Clinical trials: Cognitive Wellness
Cancer Survivor, Insomnia
Yoga, Survivorship Health Education, and Cognitive Behavioral Therapy in Reducing Insomnia in Cancer Survivors
This randomized phase III trial compares yoga, survivorship health education program, and cognitive behavioral therapy in reducing sleep disturbance (insomnia) in cancer survivors.
- Conditions
- Cancer Survivor, Insomnia, Malignant Neoplasm
- Trial name
- YOCAS-II (NCT02613364)
- Testing
- Behavioral Intervention, Cognitive Intervention, Educational Intervention
- Where
- 16 sites in United States
- Volunteers
- 746 people
- Sponsor
- University of Rochester NCORP Research Base
Type 2 Diabetes, Depression
Cognitive Behavioral Therapy for Adherence in Patients With Type 2 Diabetes
Despite the significant relationship between depression and diabetes, there are few published studies testing the effect of cognitive behavioral therapy in improving disease outcomes among diabetics in primary healthcare settings…
- Trial name
- NCT04214600
- Testing
- Cognitive Behavioral Therapy (CBT)
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Cairo University
Aging, Mild Cognitive Impairment
Internet-based Conversational Engagement Clinical Trial
The study aims to randomize 320 (160 Caucasian, 160 African American) socially isolated adults 75+ years old (50:50 split between those with normal cognition and mild cognitive impairment (MCI)) recruited from the community to…
- Trial name
- I-CONECT (NCT02871921)
- Testing
- Conversational Engagement
- Where
- 2 sites in United States
- Volunteers
- 186 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Mild Cognitive Impairment
A Scalable Model for Promoting Functioning and Well-Being Among Older Adults With Mild Cognitive Impairment Via Meaningful Social Interactions: Project SPEAK!
The goal of this study is to refine and test a strategy for engaging older adults with symptoms of SCD/MCI (subjective cognitive decline/mild cognitive impairment) as volunteers to help English language learners (ELLs) who live…
- Trial name
- NCT04717479
- Testing
- Intervention (videoconferencing)
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Smoking Cessation
Interventions of Smoking Cessation During Pregnancy
The aim of this clinical trial is to test whether offering pregnant smokers a high intensity intervention for smoking cessation increases the rate of smoking cessation at the third trimester of pregnancy, compared to low…
- Trial name
- NCT01210118
- Testing
- Low intensity intervention, Higher intensity intervention
- Where
- 2 sites in Greece
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Hellenic Anticancer Society
Suicide, Psychosis
Cognitive Behavioral Suicide Prevention for Psychosis: Aim 2
Investigators will evaluate the feasibility and preliminary effectiveness of modified Cognitive Behavioral Suicide Prevention for psychosis (CBSPp) in comparison to services-as-usual (SAU) in a randomized controlled trial.
- Trial name
- NCT05345184
- Testing
- Cognitive Behavioral Suicide Prevention for psychosis (CBSPp), Services as Usual (SAU)
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- University of Michigan
Elder Abuse, Elder Mistreatment
Feasibility of Elder Mistreatment VOICES-CI Screening Tool
The aim of this study is to assess the feasibility of the VOICES Elder Abuse Intervention among older adults with cognitive impairment.
- Trial name
- VOICES-CI (NCT05216081)
- Testing
- Virtual cOaching in making Informed Choices on Elder Mistreatment Self-Disclosure (VOICES)
- Where
- United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Yale University
Smoking Cessation
CoQuit Study for Smoking Cessation
This study investigated the feasibility of a cognitive dissonance-based mobile app for smoking cessation (CDI). Cognitive dissonance refers to the conflict between beliefs and behaviors; interventions are designed to promote this…
- Trial name
- NCT04893460
- Testing
- CoQuit App
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Oregon Research Behavioral Intervention Strategies, Inc.
Depression
Improving Depression Management
Depression is disabling and affects one in five Veterans. VA's Primary Care-Mental health Integration (PC-MHI) enables specialists to support medication treatment in primary care, but timely and sufficient access to psychotherapy…
- Trial name
- IDMPC (NCT05050227)
- Testing
- cCBT Enhanced Collaborative Care, Usual Care
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- VA Office of Research and Development
Smoking Cessation, Schizophrenia
Effectiveness of Tropisetron Plus Risperidone for Improving Cognitive and Perceptual Disturbances in Schizophrenia
This study will determine the effectiveness of tropisetron plus risperidone in improving cognitive symptoms in Chinese people with schizophrenia.
