Clinical trials: Cognitive Disorders
Tinnitus
Cognitive Training for Firefighters With Tinnitus
The purpose of this research study is to determine whether the Brain Fitness Program-Tinnitus affects how tinnitus is perceived and if its use aids in the recovery of cognitive functions that may be affected by tinnitus.
- Trial name
- FEMAICT (NCT01458821)
- Testing
- Brain Fitness Program - Tinnitus
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Huntington Disease
Multi-Modal Digital Monitoring of Disease Symptoms Huntington's Disease
The objective of the study is to validate the use of wearable sensors and digital health technologies for monitoring disease activity in Huntington's Disease (HD).
- Trial name
- BioDigit HD-02 (NCT07315984)
- Where
- 2 sites in United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- BioSensics
Cognitive Dysfunction
Effects Of An 8-Weeks Mindfulness-based Intervention In Individuals With Subjective Cognitive Decline
The European Commission Horizon 2020 programme has funded the SCD-WELL trial to investigate the efficacy of mindfulness-based training to reduce anxiety in individuals with Subjective Cognitive Decline (SCD), in comparison to an…
- Trial name
- SCD-WELL (NCT03005652)
- Testing
- Mindfulness weekly courses for 8 weeks, Health education weekly courses for 8 weeks
- Where
- 4 sites in France, Germany and 2 more
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Dementia, Hearing Loss
Hearing Impairment as a Risk Factor for Dementia in Older Adults
This Doctor of Philosophy (PhD) project is part of a larger project on potentially modifiable risk factors for dementia in a life course perspective, with an overarching aim to improve prevention of dementia and thereby…
- Trial name
- NCT04284384
- Where
- Norway
- Volunteers
- 6,952 people, healthy volunteers welcome
- Sponsor
- Norwegian Centre for Ageing and Health
Mild Cognitive Impairment
Improvement of Memory in Mild Cognitive Impairment
The Clinical Trial will systematically examine the feasibility of remote, caregiver-led tACS for older adults with memory deficits and evaluate whether repeated tACS leads to sustained improvement of neuronal activity and memory…
- Trial name
- NCT05708001
- Testing
- transcranial alternating current stimulation (tACS), high-density electroencephalography (hdEEG), Montreal Cognitive Assessment (MoCA)
- Where
- Switzerland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Lucie Bréchet
Mild Cognitive Impairment, Mild to Moderate Cognitive Impairment
Novel Retinal Imaging Biomarkers in Early Alzheimer's Disease
The goal of this study is to create new retinal imaging processing software useful for the development of novel retinal biomarkers of cognitive impairment associated with Alzheimer's disease (AD).
- Trial name
- NCT01937221
- Testing
- spectral-domain optical coherence tomography (SD-OCT)
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Duke University
Mild Cognitive Impairment
Effectiveness of Tongue Resistance Exercises on Tongue and Swallowing Function in Frail Older Adults With MCI
The purpose of this study is to explore the effects of tongue resistance exercises on tongue muscle strength and swallowing function in frail older adults with mild cognitive impairment living in the community.
- Trial name
- NCT06766487
- Testing
- Tongue resistance exercises, cheek bulging exercises
- Where
- Taiwan
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Chang Gung Medical Foundation
Risk Behavior, Cognitive Decline
Efficacy of a Multidomain Intervention on Lifestyle Risk Factors for Dementia Prevention
Alzheimer's Disease (AD) and other Dementias have far-reaching consequences on the lives of sufferers and their loved ones, not to mention the impact on the healthcare system.
- Trial name
- NCT06748625
- Testing
- Luci Coach-Assisted Intervention
- Where
- Canada
- Volunteers
- 370 people, healthy volunteers welcome
- Sponsor
- LuciLab
Depressive Disorder, Major, Cognitive Dysfunction
bWell-D Pilot Randomized Controlled Trial
The goal of this clinical trial is to determine the acceptability, feasibility, and validity of the bWell Cognitive Care Platform for Depression (bWell-D), a novel Virtual Reality (VR) cognitive assessment and remediation tool…
- Trial name
- NCT06546917
- Testing
- bWell Cognitive Remediation, VR Experience
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Auditory Perceptual Disorders, Aging Problems
Neuroplasticity in Auditory Aging_Project 2 Aims 1 and 2
Millions of elderly adults in the USA have age related hearing loss (ARHL), a malady that affects half of adults 60-69 years, and the majority of older adults.
- Trial name
- NCT03475043
- Testing
- Auditory training: temporal cues
- Where
- United States
- Volunteers
- 405 people, healthy volunteers welcome
- Sponsor
- University of Maryland, College Park
End Stage Renal Disease and Cognitive Impairment
Blood-Brain Barrier Evaluation In Nephrology (BREIN)
Patients with Chronic Kidney Disease (CKD) have impaired psycho-cognitive functions in parallel with deteriorating kidney function.
