Clinical trials: Cognitive Function and Mental Health
Mild Cognitive Impairment, Chronic Inflammation
The Grounded Brain: How Sleeping Grounded Affects Memory and Perceptions
Grounding (Earthing) refers to the practice of contacting the Earth or a properly installed grounding mat with the body. Previous studies on grounding have shown positive effects body-wide inflammation, acute and chronic pain…
- Trial name
- NCT05050812
- Testing
- grounding mat
- Volunteers
- 8 people
- Sponsor
- California Institute of Integral Studies
Cognition, Affect (Mental Function)
PRECOG Pilot Project
This pilot study aims to investigate the chronic effects of a prebiotic blend on cognitive, affective and gut microbiome outcomes in healthy adults aged 60-75 years.
- Conditions
- Cognition, Affect (Mental Function), Gut Microbiome
- Trial name
- NCT06911957
- Testing
- Prebiotic blend
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Reading
Aging, Cognitive Impairment
Leveraging Social Networks to Improve Sleep and Mindfulness Among Older Adults in Residential Housing Facilities
The aim of this study is to design a sleep and mindfulness intervention to improve sleep, quality of life, and cognitive function among older adults.
- Conditions
- Aging, Cognitive Impairment, Sleep
- Trial name
- NCT06989619
- Testing
- Sleep health and mindfulness intervention
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Cognitive Deterioration
Effects of Petroleum Compounds on Psychological Health and Cognitive Functions
Over the last decade, awareness of the effects of hydrocarbon fuels on neurodegenerative disorders has increased significantly, as they are ubiquitous environmentally toxic chemicals that affect the central nervous system and…
- Trial name
- NCT06380998
- Testing
- whey protien
- Where
- Egypt
- Volunteers
- 196 people
- Sponsor
- Assiut University
Dementia, Alzheimer's Disease and Related Dementias
HomeCare Medication Management for People With Dementia
This study will evaluate whether the HomeCare medication management system can improve medication adherence and related outcomes for adults age 65 and older living with dementia, Alzheimer's disease, or related dementias.
- Trial name
- NCT07872072
- Testing
- HomeCare
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- HiDO Technologies
Cognitive Impairment, Frail Elderly Syndrome
Cognition and the Immunology of Postoperative Outcomes
This research will test the hypothesis that immune system disequilibrium / dysfunction explains why preoperative cognitive impairment is a strong predictor of postoperative morbidity in older surgical patients.
- Conditions
- Cognitive Impairment, Frail Elderly Syndrome, Delirium, Surgery
- Trial name
- NCT04792983
- Testing
- No intervention
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- Brigham and Women's Hospital
Insomnia
Online COgnitive Behavioural Therapy for Sleep and Mental Health for Older Adults With Insomnia and Subjective Cognitive Complaints
The goal of this randomized controlled clinical trial is to assess a novel cognitive-behavioral program for sleep and mental health using a multidomain web platform (eCBTi+) in participants with insomnia and subjective cognitive…
- Trial name
- e-COSMOS (NCT06032377)
- Testing
- cognitive behavioral therapy for sleep, anxiety, and depression, education about healthy nutrition habits and communication in older age
- Where
- 2 sites in Canada
- Volunteers
- 275 people, healthy volunteers welcome
- Sponsor
- Centre de Recherche de l'Institut Universitaire de Geriatrie de Montreal
Respiratory Disease
REspiratory reHABilitation and PSYchiatric Comorbidities
Patients with respiratory insufficiency, chronic obstructive pulmonary disease (COPD), pulmonary fibrosis, asthma, bronchiectasis, and, to a lesser extent, other pathologies that result in respiratory insufficiency and require…
- Trial name
- REHABPSY (NCT06229600)
- Testing
- Standard rehabilitation
- Where
- 6 sites in Italy
- Volunteers
- 994 people
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
Physician Well-being, Cognitive Function
Performance Nutrition for Residents and Fellows
Currently, residents commonly experience dehydration and poor nutrition during nighttime duty hours as a result of heavy work load, lack of time to take nutrition and hydration breaks, or limited or no access to healthy food and…
- Conditions
- Physician Well-being, Cognitive Function, Diet Modification, Diet Habit
- Trial name
- NCT03698123
- Testing
- Dietary Modification
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Stanford University
Mild Cognitive Impairment (MCI), Dementia
Integration of VR and AR Dementia Prevention Health Education Progrom for Older Adults With Mild Cognitive Impairment
The goal of this randomized controlled trial is to evaluate the effectiveness of Virtual Reality (VR)-based cognitive health education for older adults with mild cognitive impairment (MCI) in Taiwan.
- Conditions
- Mild Cognitive Impairment (MCI), Dementia, Health Literacy, Self-Efficacy
- Trial name
- NCT06888986
- Testing
- VR Dementia Prevention Health Education Module
- Where
- Taiwan
- Volunteers
- 139 people
- Sponsor
- National Taiwan Normal University
Forest Therapy for Cognition
Effects of Forest Therapy on Cognitive Performance and Mental Health in Older Adults Health in Older Adults
In Taiwan, aging is happening at a fast pace. The Taiwan Ministry of Interior officially announced that Taiwan will become an aged society in April 2018 and is expected to transition into a hyper-aged society within eight years.
