Clinical trials: Cognitive Disability
Mild Cognitive Impairment
Facilitating Optimal Routines in Aging
Loss of cognitive abilities leading to Alzheimer's disease is progressive and destructive, leaving older adults disabled and unable to recall their past.
- Trial name
- ForAging (NCT03913637)
- Testing
- Strategy Training, Enhanced Usual Care
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- University of Pittsburgh
Ageing, Disability
The Beijing Longitudinal Disability Survey in Community Elderly
The goal of this observational study is to establish the prospective cohort of the Beijing Longitudinal Disability Survey in Community Elderly (BLINDSCE) to explore the high-risk factors and preventive interventions for…
- Conditions
- Ageing, Disability, Cognitive Impairment, Frailty
- Trial name
- BLINDSCE (NCT06863727)
- Where
- China
- Volunteers
- 1,962 people, healthy volunteers welcome
- Sponsor
- Xuanwu Hospital, Beijing
Autism Spectrum Disorders, Autism
Psychotherapy for Anxiety in Children With Autism Spectrum Disorder
Anxiety disorders affect 40 to 50% of children with autism spectrum disorders (ASD), contributing to substantial distress and impairment.
- Conditions
- Autism Spectrum Disorders, Autism, Asperger's Syndrome, Pervasive Developmental Disability - Not Otherwise Specified
- Trial name
- TAASD (NCT02028247)
- Testing
- Personalized Cognitive-behavioral therapy, Standard Practice Cognitive-behavioral therapy, Treatment as Usual
- Where
- United States
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Functional Disability, Dynapenia
Multicomponent Training on Functional and Cognitive Performance of Hospitalized Older People
The goal of this clinical trial is to determine whether a multicomponent physical exercise program improves functional and cognitive capacity in hospitalized older adults compared to the usual hospital care.
- Conditions
- Functional Disability, Dynapenia, Cognitive Decline
- Trial name
- NCT06682598
- Testing
- Multicomponent physical exercise training
- Where
- Brazil
- Volunteers
- 47 people
- Sponsor
- Federal University of Rio Grande do Sul
Technology, Cognitive Impairments
Tablet-based Interactive Games in Elderly With Cognitive Impairment and Persons With Intellectual Disability
The study has 10 research questions regarding the cognitive training program and tablet-based interactive games: Primary study questions: 1.
- Conditions
- Technology, Cognitive Impairments, Intellectual Disability
- Trial name
- NCT05822596
- Testing
- Tablet-based interactive games experimental group intervention
- Where
- 5 sites in Hong Kong
- Volunteers
- 68 people
- Sponsor
- The University of Hong Kong
Down Syndrome
Safety, Tolerability and Immunogenicity of ACI-24 Vaccine in Adults With Down Syndrome
The purpose of this study is to test in adults with Down Syndrome the safety, tolerability and immunogenicity of a vaccine, ACI-24.
- Trial name
- 3-Star (NCT02738450)
- Testing
- ACI-24 low dose, ACI-24 high dose
- Where
- 4 sites in United States
- Volunteers
- 20 people
- Sponsor
- AC Immune SA
Low Back Pain, Non Specific Chronic Low Back Pain
Comparative Effects of Cognitive Functional Therapy With Kinetic Control Training on Non-specific Low Back Pain
The goal of this clinical trial is to compare Cognitive Functional Therapy (CFT) with Kinetic Control Training (KCT) in participants with non-specific low back pain.
- Trial name
- LBP (NCT07282925)
- Testing
- Cognitive Functional Therapy, Kinetic Control Training
- Where
- Pakistan
- Volunteers
- 70 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Attention Deficit Hyperactivity Disorders, Developmental Delays
Cognitive Training for Attention Deficit Hyperactivity Disorder and Developmental Delays
To explore whether children with Attention Deficit Hyperactivity Disorder and developmental delays who receive cognitive training and conventional rehabilitation can improve executive function more than traditional rehabilitation…
- Trial name
- NCT06277440
- Testing
- cognitive training, active control
- Where
- Taiwan
- Volunteers
- 20 people
- Sponsor
- Taipei Medical University
Multiple Sclerosis
Cognitive Markers in Prodromal MS
The focus of this work is the evaluation of a measure of cognitive functioning- intra-individual variability (IIV) - derived from a computer-based continuous reaction time (RT) task (Cogstate) as an early marker of prodromal MS.
