Clinical trials: Cognitive Manifestations
Attention Deficit Hyperactivity Disorder, Dyslexia
Implementation of Climb Up Program for Children With Attention Deficit Hyperactivity Disorder (ADHD) and Dyslexia in a School in India
A multimodal intervention was rolled out at a large public school in Najibabad, Uttar Pradesh (UP). The program identified elementary school children with ADHD and Dyslexia using standard screening of all children who had…
- Trial name
- ClimbUp (NCT01012778)
- Testing
- Climb Up ADHD and Dyslexia Program
- Where
- India
- Volunteers
- 76 people
- Sponsor
- Climb Up Kids
Postoperative Delirium
Clinical Trial With Quetiapine Prophylaxis Postoperative Delirium in High Risk Surgical Patients
Double blinded Clinical trial to test efficacy of Quetiapine versus placebo in reducing postoperative delirium in high risk surgical patients after three days of treatment.
- Trial name
- NCT03739476
- Testing
- Quetiapine 25 milligrams capsule
- Where
- Spain
- Volunteers
- 54 people
- Sponsor
- Fundación Instituto de Estudios de Ciencias de la Salud de Castilla y León
Rare Disorders, Undiagnosed Disorders
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
The Coordination of Rare Diseases at Sanford (CoRDS) is an international patient registry that serves as a centralized resource for rare disease research.
- Conditions
- Rare Disorders, Undiagnosed Disorders, Disorders of Unknown Prevalence, Cornelia De Lange Syndrome
- Trial name
- CoRDS (NCT01793168)
- Where
- United States
- Volunteers
- 20,000 people
- Sponsor
- Sanford Health
Low Flow Anesthesia, Sevoflurane
Low Flow Anesthesia in Children Undergoing Strabismus Surgery
Emergence agitation (EA) involves restlessness, disorientation, excitation, non-purposeful movement, inconsolability, thrashing, and incoherence during early recovery from general anesthesia.
- Conditions
- Low Flow Anesthesia, Sevoflurane, Strabismus, Emergence Delirium
- Trial name
- LFA in child (NCT06560268)
- Testing
- Sevoflurane; In our study, the effects of sevoflurane in different FGFs administered in children undergoing strabismus surgery on EA and anesthetic agent consumption will be investigated.
- Volunteers
- 150 people
- Sponsor
- Cukurova University
Primary Progressive Aphasia
Preventing Language Decline in Dementia
This study will establish factors fundamental to the improvement in communication and quality of life for people with dementia known as primary progressive aphasia (PPA).
- Trial name
- NCT02541097
- Testing
- Language therapy
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Baycrest
Pain, Constipation
Effect of Lidocaine and Esmolol to Improve the Quality of Recovery
The purpose of this prospective, randomized, double-blinded, active-controlled study is: To assess the effectiveness of systemic administration of lidocaine and esmolol in combination (vs.
- Conditions
- Pain, Constipation, Nausea, Vomiting
- Trial name
- NCT01114997
- Testing
- Lidocaine, Esmolol, Lidocaine + Esmolol (Combo)
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Cedars-Sinai Medical Center
Fibromyalgia
A Study of Digital Cognitive Behavioural Therapy for Insomnia in Fibromyalgia
The goal of this clinical trial is to investigate the potential benefits of a digital Cognitive Behavioural Therapy for Insomnia (dCBT-I) platform, Sleepio, in individuals suffering from fibromyalgia, a condition commonly…
- Trial name
- Pain-LESS (NCT05962138)
- Testing
- Digital Cognitive Behavioural Therapy for Insomnia
- Where
- United Kingdom
- Volunteers
- 80 people
- Sponsor
- University of Oxford
Femoral Neck Fracture
Fascia Iliaca Block in the Emergency Department for Analgesia After Femoral Neck Fracture
Femoral neck fracture is very common in the elderly and can produce severe to moderate pain. As this pathology is not life-threatening, waiting time in the emergency department may be prolonged due to the high number of…
- Trial name
- NCT02433548
- Testing
- Fascia iliaca block
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Obesity, Morbid, Surgery
Multimodal Analgesia Effect on Post Surgical Patient
Patients undergoing Bariatric Surgery at the University of California Davis Medical Center will be divided into two groups, one receiving Standard of Care pain control medications vs the second group which will receive…
- Conditions
- Obesity, Morbid, Surgery, Bariatric Surgery Candidate
- Trial name
- NCT04240626
- Testing
- Neurontin, Dilaudid Injectable Product, Marcaine Injectable Product
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of California, Davis
Pain Management
Regional Anesthesia to Reduce Opioid Use Following Functional Endoscopic Sinus Surgery
Opioids are prescribed for moderate to severe pain disorders; however, there are contraindications and side effects that are common to all opioids.
