Clinical trials: Cognitive Performance in Healthy Adults
Cognition, Cognitive Performance
A Clinical Trial to Investigate the Safety and Efficacy of AP-Brain on Cognitive Performance at Varying Dosages in Healthy Middle-aged and Older Adults With Self-reported Memory Problems
The goal of this clinical trial is to investigate the safety and efficacy of AP-Brain on cognitive performance at varying dosages in healthy middle-aged and older adults with self-reported memory problems.
- Trial name
- NCT07388043
- Testing
- AP-Brain (1g), AP-Brain (3g), AP-Brain (5g)
- Where
- 2 sites in Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Rousselot BVBA
Frailty, Sarcopenia
Comprehensive Geriatric Assessment in Adults Aged 40 Years and Older Living With HIV
People living with HIV are experiencing longer life expectancy due to effective antiretroviral therapy; however, they may develop age-related conditions earlier than the general population.
- Trial name
- HIV-AGE40 (NCT07453303)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital
Cognitive Function, Memory
The Memory and Cognitive Performance Study
The primary purpose of this study is to evaluate the impact of a novel, neuro-protective and neuro-restorative dietary supplement (Braini®) on standardized memory and cognitive performance parameters.
- Conditions
- Cognitive Function, Memory, Brain Health
- Trial name
- NCT04025255
- Testing
- Braini
- Where
- United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Vita Naturel, LLC
Healthy Volunteers
Short-Term Rhodiola Rosea for Anaerobic Performance and Cognitive Function in Resistance-Trained Adults
This study will evaluate whether 7 days of Rhodiola rosea (golden root) supplementation can improve resistance-exercise performance and cognitive function in resistance-trained men and women.
- Trial name
- NCT07225413
- Testing
- Rhodiola rosea (low dose), Rhodiola rosea (high dose)
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Jacksonville State University
Mild Cognitive Impairment, Mild Dementia
Computer-based Cognitive Rehabilitation Program for Healthy Older Adults, Older People With Mild Cognitive Impairment and Mild Dementia
This study will adopt a newly developed computer-based cognitive rehabilitation program targeting the encoding stage of memory. The aims of the study are: 1.
- Conditions
- Mild Cognitive Impairment, Mild Dementia, Healthy Older Adults
- Trial name
- NCT03430401
- Testing
- Perceptual-based memory encoding, Semantic-based memory encoding, Cognitive stimulation
- Where
- Australia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Western Sydney
Cognitive Change, Mood
The Effects of Resveratrol Supplementation on Inflammation and Cognitive Performance in Healthy Adults
Previous research has suggested that high levels of systemic inflammation can contribute to cognitive deficits and additional health problems; consumption of polyphenols have been shown to have an anti-inflammatory effect.
- Conditions
- Cognitive Change, Mood, Systemic Inflammation
- Trial name
- NCT04314739
- Testing
- Resveratrol
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Exercise Environment and Cognitive Performance in Older Adults
Outdoor vs. Indoor Exercises and Cognitive Functions in Older Adults
This observational, cross-sectional study aims to comparatively investigate the effects of outdoor versus indoor exercise environments on overall cognitive performance and its specific sub-domains (attention, memory, and…
- Trial name
- NCT07728786
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Muğla Sıtkı Koçman University
Sleep
Evaluation of SmartSleep Technology for Improving the Efficiency and Restorative Quality of Sleep in Healthy Adults
This study aims to assess whether slow wave sleep enhancement using SmartSleep technology benefits daytime cognitive performance during periods of chronic sleep restriction.
- Trial name
- NCT03911154
- Testing
- Philips SmartSleep Technology--Continuous Fixed Interval modality, Philips SmartSleep Technology--Block modality, Philips SmartSleep Technology--In-Phase Adjustable modality
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Cognitive Performance in Healthy Adults
Back Massage Before a Cognitive Task in Healthy Young Adults
This study will compare a 15-minute back massage, 15 minutes of quiet rest, and no additional break before a mental task in healthy adults aged 18 to 27 years.
- Trial name
- NCT07893886
- Testing
- Classical Back Massage, Passive Rest, No Additional Break
- Where
- Poland
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- DSW Ideis University
Cognitive Change
Cognitive and Cerebral Blood Flow Effects of Zanthozylum Armatum Fruit Extract in Healthy Adults Aged 30 - 55
Zanthozylum armatum (Z. armatum)-otherwise known as Nepalese pepper, or timut-is an perennial shrub found in India and across Southeast Asia. Preparations of the bark, fruit and seeds of Z.