- Trial name
- NCT05543915
- Testing
- Active tDCS
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- NYU Langone Health
Alzheimer Disease and Related Dementias, Cognition
Home-Based Brain Stimulation for Motoric Cognitive Risk Syndrome
The objective of this study is to determine the effects of a 6-month, home-based personalized transcranial direct current stimulation (tDCS) intervention targeting the left dorsolateral prefrontal cortex on cognitive function…
- Conditions
- Alzheimer Disease and Related Dementias, Cognition, Mobility Disability
- Trial name
- TDCS4MCR (NCT06821568)
- Testing
- Personalized Transcranial Direct Current Stimulation (tDCS)
- Where
- 2 sites in United States, Israel
- Volunteers
- 128 people
- Sponsor
- Hebrew SeniorLife
Fragile X Syndrome (FXS), Autism Spectrum Disorder
Group CBT in Adolescents With Fragile X Syndrome and in Adolescents With Autism Spectrum Disorder
Fragile X Syndrome (FXS) is a rare genetic syndrome, caused by a mutation in the FMR1 gene located on the X chromosome. It is considered the leading hereditary cause of intellectual disability (ID) and the primary cause of Autism…
- Trial name
- NCT06677866
- Testing
- Cognitive behavioral therapy, Waiting List
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Bambino Gesù Hospital and Research Institute
Intellectual Disability
Motor and Cognitive Dual-task Gait Training Effect Functional Outcome in Intellectual Disability
To find out the comparative effects of motor and cognitive dual gait training on improving the balance control and mobility skills among intellectual disable patients.
- Trial name
- NCT05334498
- Testing
- Motor dual-task gait training, Cognitive dual-task gait training
- Where
- Pakistan
- Volunteers
- 54 people
- Sponsor
- Riphah International University
Deficits, Neurologic, Extreme Prematurity
SafeBoosC III Two-year Follow-up
The SafeBoosC-III 2 year follow up study will follow up on all patients randomised in the SafeBoosC-III clinical trial (NCT03770741).
- Conditions
- Deficits, Neurologic, Extreme Prematurity, Brain Damage
- Trial name
- NCT05134116
- Testing
- Treatment as usual + cerebral oximetry monitoring the first 72 hours of life
- Where
- Denmark
- Volunteers
- 1,601 people
- Sponsor
- Gorm Greisen
Physical Disability
Norwegian Psychomotor Physiotherapy in Patients With Long-lasting Musculoskeletal Pain.
The aim is to examine the effect of Norwegian Psychomotor Physiotherapy (NPMP) in employees with long-lasting musculoskeletal pain compared to employees receiving Cognitive Patient Education in combination with active individual…
- Trial name
- NPMP (NCT02482792)
- Testing
- Norwegian Psychomotor Physiotherapy, Cognitive Patient Education and PT
- Where
- Norway
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Tove Dragesund
Down Syndrome
Application of LLM Care and Related Affective Computing Systems on Persons With Special Needs
Down syndrome (DS) is a genetic disorder characterized by specific physical characteristics (muscle degeneration) and cognitive phenotype (neurodegeneration caused by gene-overexpression that has affected memory, language, and…
- Trial name
- dsLLM (NCT04390321)
- Testing
- LLMcare
- Where
- Greece
- Volunteers
- 46 people
- Sponsor
- Aristotle University Of Thessaloniki
Frailty
Prevention of Disability in the Frail Elderly Person Through an Innovative Customised and Multidimensional Training Programme
The goal of this clinical trial is to implement a personalized training program to prevent functional decline in frail subjects but not yet disable.
- Trial name
- PRAISE (NCT06377436)
- Testing
- Experimental training
- Where
- Italy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Milan
Neurodevelopmental Cognitive, Motor and Speech-language Disabilities
Assessment and Telerehabilitation of Cognitive and Motor Skills in Children With Neurodevelopmental Disabilities (Tablet Project)
The development and application of new technologies to support functional assessment and rehabilitation pathways for neurodevelopmental disabilities allow the evaluation and enhancement of cognitive, motor, and speech abilities…
- Trial name
- NCT06290297
- Testing
- Telerehabilitation VRRS
- Where
- Italy
- Volunteers
- 350 people
- Sponsor
- IRCCS Fondazione Stella Maris
Carpal Tunnel Syndrome, Carpal Tunnel
Social and Cognitive Factors in Carpal Tunnel Syndrome
Carpal tunnel syndrome (CTS) is a compressive peripheral neuropathy, characterized by pain, tingling sensation and paresthesia in the territory of the median nerve, symptoms modulated by psychosocial factors (eg, catastrophic…
- Trial name
- NCT05023603
- Testing
- self-report questionnaire
- Where
- 2 sites in Chile
- Volunteers
- 86 people
- Sponsor
- Hospital Clínico La Florida
Aphasia, Stroke
Brain-based Understanding of Individual Language Differences After Stroke
Strokes often cause a loss of communication ability, referred to as aphasia, as well as cognitive difficulties. Each stroke survivor has a unique pattern of strengths and weaknesses in communication and cognition, and a unique…
- Conditions
- Aphasia, Stroke, Alexia
- Trial name
- BUILD (NCT04991519)
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Borderline Intellectual Functioning (BIF), Intellectual Disability
Co-design of an AI Rehabilitation Program for Children With Borderline Intellectual Disorder
Co-design of an AI Rehabilitation Program for Children With Borderline Intellectual Disorder
- Trial name
- NCT07625592
- Testing
- Tablet-Based AI Cognitive and Language Rehabilitation Program
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Samsung Medical Center