Clinical trials: Cognitive Functioning, open to volunteers
Mild Cognitive Impairment, Older Adults
Virtual Reality Cognitive Training for Older Adults With Mild Cognitive Impairment
This study aims to (1) develop and assess the feasibility of a fi-VRCT program based on IADL for older adults with MCI, (2) implement and evaluate the effectiveness of the fi-VRCT program based on IADL in older adults with MCI…
- Trial name
- NCT06392412
- Testing
- fi-VR Cognitive Training, Traditional Cognitive Training
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Da-Yeh University
Coma, Cardiac Arrest
Combined Whole-brain Structural and Functional MRI for the Prediction of Neurological Recovery After Cardiac Arrest
To assess the performance of a predictive model resulting from the analysis of sMRI/fMRI/contrast-enhanced MRI-derived personalized connectomic data, as compared with standard predictors (clinical examination, electrophysiology…
- Conditions
- Coma, Cardiac Arrest, Disorder of Consciousness, Neurologic Disorder
- Trial name
- ARISE (NCT06617377)
- Testing
- advanced whole-brain sMRI/fMRI/contrast-enhanced MRI scan
- Where
- France
- Volunteers
- 263 people
- Sponsor
- University Hospital, Toulouse
Schizophrenia, Treatment Resistant Schizophrenia
Effectiveness of Exercise Alone and tDCS+Exercise on Cognitive Function Improvement in Patients With Treatment Resistant Schizophrenia
Cognitive impairment is a major determinant of disability in schizophrenia. Aerobic exercise improves global cognition in schizophrenia, particularly working memory and attention/vigilance.
- Conditions
- Schizophrenia, Treatment Resistant Schizophrenia, Cognitive Impairment
- Trial name
- TRACE (NCT07404319)
- Testing
- Aerobic Exercise, Stretching/Education Control, Active tDCS
- Where
- Hong Kong
- Volunteers
- 160 people
- Sponsor
- Kit Wa Chan
At Risk for AD-dementia, With Subjective Cognitive Decline, At Risk for Cognitive Decline
High-Velocity Resistance Training for Brain Blood Flow and Cognitive Function in Older Adults
The goal of this clinical trial is to learn whether a 12-week high-velocity resistance training program can improve brain blood flow and thinking skills in adults ages 60 to 79 who are at higher risk for Alzheimer's disease and…
- Trial name
- NCT07444554
- Testing
- High-Velocity Resistance Training
- Volunteers
- 60 people
- Sponsor
- University of Illinois Chicago
Aging
The Effect of NAD Supplementation on Brain Vascular Health in Aging
Daily consumption of one of the forms of Vitamin B3, the Nicotinamide Riboside (NR), energizes the body and combats cellular aging. This study is designed to test whether NR can also improve brain health and memory.
- Trial name
- NCT05483465
- Testing
- Nicotinamide riboside
- Where
- United States
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
ADHD - Attention Deficit Disorder With Hyperactivity
Brain Stimulation and Attention Control in Children With ADHD
The goal of this clinical trial is to learn if brain stimulation can help children ages 6 to 12 with attention-deficit/hyperactivity disorder (ADHD) improve their attention and self-control.
- Trial name
- NCT07182344
- Testing
- Intermittent Theta Burst Stimulation to Right DLPFC
- Where
- 2 sites in Kazakhstan
- Volunteers
- 40 people
- Sponsor
- Neurolab Plus
Bipolar Disorder, Bipolar and Related Disorders
Targeted Alternating Current and Cognitive Training Intervention for Cognitive Control in Bipolar Disorders
This study is testing whether a type of gentle brain stimulation, combined with computer-based brain training exercises, can help improve thinking skills in Veterans with bipolar disorder.
- Conditions
- Bipolar Disorder, Bipolar and Related Disorders, Veterans, Suicide
- Trial name
- TACTIC-BD (NCT07845409)
- Testing
- Soterix 1x1 tES mini-CT
- Where
- United States
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Cerebral Small Vessel Disease, Cognitive Impairment
Remote Ischemic Conditioning for Cognitive Impairment in Cerebral Small Vessel Disease
This randomized, double-blind, sham-controlled trial aims to evaluate the effect of remote ischemic conditioning (RIC) on cognitive function in patients with cerebral small vessel disease-related mild cognitive impairment.
- Trial name
- RIC-CSVD (NCT07317557)
- Testing
- Remote ischemic conditioning using IPC-906 device
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Jiangsu Province Nanjing Brain Hospital
Mild Cognitive Impairment in Middle-aged Adults
Deafness and Cognition in Middle-aged Adults
A mild cognitive impairment was observed in 50% of cochlear implant candidates aged 65 years and over, compared to 5-19% in general population. No studies analysed cognition in patients younger than 65 years.
