Clinical trials: Cognitive Remediation Therapy
Psychosis, Alcohol Use Disorder
Effects of Action-Based Cognitive Remediation on Substance Misuse in Early Phase Psychosis
Psychotic disorders impact 4.6 people per 1000 globally, with approximately 1.5 million Canadians affected. The age of onset for psychotic disorders often begin during the critical years of youth and early adulthood, resulting in…
- Conditions
- Psychosis, Alcohol Use Disorder, Cannabis Use Disorder
- Trial name
- NCT07056894
- Testing
- Action-Based Cognitive Remediation
- Where
- 2 sites in Canada
- Volunteers
- 50 people
- Sponsor
- Nova Scotia Health Authority
Multiple Sclerosis, Cognitive Deficits
Computerized Exercise Training for Cognitive Remediation in Adults With Multiple Sclerosis Treated With Gilenya
This study is investigating the efficacy of computer-based cognitive exercises as a means of cognitive remediation in patients with Multiple Sclerosis (MS) who are beginning the disease modifying pharmacotherapy Gileyna.
- Conditions
- Multiple Sclerosis, Cognitive Deficits, Gilenya Modifying Therapy for MS
- Trial name
- NCT02141022
- Testing
- plasticity-based computerized cognitive remediation program, Gileyna
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Stony Brook University
HIV/AIDS, Aging
Psychosocial Intervention for Older HIV+ Adults With HAND
CTNPT 029 will test the feasibility and acceptability of cognitive remediation group therapy in older adults living with HIV who have been diagnosed with HIV-associated neurocognitive disorder (HAND).
- Conditions
- HIV/AIDS, Aging, Mild Cognitive Impairment, Group, Peer
- Trial name
- IN-HAND (NCT03483740)
- Testing
- CRGT, HIV group therapy
- Where
- 3 sites in Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Post-traumatic Stress Disorder, Cognitive Dysfunction
The Effectiveness of a Cognitive Training Program, Goal Management Training, on Reducing Cognitive Difficulties and Improving Every-day Functioning in Individuals With Affective Disorders
This study investigates the utility of Goal Management Training (GMT) in patients with post-traumatic stress disorder (PTSD), in order to determine if this treatment is effective in improving cognitive function in patients with…
- Trial name
- NCT04076839
- Testing
- Goal Management Training
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- Homewood Research Institute
Schizophrenia, Schizoaffective Disorder
Integrative Neuro-social Cognitive Strategy Programme for Instilling REcovery (INSPIRE) a Community-Based Cognitive Remediation Trial
Adults with serious mental illnesses (such as schizophrenia and schizoaffective disorders) often experience a range of cognitive difficulties (such as memory, problem solving difficulties) that affect their ability to lead…
- Trial name
- NCT06286202
- Testing
- Cognitive Remediation: Adapted Neuropsychological and Education Approach to Remediation (NEAR), Standard Psychiatric Rehabilitation at Anglican Care Centers
- Where
- 5 sites in Singapore
- Volunteers
- 160 people
- Sponsor
- Singapore Institute of Technology
Schizophrenia, Schizoaffective Disorder
Cognitive Remediation Therapy Within a Secure Forensic Setting
This clinical trial tests the feasibility, effectiveness and patient satisfaction with cognitive remediation therapy for patients diagnosed with schizophrenia or schizoaffective disorder within a forensic hospital.
- Conditions
- Schizophrenia, Schizoaffective Disorder, Cognitive Deficits
- Trial name
- NCT02360813
- Testing
- Cognitive Remediation Therapy, Treatment as usual
- Where
- Ireland
- Volunteers
- 65 people
- Sponsor
- Central Mental Hospital
Schizophrenia Disorders, Cognitive Dysfunction
Cognitive Remediation Therapy for Schizophrenia: Effects on EEG and Emotional Regulation
This study aims to determine whether Cognitive Remediation Therapy (CRT) can improve attention, memory, and emotional regulation in people with schizophrenia.
- Conditions
- Schizophrenia Disorders, Cognitive Dysfunction, Emotion Regulation Disorders
- Trial name
- CRT-SCHZ (NCT06936397)
- Testing
- Cognitive Remediation Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Beykoz University
Schizophrenia
A Study of a Remediation Program of Social Cognition in Schizophrenia
Theory of mind (ability to infer others' intention, emotion, etc) is known to be altered in patients with schizophrenia and its deficit to be correlated with their decreased social proficiency.
- Trial name
- REMEDCOG (NCT01077791)
- Testing
- original cognitive therapy
- Where
- France
- Volunteers
- 26 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Schizophrenia
Efficacy of ISST in Schizophrenia
The ISST study investigates whether integrated social cognitive remediation and social behavioral skills therapy is more efficacious in improving functional outcome and treatment adherence than an active control treatment…
- Trial name
- NCT02678858
- Testing
- Integrated Social Cognitive and Behavioral Skills Therapy, Neurocognitive Remediation Therapy
- Where
- 6 sites in Germany
- Volunteers
- 177 people
- Sponsor
- Heinrich-Heine University, Duesseldorf
Multiple Sclerosis, Cognitive Decline
Computerized Cognitive Training in MS
WHO: 40 participants with a confirmed diagnosis of Multiple Sclerosis (MS) able to engage in moderate physical activity. WHY: The purpose of this study is to evaluate two computerized brain training tools, which include light…
- Trial name
- NCT03737825
- Testing
- Computerized gaming rehabilitation Program 1, Computerized gaming rehabilitation Program 2
- Where
- 2 sites in United States, Switzerland
- Volunteers
- 2 people
- Sponsor
- University of California, San Francisco
Schizophrenia
RC2S+: Remediation of Social Cognitive Impairments
Background: Difficulties in social interactions are a central characteristic of people with schizophrenia, and can be partly explained by impairments of social cognitive processes.
