Clinical trials: Cognitive Fatigue
Cognitive Deficit in Attention, Musculoskeletal Strain
Effect of Surgeon Warm-up and Mental Visualisation During Robot-assisted Laparoscopic Surgery
Study Design - A Counterbalanced Study Aims - To determine the effect of a) warm-up exercises and b) mental visualisation on the musculoskeletal demands and cognitive demands respectively during robot-assisted laparoscopic…
- Conditions
- Cognitive Deficit in Attention, Musculoskeletal Strain, Fatigue, Surgery
- Trial name
- MURALS2 (NCT05884385)
- Testing
- Simulated exercises, Mental Visualisation
- Where
- United Kingdom
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Lancaster University
Insomnia, COPD
A Behavioral Therapy for Insomnia Co-existing With COPD
Difficulty falling asleep, staying asleep or poor quality sleep (insomnia) is common in people with chronic obstructive pulmonary disease.
- Conditions
- Insomnia, COPD, Chronic Obstructive Pulmonary Disease, Fatigue
- Trial name
- NCT01973647
- Testing
- Cognitive Behavioral Therapy for Insomnia, COPD Education, Attention Control
- Where
- United States
- Volunteers
- 109 people
- Sponsor
- University of Illinois at Chicago
Inflammatory Bowel Diseases
Mindfulness-based Cognitive Therapy for Patients With Inflammatory Bowel Disease
Considering the limited availability of psychosocial interventions for IBD, this study aims to investigate MBCT as an adjunctive treatment to treatment as usual to reduce psychological stress and improve sleep quality/regularity…
- Trial name
- NCT04646785
- Testing
- Mindfulness-based cognitive therapy + TAU, Treatment as usual (TAU)
- Where
- 4 sites in Netherlands
- Volunteers
- 142 people
- Sponsor
- Radboud University Medical Center
Severe Chronic Obstructive Pulmonary Disease, Dyspnea
The Effectiveness Pulmonary Telerehabilitation and Cognitive Telerehabilitation in COPD Patients
The aim of our study is to compare the effectiveness of the supervized pulmonary telerehabilitation program and the cognitive telerehabilitation method, which includes pulmonary telerehabilitation methods, in patients with severe…
- Conditions
- Severe Chronic Obstructive Pulmonary Disease, Dyspnea, Muscle Weakness, Fatigue
- Trial name
- NCT05222295
- Testing
- Supervised Pulmonary Telerehabilitation, Cognitive Telerehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Saglik Bilimleri Universitesi
Multiple Sclerosis, Insomnia
A Digital Therapeutic to Improve Insomnia in Multiple Sclerosis: A Randomized Controlled Trial.
The goal of this randomized controlled trial is to test the effectiveness of digital cognitive behavioral therapy for insomnia (dCBT-I) compared with digital patient education about insomnia for people with Multiple Sclerosis…
- Trial name
- NorseMS (NCT06113666)
- Testing
- Digital Cognitive Behavioral Therapy for Insomnia (dCBT-I), Digital patient education about insomnia (PE)
- Where
- Norway
- Volunteers
- 550 people
- Sponsor
- St. Olavs Hospital
Chronic Fatigue Syndrome
A Rehabilitation Program for Adolescents With Chronic Fatigue Syndrome
The aim of the programme is to develop a treatment model for adolescents with Chronic Fatigue Syndrome. The program consists of 4 elements lasting for 12 months, psychoeducation reflecting the current knowledge about the disease…
- Trial name
- NCT01806246
- Testing
- integrative rehabilitation program
- Where
- Norway
- Volunteers
- 13 people
- Sponsor
- St. Olavs Hospital
MELAS Syndrome, Lebers Hereditory Optic Neuropathy With Extra Ocular Symptoms (LHON-Plus)
A Basket Clinical Study to Assess Glycerol Tributyrate in Patients With Mitochondrial Encephalopathy, Lactic Acidosis, Stroke-like Episodes (MELAS) or Leber's Hereditary Optic Neuropathy-Plus (LHON-Plus)
This is a parallel arm non-randomized dose-escalation, open-label basket exploratory phase 1 clinical trial where Mitochondrial encephalopathy, lactic acidosis, stroke-like episodes (MELAS) and Leber's hereditary optic…
- Trial name
- NCT06792500
- Testing
- Glycerol Tributyrate
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- George Washington University
Brain Fog
Transcranial Direct Current Stimulation (tDCS)
Cognitive impairment refers to when an individual struggles to learn, concentrate, remember, or make decisions. This can be due to underlying neurological diseases (i.e.
- Trial name
- tDCS (NCT05524233)
- Testing
- Active Transcranial Direct Stimulation
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Baylor College of Medicine
Iron-deficiency, Iron Deficiency Anemia
Fatigue, Quality of Life, Cognitive Function and Physical Ability in Patients Suspected of Colorectal Malignancy
The aim is to investigate if iron deficiency at the time of colorectal cancer diagnosis has an influence on fatigue, quality of life, cognition and physical ability.