- Trial name
- NCT05359289
- Testing
- Forest therapy training, Senior fitness training, Board Games
- Where
- 2 sites in Taiwan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Tobacco Use Disorder, Nicotine Dependence, Cigarettes
Effects of Nicotine Dependence on Multidimensional Health Outcomes
Nicotine, a major toxic component of cigarette smoke, together with carbon monoxide (CO), constitutes a significant environmental exposure with systemic effects.
- Trial name
- NCT07474623
- Testing
- Comprehensive Clinical Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 212 people, healthy volunteers welcome
- Sponsor
- Izmir Democracy University
Mental Health Wellness 1, Work Related Stress
Mental Balance Study
The proposed design is a randomised, double-blind, controlled, crossover intervention assessing the effects of an active intervention, containing Scutellaria baicalensis and Crataegus, versus placebo, on stress, cognition, sleep…
- Trial name
- NCT05757050
- Testing
- Re-Focus "Verum" Tablets
- Where
- United Kingdom
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- A. Vogel AG
Cognitive Function, Memory
A Clinical Trial to Investigate the Efficacy of the Brain Blossom Supplement to Improve Cognitive Function and Memory
This study evaluates the efficacy of BioNatureHealth's Brain Blossom supplement in improving cognitive function and memory in adults aged 50-70 years.
- Conditions
- Cognitive Function, Memory, Cognitive Decline
- Trial name
- NCT07564804
- Testing
- Dietary Supplement: Brain Blossom
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Bio Nature Health
Preterm Birth, Psychological Distress
Expected and Actual Preterm-Birth and Parental Distress: Impact on Children's Mental Health
The purpose of the present study is the assessment of the mental health and cognitive development of children 6-11 years after premature or term birth.
- Conditions
- Preterm Birth, Psychological Distress, Mental Health, Cognitive Functioning
- Trial name
- NCT06627140
- Testing
- Diagnostic procedures
- Where
- Germany
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Goethe University
Mild Cognitive Impairment, Hypertension
Computerized Cognitive Training to Protect Cognitive Function Among Hypertension Patients
Hypertension is an risk factor for cognitive impairment. The primary objective of this study is to evaluate the efficacy of 12-week computerized cognitive training in people with hypertension and mild cognitive impairment.
- Trial name
- NCT05704270
- Testing
- Multi-domain adaptive cognitive training, Basic cognitive training with no difficulty change
- Where
- 2 sites in China
- Volunteers
- 200 people
- Sponsor
- Beijing Anzhen Hospital
Alzheimer Disease, Aging
Lifestyle for the BRAin Health - Time Restricted Eating and Mindfulness
The study aims to evaluate the effects of a 9-month intervention combining yoga-based mindfulness techniques, cognitive training, and nutritional counseling on cognitive function, plasma markers of neurodegeneration (tau…
- Conditions
- Alzheimer Disease, Aging, Lifestyle Factors, Cognitive Impairment
- Trial name
- LIBRA REMIND (NCT07042087)
- Testing
- Mindfulness Yoga, Time-Restricted Eating with nutritional counseling promoting a flexitarian dietary pattern, Cognitive Training
- Where
- Czechia
- Volunteers
- 48 people
- Sponsor
- St. Anne's University Hospital Brno, Czech Republic
Post Traumatic Stress Disorder PTSD, Quality of Life
Effectiveness of Trauma Treatment in the Specialist Health Care Services
Post-traumatic stress disorder (PTSD) is a common mental illness. Treatments for PTSD are regarded as highly effective, but a large-scale, prospective, longitudinal randomized controlled trial comparing the effectiveness of these…
- Conditions
- Post Traumatic Stress Disorder PTSD, Quality of Life, Functional Outcome, Complex Post-Traumatic Stress Disorder
- Trial name
- NCT06691347
- Testing
- Eye movement desensitization and reprocessing, Cognitive therapy for PTSD
- Where
- Norway
- Volunteers
- 270 people
- Sponsor
- Vestre Viken Hospital Trust
Resting Heart Rate, Blood Glucose Control
Assessing the Effects of Cool Roofs on Indoor Environments and Health in Colima, Mexico
Ambient air temperatures in Mexico have broken record highs in 2024. Solutions are needed to build heat resilience in communities and adapt to increasing heat from climate change.
- Conditions
- Resting Heart Rate, Blood Glucose Control, Depression, Heat-related Symptoms
- Trial name
- REFLECT (NCT06834893)
- Testing
- Cool roof
- Where
- Mexico
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Aditi Bunker
Sickle Cell Disease
Implications of a Paediatrician-psychologist Tandem for Sickle Cell Disease Care and Impact on Cognitive Functioning
Sickle cell disease (SCD) necessitates a paediatric treatment plan that considers the influence of psychological, family and intercultural factors.
- Trial name
- NCT03975699
- Testing
- Assessment of psychological repercussions of SCD
- Volunteers
- 155 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild