Clinical trials: Cognitive Remediation
Anorexia Nervosa
Shifting Perspectives: Enhancing Outcomes in Anorexia Nervosa With CRT
Anorexia Nervosa is a serious life-threatening illness with a typical age of onset in adolescence; if not effectively treated, it has the potential to significantly impact adolescent development and quality of life.
- Trial name
- NCT03928028
- Testing
- Cognitive Remediation Therapy, Family Based Treatment
- Where
- United States
- Volunteers
- 177 people
- Sponsor
- Children's Hospital of Philadelphia
Bipolar Disorder, Bipolar and Related Disorders
Targeted Alternating Current and Cognitive Training Intervention for Cognitive Control in Bipolar Disorders
This study is testing whether a type of gentle brain stimulation, combined with computer-based brain training exercises, can help improve thinking skills in Veterans with bipolar disorder.
- Conditions
- Bipolar Disorder, Bipolar and Related Disorders, Veterans, Suicide
- Trial name
- TACTIC-BD (NCT07845409)
- Testing
- Soterix 1x1 tES mini-CT
- Where
- United States
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Post COVID-19 Condition
Multidisciplinary Day-hospital Versus Waiting List Management of Post-COVID-19 Persistent Symptoms (ECHAP-COVID)
After an acute episode of COVID-19, many patients experience persistent or recurrent symptoms with substantial impairment of their quality of life.
- Trial name
- ECHAP-COVID (NCT05532904)
- Testing
- Personalized multidisciplinary day-hospital intervention
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Alzheimer's Disease
Computer-Based Training for Mild Alzheimer's Disease
The primary objective of this study is to evaluate the effects of computer-based training program ("HiFi-AD") on the memory and cognitive abilities of individuals diagnosed with mild Alzheimer's Disease (AD).
- Trial name
- NCT00319891
- Testing
- Computer-based Cognitive Training
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Posit Science Corporation
Schizophrenia
Computer Assisted Cognitive Remediation Program in Schizophrenia
The purpose of this study is to determine whether computer-assisted cognitive remediation therapy is effective in the treatment of cognitive deficits in schizophrenia.
- Trial name
- CACREPS (NCT01598220)
- Testing
- Computer-assisted cognitive remediation therapy, attentional task
- Where
- Spain
- Volunteers
- 135 people
- Sponsor
- Gemma Garrido García
Smoking Cessation
Cognitive Remediation With D-Cycloserine
One hundred seventy-five eligible participants will be enrolled with aim of randomizing 60 to a double-blind, placebo-controlled trial of D-cycloserine added to cue-exposure treatment to prevent relapse to smoking.
- Trial name
- NCT01399866
- Testing
- D-cycloserine
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
ADHD
Combined Cognitive Remediation and Behavioral Intervention for Treatment of Attention-deficit/Hyperactivity Disorder (ADHD)
The objective of this study is to evaluate a novel sequenced combination of a promising, computerized cognitive training program targeting working memory (WM) deficits in children with attention-deficit/hyperactivity disorder…
- Trial name
- NCT01137318
- Testing
- Cognitive remediation and Parent Training
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- Queens College, The City University of New York
Schizophrenia
Specific Cognitive Remediation for Schizophrenia
Rationale: Cognitive deficits are a core feature in schizophrenia. Conventional treatments (antipsychotic medication and psychological treatments) have limited effects so cognitive remediation programs were designed to alleviate…
- Trial name
- RECOS (NCT01607424)
- Testing
- cognitive remediation
- Volunteers
- 151 people
- Sponsor
- Hôpital le Vinatier
Schizophrenia, Schizophreniform Disorders
Individual Placement and Support and/or Cognitive Remediation Therapy Added to TAU in Patients With Early Schizophrenia
This study aims to test the hypothesis that addition of Individual Placement and Support (IPS) and/or Cognitive Remediation Therapy (CRT) in addition to treatment as usual in patients with early psychosis will be feasible and…
- Conditions
- Schizophrenia, Schizophreniform Disorders, Schizoaffective Disorder, Psychosis
- Trial name
- NCT03974620
- Testing
- Individual Placement and Support, Cognitive Remediation Therapy
- Volunteers
- 120 people
- Sponsor
- Pakistan Institute of Living and Learning
ADHD-add
MEthylphenidate in ADHD - Addiction(s) Comorbidity: Value of Adding a Cognitive Remediation Program to Improve Short- and Medium-term Therapeutic Response
MEthylphenidate in ADHD - Addiction(s) comorbidity: benefit of adding a cognitive remediation program to improve short- and medium-term therapeutic response
- Trial name
- META (NCT06906328)
- Testing
- Cognitive remediation program, with the PRESCO® software, Control program, with the AUDITICO® software
- Where
- 6 sites in France
- Volunteers
- 248 people
- Sponsor
- Nantes University Hospital
Cognitive Impairment, Psychosis
Action-based Cognitive Remediation for First Episode Psychosis
Cognitive impairments are a core and enduring feature of first-episode psychosis and schizophrenia, and are associated with significant functional impairment.