- Trial name
- SURDICOG (NCT05149742)
- Testing
- Cognitive and audiometry evaluation
- Where
- France
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Blood Loss Anemia, Extracorporeal Membrane Oxygenation Complication
Red Blood Cell Transfusion in ECMO - A Feasibility Trial
Extracorporeal Membrane Oxygenation (ECMO) is an invasive and resource intense treatment used to support critically ill patients who have suffered severe cardiac arrest, cardiac failure or respiratory failure (including severe…
- Conditions
- Blood Loss Anemia, Extracorporeal Membrane Oxygenation Complication, Disability Physical, Cognitive Ability, General
- Trial name
- ROSETTA (NCT05814094)
- Testing
- Red Blood Cell Transfusion
- Where
- 2 sites in Australia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Australian and New Zealand Intensive Care Research Centre
Convulsion, Non-Epileptic
Retraining and Control Therapy (ReACT)- Adults
The purpose of this study is to assess sense of control and catastrophic symptom expectations as targets for Retraining and Control Therapy (ReACT- an intervention focused on changing behaviors and thoughts) for treatment of…
- Trial name
- ReACT (NCT06570954)
- Testing
- ReACT
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Alabama at Birmingham
Avoidant/Restrictive Food Intake Disorder, Dyspepsia
Exposure-Based CBT for Avoidant/Restrictive Food Intake in Functional Dyspepsia
Randomized controlled trial of an exposure-based behavioral treatment (CBT) in adults with functional dyspepsia who meet criteria for avoidant/restrictive food intake disorder (ARFID) with weight loss.
- Conditions
- Avoidant/Restrictive Food Intake Disorder, Dyspepsia, Feeding and Eating Disorders, Cognitive Behavioral Therapy
- Trial name
- NCT05587127
- Testing
- Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Massachusetts General Hospital
Heart Failure, Mild Cognitive Impairment
Impact of Yoga on Cognitive Function
Mild cognitive impairment is highly prevalent in patients with heart failure and results in poor well-being and quality of life.
- Trial name
- NCT06434168
- Testing
- Yoga intervention, Control condition
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Auburn University
Cognitive Impairment, Depression, Anxiety
intErnet-based iNterventions FOR Cardiac arrEst suRvivors
This randomized clinical trial will test whether an internet-based lifestyle intervention administered through a web app can foster Health Related Quality of Life in patients who survived an out-of-hospital cardiac arrest and…
- Conditions
- Cognitive Impairment, Depression, Anxiety, Cardiac Arrest, Quality of Life
- Trial name
- ENFORCER (NCT06395558)
- Testing
- Lifestyle intervention
- Where
- 2 sites in Italy
- Volunteers
- 106 people
- Sponsor
- Azienda Usl di Bologna
Type 2 Diabets Mellitus, Cognitive Ability, General
Cilostazol-Ginkgo for Cognitive Function in Elderly Diabetes
This exploratory pilot study aims to evaluate the cognitive improvement effects of combination therapy with cilostazol (200 mg) and ginkgo biloba extract (160 mg) in elderly patients with type 2 diabetes mellitus.
- Trial name
- NCT06989697
- Testing
- Cilostazol / Ginko Leaf Dried Ext.
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Seoul National University Bundang Hospital
Cognitive Impairment, Hematologic Neoplasms
Cognitive Training Intervention and Attitudes Towards Genetics
A pilot study to evaluate feasibility of enrollment of patients in an intervention to improve neurocognitive function in hematopoietic cell transplantation (HCT) survivors using the cognitive training Lumosity program.
- Conditions
- Cognitive Impairment, Hematologic Neoplasms, Hematopoietic Cell Transplant
- Trial name
- cTAG (NCT03094026)
- Testing
- Lumosity, Lumosity (waitlist control)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Alabama at Birmingham
Low Back Pain
Activity Management Training in Low Back Pain
The individuals participating in the study will be asked to fill in the Body Awareness Scale, Canadian Activity Performance Measure, Pain Activity Patterns Scale, Cognitive Status Scale, and Fatigue Severity Scale.
- Trial name
- NCT07061743
- Testing
- activity management training
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Çankırı Karatekin University
Cognition
The Effect of Pistachio-Rich Breakfast Meals on Cognitive Function in Healthy Older Adults
This study aims to investigate the effect of a breakfast meal containing varying serving sizes (doses) of pistachio nuts on cognitive function throughout the course of the day in healthy ageing adults aged 65-80.
- Trial name
- PACVAN (NCT06900452)
- Testing
- 0.5 serving of pistachios, 1 serving of pistachios, 2 servings of pistachios
- Where
- United Kingdom
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Reading
Chronic Myeloproliferative Disorders, Cognitive/Functional Effects
Registry of Older Patients With Cancer
RATIONALE: Gathering information about older patients with cancer may help the study of cancer in the future. PURPOSE: This research study is gathering information from older patients with cancer into a registry.
- Conditions
- Chronic Myeloproliferative Disorders, Cognitive/Functional Effects, Leukemia, Lymphoma
- Trial name
- NCT01137825
- Where
- 7 sites in United States
- Volunteers
- 3,000 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Cognitive Performance, Academic Performance
Acute Effects of Active Breaks and Physically Active Learning in University Students
This multicenter randomized crossover study will examine the acute effects of four classroom break conditions on executive functions, immediate academic performance, perceived exertion, and interest-enjoyment in university…
- Trial name
- PAL UNI (NCT07809750)
- Testing
- Sedentary Academic Review, Active Break, Physically Active Learning
- Where
- Spain
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid