Clinical trials: Cognitive Performance in Healthy Adults
Older Adults, Age Problem
Influence and Relationships Between Square-stepping Exercise and Brain Activation, Cognitive Function, Physical Performance in Healthy Older Adults
Background and purposes: Square-stepping exercise (SSE) has been proved to be an effective intervention for motor and cognitive function in older adults. However, the underlying mechanism of SSE still remains undetermined.
- Trial name
- NCT05891574
- Where
- Taiwan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University
Cognitive Function, Mood
The Effects of Efalex Active 50+ on Cognitive Performance, Well-being and Cerebral Hemodynamics in Healthy Older Adults
Dietary intake of omega-3 polyunsaturated fatty acids (n-3 PUFAs) is inversely associated with cognitive decline and dementia (e.g. Kalmijn et al. 2004, Heude et al. 2003, Morris et al. 2005, Dullemeijer et al. 2009).
- Conditions
- Cognitive Function, Mood, Well-being, Cerebral Blood Flow
- Trial name
- NCT01185379
- Testing
- Efalex active 50+, DHA rich fish oil
- Where
- United Kingdom
- Volunteers
- 261 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Healthy, Young Adults
Remote Limb Ischemic Conditioning to Enhance Learning and Muscle Strength in Healthy Young Adults
The purpose of this research study is to determine if remote limb ischemic conditioning (RLIC) can enhance learning of a motor (balance) and an ecologically valid, complex cognitive-motor (driving) task, and increase skeletal…
- Trial name
- NCT03512028
- Testing
- RLIC, Muscle strength training, Driving training
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Stress Response, Mental Stress
Cranberry Polyphenols and Stress Resilience During Multitasking in Healthy Adults
This randomized, double-blind, placebo-controlled clinical trial evaluates whether 70 days of daily cranberry juice consumption improves cognitive performance and motor accuracy and reduces psychological and physiological stress…
- Conditions
- Stress Response, Mental Stress, Multitasking Behavior and Multitasking Ability, Physiological Stress
- Trial name
- CRAN-MULTI (NCT07453537)
- Testing
- Cranberry juice
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of Florida
Healthy Adult Male
Effects of Caffeine on Agility in Amateur Soccer Players
This randomized, double-blind, placebo-controlled crossover clinical trial aims to investigate the acute effects of caffeine supplementation on motor and perceptual-cognitive components of agility performance in male amateur…
- Trial name
- NCT07844122
- Testing
- Caffeine 300 MG
- Where
- Slovakia
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Comenius University
Dehydration, Rehydration
Clinical Trial to Evaluate the Effects of Two Novel Hydration Beverage Formulas on Rehydration in Healthy Adults
Dehydration lowers both physical and mental performance if it is severe enough. Performance declines are more pronounced in hot conditions or after prolonged strenuous activity such as exercise.
- Conditions
- Dehydration, Rehydration, Exercise Performance, Exercise Recovery
- Trial name
- NCT05428761
- Testing
- TP1, TP2
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Liquid I.V.
Healthy Aging
Dual-task Training in Older Adults
This study seeks to understand what factors influence the capacity to perform simultaneous motor and cognitive tasks in older adults to improve movement throughout their community with the least risk of injury.
- Trial name
- NCT05296551
- Testing
- Motor Task, Cognitive-motor dual-task
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- George Washington University
Nutrition, Cognitive Change
Effect of Morning Snack on Cognitive Performance in Adults
To characterize the effects of three chocolate snacks on cognitive performance, subjective appetite, food intake control, and glycemic response in normal weight adults.
- Conditions
- Nutrition, Cognitive Change, Food Intake Control, Satiety
- Trial name
- NCT03637829
- Testing
- Control, White chocolate, Dark chocolate 1
- Where
- Canada
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Toronto Metropolitan University
Healthy
Movement-Sequence Observation in Healthy Adults: Motor and Cognitive Effects on Effector-Independent Performance
Studies examining the effects of action observation (AO) on ipsilateral versus contralateral upper limb (UL) motor performance have reported mixed findings.
- Trial name
- NCT07531212
- Testing
- Action observation (AO), Sequence observation (SO), Nature Observation (NO)
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ariel University
Cognitive Assessment, Cognition
Effects of Transcutaneous Auricular Vagus Nerve Stimulation on Cognitive Performance and Sex Differences
This study investigates the effects of transcutaneous auricular vagus nerve stimulation (taVNS) on cognitive performance in healthy adults.
