Clinical trials: Cognitive Disability
Cerebral Palsy, Cerebral Palsy (CP)
Assessing Intellectual and Motor Outcomes in High-risk Infants
Cerebral palsy (CP) is a condition when a baby has a brain injury that affects their movement and muscle tone. Some people with CP can have other developmental issues, like learning impairments, but many do not and have isolated…
- Conditions
- Cerebral Palsy, Cerebral Palsy (CP), Cerebral Palsy Children, High-risk Infants
- Trial name
- AIM-High (NCT06857539)
- Where
- 4 sites in Ireland
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University College Cork
Mild Intellectual Disability, Borderline Intellectual Functioning
Intervention Utilizing a Computerized Cognitive Rehabilitation Program (D-kit/EF1)
The goal of this exploratory clinical trial is to test the effects of the computerized cognitive rehabilitation program (D-kit/EF1) for children with borderline intellectual functioning or mild intellectual disability after its…
- Trial name
- NCT05933005
- Testing
- D-kit/EF1
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of California, San Francisco
PARKINSON DISEASE (Disorder)
Improving Functional Disability and Cognition in Parkinson Disease: Randomized Controlled Trial
The study design was a parallel-group randomized trial with equal randomization. Recruitment and enrollment were conducted between June 2012 and January 2013. At base-line, clinical, cognitive and functional data was collected.
- Trial name
- NCT02118480
- Testing
- cognitive remediation program: REHACOP, Occupational Therapy
- Where
- Spain
- Volunteers
- 44 people
- Sponsor
- University of Deusto
Strategy Training, Attention Control
Adapting Daily Activity Performance Through Strategy Training
Individuals with cognitive impairments after stroke sustain significant disability in their daily tasks, and account for a significant proportion of stroke-related healthcare costs.
- Trial name
- ADAPTS (NCT01934621)
- Testing
- Strategy Training, Attention Control
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- University of Pittsburgh
Multiple Sclerosis
Propionic Acid for Multiple Sclerosis: Safety and Benefits
The purpose of this study is to explore the long-term safety, tolerability, and clinical efficacy of propionic acid as an add-on therapy in multiple sclerosis (MS).
- Trial name
- Pro-MADAI (NCT07595081)
- Testing
- Propionic acid 1000 mg capsule
- Where
- Austria
- Volunteers
- 22 people
- Sponsor
- Salzburger Landeskliniken
Post Operative Pain
Parent Nurse Controlled Analgesic in Pediatric Patients With Developmental Delay
The purpose of this study is to compare, the safety, efficacy and level of parent and nurse satisfaction with three methods of opioid administration post-operatively in children (4-18 years of age) with developmental delay.
- Trial name
- PNCA (NCT00743730)
- Testing
- Pain and standard side effect management for PNCA with basal method., Pain and standard side effect management with PNCA without basal, Pain and standard side effect management with IV on an as needed basis method.
- Where
- United States
- Volunteers
- 94 people
- Sponsor
- Medical College of Wisconsin
Motor Disorders, Cognitive Disability
Study of the Acceptability and Psychosocial Impact of Using a Telepresence Robot in the Living Space of Inpatients
This study focuses on the mobile robot assist device for tele-interaction: the "COVEALINK 2" robot. This telepresence robot is designed for remote use inside the home. It works with an Internet connection (Wifi or 4G).
- Trial name
- ROBOLINK-e (NCT04899830)
- Testing
- Telepresence robot
- Where
- 4 sites in France
- Volunteers
- 49 people
- Sponsor
- Association APPROCHE
Bipolar Disorder, Cognitive Impairment
Quetiapine XR for Cognitive and Functional Disability in Clinically Stable Patients With Bipolar Disorder
Quetiapine has been reported to have beneficial cognitive effects in several randomized controlled trials in schizophrenia. It has not yet been studied in bipolar disorder, but promising results from the use of extended release…
- Trial name
- NCT00746421
- Testing
- Quetiapine XR
- Where
- 2 sites in United States
- Volunteers
- 32 people
- Sponsor
- Emory University
Intellectual Disability
Motor and Cognitive Dual-task Gait Training Effect Functional Outcome in Intellectual Disability
To find out the comparative effects of motor and cognitive dual gait training on improving the balance control and mobility skills among intellectual disable patients.
- Trial name
- NCT05334498
- Testing
- Motor dual-task gait training, Cognitive dual-task gait training
- Where
- Pakistan
- Volunteers
- 54 people
- Sponsor
- Riphah International University
Asperger's Disorder, Mental Retardation
Cognitive Neuroscience of Autism Spectrum Disorders
Background: Autism spectrum disorders (ASDs) are a group of developmental disorders that affect communication, social interaction, and behavior.
- Conditions
- Asperger's Disorder, Mental Retardation, Children, Adult
- Trial name
- NCT01031407
- Where
- United States
- Volunteers
- 678 people
- Sponsor
- National Institute of Mental Health (NIMH)
Down Syndrome
Evaluating The Efficacy And Safety Of Donepezil Hydrochloride (HCl) (Aricept) In Treating Cognitive Dysfunction Exhibited By Children With Down Syndrome
The purpose of this study is to determine whether donepezil HCl is effective and safe in improving cognitive dysfunction exhibited by children and adolescents with Down syndrome (DS).
- Trial name
- NCT00570128
- Testing
- Donepezil HCl
- Where
- 31 sites in United States
- Volunteers
- 129 people
- Sponsor
- Eisai Inc.
Alzheimer's Disease, Down Syndrome
Multicenter Vitamin E Trial in Aging Persons With Down Syndrome
The purpose of this study is to determine the safety and effectiveness of 2,000 international units of Vitamin E (alpha tocopherol)on cognitive function of aging persons with Down syndrome.
- Trial name
- NCT01594346
- Testing
- Alpha-Tocopherol, Sugar Pill
- Volunteers
- 349 people
- Sponsor
- New York State Institute for Basic Research
Technology, Cognitive Impairments
Tablet-based Interactive Games in Elderly With Cognitive Impairment and Persons With Intellectual Disability
The study has 10 research questions regarding the cognitive training program and tablet-based interactive games: Primary study questions: 1.
- Conditions
- Technology, Cognitive Impairments, Intellectual Disability
- Trial name
- NCT05822596
- Testing
- Tablet-based interactive games experimental group intervention
- Where
- 5 sites in Hong Kong
- Volunteers
- 68 people
- Sponsor
- The University of Hong Kong
Disability Physical, Cognition
Immersive Virtual Reality and Physical Exercise on Cognitive and Functional Performance in Hospitalized Older Patients
This study will be conducted in a hospital in Spain to investigate how a special intervention using immersive virtual reality technology can benefit hospitalized older adults with difficulties in their daily functionality.
- Trial name
- MOTOMED (NCT06340282)
- Testing
- Virtual reality, multicomponent exercise
- Where
- Spain
- Volunteers
- 212 people
- Sponsor
- Fundacion Miguel Servet