Clinical trials: Cognitive Disorders
Prostate Cancer, Prostate Neoplasm
Robotic-arm Assisted 68 Ga PSMA PET/CT Guided Prostate Biopsy Versus MR Directed Cognitive Fusion TRUS Guided Prostate Biopsy (PROBIOP)
The present study aimed to compare the diagnostic accuracy, radiation exposure, complication rates between 68Ga-PSMA PET/CT guided robotic arm assisted prostate biopsy and MRI directed TRUS guided prostate biopsy in PIRADS 4/5…
- Trial name
- PROBIOP (NCT05137561)
- Testing
- PSMA PET guided prostate biopsy, MRI directed TRUS guided prostate biopsy
- Where
- India
- Volunteers
- 217 people, healthy volunteers welcome
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Iron Status
The Relationship Between Iron Status, Cognitive Performance, Subjective Mood and Fatigue in Women of Reproductive Age.
Iron deficiency is the most prevalent nutritional deficiency worldwide with one in four estimated to be affected by iron deficiency anaemia.
- Trial name
- NCT04257669
- Where
- United Kingdom
- Volunteers
- 379 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Depression, Anxiety, Alcohol Abuse
Cognitive-Behavioral Therapy for Young Adult Lesbian, Gay and Bisexual: Transdiagnostic Minority Stress Approach
Background: LGB people experience a large number of anxiety and mood disorders, and risk behaviors than heterosexual (Marshall et al., 2011).
- Conditions
- Depression, Anxiety, Alcohol Abuse, Sexual Compulsivity, Unsafe Sex
- Trial name
- NCT03980873
- Testing
- ESTEEM (Effective Sikills to Empower Effective Men)
- Where
- Spain
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- University of the Basque Country (UPV/EHU)
Preterms at Risk for Developmental Disorders
CareToy - A Modular Smart System for Infants' Rehabilitation at Home Based on Mechatronic Toys
Stroke and other neurological conditions affect the population of infants in percentages that cannot be considered marginal. Preterm infants are the highest infants at risk for neurological damage.
- Trial name
- CareToy (NCT01990183)
- Testing
- CareToy, Standard Care
- Where
- 2 sites in Denmark, Italy
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- IRCCS Fondazione Stella Maris
Motoric Cognitive Risk Syndrome, Mild Cognitive Impairment
Pre-demential Motoric Cognitive Risk Syndrome in Ageing Subjects
The main aim of the study is to characterize and understand the pathological mechanisms underlying the motoric cognitive risk syndrome, which is a predictor of Alzheimer disease.
- Conditions
- Motoric Cognitive Risk Syndrome, Mild Cognitive Impairment, Alzheimer Disease, Dementia
- Trial name
- PRESAGE (NCT05640141)
- Testing
- MRI evaluation, Actimetry & IMU, Gait evaluation
- Where
- France
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Mild Cognitive Impairment
Evolving Methods to Combine Cognitive and Physical Training for Individuals With Mild Cognitive Impairment
This study aims to investigate and compare the intervention effects of combining exercise and cognitive training (either sequentially or simultaneously in a dual-task paradigm) in elderly with mild cognitive impairment.
- Trial name
- NCT02512627
- Testing
- Cognitive training, Physical exercise
- Where
- 9 sites in Taiwan
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Exercise Environment and Cognitive Performance in Older Adults
Outdoor vs. Indoor Exercises and Cognitive Functions in Older Adults
This observational, cross-sectional study aims to comparatively investigate the effects of outdoor versus indoor exercise environments on overall cognitive performance and its specific sub-domains (attention, memory, and…
- Trial name
- NCT07728786
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Muğla Sıtkı Koçman University
Multiple Sclerosis
Short and Long Term Multiple Outcomes in Persons With Multiple Sclerosis Treated by Fampridine.
This prospective monocentric open label trial was realized in the Laboratory of Clinical Functional Exploration of Movement at the University Hospital of Besancon.
- Trial name
- FAMPISEP (NCT02849782)
- Testing
- Fampridine
- Where
- France
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Physical Inactivity, Walking
Daily Goal Setting to Increase Everyday Physical Activity and Promote Cognitive Health in Midlife
The purpose of this study is to determine whether interaction with an adaptive Fitbit-based goal setting application can increase levels of everyday light intensity physical activity in middle-aged adults.
- Conditions
- Physical Inactivity, Walking, Cognitive Health, Self-regulation
- Trial name
- NCT05826379
- Testing
- Adaptive Daily Goal Setting, Interim Goal Prompt
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Huntington Disease
Benchmarking Integrated Care for People Living With Huntington's Disease in England
The survey and full study information can be accessed here: https://southampton.qualtrics.com/jfe/form/SV_8iEedDJZy4xaiI6 The goal of this anonymous survey is to benchmark integrated care from the perspective of service users in…
- Trial name
- Integrate-HD (NCT05828992)
- Testing
- No intervention administered
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Southampton
Shoulder Dystocia
TelesDystocia: Tele-Support vs. Cognitive Aid in Simulated Shoulder Dystocia
Shoulder dystocia is an unpredictable, time-critical obstetric emergency requiring immediate recognition and rapid execution of established maneuvers.
