Clinical trials: Cognitive Frailty
Intrinsic Capacity, Frailty
Project ICOPE Brazil: Assessment of Intrinsic Capacity in Brazilian Older Adults
The ICOPE Brazil study aims to understand aging trajectories in Brazil, especially healthy aging trends based on intrinsic capacity, a collective of mental and physical capacities one may have to maintain their functional ability…
- Conditions
- Intrinsic Capacity, Frailty, Aging, Healthy Aging
- Trial name
- ICOPE-BR (NCT06968702)
- Volunteers
- 3,838 people
- Sponsor
- University of Sao Paulo
Sleep Disorders, Frailty
Impact of Sleep Disorders and Digital Support on Older People's Health
The goal of this observational study is to learn about the effects of sleep disorders on health and ageing in older people over the age of 65.
- Conditions
- Sleep Disorders, Frailty, Cognitive Impairment, Quality of Life
- Trial name
- SOMNUS-DARE (NCT06944600)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Parma
Cognitive Frailty
The Effect of Dual Tasks of Digital Technology on Cognitive Function and Physical Activity in the Older Adults With Cognitive Frailty
Background: Cognitive frailty is a state that combines physical weakness and cognitive impairment. As age increases, the prevalence rate also increases.
- Trial name
- NCT06797440
- Testing
- Dual tasks of digital technology
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- National Taipei University of Nursing and Health Sciences
Cognitive Impairment, Old Age; Debility
Dietary Supplementation and Cognitive Functions in the Elderly
In recent years, globally, there has been a growth in both the size and the proportion of older adults in the world population. The World Health Organization (WHO) has estimated that by 2030, 1 in 6 people will be 60 years of age…
- Trial name
- ESPINS (NCT06352099)
- Testing
- Dietary supplement with micronised diosmin, hesperidin and herbal extracts
- Where
- Italy
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Cognitive Decline, Sarcopenia
Holistic Integration for Healthy Longevity and Aging in Place
Background: Taiwan is experiencing rapid population aging, with a growing prevalence of chronic diseases and functional impairments among older adults.
- Conditions
- Cognitive Decline, Sarcopenia, Depression Disorders, Nutrition Disorder
- Trial name
- HIHOPE (NCT06882434)
- Testing
- Local intervention program, Referral Process, Telehealth Education & Digital Integration
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Ageing, Disability
The Beijing Longitudinal Disability Survey in Community Elderly
The goal of this observational study is to establish the prospective cohort of the Beijing Longitudinal Disability Survey in Community Elderly (BLINDSCE) to explore the high-risk factors and preventive interventions for…
- Conditions
- Ageing, Disability, Cognitive Impairment, Frailty
- Trial name
- BLINDSCE (NCT06863727)
- Where
- China
- Volunteers
- 1,962 people, healthy volunteers welcome
- Sponsor
- Xuanwu Hospital, Beijing
Frailty, Cognitive Impairment
A Practical Platform for In-Home Remote Monitoring of Cognitive Frailty
Cognitive frailty, characterized by the coexistence of physical frailty and cognitive impairment, is a robust indicator of cognitive decline.
- Conditions
- Frailty, Cognitive Impairment, Dementia, Cognitive Impairment, Mild
- Trial name
- NCT05754021
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Baylor College of Medicine
Physical Frailty, Mild Cognitive Impairment (MCI)
Effects of Music-with-Movement on Cognitive and Physical Performance of People With Potentially Reversible Cognitive Frailty: a Randomised Controlled Trial
This study aims to evaluate the effects of Music-with-Movement Simultaneous Cognitive-Motor Dual-Task Training (MM-SDTT) on cognitive and physical performance in older adults with cognitive frailty coexisting with mild cognitive…
- Conditions
- Physical Frailty, Mild Cognitive Impairment (MCI), Cognitive Frailty
- Trial name
- NCT06791720
- Testing
- music-based cognitive-motor dual-task training/exercise, Social Gatherings
- Where
- Hong Kong
- Volunteers
- 113 people
- Sponsor
- The Hong Kong Polytechnic University
Frailty, Perioperative/Postoperative Complications
Correlation of Preoperative Global Olfactory Function With Frailty, Perioperative Neurocognitive Disorders and Mortality
The aims of this research project are to evaluate whether global olfactory impairment is a reliable indicator of preoperative frailty and cognitive impairment, and whether it may predict postoperative neurocognitive disorders…
- Conditions
- Frailty, Perioperative/Postoperative Complications, Olfactory Disorder, Neurocognitive Disorders
- Trial name
- NCT04761458
- Testing
- Olfactory function testing, Edmonton Frail Scale, Clinical Frailty Scale
- Where
- Belgium
- Volunteers
- 215 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Frailty, Vision and Hearing Loss
Health Determinants in Older Adults Living At Home
The observational study will conduct interprofessional assessments by registered nurses, physiotherapists, and occupational therapists of health determinants (i.e., frailty, physical, cognitive, and sensory function, mental and…
- Conditions
- Frailty, Vision and Hearing Loss, Cognitive Function, Social 1, Mental Health Issue
- Trial name
- NCT05837728
- Testing
- Health promoting assessment of older adults living at home
- Where
- Norway
- Volunteers
- 40 people
- Sponsor
- University of Stavanger
Aging, Cognitive Decline
Blood Flow Restriction and High-intense Resistance Training in Aging: Interactions Between Neuroplasticity and Muscle
BRAIN-M is a randomized controlled trial designed to examine the effects of a single bout or 12 weeks of blood-flow restriction training or high-intensity resistance training on cognitive function, brain health, muscular…
- Conditions
- Aging, Cognitive Decline, Sarcopenia, Frailty
- Trial name
- BRAIN-M (NCT05744167)
- Testing
- BFRT, MDRT
- Where
- Lithuania
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Lithuanian Sports University
Frailty, Oncology Problem
PATH Program for for Severely Frail or Cognitively Impaired Patients Scheduled for Cancer Surgery.
