Clinical trials: Cognitive Disorder Patients and Cognitive Assessment
Functional Impairment, Cognitive Impairment
Functional and Cognitive Impairment Prevention for Elderly Hospitalized Patients
The current model of care for the hospitalized elderly patients has been conditioned by many factors unrelated to the disease process that caused the hospitalization and usually worsen the outcome of hospitalization…
- Conditions
- Functional Impairment, Cognitive Impairment, Elderly
- Trial name
- NCT02300896
- Testing
- Group-based exercise training during hospitalization
- Where
- Spain
- Volunteers
- 370 people
- Sponsor
- Fundacion Miguel Servet
Parkinson Disease
The Effect of Dual Tasking on Physical and Cognitive Functions in Patients With Parkinson Disease
The ability of performing multi-tasking procedures is impaired in patients with Parkinson's disease. In this study, our goal was to detect the effects of dual-task training with treadmill training on walking and balance and to…
- Trial name
- NCT03902990
- Testing
- Dual task, Treadmill Training, Standard exercise programme
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Istanbul University
Alzheimer's Disease
Safety and Efficacy of MEM 1003 Versus Placebo in Patients With Mild to Moderate Alzheimer's Disease
The purpose of this study is to determine in a 12-week treatment study if MEM 1003 is a safe and effective treatment for patients with mild to moderate Alzheimer's disease.
- Trial name
- NCT00257673
- Testing
- MEM 1003
- Where
- 57 sites in United States
- Volunteers
- 183 people
- Sponsor
- Memory Pharmaceuticals
Inguinal Hernia Unilateral, Delayed Neurocognitive Recovery
Preemptive IV Ibuprofen for Neurocognitive Recovery and Analgesic Needs After Inguinal Hernia Surgery
The primary objective of this study is to evaluate the effects of preemptive intravenous ibuprofen administration on delayed neurocognitive recovery (dNCR), postoperative pain management, and the overall quality of recovery in…
- Conditions
- Inguinal Hernia Unilateral, Delayed Neurocognitive Recovery, Postoperative Pain, Neuroinflammation
- Trial name
- IBU-COG (NCT07424001)
- Testing
- Ibuprofen (400 mg x 4)
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Mehmet Çiğdem
Alzheimer Disease
A Trial to Evaluate the Efficacy and Safety of PQ912 in Patients With Early AD
This is a Phase 2A multi-center, randomized, double blind, placebo-controlled, parallel group study of varoglutamstat, with a stage gate to Phase 2B.
- Trial name
- VIVA-MIND (NCT03919162)
- Testing
- PQ912
- Where
- 22 sites in United States
- Volunteers
- 112 people
- Sponsor
- Vivoryon Therapeutics N.V.
Breast Cancer, Gynecologic Cancer
Clinical Investigation of the Effects of Semiconductor Embedded Therapeutic Garments on Cancer-related Cognitive Impairment in Breast and Gynecological Cancer Patients
The purpose of this study is to assess the feasibility of a wearing semiconductor embedded headband for cancer-related cognitive impairment in patients with breast or gynecological cancers.
- Conditions
- Breast Cancer, Gynecologic Cancer, Cancer-related Cognitive Difficulties
- Trial name
- HEADBAND (NCT07173101)
- Testing
- Semiconductor embedded headband
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of Utah
Alzheimer's Disease
Effectiveness of Florbetapir (18F) PET Imaging in Changing Patient Management and the Relationship Between Scan Status and Cognitive Decline
This study is designed to determine the effectiveness of florbetapir (18F) in changing patient management and to evaluate the association between scan status and cognitive decline.
- Trial name
- NCT01703702
- Testing
- florbetapir (18F)
- Where
- 57 sites in United States, France and 1 more
- Volunteers
- 641 people
- Sponsor
- Avid Radiopharmaceuticals
Diabetes Mellitus, Type 1
Advanced Hybrid Closed Loop System (AHCL) in Older Patients With Type 1 Diabetes Mellitus
The trial is a randomized controlled, parallel group design study. Patients will be followed up during approximatively 12 months.
- Trial name
- NCT06236256
- Testing
- MiniMed™ 780G Advanced Hybrid Closed Loop (AHCL) system, MDI/CSII
- Where
- Israel
- Volunteers
- 42 people
- Sponsor
- Sheba Medical Center
Insomnia, Schizophrenia
Insomnia in the Patient With Schizophrenic Disorder: Evaluation of a CBT and Psychoeducational Intervention
The study aims to evaluate the efficacy of a cognitive behavioural and psychoeducational intervention in patients with insomnia and diagnosed with a schizophrenic disorder.
