Clinical trials: Cognitive Function in Elderly
Cognitive Function
Promoting Mental Acuity in Elderly Populations Through Incentive for Technology Use
In this between-subject randomized controlled trial the investigators will test the impact of three novel structured financial incentives: atomistic, altruistic and team-based.
- Trial name
- NCT00805259
- Testing
- Financial incentives
- Where
- United States
- Volunteers
- 312 people, healthy volunteers welcome
- Sponsor
- Carnegie Mellon University
Postoperative Delirium, Postoperative Recovery in Elderly Patients
Recovery After Upper Extrimety Surgery
The goal of this randomized clinical trial is to determine whether Bispectral Index (BIS)-guided general anesthesia improves postoperative cognitive recovery and overall quality of recovery in adults undergoing elective hand or…
- Conditions
- Postoperative Delirium, Postoperative Recovery in Elderly Patients, Postoperative Cognitive Dysfunction (POCD)
- Trial name
- Recovery (NCT07714928)
- Testing
- BIS-Guided General Anesthesia, Clinically Guided General Anesthesia
- Where
- Sweden
- Volunteers
- 112 people
- Sponsor
- Region Örebro County
Quality of Life, Surgery
Determination of the Effect of Puzzle Use in Elderly Patients
The aim of this study is to determine the effects of the use of a simple, reliable and cost-effective puzzle on post-operative cognitive function changes, postoperative recovery, and quality of life using questionnaires and…
- Conditions
- Quality of Life, Surgery, Postoperative Confusion, Cognitive Dysfunction
- Trial name
- NCT05796830
- Testing
- Puzzle application
- Volunteers
- healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Ischemic Heart Disease, Myocardial Infarction
Polyamine Treatment in Elderly Patients With Coronary Artery Disease
The present study is testing spermidine treatment in elderly patients with coronary artery disease. The study is a randomized, double-blind, placebo-controlled, two-armed, parallel-group, single centre, clinical study.
- Conditions
- Ischemic Heart Disease, Myocardial Infarction, Cardiovascular Diseases, Hypertensive Heart Disease
- Trial name
- PolyCAD (NCT06186102)
- Testing
- Spermidine
- Where
- Denmark
- Volunteers
- 187 people
- Sponsor
- University of Aarhus
Memory Decline, Cognitive Decline
Anti-inflammatory Probiotics in Cognitive Functioning
The goal of this study is to explore the potential impact of an anti-inflammatory probiotic mixture of psychobiotics including Bifidobacterium longum Rosell®-175 and Lactobacillus helveticus Rosell®-52 on cognitive functions in…
- Conditions
- Memory Decline, Cognitive Decline, Cognitive Aging
- Trial name
- CoProM (NCT07165977)
- Where
- Poland
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Social Sciences and Humanities, Warsaw
Mild Cognitive Impairment (MCI)
The Effects of Single Baduanjin and Elastic Band Exercises on VSWM in Elderly Individuals With MCI
Previous studies have confirmed that both acute (single) and long-term various exercise interventions can significantly improve the cognitive function of individuals with MCI.
- Trial name
- NCT07656480
- Testing
- baduanjin exercise, elastic band exercises
- Volunteers
- 60 people
- Sponsor
- qiu chen
Delirium, Postoperative, Anesthesia
Depth of Anesthesia on Postoperative Delirium and Cognitive After Surgery
The goal of this clinical trial (Balanced-2 study) is to compare light to deep general anesthesia using widely available brain monitors, to see if 'light' anesthesia could reduce rates of delirium, cognitive decline, and…
- Conditions
- Delirium, Postoperative, Anesthesia, Surgery-Complications, Cognition Disorder
- Trial name
- Balanced-2 (NCT06268080)
- Testing
- Depth of anesthesia titration using pEEG
- Where
- 3 sites in New Zealand
- Volunteers
- 2,766 people
- Sponsor
- Auckland City Hospital
Cognitive Decline
Effects of Multidomain Intervention on Cognitive Function in Community-dwelling Elderly
The aging population has contributed to an increase in cognitive decline. To mitigate the rise in the dementia population, it is crucial to prevent cognitive decline in older adults with normal functioning, subjective cognitive…
- Trial name
- NCT06180161
- Testing
- multidomain intervention
- Where
- Taiwan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Frail Elderly
Cognitive Function and Prevalence of Amyloid Marker in Frail Older Adults
The current study seeks to examine the prevalence of amyloid pathology, among patients referred to the Toulouse Geriatric Frailty Clinic presenting objective memory impairment.
- Trial name
- COGFRAIL (NCT03129269)
- Testing
- MRI and PET scan
- Where
- France
- Volunteers
- 344 people
- Sponsor
- University Hospital, Toulouse
Cognitive Disorder
A Mixed Intervention to Improve Resilience for Patient With Neurocognitive Disorders
The study aims to test a program combining cognitive behavioral therapy techniques, positive psychology techniques, mindfulness meditation and yoga, in order to improve resilience in patient with minor cognitive disorder.