- Trial name
- TelesDystocia (NCT07772102)
- Testing
- Remote Tele-Support, Cognitive Aid
- Where
- Austria
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Obesity, Overweight
Effects of Cognitive Behavioral Therapy (CBT) on Weight Maintenance After Successful Weight Loss
The purpose of this study is to assess the effects of CBT after a successful weight loss by a comprehensive weight loss plan on weight maintenance in obese female adults.
- Trial name
- NCT02398253
- Testing
- CBT + Hypo-energetic Diet, Hypo-energetic Diet only
- Where
- Iran
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Novindiet Clinic
Iodine Deficiency, Goiter
The Effects of Iodized Salt on Cognitive Development in Ethiopia
Many school children in Ethiopia and their mothers are known to be iodine deficient. Prevalence in the Amhara region is around 29%.
- Conditions
- Iodine Deficiency, Goiter, Cretinism
- Trial name
- NCT01349634
- Testing
- Iodized salt
- Where
- Canada
- Volunteers
- 5,704 people, healthy volunteers welcome
- Sponsor
- McGill University
Healthy, Subjective Cognitive Decline (SCD)
Sleep Stimulation to Enhance Waste Clearance in the Brain
This study aims to examine whether multi-night closed-loop auditory stimulation (CLAS) during sleep can enhance waste clearance and memory consolidation in healthy adults and older adults with subjective cognitive decline or mild…
- Conditions
- Healthy, Subjective Cognitive Decline (SCD), Mild Cognitive Impairment (MCI), Alzheimer Disease (AD)
- Trial name
- NCT07051239
- Testing
- Closed-loop acoustic stimulation
- Where
- Belgium
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Erasme University Hospital
Mild Cognitive Impairment
iTBS rTMS in Mild Cognitive Impairment
The purposes of this research are to test whether it is feasible to administer a treatment protocol called intermittent theta burst stimulation (iTBS) repetitive transcranial magnetic stimulation (rTMS) in adults with mild…
- Trial name
- NCT05327257
- Testing
- iTBS rTMS
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Maria I. Lapid, M.D.
HIV, Aging
The Targeted Neurocognitive Training (TNT) Study
People with HIV (PWH) often suffer from cognitive impairments known as HIV-Associated Neurocognitive Disorder (HAND). Cognitive impairments in PWH are not fully captured by traditional neurocognitive assessment; thus, we must…
- Conditions
- HIV, Aging, Cognitive Function Abnormal, Cognitive Training
- Trial name
- TNT (NCT05773430)
- Testing
- Targeted Neurocognitive Training
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Alzheimer Disease, Healthy Volunteers
Study of TAK-071 in Healthy Participants and Participants With Mild Cognitive Impairment/Mild Alzheimer Disease and Relative Bioavailability (BA) and Food Effect of TAK-071 in Healthy Participants
The purpose of this study was to assess the safety, tolerability, and pharmacokinetic (PK) of TAK-071 when administered as single rising dose (SRD) and multiple rising dose (MRD) orally in healthy participants and participants…
- Trial name
- NCT02769065
- Testing
- TAK-071, Donepezil
- Where
- United States
- Volunteers
- 179 people, healthy volunteers welcome
- Sponsor
- Takeda
Diabetes Mellitus, Cognitive Impairment
Relationship Between Diabetes and Cognitive Impairment Based on Olfactory Function Assessment and Functional MRI
The purpose of this study is to explore the relationship between diabetes and cognitive impairment by olfactory function assessment and functional MRI.
- Conditions
- Diabetes Mellitus, Cognitive Impairment, Obesity
- Trial name
- NCT02738671
- Testing
- Cognitive assessment, functional magnetic resonance imaging, olfactory function measurement
- Where
- China
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Mild Cognitive Impairment, Subthreshold Depression
A One-year Trajectory of Depression Status Changes in Older Adults With MCI and SD: a Longitudinal Cohort Study
The purpose of this study is to investigate the one-year trajectory of changes in depression status in older adults with mild cognitive impairment and subthreshold depression, and to explore relevant risk factors for predicting…
- Conditions
- Mild Cognitive Impairment, Subthreshold Depression, Older Adults
- Trial name
- NCT06308627
- Where
- China
- Volunteers
- 466 people, healthy volunteers welcome
- Sponsor
- Fujian Medical University
Major Depressive Disorder, General Anxiety Disorder
Emotional Brain Networks & Cognitive Functioning in Depression and Anxiety
This study aims to 1) examine common and specific emotional and cognitive dysfunctions between Major Depression and generalized anxiety disorder; 2) Examine emotional and cognitive dysfunctions between the two disorders and…
- Trial name
- NCT03084042
- Testing
- fMRI
- Where
- China
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
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