Clinical trials: Cognitive Disorder Patients and Cognitive Assessment
Stroke, Ischemic Stroke
Detecting and Predicting Post-stroke Cognitive Impairment Using the Oxford Cognitive Screen
Cognitive problems are common after a stroke and must be identified early so that rehabilitation can be initiated to improve outcome.
- Conditions
- Stroke, Ischemic Stroke, Hemorrhagic Stroke, Intracerebral, Cognitive Dysfunction
- Trial name
- OCS-PRECISE (NCT07897916)
- Where
- 2 sites in Denmark
- Volunteers
- 180 people
- Sponsor
- University of Copenhagen
Bipolar Disorder, Cognitive Impairment
Cognitive Stimulation for Elderly Bipolar Patients
Age is a major risk factor for the development of cognitive disorders and neurodegenerative pathologies. Cognitive disorders during the phases of bipolar disease are known to exist, and alterations increase significantly after…
- Conditions
- Bipolar Disorder, Cognitive Impairment, Age-related Cognitive Decline
- Trial name
- TONIC (NCT04184375)
- Testing
- cognitive stimulation
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Groupe Hospitalier de la Rochelle Ré Aunis
Cognitive Impairment
Evaluation of the Effect of Cooled Haemodialysis on Cognitive Function in Patients Suffering With End-stage KD
The Investigators aim to perform a feasibility study that will inform the development of a definitive, fully powered, randomised, controlled clinical trial in the future.
- Trial name
- E-CHECKED (NCT03645733)
- Testing
- Lower Temperature Group
- Where
- United Kingdom
- Volunteers
- 90 people
- Sponsor
- Heart of England NHS Trust
Multiple Sclerosis
Noninterventional Study Assessing Cognitive Function and Physical Activity in People With Multiple Sclerosis
Study assessing cognitive function and physical activity in people with relapsing remitting multiple sclerosis.
- Trial name
- CogniPlus (NCT01491100)
- Testing
- Interferon beta-1b (Betaseron, BAY86-5046)
- Where
- 17 sites in Albania, Algeria and 15 more
- Volunteers
- 1,085 people
- Sponsor
- Bayer
Multiple Sclerosis, Relapsing-Remitting
An Observational Study to Evaluate Quality of Life (QoL) and Influence of Cognitive Status on QoL in Patients With Relapsing-Remitting Multiple Sclerosis (RRMS) During 2 Years Treatment With Rebif New Formulation (RNF)
This is a prospective, non-interventional, multicenter study to evaluate quality of life (QoL) and influence of cognitive status on QoL in subjects with relapsing-remitting multiple sclerosis (RRMS) during two years of treatment…
- Trial name
- MusiClock (NCT01110993)
- Where
- Poland
- Volunteers
- 65 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Mild Cognitive Impairment, Walking
Impact of a Multicomponent Exercise Program on Cognitive and Functional Outcomes in Patients With Mild Cognitive Impairment
The goal of this randomised clinical trial is to investigate the effectiveness of an innovative therapeutic exercise program emphasizing in dual-task exercises in people with amnestic Mild Cognitive Impairment.
- Conditions
- Mild Cognitive Impairment, Walking, Balance, Cognition
- Trial name
- MExeProMCI (NCT07334392)
- Testing
- Innovative therapeutic exercise program, Therapeutic exercise program, Flyer
- Where
- Greece
- Volunteers
- 45 people
- Sponsor
- University of Patras
Stroke
Exercise the Mind and Brain. A Multimodal Intervention in Stroke
The main objective of MindFit Project is to develop an evidence-based multimodal investigation of combined non-pharmacological strategies in chronic stroke patients and clarify the neuroplasticity mechanisms underlying the…
- Trial name
- Mindfit (NCT04759950)
- Testing
- Multicomponent Physical Activity Program, Mindfulness-Based Stress Reduction Program, Computerized Cognitive Training
- Where
- Spain
- Volunteers
- 141 people
- Sponsor
- University of Barcelona
COPD, Cognitive Impairment
Investigation of Square Step Exercise Applied by Telerehabilitation in Chronic Obstructive Pulmonary Disease Patients
COPD is a progressive disease associated with systemic inflammation, with many extrapulmonary outcomes such as cognitive impairment.
- Conditions
- COPD, Cognitive Impairment, Balance; Distorted
- Trial name
- COPD (NCT04841005)
- Testing
- The Square-Step Exercise Training, Strengthening Exercise Training
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Abant Izzet Baysal University
Post-stroke Disorders
"Cognitive, Motor and Sleep Evaluation in Patients With Ischemic Stroke of Basal Ganglia After Thrombectomy"
The goal of this interventional study is to learn about the clinical outcomes of acute ischemic stroke treated with mechanical thrombectomy resulting in a selective ischemia of the basal ganglia.
- Trial name
- CMS - SBGT (NCT05878002)
- Testing
- polysomnography
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Elderly, Alzheimer Disease
Effects of 3-Month Melatonin Treatment on Regional Cerebellar Structure and Blood Biomarkers in Alzheimer's Disease Spectrum
The goal of this clinical trial is to explore and verify the preventive effects of melatonin on the progression of Alzheimer's disease.
