Clinical trials: Cognitive Therapy
Post Traumatic Stress Disorder, Relational Problems
Brief Cognitive Behavioral Conjoint Therapy for PTSD With Adjunctive Intranasal Oxytocin
In 2019 VA mandated that all Veterans seeking mental health care have access to flexible family mental health services in VA (VHA directive 1163.04).
- Trial name
- CBCT+OT (NCT05207436)
- Testing
- Oxytocin nasal spray, Brief Cognitive-Behavioral Conjoint Therapy
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- San Diego Veterans Healthcare System
HIV, Aging
A Novel Neurorehabilitation Approach for Cognitive Aging With HIV
The goal of this study is to conduct a small, self-contained project to test the hypothesis that tDCS will augment SOP cognitive remediation therapy (CRT) in older HIV+ adults.
- Trial name
- HtDCS (NCT02391311)
- Testing
- transcranial direct current stimulation (tDCS)
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- University of Alabama at Birmingham
Traumatic Brain Injury
Effects of LEDs on Memory in TBI Patients
The purpose of the study is to investigate whether transcranial, high-intensity LED placed on the scalp can improve working memory in people who have sustained a concussion with lingering effects or a mild brain injury.
- Trial name
- LED (NCT01598532)
- Testing
- MedX Health Phototherapy (light therapy)
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Spaulding Rehabilitation Hospital
PTSD
A Comparison of Cognitive Processing Therapy (CPT) Versus Present Centered Therapy (PCT) for Veterans
The purpose of this study is to compare the effectiveness of Cognitive Processing Therapy (CPT) versus Present Centered Therapy (PCT) for male OEF/OIF Veterans with combat related PTSD.
- Trial name
- NCT00607815
- Testing
- Cognitive Processing Therapy, Present Centered Therapy
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- VA Office of Research and Development
Post-traumatic Stress Disorder
Increasing Engagement in Evidence-Based PTSD Therapy for Primary Care Veterans
The purpose of this study is to implement an evidence-based Referral Management System that will address patient and system-level barriers to the uptake of evidence-based psychotherapy for PTSD by Veterans Affairs primary care…
- Trial name
- NCT01984515
- Testing
- Referral Management System
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- VA Office of Research and Development
Depression
Cognitive Therapy for Recurrent Depression
This study determined the effectiveness of continuation phase cognitive therapy versus antidepressant medication in preventing relapse of depression in people with recurrent depression.
- Trial name
- NCT00118404
- Testing
- Continuation phase cognitive therapy, Continuation phase fluoxetine, Acute phase cognitive therapy
- Where
- 2 sites in United States
- Volunteers
- 523 people
- Sponsor
- University of Texas Southwestern Medical Center
Prolonged Grief Disorder
Treatment of Prolonged Grief Disorder in Combat Veterans
The purpose of this study is to compare the efficacy of an experimental treatment (termed BATE-G) for Prolonged Grief Disorder (PGD) in Veterans compared to the current, VA-approved standard of care treatment.
- Trial name
- PGD (NCT02283333)
- Testing
- BATE-G, Standard Treatment
- Where
- 2 sites in United States
- Volunteers
- 155 people
- Sponsor
- VA Office of Research and Development
Binge-Eating Disorder, Obesity
Cognitive-Behavioral and Pharmacologic (LDX) Treatment of Binge-Eating Disorder and Obesity: Medication Change for Non-Responders
This study will test the relative efficacy and effectiveness of the combination of naltrexone and bupropion (NB) medication as a treatment for binge-eating disorder (BED) in patients with obesity.
- Trial name
- NCT03946111
- Testing
- Naltrexone and Bupropion
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Yale University
Type 2 Diabetes, Depression
Cognitive Behavioral Therapy for Adherence in Patients With Type 2 Diabetes
Despite the significant relationship between depression and diabetes, there are few published studies testing the effect of cognitive behavioral therapy in improving disease outcomes among diabetics in primary healthcare settings…
- Trial name
- NCT04214600
- Testing
- Cognitive Behavioral Therapy (CBT)
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Cairo University
Intractable Pain
Behavioral Treatments for Chronic Pain
The purpose of the study is to test a brief, group-administered psychosocial intervention to reduce interference of pain with daily life, emotional distress, and pain intensity, and improve quality of life and physical activity…
- Trial name
- NCT00371865
- Testing
- Cognitive-behavioral therapy, Acceptance-based therapy
- Where
- United States
- Volunteers
- 114 people
- Sponsor
- US Department of Veterans Affairs
Attention Deficit Disorder, Attention Deficit Hyperactivity Disorder
Shire SCT: Lisdexamfetamine Treatment for ADHD and SCT
The primary purpose of this study is to test the efficacy of Lisdexamfetamine in Adults With Attention Deficit Hyperactivity Disorder (ADHD) and Sluggish Cognitive Tempo (SCT).
- Trial name
- NCT02635035
- Testing
- Lisdexamfetamine
- Where
- 2 sites in United States
- Volunteers
- 38 people
- Sponsor
- NYU Langone Health
Major Depressive Disorder
Aripiprazole Augmentation of SSRI Therapy in Treatment Refractory Depression
Our target population will have been adequately treated with one of three selective serotonin reuptake inhibitors (SSRIs; escitalopram, citalopram, or sertraline) for at least 8-12 weeks and continue to experience symptoms of…
- Trial name
- NCT00608543
- Testing
- Aripiprazole
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- University of Texas Southwestern Medical Center
Stroke
Robot-Assisted Therapy and Motor Learning: An Active Learning Program for Stroke
Stroke is the leading cause of long-term disability in older adults in the United States. At six months after stroke, up to 65% of the more than 795,000 persons who experience a stroke each year continue to have motor impairments…
- Trial name
- ALPS (NCT02747433)
- Testing
- Robot-Assisted Therapy (RT), Robot & Task-Oriented Training (RT-TOT)
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Spaulding Rehabilitation Hospital
Low Back Pain, Chronic Pain
Optimize Low Back Pain
The objective of this study is to improve health care for patients with chronic LBP and increase the likelihood that patients obtain outcomes that matter most to them.
- Trial name
- OPTIMIZE (NCT03859713)
- Testing
- Physical Therapy, Cognitive Behavioral Therapy, Mindfulness
- Where
- 3 sites in United States
- Volunteers
- 749 people
- Sponsor
- University of Utah
Autism Spectrum Disorder
Oxytocin and Social Cognitive Skills Groups
The purpose of this study is to evaluate the feasibility, safety, and preliminary efficacy of integrating targeted dosing of intranasal oxytocin with a social cognitive skills group therapy for school-aged children with autism…
- Trial name
- ION-ASD (NCT02918864)
- Testing
- Oxytocin, Social Cognitive Skills Training, Facilitated Play Therapy
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Rush University Medical Center
Insomnia, Depression
A Novel Use of a Sleep Intervention to Target the Emotion Regulation Brain Network to Treat Depression and Anxiety
Several lines of evidence suggest that unhealthy sleep patterns contribute to depressive symptoms through disruption of brain networks that regulate emotional functions.
- Trial name
- NCT04424407
- Testing
- Cognitive Behavioral Therapy for Insomnia
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Stanford University
Autism, Asperger's Syndrome
Cognitive-Behavioral Treatment for Anxiety Disorders in Children With Autism Spectrum Disorders
Autism spectrum disorders affect as many as 1 out of 150 children and are related to significant impairment in social, adaptive, and school functioning.
- Conditions
- Autism, Asperger's Syndrome, Generalized Anxiety Disorder, Social Phobia
- Trial name
- NCT01178385
- Testing
- Cognitive-behavioral therapy, Treatment as Usual
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Depression
Identifying Factors That Predict Antidepressant Treatment Response
This study will compare different treatments for depression in order to identify which factors predict effectiveness, and will include a companion study which investigates combining treatments and long term effectiveness.
- Trial name
- NCT00360399
- Testing
- Escitalopram, Duloxetine, Cognitive behavioral therapy (CBT)
- Where
- 2 sites in United States
- Volunteers
- 344 people
- Sponsor
- Emory University
HIV
A Cognitive Behavioral Therapy Group Intervention to Increase HIV Testing and PrEP Use Among Latinx Sexual Minority Men
This study consists of a randomized controlled trial (RCT) of a multi-session cognitive behavior therapy (CBT) group intervention that aims to improve HIV outcomes by increasing adaptive, effective coping responses to stigma from…
- Trial name
- NCT04225832
- Testing
- CBT Coping Intervention
- Where
- United States
- Volunteers
- 289 people, healthy volunteers welcome
- Sponsor
- RAND
Bullying, Weight, Body
Cognitive-Behavioral Therapy for Weight-related Bullying (Online Treatment)
This study will perform a clinical trial with adolescents to pilot a new cognitive-behavioral treatment (CBT) for weight-related bullying testing (1) feasibility, (2) acceptability, and (3) initial efficacy.
- Conditions
- Bullying, Weight, Body, Trauma, Psychological
- Trial name
- NCT04587752
- Testing
- CBT for Weight Bullying
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Yale University