Clinical trials: Cognitive Disorder Patients and Cognitive Assessment
Major Depressive Disorder
Effect of Physical Activity on Depressive Symptoms With a 5 Month Follow-up
The main objective of this study is to evaluate the effect of a 12 weeks adapted physical activity program (active walking) on depression by analyzing the dynamics of emotional and cognitive functioning.
- Trial name
- 2DPAP (NCT01995422)
- Testing
- Physical activity program
- Where
- France
- Volunteers
- 16 people
- Sponsor
- Laboratory Motricité, Interactions, Performance
Metastatic Brain Tumor, Cerebral Metastases
Impact of Cognitive Rehab and Physical Activity on Cognition in Patients With Metastatic Brain Tumors Undergoing RT
To determine the feasibility of processes and instruments with an overarching purpose to guide the design of a larger study. To determine the feasibility of individuals with metastatic brain tumor(s) to engage in physical…
- Trial name
- NCT03096431
- Testing
- Physical Activity, Cognitive rehabilitation
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Virginia Commonwealth University
Migraine
Trans-diagnostic Cognitive-behavioral Therapy for Treatment of Migraine
Migraine headache is one of the disabling conditions that may be associated with decreased quality of life, anxiety and depression.
- Trial name
- NCT03701477
- Testing
- Trans-diagnostic cognitive-behavioral therapy, General relaxation/stress management therapeutic session
- Where
- Iran
- Volunteers
- 20 people
- Sponsor
- Isfahan University of Medical Sciences
Traumatic Brain Injury (TBI)
Effect of Exercise Training on Physical, Cognitive, and Behavioral Function in People With TBI
Background: Traumatic brain injury (TBI) often causes problems with moving and balance, and thinking and emotions. Exercise can improve these things in people with other brain damage.
- Trial name
- NCT02504866
- Testing
- Vigorous exercise, Light to moderate exercise
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Cognitive Impairment
RIVastigmine In Vascular cognitivE Impairment
The study is a 24-week prospective, double blind, randomized, placebo-controlled pilot study of 9 mg / day Rivastigmine in patients with Vascular Cognitive Impairment Not Dementia (CIND) to evaluate efficacy, safety and…
- Trial name
- RIVIVE (NCT00669344)
- Testing
- Exelon (rivastigmine)
- Where
- Singapore
- Volunteers
- 50 people
- Sponsor
- Singapore General Hospital
Exercise, Metabolic Syndrome
Exercise Effects on Health Status in Patients With Severe Mental Illness
People with severe mental disorders have a mortality rate 2 to 3 times higher than that of the general population, largely due to the presence of comorbidities, with a predominance of cardiovascular disease.
- Conditions
- Exercise, Metabolic Syndrome, Mental Disorders, Severe, Severe Mental Disorder
- Trial name
- SMI01 (NCT05834309)
- Testing
- Physical exercise
- Where
- 2 sites in Spain
- Volunteers
- 100 people
- Sponsor
- Universidad Pública de Navarra
Colorectal Cancer
A Longitudinal Investigation of Cognitive Function in Colorectal Cancer Patients
This is a prospective, longitudinal, controlled study of cognitive function and fatigue in patients with apparently localized CRC treated with adjuvant or neoadjuvant chemotherapy.
- Trial name
- NCT01457287
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Alzheimer Disease, Mild Memory Disturbance
The MObile AssessMENT of Behavioral and Psychological Symptoms of Dementia in Amnestic MCI and AD (MOMENT) Study
The purpose of this research study is to learn whether it is possible and useful for caregivers to report behavioral or psychological symptoms of people with mild memory problems or Alzheimer's disease through a smartphone mobile…
- Conditions
- Alzheimer Disease, Mild Memory Disturbance, Mild Cognitive Impairment
- Trial name
- MOMENT (NCT04482036)
- Testing
- Mobile Phone Application Assessments, Standard Assessments
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Indiana University
Carotid Artery Stenosis, Image
Evaluation of Brain Health and Surgical Efficacy in Patients With Carotid Artery Stenosis
The purpose of this study is to explore the relationship between the recovery of cerebrovascular morphology and cognitive function before and after surgical treatment in patients with carotid artery stenosis and their…
- Trial name
- NCT05848921
- Testing
- magnetic resonance image, Neuropsychological scale
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Nanjing University of Traditional Chinese Medicine
Low Back Pain, Chronic Pain
Chronic Low Back Pain Rehabilitation in Primary Care: an RCT
The aim of this study is to evaluate the effectiveness and cost-effectiveness of a new primary care intervention "Back on Track" as compared to usual primary care in patients with non-specific chronic low back pain in which…
- Conditions
- Low Back Pain, Chronic Pain, Musculoskeletal Pain
- Trial name
- NCT02220543
- Testing
- Back on Track intervention, Primary care as usual
- Where
- 8 sites in Netherlands
- Volunteers
- 25 people
- Sponsor
- Maastricht University Medical Center
Autism Spectrum Disorder, Social Communication Disorder
To Evaluate the Efficacy and Safety of 'NDTx-01' in Patients With ASD or SCD
The purpose of this study is to demonstrate the superiority of the treatment of cognitive therapy software 'NDTx-01' compared to TAU (Treatment-As-Usual).
- Trial name
- NCT06446193
- Testing
- NDTx-01, TAU
- Where
- 5 sites in South Korea
- Volunteers
- 86 people
- Sponsor
- Neudive Inc.