- Conditions
- Cognitive Assessment, Cognition, taVNS, Vagus Nerve Stimulation
- Trial name
- NCT07256080
- Testing
- Active taVNS
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Bahçeşehir University
Dehydration, Rehydration
Clinical Study to Evaluate the Effects of Two Novel Hydration Beverage Formulas on Rehydration in Healthy Adults
The aim of the clinical trial is to evaluate the efficacy of two novel hydration products on rehydration following exercise.
- Conditions
- Dehydration, Rehydration, Exercise Performance, Exercise Recovery
- Trial name
- NCT05428228
- Testing
- TP1, TP2
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Liquid I.V.
Healthy Older Adults, Postural Balance
INDIVIDUALIZED DUAL-TASK TRAINING FOR BALANCE AND MOBILITY IN OLDER ADULTS
The goal of this clinical trial is to prevent functional decline and improve mobility in healthy older adults aged 65 and over. The main questions it aims to answer are: What is the effect of individualized dual-task training on…
- Conditions
- Healthy Older Adults, Postural Balance, Dual Task Exercises in Elderly People, Dual Task Cost
- Trial name
- NCT07448961
- Testing
- Individualized Dual-Task Training, Standardized Dual-Task Training, Single-Task Motor Training
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Sezen Karaborklu Argut
Healthy Adult Male and Female Volunteers
Neurocognitive Effects of Extended-Release Methylphenidate in Healthy Adults
This study evaluated the effects of methylphenidate (MPH), a stimulant medication commonly used to treat attention deficit hyperactivity disorder (ADHD), in healthy adults without ADHD.
- Trial name
- NCT07742631
- Testing
- Methylphenidate Stimulant medication therapy
- Where
- South Africa
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Witwatersrand, South Africa
Cognitive Change, Motor Activity
The Influence of Gender on Dual Task Performance in Young Healthy Adults
Dual tasking (DT), or the act of conducting multiple, simultaneous tasks, is wide spread in daily life .In particular, the vast majority of mobility tasks we complete (e.g., standing, walking, stepping, etc.) occur while…
- Trial name
- NCT05912530
- Testing
- no intervention
- Where
- Saudi Arabia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Jouf University
Healthy Older Adults, Memory Complaints
A Computer-based Memory Strategy Training Program for Older Adults
A computer-based cognitive rehabilitation program based on daily tasks utilising the semantic or perceptual encoding strategies called Enhancing Memory in Daily Life (E-MinD Life) has been developed for Chinese people.
- Conditions
- Healthy Older Adults, Memory Complaints, Mild Cognitive Impairment (MCI)
- Trial name
- NCT07039708
- Testing
- E-MinD Life Semantic, Cognitive stimulation
- Where
- Hong Kong
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Cognitive Performance
Effects of Time of Day and Nut Intake on Cognitive Performance
This is a 2 x 2-factor crossover design study to investigate the effects of time of day and nuts on post-meal cognitive performance.
- Trial name
- NCT06343142
- Testing
- Nuts, Nut-free meal
- Where
- Australia
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Monash University
Healthy Participants
The Effect of α-GPC on Cognitive Function and Sports Performance
The goal of this clinical trial is to find out whether daily supplementation with Alpha-Glycerophosphocholine (α-GPC) can improve cognitive function and sports performance in healthy adults.
- Trial name
- NCT07267845
- Testing
- Alpha-Glycerophosphocholine（α-GPC）
- Where
- Ireland
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Nanjing Nutrabuilding Bio-tech Co., Ltd.
Healthy Volunteers
Validity of an Online Neurocognitive Test Battery, the Brain Performance Test (BPT), in Normal Healthy Adults
The purpose of this study is to evaluate the concurrent validity between the Brain Performance Test (BPT) subtests and corresponding conventional in-person neuropsychological assessments (NP).
- Trial name
- NCT02518204
- Testing
- BPT, NP
- Where
- 3 sites in United States
- Volunteers
- 229 people, healthy volunteers welcome
- Sponsor
- Lumos Labs, Inc.
Mental Acuity
Effects of Red Panax Ginseng Supplementation on Cognitive Performance and Emotional Well-Being in Young Healthy Adults
College students face substantial and persistent mental health challenges that directly affect cognitive performance, stress regulation, and emotional well-being.
- Trial name
- NCT07648316
- Testing
- Ginseng
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Elderly Adults, Mild Cognitive Impairment
Agility Training and Its Relations in Elderly Adults With and Without MCI
The following three-part proposal will focus on the effects of agility training as well as the relationship between agility ability and motor and cognitive function, and risk of falls in elderly adults with or without mild…
- Conditions
- Elderly Adults, Mild Cognitive Impairment, Healthy
- Trial name
- NCT05537363
- Testing
- Health education, Multicomponent training, Agility training
- Where
- Taiwan
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital