Clinical trials: Cognitive Investigation
Schizophrenia, Schizoaffective Disorder
Cognitive Remediation Therapy Within a Secure Forensic Setting
This clinical trial tests the feasibility, effectiveness and patient satisfaction with cognitive remediation therapy for patients diagnosed with schizophrenia or schizoaffective disorder within a forensic hospital.
- Conditions
- Schizophrenia, Schizoaffective Disorder, Cognitive Deficits
- Trial name
- NCT02360813
- Testing
- Cognitive Remediation Therapy, Treatment as usual
- Where
- Ireland
- Volunteers
- 65 people
- Sponsor
- Central Mental Hospital
Thalassemia
Assessment of Cognitive Function and Quality of Life in Thalassemic Children at Sohag University Hospital
Thalassemia syndromes are a heterogeneous group of single gene disorders, inherited in an autosomal recessive manner ,prevalent among all ethnic groups and in almost every country around the world .
- Trial name
- NCT06058260
- Testing
- Pediatric Quality of Life Inventory (questionnaire) and The Stanford-Binet Intelligence Scale fifth edition
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University
Alzheimer's Disease (AD)
A Trial of SHR-1707 Infusion in Patients With Mild Cognitive Impairment Due to Alzheimer's Disease and Mild Alzheimer's Disease
To evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of SHR-1707 in patients with mild cognitive impairment (MCI) due to Alzheimer's disease (AD) and mild AD for 26 weeks.
- Trial name
- NCT06114745
- Testing
- SHR-1707 injection
- Where
- 3 sites in Australia
- Volunteers
- 2 people
- Sponsor
- Atridia Pty Ltd.
Post Concussion Syndrome, Head Injury
Evaluation of Two Treatments for Chronic Post Concussion Syndrome
This study is designed to investigate factors that are associated with prolonged recovery from mild head injury. The investigators are particularly interested in defining the impact of anxiety related variables, such as health…
- Trial name
- NCT00871884
- Testing
- Psychoeducation, Relaxation Training, Interoceptive Exposure
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Simon Fraser University
Antenatal Depression
Internet CBT for Antenatal Depression
Pregnant women in pregnancy week 8-29 screening positive for antenatal depression will be randomized to either choose or to be allotted by chance to different forms of diagnostic assessment; i.e.
- Trial name
- NCT05533138
- Testing
- Therapist Guided Internet-CBT for antenatal depression, Therapist Guided Internet-CBT for antenatal depression and perinatal extra support., Diagnostic assessment by telephone, video or face-to face - Allocation by chance
- Where
- Sweden
- Volunteers
- 415 people
- Sponsor
- Karolinska Institutet
Multiple Sclerosis, Mild Cognitive Impairment
Effects of a CT-100 DiNaMo Component on Cognitive Functioning and Mood Symptoms
CT-100 is a platform that provides an interactive, software based therapeutic component that may be used as part of a multimodal treatment in supplementary or standalone prescription or nonprescription software-based digital…
- Conditions
- Multiple Sclerosis, Mild Cognitive Impairment, Cancer
- Trial name
- NCT05438147
- Testing
- CT-100 DiNaMo, Care-as-Usual
- Where
- United States
- Volunteers
- 114 people
- Sponsor
- Click Therapeutics, Inc.
Cognitive/Functional Effects, Depression
Physical and Mental Assessment of Older Patients With Newly Diagnosed Acute Myeloid Leukemia
RATIONALE: Learning about physical ability and mental function over time in older patients with acute myeloid leukemia may help doctors learn about the long-term effects of treatment and plan the best treatment.
- Conditions
- Cognitive/Functional Effects, Depression, Leukemia
- Trial name
- NCT00499785
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Wake Forest University Health Sciences
Mild Cognitive Impairment
Effect of Consuming a Mixture of Extracts and DHA on the Mild Cognitive Impairment
The objective of this trial is to evaluate the effect of the consumption of a mixture of extracts and DHA on the mild cognitive impairment.
- Trial name
- NCT06254040
- Testing
- mixture of extracts and DHA
- Where
- Spain
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Biosearch S.A.
Cognitive Functioning of Healthy Individuals
Norms Expansion and Validation for IntelliSpace Cognition
This study aims to expand the normative dataset for Philips IntelliSpace Cognition to include ages 18-49 and 80+ and aims to validate two new digital tests.
- Trial name
- NCT04729257
- Testing
- Philips IntelliSpace Cognition (ISC)., Paper-Pencil Tests.
- Where
- United States
- Volunteers
- 508 people, healthy volunteers welcome
- Sponsor
- Philips Clinical & Medical Affairs Global
Physical Activity
Investigations of the Effects and Associated Neural Mechanisms of Different Exercise in People With Metabolic Syndrome
Metabolic syndrome (MetS) is a risk for many chronic diseases of middle-aged and older adults. Hence, prevention and treatment of MetS is a crucial global health issue.