Alzheimer's Disease, Dementia
A Study to Evaluate the Effects of MK-0249 and an Alzheimer's Disease Medication on Cognitive Function in Adults With Alzheimer's Disease (MK-0249-023)
This study will evaluate acute symptomatic improvements in cognitive performance in healthy elderly participants with mild-to-moderate Alzheimer's disease.
- Trial name
- NCT00874939
- Testing
- MK-0249 7.5 mg, MK-0249 25 mg, Donepezil 5mg
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Gynecologic Cancer, Frailty
Cognitive and Physical Frailty as Predictors of Decision Satisfaction in Geriatric Gynecologic Oncology
This prospective observational study aims to evaluate the association between preoperative cognitive function, measured by the Montreal Cognitive Assessment (MoCA), and physical frailty, assessed using the Clinical Frailty Scale…
- Conditions
- Gynecologic Cancer, Frailty, Cognitive Impairment, Geriatric Oncology
- Trial name
- GYNCOGFRAIL (NCT07085000)
- Testing
- No Intervention - Observational Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Izmir City Hospital
Mild Cognitive Impairment, Alzheimer Disease
Specialized Food Plan Based on Individual Physiological Comprehensive Body Assessments Accompanied With Cellular Repair Therapy to Decrease Inflammation Cognitively Impaired Patients
Diet plays a large role in inflammation, oxidative stress and cognition; however, every person's body type, resting metabolic rate, BMI, and inflammation levels vary.
- Trial name
- NCT03630419
- Testing
- Mito-Food Plan, Cellular Repair Therapy
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Perseverance Research Center, LLC
Chronic Heart Failure (CHF)
Efficacy and Safety of LCZ696 Compared to Valsartan on Cognitive Function in Patients With Chronic Heart Failure and Preserved Ejection Fraction
This study was a multi-center, randomized, double-blind, parallel group, active comparator trial designed to evaluate the overall effect of LCZ696 compared to valsartan on cognitive function as assessed by the CogState…
- Trial name
- PERSPECTIVE (NCT02884206)
- Testing
- LCZ696, Valsartan
- Where
- 135 sites in United States, Argentina and 18 more
- Volunteers
- 592 people
- Sponsor
- Novartis Pharmaceuticals
Cognition, Parkinson's Disease
Dual-Task Balance and Gait Training Combined With Cognitive Training in Parkinson's Patients
The aim of the study is to examine the effects of a structured, cognitive dimension-specific cognitive training combined with dual-task balance and gait training on balance, gait, and cognition in individuals with Parkinson's…
- Conditions
- Cognition, Parkinson's Disease, Gait Disorders, Neurologic, Balance Disorders
- Trial name
- NCT07213232
- Testing
- Core Stability Training, Dual-Task Balance and Gait Training, Cognitive Training
- Where
- Turkey (Türkiye)
- Volunteers
- 14 people
- Sponsor
- Gazi University
Schizophrenia Disorders, Treatment Resistant Hallucinations
Cognitive and Metacognitive Evaluation in VR-Based Avatar Therapy for Psychosis
This study aims to evaluate the relationship between cognitive, metacognitive and social cognition variables in patients with psychosis undergoing VR-based Avatar Therapy for the treatment of auditory hallucinations.
- Trial name
- Meta-VR-AVATAR (NCT07091344)
- Testing
- VR-Based Avatar Therapy with Cognitive and Metacognitive Assessments
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Fundació Sant Joan de Déu
Post-Acute COVID-19 Syndrome, Cognitive Impairment
Safety, Efficacy, and Dosing of VIX001 in Patients With Neurological Symptoms of Post Acute COVID-19 Syndrome (PACS).
The study, identified as VIX001-PACS-01, is a Phase 1, open-label, dose-escalation trial evaluating the safety, tolerability, preliminary efficacy, and dose effect of VIX001, an amniotic fluid product, in patients with Post-Acute…
- Conditions
- Post-Acute COVID-19 Syndrome, Cognitive Impairment, Neurological Complication
- Trial name
- NCT05947617
- Testing
- VIX001
- Volunteers
- 9 people
- Sponsor
- Neobiosis, LLC
Pseudohypoparathyroidism Type 1A, Albright Hereditary Osteodystrophy
Albright Hereditary Osteodystrophy: Natural History, Growth, and Cognitive/Behavioral Assessments
We, the researchers, are following the natural history of Albright hereditary osteodystrophy. We have found that growth hormone deficiency is very common in patients with pseudohypoparathyroidism type 1A, which falls under the…
- Conditions
- Pseudohypoparathyroidism Type 1A, Albright Hereditary Osteodystrophy, Pseudopseudohypoparathyroidism
- Trial name
- NCT00209235
- Testing
- Neurocognitive and psychosocial testing
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- Connecticut Children's Medical Center
Parkinson Disease, Cognition Disorder
The Role of EEG in Identifying Cognitive Changes in Parkinson's Disease
This study is a group controlled clinical trial. Parallel study, patients aged 40-80 years, with Parkinson disease. Twelve sessions, three times a week, for 30 minutes.
- Conditions
- Parkinson Disease, Cognition Disorder, EEG With Abnormally Slow Frequencies
- Trial name
- NCT06145776
- Testing
- tDCS + tredmill training (Standart trehab training), Cognitite-motor Dual Task Training (DT training)
- Where
- 2 sites in Brazil
- Volunteers
- 36 people
- Sponsor
- Federal University of Paraíba