Clinical trials: Cognitive Investigation
Alzheimer Disease
Patients With Behavioural Symptoms and Hospitalized in Cognitive and Behavioural Units
Cognitive and behavioral units (CBUs) have been created between 2008 and 2012 French National Alzheimer plan for the management of behavior problems of patients suffering from Alzheimer's disease or other related disorders and…
- Trial name
- NCT01901263
- Testing
- patients with alzheimer's disease
- Where
- 3 sites in France
- Volunteers
- 306 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Motor Function, Cognitive Function
Effect on Body Movement and Mental Skills in Patients Who Received Gadolinium-based Contrast Media for Magnetic Resonance Examination Multiple Times Within 5 Years
This study is a postmarketing requirement jointly carried out by four NDA holders (Bayer AG, Bracco, GE Healthcare and Guerbet) and the CRO IQVIA.
- Conditions
- Motor Function, Cognitive Function, Contrast Media
- Trial name
- ODYSSEY (NCT04373564)
- Testing
- Motor Tests, Cognitive Tests, Unenhanced-MRI of the brain
- Where
- 51 sites in United States, Brazil and 6 more
- Volunteers
- 2,076 people
- Sponsor
- Guerbet
Mild Cognitive Impairment, Alzheimer Disease
Specialized Food Plan Based on Individual Physiological Comprehensive Body Assessments Accompanied With Cellular Repair Therapy to Decrease Inflammation Cognitively Impaired Patients
Diet plays a large role in inflammation, oxidative stress and cognition; however, every person's body type, resting metabolic rate, BMI, and inflammation levels vary.
- Trial name
- NCT03630419
- Testing
- Mito-Food Plan, Cellular Repair Therapy
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Perseverance Research Center, LLC
Cognitive Decline
A Study to Evaluate the Safety, Tolerability, and Pharmacodynamics of SDI-118 in Elderly Male and Female Study Participants With Cognitive Decline
This is a multi-center, double-blind, randomized, placebo-controlled study to determine the safety, tolerability, and pharmacodynamics of SDI-118 in a once daily (QD) dosing regimen on elderly male and female study participants…
- Trial name
- NCT05199142
- Testing
- SDI-118
- Where
- 2 sites in Germany, United Kingdom
- Volunteers
- 5 people
- Sponsor
- Syndesi Therapeutics
Burnout, Caregiver
Evaluation of the CBSM Program Online and in Person to Reduce Caregiver Burnout
Professional burnout is a common syndrome among healthcare workers, impacting both their well-being and the quality of care provided .
- Trial name
- Caregiver-CBSM (NCT06626061)
- Testing
- Cognitive Behavioral Stress management in in person group Format, Cognitive Behavioral Stress management Hybrid Format
- Where
- 2 sites in France
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Patients With Recurrent Depressive Disorders
Evaluation of the Impact of the Level of Mindfulness on the Management of Patients With Recurrent Depressive Disorders by the Mindfulness Based Cognitive Therapy ( MBCT ): an Exploratory Study
Mindfulness is both a natural resource of individuals present in all individuals in varying degrees characteristic ability of attention to the experience that unfolds moment by moment without judgment and a practice based on…
- Trial name
- MBCT (NCT02872324)
- Testing
- Procurement questionnaires
- Where
- France
- Volunteers
- 66 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Physical Disability, Cognitive Dysfunction
Evaluation of mediVR-KAGURA Guided Therapy
The objective is to evaluate mediVR-KAGURA guided therapy for the treatments of physical and cognitive dysfunctions regardless of baseline disease in a prospective interventional design.
- Trial name
- NCT04562662
- Testing
- mediVR KAGURA
- Where
- Japan
- Volunteers
- 20 people
- Sponsor
- Japan Society of Clinical Research
Fibromyalgia, Cognitive Dysfunction
Relationship Between Central Sensitization Symptoms and Cognitive Dysfunction in Fibromyalgia
The aim of the study is to investigate the relationship between central sensitization parameters and cognitive dysfunction in patients with fibromyalgia.The main questions it aims to answer are: Do central sensitization symptoms…
- Conditions
- Fibromyalgia, Cognitive Dysfunction, Central Sensitisation
- Trial name
- NCT06948903
- Testing
- Central Sensitization Inventory, The Montreal Cognitive Assessment, Cognitive Symptom Severity Scale-Extended
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Huntington's Disease
Cognitive Assessment Battery (CAB) Beta Study
The overall objective of this study is to identify a 60 minute cognitive battery, for subsequent use in clinical trials, that detects cognitive deficits in early HD and late pre-manifest HD compared to controls, and that has a…
- Trial name
- CAB (NCT01290861)
- Where
- 20 sites in United States, Australia and 2 more
- Volunteers
- 255 people, healthy volunteers welcome
- Sponsor
- CHDI Foundation, Inc.
Cognitive Impairment Associated With Schizophrenia
A Study to Evaluate the Safety and Efficacy of BIIB104 in Participants With Cognitive Impairment Associated With Schizophrenia (CIAS)
The primary objective of the study is to evaluate the efficacy of BIIB104 in participants with CIAS, using the Working Memory Domain of the MATRICS Consensus Cognitive Battery (MCCB).