- Trial name
- NCT00435370
- Testing
- Tropisetron, Risperidone
- Where
- 2 sites in United States, China
- Volunteers
- 179 people
- Sponsor
- Baylor College of Medicine
Smoking Cessation
Cognitive Remediation With D-Cycloserine
One hundred seventy-five eligible participants will be enrolled with aim of randomizing 60 to a double-blind, placebo-controlled trial of D-cycloserine added to cue-exposure treatment to prevent relapse to smoking.
- Trial name
- NCT01399866
- Testing
- D-cycloserine
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Depression Anxiety and Co-occurring Rural Youth
Implementing and Evaluating an Internet-based Cognitive Behavior Therapy Intervention in School Settings
This research study examines rural youth's experience of an internet based cognitive behavioral therapy intervention, and their experience of symptoms of depression, anxiety and co-occurring disorders.
- Trial name
- NCT04928001
- Testing
- internet based iCBT program, Youth Thrive
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Montana State University
Cognitive Impairment, Frail Elderly Syndrome
Preoperative Cognitive Screening in Older Spinal Surgical Patients
The objectives of this study are to determine whether identifying patients with baseline cognitive deficits or frailty predict postoperative delirium.
- Trial name
- NCT02922634
- Testing
- Mini Cog
- Where
- United States
- Volunteers
- 229 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Cognitive Decline, Social Isolation
Evaluation of the Wits Workout Wellness Program for Older Adults
About 11% of the U.S. older adult population is at risk for or suffers from subjective cognitive decline. While some factors such as genetics and habitual physiological changes that affect brain health cannot be changed, research…
- Conditions
- Cognitive Decline, Social Isolation, Health Behaviors, Self Efficacy
- Trial name
- NCT04928885
- Testing
- Wits Workout Program, Control Group that receives intervention after the study
- Where
- United States
- Volunteers
- 285 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Tobacco Dependence
Tobacco Dependence Treatment for Asian Americans
Nicotine dependence is very common among Asian Americans; yet, research on understanding and treating nicotine dependence in this group is almost nonexistent.
- Trial name
- NCT01091363
- Testing
- Standard, Deep Cultural
- Where
- United States
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Boston
Smoking Cessation
Cognition and Smoking Relapse (HCS)
This study tests whether withdrawal-related cognitive deficits increase smoking relapse among HIV-infected (HIV+) vs. HIV-uninfected smokers (HIV-).
- Trial name
- HCS (NCT03169101)
- Testing
- Nicotine patch, Behavioral counseling
- Where
- United States
- Volunteers
- 274 people
- Sponsor
- University of Pennsylvania
Chronic Pain, Pain
Literacy-Adapted Psychosocial Treatments for Chronic Pain --- "Learning About Mastering/My Pain"
Chronic pain is a significant public health problem that affects over 116 million Americans, costs $600 billion annually, and is unequally borne by people in low-income brackets, especially ethnic minorities.
- Conditions
- Chronic Pain, Pain, Widespread Chronic Pain, Chronic Pain Syndrome
- Trial name
- LAMP (NCT01967342)
- Testing
- Pain Ed, CBT for Pain, Usual Care
- Where
- 3 sites in United States
- Volunteers
- 290 people
- Sponsor
- University of Alabama, Tuscaloosa
Insomnia
Digital Cognitive-Behavioral Therapy for Insomnia in Spanish Speaking Latinas/os (Dormir Mejor Study)
The primary objective of the proposed study is to examine the effectiveness of a culturally adapted digital program of cognitive behavioral therapy for insomnia (CBT-I) compared to minimally enhanced usual care (mEUC) on primary…
- Trial name
- NCT05353296
- Testing
- Digital cognitive behavioral therapy for insomnia (CBT-I) program, Minimally Enhanced Usual Care (mEUC), Somryst (culturally adapted)
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Columbia University
Breast Cancer, Gynecologic Cancer
Evaluating Smoking Cessation Protocols in Cancer Patients: NRT, MI, CBT or Hypnotherapy
This trial offers support and assistance to patients wishing to quit smoking in order to increase the success rate of smoking cessation and all the benefits associated with it.
- Conditions
- Breast Cancer, Gynecologic Cancer, Digestive Cancer, Melanoma
- Trial name
- RESPIRE (NCT04899492)
- Testing
- Motivational Interviewing (MI), Cognitive Behavioural Therapy (CBT), Hypnotherapy
- Where
- France
- Volunteers
- 21 people
- Sponsor
- Institut Cancerologie de l'Ouest
Healthy People Programs
Maintaining Cognitive Health in Aging Veterans
Interventions aimed at disseminating information about cognitive aging and lifestyle factors that contribute to successful cognitive aging, in addition to providing broad cognitive skills training, may improve the psychological…
- Trial name
- NCT02023944
- Testing
- Memory and Aging Course
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development