- Trial name
- BREIN (NCT04328415)
- Testing
- Cerebral scintigraphy
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Assistance Publique Hopitaux De Marseille
Cognitive Impairment
Effect of Technology on Cognitive Function in Elderly
Cognitive technology therapies, including interactive video gaming, computer soft wares and mobile technology, have been used to implement cognitive training and rehabilitation programs.
- Trial name
- cogntion (NCT06378606)
- Testing
- cognitive therapy
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Nourhan Hesham Ali
Atopic Dermatitis
The Effect of Intervention and Mechanism of ICBT on Chronic Itching in Patients With Atopic Dermatitis
Objectives: The study subjects were 180 healthy people from the dermatology clinic of Xiangya Hospital of Central South University and the surroundingcommunity, including 120 AD patients (60 in the ICBT treatment group and 60 in…
- Trial name
- NCT05502848
- Testing
- Internet Cognitive Behavior Therapy
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Xiangya Hospital of Central South University
Mild Cognitive Impairment
Measuring the Impact of a Socially Assistive Robot
Due to increasing age and an increasing prevalence rate of neurocognitive disorders such as Mild Cognitive Impairment and dementia, independent living may become challenging.
- Trial name
- NCT04848155
- Testing
- socially assistive robot
- Where
- Belgium
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Ghent
Cognitive Decline, Mild Cognitive Impairment
The Effects of Chicken Extract and a Peptide Supplement for the Prevention of Cognitive Decline in Non-demented Elderly Adults
This trial investigates the effect of a chicken extract supplement and a peptide supplement on cognitive function and potential mechanisms of action of cognitive decline during ageing, among non-demented elderly adults using a…
- Conditions
- Cognitive Decline, Mild Cognitive Impairment, Aging
- Trial name
- NCT04555655
- Testing
- Chicken extract supplement, Peptide Supplement
- Where
- 3 sites in Taiwan
- Volunteers
- 276 people, healthy volunteers welcome
- Sponsor
- Brand's Suntory Asia
Alzheimer's Disease
Phase II Study for Amyloid Binding Imaging Study of [18F]AV-45 in Patients With Mild Cognitive Impairment, Alzheimer's Disease and Healthy Volunteers
This study will recruit a total of 150 evaluable subjects (30 cognitively normal volunteers, and 60 MCI(Mild cognitive impairment), and 60 AD(Alzheimer's disease), respectively) Each evaluable subject involved in this study must…
- Trial name
- [18F]AV-45 (NCT01238458)
- Testing
- [18F]AV-45 PET amyloid binding imaging
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Inflammation, Immune System
Design and Development of a Functional Plant-based Beverage to Improve Nutritional Status and Immunity for the Early Elderly People to Get Well-healthy Ageing
In 2018, for the first time, the number of people aged 65 and over exceeded the number of children under the age of 5. A rise in ageing societies is coming, and new efforts are needed to ensure that this increase in life…
- Trial name
- Immugold (NCT07409480)
- Testing
- Functional plant-based beverage, Control Beverage
- Where
- Spain
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University Rovira i Virgili
Physical Inactivity, Obesity & Overweight
Development of Human Motor Skills and the Promotion of Motivation for Physical Activity
This study is conducted within the University Centre of Excellence for Studies of Human Motoric at the Faculty of Physical Education and Sport, Charles University.
- Conditions
- Physical Inactivity, Obesity & Overweight, Motor Development, Cognitive Development
- Trial name
- NCT07485270
- Testing
- E-MOVE - Emotional Movement Program for Physical Education
- Where
- 9 sites in Czechia
- Volunteers
- 325 people, healthy volunteers welcome
- Sponsor
- Charles University, Czech Republic
Alzheimer Disease
Discovery and Validation of Genetic Variants Affecting Microglial Activation in Alzheimer's Disease
The primary objectives are to validate that a previously identified gene variant influences the proportion of activated microglia (PAM) and the amount of TSPO binding on PET imaging, to identify novel loci that influence PAM and…
- Trial name
- NCT04840979
- Testing
- 11C-ER176, 18F-florbetaben
- Where
- United States
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- Columbia University
Ketosis, Hypoxia
Intermittent Exogenous Ketosis (IEK) at High Altitude
Altitude-related hypoxia decreases human functional capacity, especially during exercise. Even with prolonged acclimatization, the physiological adaptations are insufficient to preserve exercise capacity, especially at higher…
- Trial name
- NCT06097754
- Testing
- Ketone ester
- Where
- 2 sites in Belgium, Slovenia
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Jozef Stefan Institute
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