This is a single center, non-blinded randomized control trial taking place at the Queen Elizabeth II hospital (QEII) in Nova Scotia.
- Conditions
- Frailty, Oncology Problem, Cognitive Impairment
- Trial name
- NCT06022666
- Testing
- Geriatric assessment
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- Nova Scotia Health Authority
Postoperative Delirium, Cognitive Function Abnormal
EEG Characteristics and Postoperative Delirium
The goal of this [type of study: observational study ] is to [compare Energy differences in various bands of intraoperative electroencephalogram in elderly patients with postoperative delirium and non delirium.] in [describe…
- Conditions
- Postoperative Delirium, Cognitive Function Abnormal, PSI, Frailty
- Trial name
- NCT06102967
- Testing
- delirium
- Where
- China
- Volunteers
- 66 people
- Sponsor
- Zhuo Liu
Sleep Disorder, Insomnia
Brain Gym Therapy on Quality of Sleep Among Elderly People
This clinical trial aims to evaluate the impact of Brain Gym Therapy on the quality of sleep among elderly individuals attending healthcare facilities.
- Conditions
- Sleep Disorder, Insomnia, Cognitive Function Abnormal, Old Age; Debility
- Trial name
- BG/E (NCT06553690)
- Testing
- Brain Gym Therapy
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Cairo University
Frailty, Cognitive Decline
The Effectiveness of a Dual-task Training Program
The purpose of this study is to explore the effect of a dual-task training intervention on cognitive function,physical function, depression symptoms and quality of life in middle-aged and elderly people with cognitive impairment.
- Trial name
- NCT06450119
- Testing
- walking training, cognition training
- Volunteers
- 196 people
- Sponsor
- Taipei Medical University
Frail Elderly
Long-term Effects of Interventional Strategies to Prevent Cognitive Decline in Elderly.
The MAPT PLUS study is a two-year extension of follow-up of the patients included in the MAPT preventive study, after completion of the interventions. Subjects in the four groups of the MAPT study will be prospectively followed.
- Trial name
- MAPT-PLUS (NCT01513252)
- Testing
- Gröber and Buschke test
- Where
- 13 sites in France, Monaco
- Volunteers
- 1,028 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Cognitive Change, Physical Performance
Coginitve and Physical Functions in Geriatric İndividuals
The aim of this study is to investigate the relationship between cognitive functions with physical performance, grip strength, walking speed, mobility, and frailty in geriatric individuals.
- Conditions
- Cognitive Change, Physical Performance, Frailty, Mobility
- Trial name
- NCT06400134
- Testing
- Cognitive Function, Physical Performance, Grip Strength
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
Delirium, Cognitive Decline
Dexmedetomidine or Clonidine Infusion for Prevention of Delirium After Open Heart Surgery
A parallel-group treatment, five-centre, participant and investigator masked, three-arm study to assess the safety and effectiveness of dexmedetomidine or clonidine infusion compared to placebo for the prevention of delirium and…
- Conditions
- Delirium, Cognitive Decline, Frailty
- Trial name
- ALPHA2PREVENT (NCT05029050)
- Testing
- Dexmedetomidine, Clonidine, Natriumchlorid
- Where
- 5 sites in Norway
- Volunteers
- 900 people
- Sponsor
- Oslo University Hospital
Cardiovascular Diseases, Diabetes Mellitus
The Kunshan Elderly Health Study
The Kunshan Elderly Health Study (KEHS) is a community-based prospective cohort study of chronic disease, mortality and associated factors among elderly adults in Kunshan, Eastern China.
- Conditions
- Cardiovascular Diseases, Diabetes Mellitus, Cancer, Cognitive Impairment
- Trial name
- KEHS (NCT05141565)
- Testing
- No intervention
- Where
- China
- Volunteers
- 5,945 people
- Sponsor
- Soochow University
Frailty, Motoric Cognitive Risk Syndrome
Cognitive Prefrail and Frailty, and Motoric Cognitive Risk Syndrome: Prevalence and Association With Incident Adverse Health Events
We defined a new and early condition in the spectrum of cognitive frailty: the "cognitive-prefrailty" which is a combination of prefrailty stage and subjective cognitive impairment (SCI).
- Conditions
- Frailty, Motoric Cognitive Risk Syndrome, Cognitive-prefrailty
- Trial name
- NCT04275817
- Testing
- Data collection
- Where
- Canada
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- Jewish General Hospital