Clinical trials: Cognitive Investigation
Cognitive Fatigue
Immersive VR Environments to Induce and Evaluate Cognitive Fatigability
Background: Immersive virtual reality (VR) technology is used by researchers to measure how people respond to complex stimuli in a controlled environment.
- Trial name
- NCT04883359
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- National Institute of Nursing Research (NINR)
Cognitive Change, Mood Change
The Cognitive Effects of 'Brainwaves' Supplementation in Cognitively Intact Older Adults
This study investigated the effects of a proprietorial herbal supplement, Turmeric Brainwave (now Mind focus), on cognition, mood and the microbiome in older adults experiencing subjective memory decline, following 90 days…
- Conditions
- Cognitive Change, Mood Change, Microbial Colonization
- Trial name
- NCT05504668
- Testing
- Turmeric Brainwave
- Where
- United Kingdom
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Alzheimer Disease and Related Dementias, Cognition
Home-Based Brain Stimulation for Motoric Cognitive Risk Syndrome
The objective of this study is to determine the effects of a 6-month, home-based personalized transcranial direct current stimulation (tDCS) intervention targeting the left dorsolateral prefrontal cortex on cognitive function…
- Conditions
- Alzheimer Disease and Related Dementias, Cognition, Mobility Disability
- Trial name
- TDCS4MCR (NCT06821568)
- Testing
- Personalized Transcranial Direct Current Stimulation (tDCS)
- Where
- 2 sites in United States, Israel
- Volunteers
- 128 people
- Sponsor
- Hebrew SeniorLife
Obesity (Disorder), Obesity and Obesity-related Medical Conditions
Evaluation of Cognitive Improvement After Bariatric Surgery Using a Virtual Reality Program and the Neuropsi Neuropsychological Battery
Background: Obesity is a chronic, systemic, and multifactorial disease affecting populations worldwide, with projections indicating a 50% increase by 2035.
- Trial name
- CognitiveBS (NCT07229924)
- Testing
- Bariatric Surgery
- Where
- 2 sites in Canada, Mexico
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Hospital General de México Dr. Eduardo Liceaga
Alzheimer's Dementia
Safety and Efficacy Study of Magnetic Fields to Treat Alzheimer's Disease
The purpose of this study is to determine if low level magnetic fields can help to improve memory in patients diagnosed with Alzheimer's dementia.
- Trial name
- NCT01195389
- Testing
- Resonator
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- pico-tesla Magnetic Therapies, LLC
Cognitive Impairment, Cognitive Impairment, Mild
Comparative Evaluation of Immediate vs Progressive Standing Dual Task Training in Elderly With Mild and Moderate Cognitive Impairment
older adults with mild and moderate cognitive impairment. compare immediate vs progressive standing dual-task training. assess balance, cognition, executive function, mobility, and quality of life.
- Conditions
- Cognitive Impairment, Cognitive Impairment, Mild, Moderate Cognitive Impairment
- Trial name
- NCT07764250
- Testing
- Immediate standing dual task training, progressive standing dual task training
- Where
- Pakistan
- Volunteers
- 96 people
- Sponsor
- Shifa Tameer-e-Millat University
Anxiety, Depression
Anxiety With Cancer in the Elderly (ACE): A Cognitive-behavioral Intervention
The purpose of this study is to examine the feasibility and acceptability of and patient adherence to a telephone-administered cognitive-behavioral therapy intervention for anxiety in older adults (65 years and older) with cancer…
- Conditions
- Anxiety, Depression, Quality of Life
- Trial name
- NCT02747160
- Testing
- Managing Anxiety from Cancer (MAC)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Postoperative Cognitive Dysfunction (POCD)
Cohort Study of Postoperative Cognitive Dysfunction After Off-Pump Coronary Artery Bypass Grafting
This prospective cohort study aims to investigate postoperative cognitive dysfunction in patients undergoing off-pump coronary artery bypass grafting. Eligible patients will be enrolled before surgery and followed after surgery.
- Trial name
- OPCAB-POCD (NCT07643194)
- Testing
- Off-Pump Coronary Artery Bypass Grafting
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Beijing Anzhen Hospital
Healthy
Effects of Supradyn® Energy 3RDA on Fatigue/Stress, Substrate Metabolism During Exercise and Demanding Cognitive Tasks
Investigation of the acute and chronic effects of Supradyn® Energy 3RDA on subjective ratings of 'fatigue/stress', substrate metabolism and blood biomarkers of recovery, as a consequence of exercise and metabolically demanding…
- Trial name
- NCT03003442
- Testing
- Supradyn® Energy 3RDA
- Where
- United Kingdom
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Hypertension
Evaluation of the Antihypertensive Effect of Hyzaar(R) and Cognitive Function of Hypertensive Patients (0954A-322)
Evaluate the antihypertensive and neuroprotective effects of Hyzaar(R) in elderly subjects in comparison with Natrilix(TM).
