Clinical trials: Cognitive Function Assessment
Cognitive Function, Mood
Investigation of the Acute and Chronic Cognitive and Mood Effects of CP9700 in Humans
This acute-on-chronic study will examine the effectiveness of CP9700 for improving cognitive performance and mood in healthy young adults.
- Trial name
- NCT03526406
- Testing
- CP9700
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Reading
Mild Cognitive Impairment (MCI)
Nutritional Intervention With the Dietary Supplement, Immunocal® in MCI Patients: Promotion of Brain Health
Alzheimer disease (AD) is a dementing illness characterized by progressive neuronal degeneration, gliosis, and the accumulation of intracellular inclusions and extracellular deposits of amyloid in discrete regions of the basal…
- Trial name
- NCT03448055
- Testing
- Immunocal
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- Immunotec Inc.
Multiple Sclerosis, Cognitive Change
Remote Evaluation of MIND Diet
The goal of this clinical trial is to learn if increasing adherence to a Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet pattern improves thinking ability and memory compared to a healthy control diet in…
- Conditions
- Multiple Sclerosis, Cognitive Change, Nutrition, Healthy
- Trial name
- REMIND (NCT06450977)
- Testing
- MIND Diet, Control Diet
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Illinois at Urbana-Champaign
Cognition
D2D Normative Data for Remote Assessments
Phase 1: This is a remote observational study in which participants will complete cognitive assessments developed by Posit Science.
- Trial name
- NCT03206775
- Testing
- Cognitive Assessments (Phase 1), Cognitive Battery A (Phase 2), Cognitive Battery B (Phase 2)
- Where
- 2 sites in United States
- Volunteers
- 1,271 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Mild Cognitive Impairment
Water-based Activity to Enhance Recall in Veterans: A Randomized Clinical Trial
This four-year study will evaluate the efficacy of an exercise training augmentation for cognitive training intervention to improve memory performance in Veterans with a diagnosis of amnestic Mild Cognitive Impairment (aMCI).
- Trial name
- WATER-VET (NCT04296565)
- Testing
- Usual Care, WATER+CT
- Where
- United States
- Volunteers
- 121 people
- Sponsor
- VA Office of Research and Development
Postoperative Cognitive Dysfunction
Optic Nerve Sheath Diameter and Cognitive Outcomes in Bentall Surgery
Bentall surgery is a major cardiac procedure involving replacement of the ascending aorta, aortic root, and aortic valve, typically requiring cardiopulmonary bypass (CPB) and sometimes deep hypothermic circulatory arrest (DHCA).
- Trial name
- ONCOB (NCT07452367)
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Dementia, Mild Cognitive Impairment
SAMi Intervention Study to Evaluate Smartwatch Interventions in Persons With MCI and Dementia
Assistive Technologies (ATs) can help people living with dementia (PwD) maintain their everyday activity. Still, there is a gap between potential and supply. Involving future users can close the gap.
- Conditions
- Dementia, Mild Cognitive Impairment, Alzheimer Disease, Dementia With Lewy Bodies
- Trial name
- SAIN_UMR (NCT05885620)
- Testing
- drinking reminder and cognitive task (smartwatch-based application)
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- University of Rostock
LTC-to-hospital Transfer Decision-making
Evaluation of the STEP Intervention for Long-Term Care Residents Facing Hospital Transfer Decisions
This trial will evaluate whether the Supporting Transitions and Empowering Preferences (STEP) toolkit can improve decision-making about hospital transfers in long-term care residents and their substitute decision-makers and…
- Trial name
- STEP (NCT07153341)
- Testing
- STEP Decision Support Toolkit
- Where
- 2 sites in Canada
- Volunteers
- 200 people
- Sponsor
- Bruyère Health Research Institute.
End Stage Renal Disease
Dehydr8 and Deactiv8
Managing fluid status is a complex but fundamental part of the clinical care of people receiving haemodialysis (HD). Day-to-day fluid management is usually based on the concept of 'target weight' - the weight used to determine…
- Trial name
- NCT03179072
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- University of Portsmouth
Pulmonary Arterial Hypertension
Cognitive Alterations in Pulmonary Arterial Hypertension (PAH)
Pulmonary Arterial Hypertension (PAH) is a rare chronic disease marked by a pathological and sustained increase in pulmonary artery pressure as a result of structural and functional changes within the pulmonary vasculature.
- Trial name
- COG-PAH (NCT07391228)
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Alessandra Gorini
Cognitive Impairment, Covid19
The MentalPlus® for Assessment and Rehabilitation of Cognitive Function After Remission of the Symptoms of COVID-19
This study evaluates and rehabilitates the cognitive functions of attention, memory, visual perception, language, and executive by the mentalPlus® digital game of COVID-19 surviving patients after remission of symptoms.