- Conditions
- Elderly, Alzheimer Disease, Melatonin, Cognitive Decline
- Trial name
- NCT06756828
- Testing
- Melatonin, Cognitive behavioral therapy group for insomnia
- Volunteers
- 40 people
- Sponsor
- Saint Vincent's Hospital, Korea
Prostate Cancer, Prostate Neoplasm
Robotic-arm Assisted 68 Ga PSMA PET/CT Guided Prostate Biopsy Versus MR Directed Cognitive Fusion TRUS Guided Prostate Biopsy (PROBIOP)
The present study aimed to compare the diagnostic accuracy, radiation exposure, complication rates between 68Ga-PSMA PET/CT guided robotic arm assisted prostate biopsy and MRI directed TRUS guided prostate biopsy in PIRADS 4/5…
- Trial name
- PROBIOP (NCT05137561)
- Testing
- PSMA PET guided prostate biopsy, MRI directed TRUS guided prostate biopsy
- Where
- India
- Volunteers
- 217 people, healthy volunteers welcome
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Mild Cognitive Impairment, Aortic Stenosis
Prospective Evaluation of Neurocognition in Patients Undergoing Transcatheter Aortic Valve Replacement
This trail is for patients with mild cognitive impairment (MCI) who are receiving a transcatheter aortic valve replacement (TAVR).
- Trial name
- Neurcog TAVR (NCT05614986)
- Testing
- 5 minute Montreal Cognitive Assessment (mini MoCA)
- Where
- 4 sites in United States
- Volunteers
- 81 people
- Sponsor
- Baylor Research Institute
Focal Brain Injury, Cognition
Cognitive Function Assessment in Patients With Focal Brain Injury
This research relates to the study of cognitive deficits related to various focal brain lesions and their localizations in the brain.
- Trial name
- LESCOG (NCT04182087)
- Testing
- Cognitive tasks
- Where
- France
- Volunteers
- 400 people
- Sponsor
- University Hospital, Grenoble
Stroke
Cognitive Assessment for Stroke Patients: Reproductibility and Validity Study
After a CVA, all of the cognitive functions can be affected and analysed, but the presence of a language disorder may considerably hamper the evaluation of other functions.
- Trial name
- Casper (NCT01904799)
- Testing
- Cognitive Assessment test
- Where
- France
- Volunteers
- 263 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Covid19, Respiratory Disease
Post COVID19 Functional and Cognitive Assessments
The main objective of the proposed study is to evaluate the impact of coronavirus (2019-nCoV), hereafter COVID -19, on patients' loss of functional capacity after completion of hospital treatment.
- Conditions
- Covid19, Respiratory Disease, Walking, Difficulty, Cognitive Decline
- Trial name
- PostCovidZRS (NCT04860206)
- Where
- Slovenia
- Volunteers
- 43 people
- Sponsor
- Science and Research Centre Koper
Schizophrenia
Compare the Effect on Cognitive Functioning of Two Formulations of Seroquel, Seroquel XR and IR in Patients With Stable Schizophrenia
This will be a phase IV 20 -32 day prospective, double blind, double-dummy, randomised crossover study that will evaluate the effect of quetiapine XR and quetiapine IR on cognitive performance in patients with schizophrenia…
- Trial name
- eXtRa (NCT01213836)
- Testing
- Seroquel XR- quetiapine fumarate extended release, Seroquel IR - quetiapine fumarate
- Where
- 20 sites in Austria, Denmark and 3 more
- Volunteers
- 75 people
- Sponsor
- AstraZeneca
Multiple Sclerosis
Cognitive Functions in Patients With Multiple Sclerosis
Approximately 65% of multiple sclerosis (MS) patients appear to have problems in their cognitive function. Long-term memory is one of the most frequently affected functions in MS patients.
- Trial name
- NCT03594357
- Where
- Turkey (Türkiye)
- Volunteers
- 137 people, healthy volunteers welcome
- Sponsor
- Gazi University
Myotonic Dystrophy 1
Evaluation of Cognitive Functions in 20 Patients With Type 1 Myotonic Dystrophy With Virtual Reality Approach
Type 1 myotonic dystrophy (MD1) is a genetic and hereditary disease that primarily affects muscle tissue, resulting in myotonia (difficulty relaxing after contraction) and atrophy (progressive muscle weakening with decreased…
- Trial name
- GoodDiagNMD (NCT06270186)
- Testing
- Type 1 myotonic dystrophy
- Sponsor
- Centre Hospitalier Universitaire de Nice
Quality of Life, Aortic Valve Stenosis
Frailty and Cognitive Function Assessment of TAVI Patients
Aortic stenosis (AS) is the most common valve disease among the adult population, in the majority of the cases it only requires treatment in advanced age.
- Conditions
- Quality of Life, Aortic Valve Stenosis, Heart Valve Disease
- Trial name
- NCT02650388
- Testing
- Cognitive fuction, quality of life
- Where
- Hungary
- Volunteers
- 100 people
- Sponsor
- Hungarian Institute of Cardiology
Fibromyalgia
The Effect of Digital Cognitive Behavioural Therapy for Insomnia on Physical Activity in Fibromyalgia
The goal of this clinical trial is to learn if a digital sleep therapy program (digital Cognitive Behavioural Therapy for Insomnia or dCBT-I) works to improve quality of life and movement in adults with fibromyalgia who also have…
- Trial name
- PainLESS-2 (NCT07465991)
- Testing
- Digital Cognitive Behavioural Therapy for Insomnia, Sleep Hygiene Education Materials
- Where
- 2 sites in United Kingdom
- Volunteers
- 142 people
- Sponsor
- University of Oxford