- Trial name
- RESILIENCE (NCT06801171)
- Testing
- cognitive stimulation, mixed intervention
- Where
- France
- Volunteers
- 90 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Frailty
Effects of Low-Speed and High-Speed Resistance Training Programs on Frailty Status
The present study refers to a three-arm randomized controlled trial that investigated the effects of two types of RT on frailty status, physical performance, cognitive function, and blood pressure of prefrail and frail older…
- Trial name
- RTF (NCT04868071)
- Testing
- Physical Exercise
- Where
- 2 sites in Brazil
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Chewing Problem, Cognitive Decline
Cognitive Changes and Neural Correlates After Rehabilitation of Masticatory Function in Elderly -an Intervention Study
Today in elderly tooth loss and loss of oral function is widespread, but it is an underexplored modifiable risk factor potentially contributing to the development of dementia.
- Conditions
- Chewing Problem, Cognitive Decline, Magnetic Resonance Imaging, Degenerative; Dementia
- Trial name
- NCT04458207
- Testing
- Oral prosthetic rehabilitation
- Where
- 2 sites in Sweden
- Volunteers
- 80 people
- Sponsor
- Folktandvården Stockholms län AB
Sarcopenia, Frailty at Older Adults
Targeting Sarcopenia and Frailty: Multicomponent Exercise With Focal Muscle Vibration
This study aimed to evaluate the efficacy of multicomponent exercises (aerobic exercises, strength exercises, and balance exercises), individualized with the application of a focal muscle vibration machine at the lower…
- Conditions
- Sarcopenia, Frailty at Older Adults, Cognitive Impairment, Adherence
- Trial name
- NCT07049809
- Testing
- Focal Muscle Vibration, Multicomponent Exercise
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Aging
Stretching and Yoga Exercise Study
The investigators propose to test the effects of an 8-week supervised, site-based, group yoga intervention on cognition and functional fitness in older adults.
- Trial name
- SAYExercise (NCT01650532)
- Testing
- Yoga Condition, Stretching Condition
- Where
- United States
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Cognitive Impairment, Dementia
Older Adults With Cognitive Impairment Doing Sit to Stands, Walking in Transitional Care Programs: A Feasibility Study
The goal of this intervention study is to test the effects of a nurse-led mobility intervention (known as the OASIS Walking Intervention (Older Adults performing Sit to Stands and Walking Intervention)) in older adults with…
- Conditions
- Cognitive Impairment, Dementia, Delirium, Functional Decline
- Trial name
- OASIS (NCT06150339)
- Testing
- OASIS Walking Intervention
- Where
- 2 sites in Canada
- Volunteers
- 6 people
- Sponsor
- University Health Network, Toronto
Idiopathic Parkinson's Disease, Multiple Sclerosis
Online Cognitive Training in PD, MS and Depressed Patients Treated With Electroconvulsive Therapy
In Parkinson's disease, Multiple Sclerosis and depressed patients treated with electroconvulsive therapy, cognitive dysfunction is prevalent. However, treatment of these dysfunctions is in its infancy.
- Conditions
- Idiopathic Parkinson's Disease, Multiple Sclerosis, Elderly Post Electric Convulsive Therapy
- Trial name
- NCT02525367
- Testing
- Online cognitive training, Active control condition
- Where
- Netherlands
- Volunteers
- 28 people
- Sponsor
- Amsterdam UMC, location VUmc
Cognitive Impairment, Dementia
Determinants of Cognitive Impairment Among Geriatrics
This study aims to explore the determinants of cognitive impairment among Indonesian geriatrics in an Old Age Home.
- Conditions
- Cognitive Impairment, Dementia, Hearing Impairment, Vision Impairment and Blindness
- Trial name
- NCT03669536
- Where
- Indonesia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Tarumanagara University
Geriatric Population, Cognitive Ability
The Cognitive-Functional Relationship in Geriatric Hand-Forearm Injuries
Considering the complex structure of hand-forearm injuries and the long rehabilitation process, it is important to investigate factors associated with recovery in geriatric individuals.
- Conditions
- Geriatric Population, Cognitive Ability, Functional Abilities, Hand Injuries
- Trial name
- NCT07379229
- Testing
- Questionnaire and Physical Exam
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Pamukkale University
Stroke, Chronic Stroke
Vitality: Promoting Cognitive Function in Older Adults With Chronic Stroke
The investigators will conduct a randomized controlled trial study to provide preliminary evidence of efficacy of exercise training or a complex mental and social activities program for improving cognitive function in older…
- Trial name
- Vitality (NCT01916486)
- Testing
- Exercise training, Complex mental and social activities, Control: stretching and relaxation program
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- University of British Columbia
Cognition, Sedation
Cognitive Function in Geriatric Colonoscopy Patients
Procedures such as colonoscopy cause discomfort and pain and are therefore performed under sedation and analgesia. Although patients aged 65 and older frequently undergo colonoscopy procedures, it is unclear to what extent the…
- Conditions
- Cognition, Sedation, Geriatric Anesthesia, Frailty
- Trial name
- NCT07384169
- Testing
- Propofol Group, Dexmedetomidine group
- Where
- Turkey (Türkiye)
- Volunteers
- 164 people
- Sponsor
- Ankara City Hospital Bilkent