Clinical trials: Cognitive Remediation
Mild Cognitive Impairment
Assessing and Improving the Durability of Compensatory Cognitive Training for Older Veterans
Veterans have numerous risk factors (e.g., Post-traumatic stress disorder (PTSD), traumatic brain injury (TBI), cerebrovascular problems) for later-life cognitive and functional decline.
- Trial name
- AID-CCT (NCT05770479)
- Testing
- Motivationally-Enhanced Compensatory Cognitive Training (ME-CCT) Booster Modules, Treatment As Usual
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- VA Office of Research and Development
Schizophrenia
Cognitive Remediation Method by Rhythmic, Vocal and Embodied Musical Learning for Stabilized Schizophrenic Patients
ARCoS is a pilot study evaluating the feasibility and preliminary effects of a method of cognitive remediation by a Rhythmic, Vocal and Embodied Musical Learning for a population of stabilized schizophrenic patients.
- Trial name
- ARCoS (NCT05124470)
- Testing
- cognitive remediation by musical training sessions
- Where
- 2 sites in France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Toulouse
Glioma, Brain Tumor, Primary
Cognitive Remediation Therapy for Brain Tumor Patients: Improving Working Memory
To investigate a computer-based Cognitive Remediation Therapy (CRT) for brain tumor patients at the Massey Cancer Center on measures of cognitive functioning (e.g., working memory, attention, processing speed, language…
- Trial name
- NCT03323450
- Testing
- CogMed®
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Virginia Commonwealth University
Schizophrenia
Brain Image Markers Associated With Cognitive Training and Aerobic Exercise in Schizophrenia
This study evaluates the brain correlates of Cognitive Training and Aerobic Exercise in schizophrenia. A third of participants will receive Cognitive Training plus Standard Care for schizophrenia.
- Trial name
- CORTEX-SP (NCT03509597)
- Testing
- Aerobic Exercise, Cognitive Training, Treatment as usual
- Where
- Spain
- Volunteers
- 150 people
- Sponsor
- Red Salud Mental Araba
Drug Use Disorders
Targeting Self-regulatory Deficits Through Cognitive Remediation Intervention
We are proposing a small randomized clinical trial in which 100 substance users will complete the existing Psychotherapy Development Center (PDC) pretreatment assessment battery as well as a novel battery of assays to evaluate…
- Trial name
- NCT03373240
- Testing
- TAU plus Cognitive Remediation Program, TAU plus Control Tasks
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Yale University
Bipolar Disorder, Cognitive Impairment
Effect of Action-Based Cognitive Remediation in Patients With Bipolar Disorder
PRETEC-ABC aims to assess the effect of a new form of cognitive remediation, Action-Based Cognitive Remediation (ABCR), in patients with bipolar disorder in remission on cognition, and to assess the neural assays for treatment…
- Trial name
- PRETEC-ABC (NCT03295305)
- Testing
- Action-Based Cognitive Remediation, Unstructured support group
- Where
- Denmark
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital
Mobility Limitation, Motor Activity
Cognitive Remediation to Improve Mobility in Sedentary Seniors
The investigators propose to conduct a single-blind randomized clinical trial to test the efficacy of a computerized cognitive remediation intervention program on improving locomotion in sedentary seniors, a group at an…
- Conditions
- Mobility Limitation, Motor Activity, Difficulty Walking, Cognitive Ability General
- Trial name
- CREM (NCT02567227)
- Testing
- Cognitive Remediation, Active Control
- Where
- United States
- Volunteers
- 383 people, healthy volunteers welcome
- Sponsor
- Albert Einstein College of Medicine
Epilepsy, Traumatic, Brain Injuries, Traumatic
HOme-Based Self-management and COgnitive Training CHanges Lives (HOBSCOTCH) -Post-Traumatic Epilepsy (PTE)
The purpose of this study is to assess the ability of the home-based intervention, HOBSCOTCH-PTE, to improve the quality of life and cognitive function in Service Members, Veterans and civilians with post traumatic epilepsy…
- Trial name
- HOBSCOTCHPTE (NCT05235061)
- Testing
- Home Based Self-management and Cognitive Training Changes lives in post traumatic epilepsy (HOBSCOTCH-PTE), HOBSCOTCH-PTE for Caregivers
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Bipolar Disorder
A Trial of Functional Remediation in Patients With Bipolar Disorder
In the last decade several evidences show that cognitive impairment is a major feature of bipolar disorder (BD), that is strongly associated with patients' functional outcome.
- Trial name
- NCT04577508
- Testing
- Functional Remediation, Treatment as usual
- Where
- Italy
- Volunteers
- 54 people
- Sponsor
- Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
Hoarding Disorder, Attentional Impairment
Cognitive Remediation for Neuropsychological Impairment in Compulsive Hoarding
The primary aim of this pilot randomized controlled trial is to examine whether cognitive remediation, compared to a placebo, improves attention and related cognitive functions in patients with compulsive hoarding.
