reality-based training program for the treatment of neglect syndrome in stroke patients in the chronic phase (more than three months…
- Conditions
- Stroke ( 3 Months After Onset), Cognitive Dysfunction ( MMSE < 24 ), Unilateral Neglect Syndrome
- Trial name
- NCT07102927
- Testing
- Virtual reality-based training for the treatment of neglect syndrom in stroke, Conventional occupational therapy
- Where
- South Korea
- Volunteers
- 28 people
- Sponsor
- Yonsei University
Antisocial Behavior
Matching Treatments to Cognitive Deficits in Offenders With Substance Use Disorders
The goal of this clinical trial is to investigate the effect of two types of cognitive remediation training on real-world behavioral outcomes including substance use, institutional adjustment, and recidivism following release…
- Trial name
- MCT (NCT06981351)
- Testing
- Attention to Context (ATC) training, Affective Cognitive Control (ACC) training
- Where
- United States
- Volunteers
- 288 people
- Sponsor
- The Mind Research Network
Epilepsy
Methylphenidate for the Treatment of Epilepsy-related Cognitive Deficits
Methylphenidate (MPH) is a stimulant, FDA-approved for the treatment of attention deficit hyperactivity disorder (ADHD). It is unknown, however, if stimulants would be of benefit for memory and thinking problems due to epilepsy.
- Trial name
- NCT04419272
- Testing
- Methylphenidate
- Where
- 4 sites in United States
- Volunteers
- 226 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Alzheimer s Disease
Deep Cervical Lymphovenous Anastomosis for Severe Alzheimer's Disease
Alzheimer's disease (AD) is a severe neurodegenerative disease with heavy social burden. Current drugs cannot reverse disease progression.
- Trial name
- DCLVA-AD (NCT07669272)
- Testing
- Deep Cervical Lymphovenous Anastomosis, Routine Treatment
- Where
- China
- Volunteers
- 59 people
- Sponsor
- Southwest Hospital, China
Hypertension, Condition
Adaptive Cognitive Training on Cognitive Function in Elderly Hypertension Patients in the Community
Objective A growing body of evidence supports hypertension as a risk factor for cognitive decline. Hypertension is significantly associated with accelerated cognitive decline, poorer cognitive function, and mild cognitive…
- Conditions
- Hypertension, Condition, Aging
- Trial name
- NCT06512922
- Testing
- adaptive cognitive training
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Peking University
Postpartum Depression
Postpartum 1-Day CBT Pilot Study (Türkiye)
This pilot randomized controlled trial aims to evaluate the feasibility, acceptability, and preliminary effects of a culturally adapted, one-day online Cognitive Behavioral Therapy (CBT)-based group workshop for women with…
- Trial name
- NCT07267702
- Testing
- One-Day Online CBT-Based Workshop
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Marmara University
Irritable Bowel Syndrome, Abdominal Pain
Online Social Learning Program for Parents With Irritable Bowel Syndrome: Raising Resilient Children
The goal of this clinical trial is to test efficacy of the REACH program in parents with irritable bowel syndrome (IBS) and their young children.
- Trial name
- REACH (NCT05730491)
- Testing
- Social Learning and Cognitive Behavioral Therapy (SLCBT), Attention Education Control
- Where
- United States
- Volunteers
- 460 people
- Sponsor
- Seattle Children's Hospital
Attention Deficit Hyperactivity Disorder (ADHD)
Cognitive-Motor Training With the DextEgg in Children With ADHD
Attention Deficit Hyperactivity Disorder (ADHD) is frequently accompanied by deficits in executive functions and fine motor skills, which affect daily activities, academic performance, and health-related quality of life.
- Trial name
- ADHD DextEgg (NCT07913997)
- Testing
- Cognitive-motor DextEgg training, Motor-only DextEgg training
- Volunteers
- 50 people
- Sponsor
- Manuela Pastore-Wapp
Affective Disorders, Rumination
Study on the Effectiveness of Journaling as an add-on to Cognitive Behavioral Therapy
The aim of the present study is to examine the effects of keeping a therapy journal (journaling) on the effectiveness of cognitive behavioral therapy (CBT).
- Conditions
- Affective Disorders, Rumination, Childhood Trauma, Eating Disorder
- Trial name
- NCT06863909
- Testing
- Journaling, Treatment as Usual (TAU)
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- University Hospital Tuebingen
Parkinson Disease, Cognitive Deficit in Attention
The Effect of Different Types of Focus Instructions in Parkinson's Rehabilitation
Parkinson's disease is the most common progressive neurodegenerative movement disorder. Common movement impairments in Parkinson's include balance and walking difficulties.
- Conditions
- Parkinson Disease, Cognitive Deficit in Attention, Feedback, Psychological, Gait, Festinating
- Trial name
- NCT06615115
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Bahçeşehir University
Cognitive Training, Functional Core Stability Training
Effect of Functional Core Stability Training or Cognitive Training on Balance and Postural Control in Chronic Ankle Instability
The purpose of the study is to investigate dynamic core stability training versus cognitive training on balance, functional performance, postural control, ankle instability scores, ankle dorsiflexion range of motion, and mental…
- Conditions
- Cognitive Training, Functional Core Stability Training, Balance; Distorted, Postural Control
- Trial name
- NCT07283276
- Testing
- strengthening exercises, Balance training, Functional core training
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Cairo University
Narcolepsy, Narcolepsy Type 1
Decreasing Nightmares in Adults With Narcolepsy
The purpose of this clinical trial is learn whether a behavioral (non-medication) treatment can reduce nightmares in adults with narcolepsy. All participants will receive the treatment and will complete three assessments.
- Conditions
- Narcolepsy, Narcolepsy Type 1, Narcolepsy With Cataplexy, Narcolepsy Without Cataplexy
- Trial name
- DAWN (NCT06383806)
- Testing
- Imagery Rehearsal Therapy (IRT)
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Utah