- Trial name
- NCT03757715
- Testing
- Bupivacaine, Dexamethasone
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- University of Alabama at Birmingham
Cancer
Impact of Therapeutic Osteopathy-hypnosis on Cancer Patients.
Osteopathy is recognized as a beneficial complementary approach for cancer patients. By addressing tissue mobility, circulation, and muscle tension, it helps improve physical comfort, reduce musculoskeletal pain, and foster…
- Trial name
- HYPOSTEO (NCT07860476)
- Testing
- Osteopathy, Hypnosis
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Institut Rafael
Transient Global Amnesia
PRevalence Of Transient Global Amnesia in Obstructive Sleep Apnea Syndrome
Amnesic stroke is an amnestic syndrome lasting less than 24 hours characterized by the occurrence of anterograde amnesia often associated with retrograde amnesia, the pathophysiology of which is still poorly understood at…
- Trial name
- PROTOS (NCT06903026)
- Where
- France
- Volunteers
- 250 people
- Sponsor
- University Hospital, Strasbourg, France
Colonoscopy, Sedation and Analgesia
The Effectiveness of Sedation and Analgesia in Colonoscopy Treatment of Colorectal Polyps
This study aims to evaluate the effectiveness of sedation and analgesia in the treament of colorectal polyps by colonoscopy.
- Trial name
- NCT04906317
- Testing
- midazolam and dezocine, Propofol
- Where
- China
- Volunteers
- 340 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Pain Management, Arthroplasty
Effect of Preoperative Pain Education on Anxiety, Pain, and Analgesic Use in Total Knee and Hip Replacement Patients
This randomized controlled trial evaluates whether a standardized preoperative pain education session delivered by a nurse reduces postoperative pain intensity and surgical anxiety among adult elective orthopedic surgery patients…
- Conditions
- Pain Management, Arthroplasty, Knee Replacement, Hip Replacement
- Trial name
- Pain-Anxiety (NCT07362589)
- Testing
- Pain education
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Yeditepe University
Delirium, Awakening, Post-Anesthesia Delayed
Validation and Reliability of the Turkish 4AT Scale for Post-Anesthesia Awakening Delirium
Background: Delirium is a common and serious condition in hospitalized patients that often leads to extended hospital stays and increased healthcare costs. Accurate and timely detection is essential for optimal patient outcome.
- Conditions
- Delirium, Awakening, Post-Anesthesia Delayed, Delirium, Postoperative, Nurse's Role
- Trial name
- NCT06187389
- Testing
- 1 Grups
- Where
- Turkey (Türkiye)
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- Kilis 7 Aralik University
Aphasia, Stroke, Acute
tDCS to Treat Subacute Aphasia
This study proposes to use transcranial direct current stimulation (tDCS), a technique by which a very small electrical current (2 mA) is applied to the scalp, along side speech therapy in patients with subacute stroke and…
- Trial name
- NCT04048668
- Testing
- Transcranial Direct Current Stimulation (tDCS)
- Where
- United States
- Sponsor
- University of Pennsylvania
Cognitive Impairment, Insulin-like Growth Factor 1
IGF-1, Sarcopenia and Mortality: a Cohort Study in Patient With Cognitive Impairment
Insulin-like growth factor 1 (IGF)-1 is an important neuromyotrophic hormone. Disregulation of this hormone has been reported to influence the genesis of cognitive impairment and dementia in the elderly patients.
- Trial name
- ISAAC (NCT02139410)
- Testing
- IGF-1 serum value
- Where
- 2 sites in Italy
- Volunteers
- 589 people
- Sponsor
- University of Roma La Sapienza
Delirium, Pain
Evaluation of Quality Indicators on Analgesia, Sedation and Delirium in Intensive Care Patients and Their Impact on Outcome Indicators and Economic Indicators
Retrospective cohort study to investigate the adherence to the process indicators for pain management, sedation management and management of delirium on outcome indicators and cost/revenues in individual patients and subcohorts.
- Trial name
- NCT05384613
- Where
- Germany
- Volunteers
- 20,220 people
- Sponsor
- Charite University, Berlin, Germany
Depression, Anhedonia
Multimodal Differences in Effort-based Decision-Making in Depression
Major depressive disorder (MDD) is a serious condition that causes long-term symptoms such as feeling sad, losing interest in activities, and having thoughts of self-harm.
- Trial name
- BBQS (NCT06648460)
- Testing
- Effort-based Decision-Making Task
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Georgia Institute of Technology
Transient Global Amnesia (TGA)
Neuropsycholgy and Neuroimaging in Transient Global Amnesia
The purpose of this study is to establish a diagnosis in transient global amnesia (TGA) in assessing three episodic memory's abilities (mental simulation throught the future, and the past, the learning of personnal actions i-e…
- Trial name
- 2NIA (NCT02562560)
- Testing
- Neuropsychological tests, Cerebral imaging (MRI, PET-FDG)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen