Clinical trials: Cognitive Disorder Patients and Cognitive Assessment
Cystic Fibrosis
Comparison of Physical Activity, Exercise Capacity, Quality of Life, Cognitive Function and Coronavirus Phobia Levels of Adult Cystic Fibrosis Patients With Healthy Individuals With Telerehabilitation
The purpose of this study was to evaluate physical activity, exercise capacity, quality of life, cognitive status level and coronavirus phobia level of adult cystic fibrosis patients and compare with the findings of healthy…
- Trial name
- NCT04673331
- Testing
- exercise capacity
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Alzheimer Disease
A Study of LY3002813 in Participants With Memory Damage Due to Alzheimer's Disease (AD) or AD
The study will evaluate the effect of LY3002813 on brain scans. The study will evaluate the safety of LY3002813 by looking at adverse events (side effects). The study will also look at the effect the body has on LY3002813.
- Trial name
- NCT02624778
- Testing
- LY3002813
- Where
- 9 sites in United States, Japan
- Volunteers
- 61 people
- Sponsor
- Eli Lilly and Company
Cognitive Side Effects of Cancer Therapy, Depression
Typhoid Vaccine in Testing Response to Immune Stress in Patients With Stage I-IIIA Breast Cancer
This randomized clinical trial uses an inactive typhoid vaccine to briefly stimulate an immune response in patients with stage I-IIIA breast cancer who received primary cancer treatment and studies whether patients' fitness…
- Conditions
- Cognitive Side Effects of Cancer Therapy, Depression, Recurrent Breast Carcinoma, Stage IA Breast Cancer
- Trial name
- IMPACT (NCT02415387)
- Testing
- typhoid vaccine
- Where
- United States
- Volunteers
- 172 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Alzheimer Disease
Comparative Efficacy, Safety, and Tolerability of Rivastigmine 10 and 15 cm^2 Patch in Patients With Alzheimer's Disease (AD) Showing Cognitive Decline
The purpose of this study was to support the optimal use of rivastigmine patch in long-term treatment of Alzheimer's Disease in patients demonstrating functional and cognitive decline at the target maintenance dose of…
- Trial name
- NCT00506415
- Testing
- Rivastigmine 5 cm^2, Rivastigmine 10 cm^2, Rivastigmine 15 cm^2
- Where
- 145 sites in United States, Canada and 5 more
- Volunteers
- 1,584 people
- Sponsor
- Novartis Pharmaceuticals
Schizophrenia Cognition Autobiographical Memory Cognitive Remediation, SCHIZOPHRENIA 1 (Disorder)
Acceptability and Efficacy of Group Reminiscence Intervention in a Sample of Patients With Schizophrenia
The study aimed to test whether group reminiscence intervention for inpatients with schizophrenia is feasible, acceptable and preliminary effective.
- Conditions
- Schizophrenia Cognition Autobiographical Memory Cognitive Remediation, SCHIZOPHRENIA 1 (Disorder), Hospitalized Adult Patients
- Trial name
- NCT07512843
- Testing
- Group reminiscence therapy
- Where
- Jordan
- Volunteers
- 38 people
- Sponsor
- The Hashemite University
Perioperative Care
Improvement of Perioperative Care of Elderly Patients
The focus of this study is the development of a perioperative treatment concept for elderly patients, based on individual necessities and risk factors, aiming to improve patient outcome.
- Trial name
- PeriAge (NCT03325413)
- Testing
- Systematic inclusion of family members, Preoperative information, Physical and breathing exercises
- Where
- Germany
- Volunteers
- 310 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Heart Failure, Systolic, Heart Failure With Preserved Ejection Fraction
Virtual Visits to Optimize Research Trial Offerings to HF Patients
This pilot study seeks to understand if distance health technology with virtual visits hold the key to improving access for patients who wish to partake in clinical trials clearing barriers to enrollment.
- Trial name
- Optimize-HF (NCT04064541)
- Testing
- Virtual Visit
- Where
- United States
- Volunteers
- 94 people
- Sponsor
- The Cleveland Clinic
Cognitive Impairment, Haematological Malignancy
Cognitive Status Assessment In Elderly Patients With Active Treatment For Haematological Malignancies
BACKGROUND Neurocognitive symptoms have a high prevalence in cancer patients, resulting in a significant impact on daily life and tolerance to therapy.
- Conditions
- Cognitive Impairment, Haematological Malignancy, Chemo-brain
- Trial name
- NCT04673305
- Testing
- Cognitive Assessment, Cytokine dosage
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Ospedale San Carlo Borromeo
Schizophrenia
Cognitive Behavioral Therapy Added to Risperidone for Schizophrenia
This study evaluated whether cognitive behavioral therapy (CBT), when added to risperidone treatment, improves cognitive function and serum brain-derived neurotrophic factor (BDNF) levels in patients with schizophrenia.
- Trial name
- CBT-BDNF-SCZ (NCT07609953)
- Testing
- Risperidone 4 to 6 mg/day, Cognitive Behavioral Therapy
- Where
- Indonesia
- Volunteers
- 42 people
- Sponsor
- Hasanuddin University
Postoperative Cognitive Dysfunction, Delirium, Postoperative
Evaluation of the Predictive Impact of Serum S100B and S100B Polymorphisms on Postoperative Cognitive Dysfunction and Delirium
Postoperative cognitive disorders, including postoperative cognitive dysfunction (POCD) and postoperative delirium (POD), are common complications following surgery and anesthesia, particularly in vulnerable patient populations.
- Trial name
- NCT07509372
- Testing
- Perioperative Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 137 people
- Sponsor
- Ankara University
Cognitive Coping, Hemiplegia
Robotic Rehabilitation and Dual-Task Exercises in Hemiplegic Patients
The aim of this study was to investigate the effectiveness of dual-task exercises combined with robotic rehabilitation applied to post-stroke hemiplegia patients.
- Trial name
- NCT06709222
- Testing
- robotic rehabilitation, exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Uskudar University
Schizophrenia Disorders
Effect of AQW051 on Cognitive Function in Patients With Chronic Stable Schizophrenia
This PoC study is designed to assess the cognitive effects of doses of AQW051 in patients with chronic stable schizophrenia.
- Trial name
- NCT01163227
- Testing
- AQW051 2 mg (single and multiple doses), AQW051 15mg (single and multiple doses), AQW051 100mg (single dose), and 50mg (multiple doses)
- Where
- 2 sites in United States
- Volunteers
- 57 people
- Sponsor
- Novartis Pharmaceuticals
Alzheimer Disease
Neuropsychological and Neurophysiological Effects of Cognitive Stimulation in Patients With Alzheimer's Disease and Mild Cognitive Impairment
The present study aims to evaluate the effect of cognitive stimulation (CS) in participants with a diagnosis of moderate and mild Alzheimer's disease (AD) and mild cognitive impairment (MCI) compared to control subjects not…
- Trial name
- NCT03784183
- Testing
- Cognitive Stimulation (CS)
- Where
- Italy
- Volunteers
- 126 people
- Sponsor
- University of Roma La Sapienza
Hearing Loss, Hearing Loss, Sensorineural
Cochlear Implant Recipients: Comprehensive Longitudinal Evaluation
This study aims to assess hearing and speech perception, as well as quality of life, in deaf patients of all ages before and after cochlear implantation, and to explore differences across age groups and treatment subtypes…
- Conditions
- Hearing Loss, Hearing Loss, Sensorineural, Deafness, Cochlear Implantation
- Trial name
- CIRCLE (NCT07380269)
- Testing
- Cochlear Implantation
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Multiple Sclerosis
The Effect of Multiple-Task Training in Patients With Multiple Sclerosis
The Activities of Daily Living requires the ability to perform multiple activities at the same time, not just the motor or cognitive activity.
- Trial name
- NCT03512886
- Testing
- Multi-task training, Single task training
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people
- Sponsor
- Gazi University
Fibromyalgia
Cognitive Dysfunction in Fibromyalgia Patients
Fibromyalgia is a common rheumatologic disorder. Many patients complain of cognitive dysfunction as part of their symptoms. The investigators aim to assess this cognitive dysfunction through extensive neuro-cognitive testing.
- Trial name
- NCT01655537
- Where
- Israel
- Volunteers
- 25 people
- Sponsor
- Hadassah Medical Organization
Breast Cancer
Exercise and Cognitive (Brain) Function in Breast Cancer Patients Getting Chemotherapy After Breast Surgery
This study will primarily identify longitudinal associations between cardiorespiratory fitness (CRF) and cognitive function pre- (baseline) to post-chemotherapy (~3 months). This will be a prospective study of 50 BCS.
- Trial name
- NCT04616300
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- University of Toronto
GVHD, Chronic, GVHD - Graft-Versus-Host Disease
Psychiatric Status and Symptom Severity in Graft-versus-Host Disease (GvHD).
This prospective observational study evaluates the association between psychiatric status, GvHD-related symptom severity, and health-related quality of life in patients with graft-versus-host disease.
- Conditions
- GVHD, Chronic, GVHD - Graft-Versus-Host Disease, GVHD, Quality of Life
- Trial name
- Psych-GvHD (NCT07314892)
- Where
- Poland
- Volunteers
- 200 people
- Sponsor
- Medical University of Gdansk
Dementia Alzheimers, Mild Cognitive Impairment
Validation of a Novel Self-Administered Cognitive Assessment Tool (CogCheck) in Patients With Mild and Major Neurocognitive Disorder Predominantly Due to Alzheimer's Disease
Due to the demographical development, age-related diseases will drastically increase over the next decades. To face this healthcare challenge, early and accurate identification of cognitive impairment is crucial.
- Conditions
- Dementia Alzheimers, Mild Cognitive Impairment, Cognition Disorders, Neurocognitive Disorders
- Trial name
- CogCheck-MC (NCT03672279)
- Testing
- CogCheck
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- University Hospital, Basel, Switzerland