- Trial name
- NCT05672940
- Testing
- Aerobic plus resistance training, Stretching plus breathing training
- Where
- Taiwan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Aging, Cognitive Decline
Evaluation of the Online Memory & Aging Program and Online Goal Management Training
The current study is designed to test the effectiveness of online programs for memory and executive functions in healthy aging. The investigators are testing online adaptations of two cognitive interventions that have been…
- Trial name
- NCT03602768
- Testing
- Goal Management Training, Memory & Aging Program, Cambridge Brain Sciences
- Where
- Canada
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Baycrest
Muscle Strength, Cognitive Function Assessment
Omega-3 Fatty Acids and Muscle Strength
The purpose of the study is to evaluate the effects of 12-week supplementation with algae-derived DHA combined with strength training on muscle strength, neuromuscular parameters, post-exercise inflammation and cognitive…
- Trial name
- NCT07763574
- Testing
- Effects of Strength Training Combined With Omega-3s derived from algae on Muscle Strength and Cognitive Functions in adults, Effects of Strength Training Combined With Omega-3s derived from fish on Muscle Strength and Cognitive Functions in adults, Effects of Omega-3s derived from algae on Muscle Strength and Cognitive Functions in adults
- Where
- Poland
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Gdansk University of Physical Education and Sport
Brain Injuries
The Value of Multimodal MR Imaging in Cognitive Assessment of Patients With Moderate Traumatic Brain Injury
The goal of this observational study is to learn about in The value of multimodal MR Imaging in cognitive assessment of patients with moderate traumatic brain injury.
- Trial name
- NCT06099210
- Testing
- Glasgow coma scale
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Cognitive Function, Mood
The Effects of Caffeine and L-theanine Both Alone and in Combination on Cerebral Blood Flow, Cognition and Mood
Although the beneficial effects of caffeine on cognition and mood have been reported in a number of studies, relatively few studies have looked at the effects of caffeine in combination with other phytonutrients despite the fact…
- Trial name
- NCT00981955
- Testing
- Caffeine and L-theanine
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Low Back Pain, Pain
Evaluation of Stepped Care for Chronic Pain in Iraq/Afghanistan Veterans (ESCAPE)
The purpose of this study is to determine if a stepped-care intervention makes pain symptoms better and reduces activity limitations because of pain. Our two primary hypotheses are that in OIF/OEF veterans with chronic pain: 1.
- Conditions
- Low Back Pain, Pain, Pain, Intractable
- Trial name
- ESCAPE (NCT00386243)
- Testing
- Cognitive behavioral therapy, Pain self-management program, Co-Analgesic Therapy
- Where
- United States
- Volunteers
- 242 people
- Sponsor
- VA Office of Research and Development
Dementia, Alzheimer Disease
A Study to Evaluate the Efficacy and Safety of Galantamine in Patients With Mild Cognitive Impairment
The purpose of this study is to evaluate the efficacy and safety of galantamine treatment in patients with mild cognitive impairment.
- Trial name
- NCT00236574
- Testing
- Galantamine hydrobromide
- Volunteers
- 974 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Focal Epilepsy, Temporal Lobe Epilepsy
Spatial Scene Recognition Memory in Epilepsy Surgery
This study investigates the anatomical and physiological basis of spatial scene recognition memory in patients with temporal lobe epilepsy and temporal lobe lesions.
- Conditions
- Focal Epilepsy, Temporal Lobe Epilepsy, Medically Refractory Epilepsy, Memory Disorders
- Trial name
- NCT07580183
- Testing
- Virtual Tour Recognition Memory Task, Intracranial EEG Recording with Research Electrodes (Aim III only), MRI Neuroimaging and Neuropsychological Assessment (Aim I)
- Where
- 2 sites in United States
- Volunteers
- 620 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Cognitive Function
Efficacy and Safety of Hydrolysed Red Ginseng Extract on Improvement of Cognitive Function
This study was the evaluate the efficacy and safety of hydrolysed red ginseng extract on the improvement of Cognitive Function
- Trial name
- NCT04184388
- Testing
- Hydrolysed Red Ginseng Extract
- Where
- South Korea
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Chonbuk National University Hospital
Nicotine Dependence
Human Laboratory Study Of Varenicline in Smokers
The purpose of this study is to test the ways that a drug called varenicline helps smokers to quit smoking. Varenicline is also called Chantix® and is approved by the United States Food and Drug Administration (FDA) to help…
- Trial name
- NCT00709696
- Testing
- Varenicline
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Cognitive Disorders
Safety, Tolerability and Pharmacokinetics of GSK1034702 in Healthy Subjects
This is a First Time in Human Study to assess the safety, tolerability and pharmacokinetics of single doses of GSK1034702 in healthy subjects.
- Trial name
- NCT00743405
- Testing
- GSK1034702
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
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