Clinical trials: Cognitive Testing
Validation of Online Cognitive Testing
Online Neuropsychological Test Validation Project With Imaging Pilot
This is a five year study conducted in cooperation with the Brain Health Registry (BHR), an internet-based registry which enrolls adult volunteers in order to facilitate clinical trials for the prevention of Alzheimer's disease…
- Trial name
- NVP (NCT02486250)
- Testing
- Validation Study
- Where
- United States
- Volunteers
- 982 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Dual-task, Functional Test
Reference Values of Different Functional Tests With or Without Cognitive Dual-task in Young Adults
In this study, reference values for the five basic functional tests that are commonly used, with and without the addition of dual-task activity, will be determined.
- Trial name
- NCT05373160
- Testing
- Assessment study
- Where
- Turkey (Türkiye)
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- Istanbul Bilgi University
Alzheimer's Disease
Normative Values for Cognitive Testing and Alzheimer's Imaging Biomarkers in Young Adults
Biomarkers of Alzheimer's disease (AD) occupy an essential place in recently formulated diagnostic criteria for AD where their role is to identify the pathophysiological processes underlying cognitive impairment or to predict…
- Trial name
- NCT01609335
- Testing
- F-18 FDG, C-11 PiB
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Cognitive Change
Effect of Alpha Hope Dietary Supplement on Health and Cognitive Performance
The purpose of the present research study is to evaluate the claims about the supplement influencing cognitive function that may impact performance on cognitive task and related biochemical measures.
- Trial name
- NCT05589051
- Testing
- Drink
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Memphis
Alzheimer Disease
Davos Alzheimer's Collaborative Study: Sequential Administration of Digital Testing To Screen For Cognitive Impairment Followed By Blood Based Biomarkers To Assist With Timely Detection And Accurate Diagnosis Of Alzheimer's Disease
The purpose of this study is to investigate how we can detect Alzheimer's disease early by using an online memory test and a simple blood test.
- Trial name
- DAC (NCT05379348)
- Testing
- Cognitive Assessment
- Where
- United States
- Volunteers
- 1,423 people, healthy volunteers welcome
- Sponsor
- AdventHealth Translational Research Institute
Metabolic Syndrome
Optimal Metabolic Health Through Continuous Glucose Monitoring
The primary focus of this study is to evaluate the role of Continuous Glucose Monitoring (CGM) with Levels Health software as a tool to provide feedback and accountability necessary to create sustainable behavioral changes in…
- Trial name
- CGM (NCT04920058)
- Testing
- Continuous Glucose Monitor, <Active Comparator?>
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Attention-Deficit/Hyperactivity Disorder
Role of Circadian and Homeostatic Systems in the Regulation of Wakefulness in Adult Patients With Attention Deficit Disorder With or Without Hyperactivity
In a previous protocol, we highlighted an excessive daytime sleepiness at the Maintenance of Wakefulness Tests (MWT) in 36% of adult Attention Deficit Disorder with or without Hyperactivity (ADHD) patients.
- Trial name
- VEILLETDAH (NCT02217371)
- Testing
- Neuropsychological tests
- Where
- France
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Mild Cognitive Impairment
Neurotrack Test Validation Protocol
This protocol describes a study to validate Neurotrack's visual paired comparison task, aimed at early detection and monitoring of memory impairment.