- Trial name
- NCT00398541
- Testing
- losartan potassium (+) hydrochlorothiazide
- Volunteers
- 41 people
- Sponsor
- Organon and Co
Alzheimer Disease, Mild Cognitive Impairment
A Longitudinal Evaluation of a Radiotracer for Use in Tau Tracking
This is a longitudinal, observational study evaluating the imaging characteristics of the tau PET radioligand [18F]MK-6240 in Alzheimer's disease (AD), Mild Cognitive Impairment (MCI) and Healthy Volunteer (HV) subjects.
- Trial name
- NCT03919669
- Testing
- All Subjects
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Suicide, Attempted
A Comparison of Brief Cognitive Behavioural Therapy (CBT) and the Attempted Suicide Short Intervention Program
The aim of this project is to assess if adding one of two structured suicide specific psychological interventions to a standardised clinical care approach improves outcomes for consumers presenting to a Mental Health Service with…
- Trial name
- ASSIP (NCT04072666)
- Testing
- Attempted Suicide Short Intervention Program (ASSIP), Cognitive Behavioural Therapy (CBT), Suicide Prevention Pathway (SPP)
- Where
- Australia
- Volunteers
- 411 people
- Sponsor
- Gold Coast Hospital and Health Service
Postoperative Cognitive Dysfunction, Delirium, Postoperative
Evaluation of the Predictive Impact of Serum S100B and S100B Polymorphisms on Postoperative Cognitive Dysfunction and Delirium
Postoperative cognitive disorders, including postoperative cognitive dysfunction (POCD) and postoperative delirium (POD), are common complications following surgery and anesthesia, particularly in vulnerable patient populations.
- Trial name
- NCT07509372
- Testing
- Perioperative Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 137 people
- Sponsor
- Ankara University
Cognitive Impairment
The Effect of Exercise on Cognition in Older Adults At-risk for Diabetes: A Feasibility Pilot Study
Older adults with type 2 diabetes experience cognitive decline and are at higher risk for developing dementia. Consequently, older adults at-risk for developing type 2 diabetes (based on body mass, glucose levels) are at higher…
- Trial name
- NCT03254381
- Testing
- Resistance Training, Balance and Tone Training
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- Western University, Canada
Dementia With Lewy Bodies, Lewy Body Disease
Alpha tACS in Dementia With Lewy Bodies
Brain oscillations are ubiquitous in the human brain and have been implicated in cognitive and behavioral states defined in precisely tuned neural networks.
- Trial name
- Alpha-DLB (NCT05188105)
- Testing
- Alpha tACS (12 Hz) over the occipital cortex
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
Obesity
Evaluation of the Healthy Lifestyle Program on Cognitive Outcomes
The goal of this study is to conduct a program of pilot research aimed at evaluating the effect of an intensive lifestyle intervention on cognitive functioning in older adults with obesity and or obesity and sarcopenia.
- Trial name
- NCT03926481
- Testing
- Evaluate Healthy Lifestyle Program on cognitive outcomes
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Pneumonia, COPD Asthma
Development and Evaluation of Clinical Pharmacy Services in Respiratory Diseases
Clinical pharmacists in the healthcare system are experts in therapeutics and the use of drugs. They routinely provide medication reviews and recommendations to patients and healthcare professionals.
- Conditions
- Pneumonia, COPD Asthma, COPD Exacerbation
- Trial name
- NCT05564156
- Testing
- Intervention groups
- Where
- Turkey (Türkiye)
- Volunteers
- 168 people
- Sponsor
- Bezmialem Vakif University
Mild Cognitive Impairment (MCI)
Evaluation of a PMT Rehabilitation Nursing Plan for the Older Adults With MCI to Promote Cognitive Health
With the aging of the population, the number of older adults with mild cognitive impairment (MCI) has increased year by year, which has caused serious social and family burdens.
- Trial name
- NCT07089654
- Testing
- A PMT rehabilitation nursing plan, General rehabilitation nursing
- Where
- 2 sites in China
- Volunteers
- 73 people
- Sponsor
- Jinzhou Medical University
Post Traumatic Stress, Overall Functioning
Randomized Controlled Trial of Supervision Strategies to Improve Clinician Fidelity to Trauma-focused CBT
The primary goal of this study is to examine the impact of varying supervision strategies on clinician fidelity and client outcomes in a community-based setting.
- Conditions
- Post Traumatic Stress, Overall Functioning, Clinician Fidelity, Supervision
- Trial name
- STEPS (NCT01800266)
- Testing
- Supervision Practices of TF-CBT
- Where
- United States
- Volunteers
- 1,280 people
- Sponsor
- University of Washington
Bipolar Disorder
Assessment of Cognitive Functions in Bipolar Patients
Assessment of cognitive function in manic bipolar patient
- Trial name
- NCT04091828
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Assiut University