- Trial name
- TALLY (NCT03745820)
- Testing
- BIIB104
- Where
- 60 sites in United States, Germany and 3 more
- Volunteers
- 195 people
- Sponsor
- Biogen
Nicotine Dependence
Human Laboratory Study Of Varenicline in Smokers
The purpose of this study is to test the ways that a drug called varenicline helps smokers to quit smoking. Varenicline is also called Chantix® and is approved by the United States Food and Drug Administration (FDA) to help…
- Trial name
- NCT00709696
- Testing
- Varenicline
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
(Focus) Posture Effect on Cognitive Performance
Are You Sitting Down: Cognitive Exectutive Function Task Comparison Between Seated and Standing Positions
The aim of this trial has been to explore the effects of self-positioning on cognitive performance in the work environment using a standardized cognitive test battery to evaluate executive function under two conditions: sitting…
- Trial name
- sitstandcef (NCT01641588)
- Testing
- posture: sitting or standing
- Where
- United Kingdom
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Southampton
Intellectual Disability, Mild
Evaluation of CO-OP for Adolescents With Mild Intellectual Disability
Intellectual disability (ID) affects a person throughout life and includes difficulties to manage what is expected in everyday life based on age.
- Trial name
- CO-OPIF (NCT06691698)
- Testing
- The Cognitive Orientation to Daily Occupational Performance Approach
- Where
- 2 sites in Sweden
- Volunteers
- 60 people
- Sponsor
- Örebro University, Sweden
Language, Methylphenidate of Undetermined Intent
Language & Cognitive Control
Catecholamine (CA) neurotransmitters, such as dopamine (DA) and noradrenaline (NA), have long been implicated playing a critical role in cognitive functions, such as working memory (WM), inhibition, learning, and decision making.
- Trial name
- LCCMPH (NCT05272397)
- Testing
- Methylphenidate 20 Mg Oral Tablet, Language Task, Rest Recording
- Where
- Netherlands
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Donders Centre for Cognitive Neuroimaging
Schizophrenia, Impaired Cognition
A 26-Week Extension Study of EVP-6124 (Alpha-7 nAChR) as an Adjunctive Pro-Cognitive Treatment in Schizophrenia Subjects on Chronic Stable Atypical Antipsychotic Therapy
This study is being conducted to further investigate the safety of prolonged exposure to EVP-6124 in subjects with Schizophrenia receiving a stable dose of an atypical antipsychotic who completed double-blind treatment on studies…
- Trial name
- NCT01714713
- Testing
- EVP-6124
- Where
- 128 sites in United States, Argentina and 14 more
- Volunteers
- 830 people
- Sponsor
- FORUM Pharmaceuticals Inc
Alzheimer's Disease
Alzheimer's Disease: Clinical Investigation and Neuroimage Studies Including 18F-PM-PBB3 and 18F-florbetapir (AV-45) PET Examination
Dementia is a common neurodegenerative syndrome in aged population. Alzheimer's disease (AD) is the most common disease. The main pathological findings in AD include senile plaques (SP) and neurofibrillary tangles (NFT).
- Trial name
- PMPBB3/AV45 (NCT04305210)
- Testing
- F-18 PMPBB3, 18F-florbetapir
- Where
- Taiwan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Stroke, Cognitive and Attention Disorders and Disturbances
The RenAtt Method for Diagnosing and Treating Attention Problems After Stroke and Brain Injury, Further Validation of RehAtt® DiSTRO Assessment of Cognitive and Visual Function
Stroke is one of the most common long-term disabilities in the world. Despite better access to more effective acute treatment, WHO reports a prediction of almost a doubling of disability-adjusted life-years (DALYs) in 2050.
- Conditions
- Stroke, Cognitive and Attention Disorders and Disturbances, Digital Health, Screening Strategy
- Trial name
- NCT07762274
- Testing
- Oxford Cognitive Screen
- Where
- 3 sites in Italy, Sweden and 1 more
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Umeå University
Cognitive Impairment, Voice Disorders
Correlation Between Montreal Cognitive Assessment and Voice Therapy Outcomes in the Aging Treatment- Seeking Population
This study will investigate if the performance on the Montreal Cognitive Assessment (MoCA) is associated or predictive of the outcomes in voice, swallowing or upper airway therapy in the older laryngology treatment seeking…
- Conditions
- Cognitive Impairment, Voice Disorders, Voicebox Disorders, Cognitive Decline
- Trial name
- MoCA (NCT05187910)
- Testing
- Speech Therapy, Swallowing Therapy, Upper Airway Therapy
- Where
- 4 sites in United States
- Volunteers
- 57 people
- Sponsor
- University of California, San Francisco
Alzheimer Disease (AD)
The Co-Production and Evaluation of the Computerised Cognitive Assessment for Preclinical Alzheimer's Disease (CoCoA-PAD)
Background. Healthcare professionals can now diagnose the earliest stages of Alzheimer's disease (early-AD) and new drugs are effective at slowing the disease.
- Trial name
- CoCoA-PAD (NCT07598617)
- Where
- 3 sites in United Kingdom
- Volunteers
- 120 people
- Sponsor
- University of Plymouth
Taking Charge of Cognitive Impairment in Patients With Mood Disorders
Evaluation of a Cognitive Remediation Program for Mood Disorders
Psychotherapeutic management of cognitive disorders in patients suffering from a mood disorder
- Trial name
- ECO-DBP (NCT04354974)
- Testing
- Evaluation
- Where
- France
- Volunteers
- 36 people
- Sponsor
- Centre hospitalier de Ville-Evrard, France
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