- Conditions
- Cognitive Impairment, Covid19, Cognitive Dysfunction, Depression, Anxiety
- Trial name
- MP-COVID (NCT04632719)
- Testing
- The use of the MentalPlus® digital game for assessment and rehabilitation of cognitive function after remission of the symptoms of COVID-19
- Where
- 2 sites in Brazil
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Huntington's Disease
A First-in-human Study of the Effects of SRP-1005 in Participants With Huntington's Disease
This is a first-in-human, multi-center trial studying the effects of SRP-1005 in participants with Huntington's disease (HD).
- Trial name
- NCT07536061
- Testing
- SRP-1005
- Where
- 5 sites in Australia, New Zealand and 2 more
- Volunteers
- 32 people
- Sponsor
- Sarepta Therapeutics, Inc.
Older Adults Without Any Specific Clinical Condition
Impact of a Technology Mediated Dance Intervention
This study aims to investigate whether a technology-mediated dance impacts on psychosocial, physical and cognitive functions of the old adults when compared to usual activities.
- Trial name
- NCT05460039
- Testing
- Dance mediated by tecnhology
- Where
- Portugal
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Aveiro University
Stroke
Effects of Strategy Training for Physical Activity (STPA) on the Post-stroke Executive Dysfunction
The goal of this randomized controlled trial is to examine if combining strategy training and physical activity (STPA) works to improve executive function in community-dwelling adults with post-stroke cognitive impairment.
- Trial name
- STPA (NCT06790173)
- Testing
- Strategy training for physical activity, Physical activity, Education
- Where
- 5 sites in Taiwan
- Volunteers
- 120 people
- Sponsor
- Taipei Medical University
Acute Leukemia
Evaluation of Functional and Nutritional Parameters in Fit Acute Leukemia Patients
This single-center observational prospective longitudinal study will assess cognitive, physical, and nutritional performance in acute leukemia patients undergoing intensive chemotherapy.
- Trial name
- FisNutEma (NCT06937554)
- Testing
- observational follow up aimed at evaluating functional, physical, cognitive, and nutritional parameters
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- University of Rome Tor Vergata
Cognitive Impairment, Cognitive Decline
Normative Values for the German Version of the Montreal Cognitive Assessment (MoCA)
This observational cohort study in healthy volunteers establishes normative data for the German version of the Montreal Cognitive Assessment (MoCA) and investigates the possible impacts of demographics on the MoCA total score.
- Conditions
- Cognitive Impairment, Cognitive Decline, Cognition Disorders, Cognitive Symptom
- Trial name
- MoCA-Norm (NCT03246269)
- Testing
- MoCA
- Volunteers
- 334 people, healthy volunteers welcome
- Sponsor
- Andreas Monsch
Executive Functions, Memory Functions
Multi-domain Versus Uni-Domain Training on Executive Control and Memory Functions of Older Adults
Age-related cognitive decline affects negatively daily living and quality of life of older adults. Previous research has shown a moderate impact of cognitive and physical training on the cognitive functioning of elders.
- Trial name
- VIBAL (NCT03823183)
- Testing
- Cognitive training, Physical training, Cognitive control
- Where
- Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional de Educación a Distancia
Healthy Older Adults
Effect of Dual Task in Aquatic Physical Therapy in Older Adults
Population ageing is associated with declines in motor and cognitive functions, which compromise autonomy and increase the risk of falls and cognitive impairment.
- Trial name
- NCT07270094
- Testing
- Aquatic Dual-Task Training, Conventional Aquatic Exercise
- Where
- Portugal
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Instituto Politécnico de Leiria
Breast Cancer
CHEmotherapy and Cognitive Deterioration in Patients With Operable Breast Cancer: Impact of Cognitive Rehabilitation (CHEMOFOG)
An interventional, non-pharmacological, monocentric study evaluating the effectiveness of cognitive rehabilitation in counteracting chemotherapy-induced cognitive impairment (CRCI) in women with operable breast cancer treated…
- Trial name
- CHEMOFOG (NCT06435559)
- Testing
- Neurotablet® and Neuropsychological evaluations, Neuropsychological evaluations
- Volunteers
- 128 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Vitamin D Deficiency, Metabolic Syndrome
Vitamin D Supplementation and Metabolism in Vitamin D Deficient Elderly
The purpose of this study is to examine the effects of Vitamin D supplementation on the reasons (mechanisms) underlying the development of type 2 diabetes, metabolic syndrome (high blood pressure, cholesterol, diabetes, body…
- Trial name
- VitD (NCT01145703)
- Testing
- RDA Vitamin D3 only, Vitamin D2/3 Repletion only, Vitamin D2/3 Repletion + AEX
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Baltimore VA Medical Center