- Trial name
- NCT05115604
- Testing
- cognitive behavioural intervention
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- David Batalla-Martin
Idiopathic Parkinson Disease
Effects of Sensory-Motor Integration Training in Patients with Idiopathic Parkinson's Disease
The goal of this single blind randomized controlled trial is to investigate the effect of sensory-motor integration training on cognitive functions, balance and gait in patients with Parkinson Disease? The main questions it aims…
- Trial name
- NCT06390163
- Testing
- Sensory-Motor Integration Training
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Hacettepe University
Complex Regional Pain Syndromes
Physical and Psychological Changes in CRPS Patients Undergoing Multimodal Rehabilitation
The goal of this clinical trial is to learn about cognitive changes during rehabilitation in CRPS patients. The main questions it aims to answer are: What are the cognitive changes in CRPS? Do cognitive functions change during…
- Trial name
- NCT05696587
- Testing
- Multimodal rehabilitation
- Where
- Poland
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- National Institute of Geriatrics, Rheumatology and Rehabilitation, Poland
High Intensity Interval Training, Heart Failure
Effects of Upper Extremity Low Volume HIIT in Heart Failure
This study was planned to investigate the effects of upper extremity low-volume high-intensity interval training (LV-HIIT) on physical and cognitive function in patients with heart failure with preserved ejection…
- Conditions
- High Intensity Interval Training, Heart Failure, Exercises
- Trial name
- NCT06754475
- Testing
- Low-volume, high-intensity interval training, Standart medical treatment
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Tarsus University
Corona Virus Infection, Covid19
Evaluation of Physical and Functional Status in Patients With COVID-19 in Long Term
The reason the investigators want to do this research; Especially after Covid-19 infection, no research has been found on functional status in the long term.
- Trial name
- NCT04836767
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Alzheimer's Disease
Evaluation of Safety & Tolerability of Multiple Dose Regimens of CHF 5074 and Exploration of Effects on Potential Markers of Clinical Efficacy in Patients With Mild Cognitive Impairment - Prolonged Open Label Extension Phase
The purpose of the study is to evaluate the safety and tolerability of ascending oral doses of CHF 5074 after prolonged administration to patients with mild cognitive impairment.
- Trial name
- CT04 POLEP (NCT01602393)
- Testing
- CHF 5074 1x, CHF 5074 2x, CHF 5074 3x
- Where
- 5 sites in United States, Italy
- Volunteers
- 51 people
- Sponsor
- Chiesi Farmaceutici S.p.A.
Cognitive Dysfunction, Cognitive Aging
Three-month Chan-Chung Qigong Improves Physical Function Performance and Quality of Life
The purpose of this study aimed to evaluate the effect of the three-month Chan-Chung qigong program in improving physical functional performance and quality of life in patients with mild to moderate cognitive impairments.A…
- Conditions
- Cognitive Dysfunction, Cognitive Aging, Grip, Exercise Training
- Trial name
- NCT04904991
- Testing
- Chan-Chuang qigong
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Tri-Service General Hospital (TSGH)
Diabetic Ketoacidosis
Diabetic Ketoacidosis: Brain Morphology and Cognition
The purpose of this study is to assess brain and memory changes in patients with uncontrolled diabetes (a condition called diabetic ketoacidosis (DKA))
- Trial name
- DKA-Cog (NCT02443415)
- Where
- 2 sites in United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Emory University
COVID-19, Quality of Life
Long-term Quality of Life and Prognostic Factors in Severe COVID-19 Patients and Their Relatives
This is a prospective cohort study with multicenter retrospective data collection (CHR Metz-Thionville, Hôpital Mercy and Hôpital Bel Air).
- Conditions
- COVID-19, Quality of Life, Posttraumatic Stress Disorder, Cognitive Impairment
- Trial name
- QUALICOVID (NCT05520047)
- Testing
- COVID19-severe Patient, family of COVID19-severe Patient
- Where
- France
- Volunteers
- 800 people
- Sponsor
- Centre Hospitalier Régional Metz-Thionville
Cognitive Change, Total Knee Anthroplasty
Early Cognitive Changes After General Versus Spinal Anesthesia in Older Adults Undergoing Total Knee Arthroplasty
This prospective observational study investigated early postoperative cognitive changes in older adults undergoing elective total knee arthroplasty under general or spinal anesthesia.
- Trial name
- NCT07860593
- Testing
- General Anesthesia, Spinal Anesthesia with Bupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Haseki Training and Research Hospital
Alzheimer Disease
Efficacy and Safety of Temporal Interference Stimulation on Cognitive Function in Patients With Early-Stage Alzheimer's Disease
This study aims to investigate the efficacy and safety of a novel non-invasive brain stimulation technique-Temporal Interference Stimulation (TIS)-in patients with early-stage Alzheimer's disease.
- Trial name
- NCT07543094
- Testing
- Temporal Interference Stimulation
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Ruijin Hospital
Hypertension, Type 2 Diabetes Mellitus (T2DM)
Community-Empowerment and Environmental Enrichment-based Co-management (CEEEC) Model and Mechanisms for Improving Health of Older Stroke Patients With Multimorbidity
This study is a cluster randomized controlled trial with a 2×2 factorial design conducted in community health centers in Kunshan, Wuhan and Shanghai, China.
- Conditions
- Hypertension, Type 2 Diabetes Mellitus (T2DM), Multimorbidity, Stroke
- Trial name
- CEEEC (NCT06975501)
- Testing
- Exercise Intervention, Cognitive Intervention
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Duke Kunshan University