- Trial name
- NCT01451697
- Testing
- Cognitive Remediation
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Hartford Hospital
Cognitive Remediation, Breast Cancer
Remediation for Mild Cognitive Deficits After Cancer
Cancer survival rates have improved significantly over the past decades and patients now experience a number of side effects including cancer-related cognitive impairment (CRCI): problems with memory, executive function…
- Trial name
- EURECA (NCT04808674)
- Testing
- Cognitive remediation program
- Where
- 2 sites in France
- Volunteers
- 24 people
- Sponsor
- Hospices Civils de Lyon
Schizophrenia
Cerebral Impact of Cognitive Remediation for People Suffering From Schizophrenia
Neurocognitive deficits are frequent with people suffering from schizophrenia. Unlike positive symptoms, cognitive deficits are not reduced with antipsychotic medication.
- Trial name
- IMPACTRCS (NCT04033978)
- Testing
- Cognitive remediation, psychosocial rehabilitation
- Where
- France
- Volunteers
- 78 people
- Sponsor
- Hôpital le Vinatier
HIV-associated Neurocognitive Dysfunction
Cognitive Remediation for HIV-associated Neurocognitive Dysfunction
This study is a validation study to document the acceptability of the revised Plasticity-based Adaptive Cognitive Remediation (PACR) program to patients with HIV-associated Neurocognitive Dysfunction (HAND).
- Trial name
- HAND (NCT02671526)
- Testing
- Computerized plasticity-based adaptive cognitive training
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Posit Science Corporation
Schizophrenia
Cognitive Remediation for Schizophrenia
The purpose of this study is to evaluate the efficacy of an innovative, computer driven cognitive rehabilitation program for individuals with schizophrenia and related disorders.
- Trial name
- NCT00295048
- Testing
- Computer Assisted Cognitive Remediation (CACR)
- Where
- 3 sites in United States
- Volunteers
- 50 people
- Sponsor
- University of Maryland, Baltimore
Schizophrenia Disorders
Cognitive Remediation Method Using Rhythmic, Vocal and Corporal Musical Learning for Schizophrenia
Schizophrenia, affecting 1% of the population, is a persistent disorder characterized by varied symptoms. Antipsychotic medications effectively address positive symptoms (delusions, hallucinations) and relapse but have limited…
- Trial name
- ARCoS-2 (NCT07055204)
- Testing
- "Diapason & Metronome" musical learning
- Where
- 6 sites in France
- Volunteers
- 120 people
- Sponsor
- University Hospital, Toulouse
Depression, Depressive Disorder
Study the Efficacy and Safety of the INtegral Cognitive REMediation Program (INCREM) for Depression
Feeling sad about negative or stressful events has nothing to do with the diagnosis of depression, as this is a very prevalent mental illness among the population with devastating consequences for the person suffering from it.
- Trial name
- INCREM (NCT06590025)
- Testing
- INtegral Cognitive REMediation program, Psychoeducation for depression
- Where
- Spain
- Volunteers
- 296 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Schizophrenia, Bipolar Disorder
Cognitive Training to Improve Work Outcomes in Severe Mental Illness
This study will compare the efficacy of two types of supportive treatments for a program called Individual Placement and Support, which helps people with severe mental illnesses find and keep jobs.
- Conditions
- Schizophrenia, Bipolar Disorder, Depression
- Trial name
- NCT00895258
- Testing
- Individual placement and support plus cognitive training (IPS-CT), Individual placement and support plus enhanced support (IPS-ES)
- Where
- United States
- Volunteers
- 163 people
- Sponsor
- University of California, San Diego
Bipolar Disorder
The Effects of Cognitive Remediation on Cognitive Function in Remitted Bipolar Disorder - a Proof of Concept Study
Cognitive remediation (CR) is a new psychological treatment, which aims to improve cognitive function and coping skills. Several studies have recently demonstrated that CR improves cognitive and occupational function in patients…
- Trial name
- REMEDI (NCT01457235)
- Testing
- Cognitive Remediation
- Where
- Denmark
- Volunteers
- 46 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Schizophrenia, Schizoaffective Disorder
Efficacy of Personalizing Cognitive Remediation for Schizophrenia by Targeting Impairments in Early Auditory Processing
The primary aim of this study is to provide confirmation that Cognitive Remediation (CR) for schizophrenia, when personalized based on pre-treatment assessment of early auditory processing ability, facilitates improved cognitive…
- Trial name
- NCT04554121
- Testing
- Brain Basics, Brain Training
- Where
- 9 sites in United States
- Volunteers
- 194 people
- Sponsor
- Columbia University
Tobacco Use Disorder
Increasing Smoking Cessation Success Through Sleep-amplified Memory Consolidation
The goal of this subproject is to examine the hypothesized improvement of treatment with chess-based training and sleep enhancement, both together and on their own, in smokers.
- Trial name
- NCT05726045
- Testing
- Standard smoking cessation program (SCP), Cognitive remediation treatment (CRT), High-intensity interval training (HIIT evening)
- Where
- Germany
- Volunteers
- 140 people
- Sponsor
- Central Institute of Mental Health, Mannheim