- Trial name
- NCT03673930
- Testing
- Zanthozylum armatum
- Where
- United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Hypoxia
Effects of Hypoxia on Cognitive Performance
The goal of this clinical trial is to determine the effects of different hypoxia exposures (FiO2 = 11%, 13%, 15%, and 21%) on cognitive performance in healthy adults.
- Trial name
- HYPCOG (NCT06318312)
- Testing
- Hypoxia
- Where
- Spain
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Castilla-La Mancha
Cognitive Function
Investigation of Acute Mood and Cognitive Performance Effects of Beverages Containing Phenolics in Healthy Adults
An acute, randomized, placebo controlled, double blinded crossover study in health subjects. Participants will complete 4 intervention arms in random order consisting of a placebo control beverage, a high dose phenolic beverage…
- Trial name
- NCT02675621
- Testing
- Phenolic Beverage
- Where
- United Kingdom
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Healthy
Pre-Workout on Exercise Performance and Cognition
The purpose of this study is to determine the effects of four different pre-workout beverages as compared to placebo on muscular strength and endurance, perceived energy and cognitive performance in healthy adult males.
- Trial name
- NCT02255201
- Testing
- Master Performance Blend Dose 1, Master Performance Blend Dose 2, Performance Energy Blend
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Miami Research Associates
Healthy Aging
Effects of Astaxanthin Supplementation on Metabolism, Cognition, and Physical Function in Older Adults
This study evaluated whether astaxanthin supplementation affects the body's ability to use fat for energy, cognitive performance, and physical function in healthy older adults.
- Trial name
- NCT07876193
- Testing
- Astaxanthin Oral Capsule
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of North Alabama
Healthy
Mediterranean Diet Interventions for Eating Behavior and Cognitive Performance Among Older Adults in the Community
The object is to investigate the effects of a modified Mediterranean diet learning intervention program with a Mini-flipped game strategy on dietary behavior and cognitive function of elderly people in the community.
- Trial name
- NCT04788446
- Testing
- Mini-flipped Game-based Learning, Balanced diet
- Where
- Taiwan
- Volunteers
- 84 people
- Sponsor
- National Yang Ming Chiao Tung University
Neurodegeneration
Effects of Flavonoids on Cognitive Performance in Healthy Young Adults
The purpose of this study is to investigate changes in cerebral blood flow, blood flavonoid levels, brain-derived neurotrophic factor, vascular reactivity and cognitive performance in young adults as a result of acute…
- Trial name
- NCT01312597
- Testing
- Fruit juice beverage
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Reading
Aging
Non-invasive Nerve Stimulation and Cognitive Training to Improve Cognitive Performance in Healthy Older Adults
Decline in brain health and associated loss of cognitive function in healthy aging decreases quality of life.We need better tools to both enhance brain health and improve cognitive performance in healthy brain aging so that it…
- Trial name
- NCT04276805
- Testing
- Transcutaneous vagal nerve stimulation (tVNS), Cognitive training
- Where
- 2 sites in United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Florida
Brain Health, Longevity
L-serine and Strength Training in the Elderly
This study investigates whether taking the amino acid L-serine, either alone or in combination with targeted strength training, can have a positive effect on mental performance, brain function, and physical fitness in older…
- Conditions
- Brain Health, Longevity, Cognitive Performance, Strength Training Effects
- Trial name
- AAAging (NCT07466290)
- Testing
- Strength training, L-serine supplementation, Control (cornstarch)
- Where
- Austria
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- University of Vienna
Healthy, Brain Stimulation
Effects of Transcranial Electrical Stimulation on Task Performance in Healthy Adults
The objective of this randomized, double-blind, sham-controlled, crossover study is to evaluate the effects of transcranial electrical stimulation (tES) on complex cognitive task performance in healthy adult volunteers.
- Conditions
- Healthy, Brain Stimulation, Transcranial Direct Current Stimulation (tDCS), Cognition
- Trial name
- BRAIN-STIM (NCT06995560)
- Testing
- Active Transcranial Electrical Stimulation
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Healthy Adults; Cognitive Performance; Sleep Quality; Neuromuscular Function
Sex-Divergent Effects of Magnesium L-Threonate Supplementation on Sleep Quality, Cognitive Performance, and Neuromuscular Function in Healthy Adults
This study examined the effects of six weeks of magnesium L-threonate (MgT) supplementation on sleep quality, cognitive performance under experimentally induced mental fatigue, neuromuscular function, and psychophysiological…
- Trial name
- NCT07706283
- Testing
- Magnesium L-threonate
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Barry University