- Trial name
- NCT02608021
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Frailty, Cognitive Impairment
Orthopedic Procedures and Postoperative Delirium in Older Adults in the Czech Republic
This multicenter, prospective, non-interventional observational study (ORTOPODCZ) investigates the association between preoperative cognitive impairment and postoperative delirium (POD) in older adults undergoing elective total…
- Conditions
- Frailty, Cognitive Impairment, Older Adults, Hip Arthroplasty
- Trial name
- ORTOPODCZ (NCT07432009)
- Where
- 7 sites in Czechia
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Tomas Bata Hospital, Czech Republic
Cardiac Arrest, Cognitive Function
Brain Function After Cardiac Arrest (Measured With FMRI and Cognitive Tests)
The aim of this longitudinal study is to determine whether brain function is affected after a cardiac arrest. The primary question is whether cognitive function is affected after cardiac arrest and whether it changes over time…
- Trial name
- BRAINnHEART (NCT03579498)
- Where
- 2 sites in Norway, Sweden
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Schizophrenia, Memory Disorders
The Effects of Atomoxetine on Cognition and Brain Function Based on Catechol-O-methyltransferase(COMT) Genotype
This study will evaluate whether Atomoxetine improves cognition in healthy volunteers as well as patients with schizophrenia. Atomoxetine is a drug that has been Food and Drug Administration (FDA) approved for Attention Deficit…
- Conditions
- Schizophrenia, Memory Disorders, Cognition Disorders
- Trial name
- Atomoxetine (NCT00548327)
- Testing
- Atomoxetine, Functional magnetic resonance imaging, Neuropsychological Testing
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Glucose Tolerance, Appetite Sensations
Effects of Nopal Fractions on Postprandial Glucose Regulation and Appetite Variables in Healthy Humans
Postprandial effects of Nopal fractions on glucose and appetite regulation will be investigated in healthy humans, in a randomised controlled crossover trial
- Trial name
- NCT04439630
- Testing
- Nopal fractions, Test product without the active components
- Where
- Sweden
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Lund University
HIV
A Cognitive Behavioral Therapy Group Intervention to Increase HIV Testing and PrEP Use Among Latinx Sexual Minority Men
This study consists of a randomized controlled trial (RCT) of a multi-session cognitive behavior therapy (CBT) group intervention that aims to improve HIV outcomes by increasing adaptive, effective coping responses to stigma from…
- Trial name
- NCT04225832
- Testing
- CBT Coping Intervention
- Where
- United States
- Volunteers
- 289 people, healthy volunteers welcome
- Sponsor
- RAND
Schizotypal Personality Disorder, SPD
CRT-Guanfacine for SPD
This is a study to assess the efficacy augmenting cognitive remediation therapy (CRT) with a pharmacological agent for individuals with schizotypal personality disorder (SPD).
- Trial name
- NCT02524899
- Testing
- Cognitive Remediation Therapy, Guanfacine
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Healthy Volunteers
An Online Study of the Reliability of the Brain Performance Test (BPT)
The purpose of this study is to evaluate test-retest reliability of each subtest (correlation coefficients for Time 1 and 2) in the Brain Performance Test (BPT, Lumos Labs, Inc.).
- Trial name
- NCT02403609
- Testing
- BPT, Computerized Assessment
- Where
- United States
- Volunteers
- 1,357 people, healthy volunteers welcome
- Sponsor
- Lumos Labs, Inc.
Cognitive Performance
Effect of Phytochemicals on Aspects of Cognitive Performance
The primary purpose of the research is to test the short-term effects of the consumption of beverages containing phytochemicals and caffeine on several aspects of cognitive performance.
- Trial name
- NCT02167750
- Testing
- Cherry Flavored Beverage
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
eHealth
Dr Solitaire: Assessing Cognitive Performance Through Meaningful Play
To assess cognitive performance by means of the game of Solitaire. In this study, the investigators want to define relevant game metrics, when playing Solitaire, that may be indicative of cognitive performance.
- Trial name
- NCT02971124
- Where
- 2 sites in Belgium
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Sedentary Behavior, Affect
Effects of Multi-day Interruptions in Sitting on Type 2 Diabetes-relevant Outcomes in Children
The overall objective of this in-lab randomized controlled trial is to test the efficacy of multi-day interruptions in sedentary behavior vs.
- Conditions
- Sedentary Behavior, Affect, Metabolic Disturbance, Anxiety
- Trial name
- NCT04469790
- Testing
- SIT+WALK, EX
- Where
- United States
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Neuropsychological Test
Cognitive Function Evaluation and Rehabilitation by a Digital Game: MentalPlus®
Cognitive dysfunction is a frequent adverse event in the postoperative period, especially in elderly patients. The tests commonly used for the detection of postoperative cognitive dysfunction (POCD) are time-consuming, which…
- Trial name
- MentalPlus® (NCT04637191)
- Testing
- MentalPlus®
- Where
- Brazil
- Volunteers
- 163 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Alzheimer Disease, Cognitive Decline
Computerized Tests of Cognitive Decline in Presymptomatic Alzheimer's Disease
The investigators will study performance on computerized cognitive tasks in healthy participants of different ages to gather normative data for newly developed computerized cognitive tests.
- Conditions
- Alzheimer Disease, Cognitive Decline, Aging
- Trial name
- NCT04800588
- Testing
- California Cognitive Assessment Battery
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Neurobehavioral Systems, Inc.