- Trial name
- RC2S+ (NCT02976077)
- Testing
- RC2S+, active comparator
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Hôpital le Vinatier
Post-Acute COVID-19 Syndrome
Brain-Training Treatment for Long COVID in Older Adults
This research is being done to collect preliminary data on the potential of computerized "brain-training" exercises for treating Long COVID symptoms in older adults.
- Trial name
- NCT05705193
- Testing
- NeuroFlex (computerized gamified tasks)
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- UConn Health
Psychiatric Disorders, Depression - Major Depressive Disorder
Implementing Action-Based Cognitive Remediation for Transdiagnostic Cognitive Difficulties in a Tertiary Mental Health Hospital
Psychiatric conditions are each defined by different set of symptoms, however, they often share common characteristics such as impairments in cognitive and social functioning.
- Conditions
- Psychiatric Disorders, Depression - Major Depressive Disorder, Schizophrenia and Other Psychotic Disorders, Anxiety and Mood Disorders
- Trial name
- NCT07506070
- Testing
- Action-Based Cognitive Remediation
- Volunteers
- 160 people
- Sponsor
- The Royal Ottawa Mental Health Centre
Psychosis, Schizophrenia
Contrasting Group Therapy Methods for Psychosis
Current Canadian Clinical Practice guidelines emphasize the need for effective psychosocial adjuncts to pharmacotherapy for schizophrenia (Canadian Psychiatric Association 2005).
- Conditions
- Psychosis, Schizophrenia, Schizoaffective Disorder, Schizophreniform Disorder
- Trial name
- MCT (NCT01764568)
- Testing
- Metacognitive Training (MCT), Cognitive Remediation (CR)
- Where
- Canada
- Volunteers
- 129 people
- Sponsor
- University of British Columbia
Schizophrenia
Seroquel® Combined With Cognitive Remediation Therapy to Conventional Treatment in Patients With Schizophrenia
The purpose of this study is to compare efficacy of quetiapine fumarate combined with Cognitive Remediation Therapy (CRT) to conventional treatment by evaluating change in social outcome in patients with schizophrenia.
- Trial name
- SCORE (NCT00255515)
- Testing
- Quetiapine fumarate, conventional treatment for schizophrenia
- Where
- 15 sites in Sweden
- Volunteers
- 85 people
- Sponsor
- AstraZeneca
Post COVID-19 Condition
Multidisciplinary Day-hospital Versus Waiting List Management of Post-COVID-19 Persistent Symptoms (ECHAP-COVID)
After an acute episode of COVID-19, many patients experience persistent or recurrent symptoms with substantial impairment of their quality of life.
- Trial name
- ECHAP-COVID (NCT05532904)
- Testing
- Personalized multidisciplinary day-hospital intervention
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Anorexia Nervosa
Efficacity of Cognitive Remediation Treatment Compared to a Controlled Group in Young Patient With Anorexia Nervosa
The aim of research is to test in a randomized clinical trial with active sessions, the efficacy of cognitive remediation therapy in children anorexia nervosa compared to a controlled group.
- Trial name
- RECOGAMEA (NCT02400541)
- Testing
- Cognitive remediation therapy, relaxation therapy
- Where
- France
- Volunteers
- 65 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Psychosis
Transcranial Direct Current Stimulation and Cognitive Remediation Therapy for Psychosis
The proposed pilot study is a randomized controlled study to assess effectiveness of transcranial direct current stimulation (tDCS) to enhance cognitive remediation therapy in patients with psychotic disorders. tDCS.
- Trial name
- NCT02085421
- Testing
- tDCS
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- University of Minnesota
Cognitive Dysfunction, Cognition Disorders
Multiple Interventions to Prevent Cognitive Decline
The investigators aim to test the feasibility of a pragmatic non-pharmacological strategy, that may prevent cognitive decline in patients with mild cognitive impairment.
- Conditions
- Cognitive Dysfunction, Cognition Disorders, Memory Disorders
- Trial name
- MIND (NCT04079075)
- Testing
- Cognitive training, Physical activity, Nutrition education
- Where
- Portugal
- Volunteers
- 50 people
- Sponsor
- Universidade do Porto
Schizophrenia
Cognitive Remediation Plus Aerobic Exercise in Schizophrenia Treatment
Cognitive remediation (CR) and aerobic exercise have separately shown promising results in schizophrenia cognitive improvement, despite this, the impact in improving functionality is still limited.
- Trial name
- NCT02864576
- Testing
- Cognitive Remediation_Aerobic Exercise, Cognitive Remediation_Health Promotion
- Where
- Spain
- Volunteers
- 74 people
- Sponsor
- Parc de Salut Mar