- Conditions
- Iron-deficiency, Iron Deficiency Anemia, Colorectal Cancer, Fatigue
- Trial name
- NCT04749589
- Testing
- iron deficiency
- Where
- 3 sites in Denmark
- Volunteers
- 200 people
- Sponsor
- Esbjerg Hospital - University Hospital of Southern Denmark
Heat Intolerance, Heat Stress
Acquiring and Targeting Heat Exposures Necessary for Action
The purpose of this research study is to better understand ways that women and men differ physiologically, cognitively, physically, and cellularly to better prescribe helpful interventions that will prevent injury and risk of…
- Conditions
- Heat Intolerance, Heat Stress, Fatigue; Heat
- Trial name
- ATHENA (NCT05678738)
- Testing
- Antioxidant Berry Supplementation, Acute and Chronic Exercise-Heat Stress
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
COPD, Upper Extremity
Cognitive Impairment and Upper Extremity Performance in COPD
Within the scope of this study, COPD patients will be divided into two groups according to cognitive dysfunction. Pulmonary function test, COPD assessment scale, Mini-Mental State Examination and Montreal Cognitive Assessment…
- Conditions
- COPD, Upper Extremity, Upper Limb Function, Cognitive Impairment
- Trial name
- COPD (NCT05137483)
- Testing
- Functional tests
- Volunteers
- 80 people
- Sponsor
- Izmir Katip Celebi University
Gulf War Illness, Chronic Fatigue
Coenzyme Q10 Phase III Trial in Gulf War Illness
The primary objective of this clinical trial is to determine if treatment with ubiquinol, a form of coenzyme Q10, improves the physical function of men and women Veterans suffering from Gulf War Illness (GWI).
- Conditions
- Gulf War Illness, Chronic Fatigue, Ubiquinol, Coenzyme Q10
- Trial name
- NCT02865460
- Testing
- Ubiquinol
- Where
- 4 sites in United States
- Volunteers
- 100 people
- Sponsor
- VA Office of Research and Development
Breast Cancer, Cognitive Dysfunction
Reducing Breast Cancer-related Fatigue and Improving Cognition With Non-Invasive Brain Stimulation
This study will test the preliminary efficacy of transcranial direct current stimulation (tDCS) to improve fatigue and cognition in women with a history of breast cancer and persistent fatigue.
- Conditions
- Breast Cancer, Cognitive Dysfunction, Fatigue
- Trial name
- NCT03143894
- Testing
- tDCS
- Where
- 3 sites in United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Healthy
Effects of Supradyn® Energy 3RDA on Fatigue/Stress, Substrate Metabolism During Exercise and Demanding Cognitive Tasks
Investigation of the acute and chronic effects of Supradyn® Energy 3RDA on subjective ratings of 'fatigue/stress', substrate metabolism and blood biomarkers of recovery, as a consequence of exercise and metabolically demanding…
- Trial name
- NCT03003442
- Testing
- Supradyn® Energy 3RDA
- Where
- United Kingdom
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Fibromyalgia
Subjective Ageing in Fibromyalgia
Subjective age or felt age is the term used for how the person feels; one can feel same, younger or older than their actual age.
- Trial name
- NCT03966820
- Where
- Turkey (Türkiye)
- Volunteers
- 262 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Obstructive Sleep Apnea
Brain Fog in Sleep Apnea
Objective: This observational, cross-sectional pilot study aims to assess "Brain Fog" (cognitive symptoms impacting memory, attention, and concentration) in severe Obstructive Sleep Apnea (OSA) patients.
- Trial name
- BF -OSA (NCT06664450)
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Cognitive/Functional Effects, Constipation, Impaction, and Bowel Obstruction
Probiotic Therapy in Preventing Gastrointestinal Complications in Patients Undergoing Chemotherapy and Pelvic Radiation Therapy
RATIONALE: Probiotic therapy may reduce or prevent gastrointestinal complications in patients undergoing chemotherapy and pelvic radiation therapy.
- Conditions
- Cognitive/Functional Effects, Constipation, Impaction, and Bowel Obstruction, Diarrhea, Fatigue
- Trial name
- NCT01473290
- Testing
- live freeze-dried lactic acid bacteria probiotic
- Sponsor
- Alliance for Clinical Trials in Oncology
Psychological Stress, Mental Fatigue
Psychological Impacts of Exercise Snacks Versus Traditional Exercise: A Comparative Study
This study investigates the comparative psychological impacts of a high-frequency "Exercise Snacks" (ESG) protocol versus a traditional continuous exercise (TEG) regimen on healthy young adults.
- Conditions
- Psychological Stress, Mental Fatigue, Cognitive Dysfunction, Emotional Well-being
- Trial name
- ES (NCT07666893)
- Testing
- Exercise Snacks Group (ESG), Traditional Exercise Group (TEG)
- Where
- China
- Volunteers
- 199 people, healthy volunteers welcome
- Sponsor
- Lincoln University College
Long COVID, PASC Post Acute Sequelae of COVID 19
Brain Stimulation in Long COVID
Cognitive problems and severe fatigue are two frequently occurring symptoms in long COVID, also known as Post-Covid Condition or Post-Acute Sequelae of COVID-19 (PASC), and their causes are currently unknown.
- Conditions
- Long COVID, PASC Post Acute Sequelae of COVID 19, Post COVID-19 Condition (PCC)
- Trial name
- MALIBU (NCT07278206)
- Testing
- Repetitive Transcranial Magnetic Stimulation
- Where
- Netherlands
- Volunteers
- 66 people
- Sponsor
- Amsterdam UMC, location VUmc
Parkinson Disease
Transcranial Direct Current Stimulation for Cognitive Improvement in Parkinson's Patients
The investigators hypothesize that multi-session anodal tDCS (atDCS) of the left dorsolateral prefrontal cortex (LDLPFC) will induce long-lasting effects in improving cognitive function and reducing cognitive fatigue and…
- Trial name
- tDCS (NCT03191916)
- Testing
- transcranial direct current stimulation
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Sanford Health