- Trial name
- NCT03814122
- Testing
- Action-based cognitive remediation, Waitlist Control Group
- Where
- Canada
- Volunteers
- 13 people
- Sponsor
- University of Manitoba
Alcohol Use Disorder, Mild Cognitive Impairment
The Combination of Donepezil and Cognitive Training for Treating Alcohol Use Disorder
This is an open label feasibility trial to learn whether the combination of donepezil and cognitive remediation therapy (Donepezil + CRT) may improve neurocognitive functioning and decreasing alcohol use in Veterans with alcohol…
- Trial name
- NCT04318639
- Testing
- Donepazil
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- VA Connecticut Healthcare System
Velocardiofacial Syndrome
Computerized Cognitive Skills Training for Adolescents With Velocardiofacial Syndrome
This study will test a computer-based treatment for youth with the genetic disorder velocardiofacial syndrome (VCFS) to help them improve skills in memory, attention, and executive functioning.
- Trial name
- NCT00917189
- Testing
- Challenging Our Minds Program
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- State University of New York - Upstate Medical University
Schizophrenia
Functional Neuroimaging Effects of Cognitive Remediation Training
The purpose of this study is to examine behavioral and functional brain changes occuring as a result of cognitive remediation training in patients with schizophrenia.
- Trial name
- NCT00481156
- Testing
- Cognitive Remediation, Cognitive Behavioral Social Skills Training, Retest in Health Controls
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Cancer, Cognitive Impairment
Digital Intervention Targeting Cancer-related Cognitive Impairments
Cognitive deficits are frequently reported following cancer treatment and can significantly impact daily functioning. These cognitive impairments often persist for years after cancer treatment.
- Trial name
- NCT06693102
- Testing
- Digital intervention targeting cancer-related cognitive impairments, Crossword and sudoku taks
- Where
- Norway
- Volunteers
- 60 people
- Sponsor
- Haukeland University Hospital
Major Depression
Remote Cognitive Remediation for Depression
Major depressive disorder is the number one cause of disability worldwide. Evidence regarding the effectiveness of various treatments for patients with severe depression is still lacking.
- Trial name
- RECORD (NCT03492203)
- Testing
- Active Cognitive Remediation, Cognitive Remediation Control, Online computer exercises
- Where
- Canada
- Volunteers
- 75 people
- Sponsor
- Queen's University
Schizophrenia, Schizoaffective Disorder
Cognitive Remediation in Early Phase Psychosis
The purpose of the study is to investigate the effect of a 30 hour cognitive remediation program for young patients with early phase schizophrenia spectrum disorders on cognitive, clinical and functional outcome measures.
- Conditions
- Schizophrenia, Schizoaffective Disorder, Psychosis NOS
- Trial name
- NCT01546467
- Testing
- Cognitive remediation
- Where
- Norway
- Volunteers
- 50 people
- Sponsor
- Oslo University Hospital
Psychotic Disorders
Cognitive Remediation and Supported Education in Psychotic Disorders
This trial aims to assess the added value of cognitive remediation therapy to supported education intervention in young adults with a psychotic disorder.
- Trial name
- REUSSIR (NCT04040829)
- Testing
- Cognitive remediation therapy (CR), Supported education (SE), Treatment as usual (TAU)
- Where
- 3 sites in Canada
- Volunteers
- 9 people
- Sponsor
- Centre de Recherche de l'Institut Universitaire en Santé Mentale de Québec
Mild Cognitive Impairment, Major Depressive Disorder
Home-Based CR and tDCS to Enhance Cognition in Persons With Mild Cognitive Impairment and Late Life Depression
The overall goals of this project are to assess the feasibility and impact of designing and implementing an at-home intervention aimed at preventing long-term cognitive decline and improving cognition in individuals currently…
- Conditions
- Mild Cognitive Impairment, Major Depressive Disorder, Alzheimer's Dementia, Transcranial Direct Current Stimulation
- Trial name
- NCT02959502
- Testing
- Receive tDCS+CR, Facilitate tDCS + CR
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Centre for Addiction and Mental Health
Brain Tumor
Neuroplasticity-Based Cognitive Remediation for Pediatric Brain Tumor Survivors
This research will leverage novel pilot research conducted by the investigators to take important first steps in addressing neurocognitive late effects by intervening early, during treatment, with a promising computerized…
- Trial name
- CRPBT (NCT02129712)
- Testing
- Cognitive training
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Vanderbilt University