Clinical trials: Cognitive-Behavior Treatment
Depression, Anxiety
Effects of CBT-Based Intervention Among Patients With Liver Cancer
This study investigates the effects of a CBT- based intervention on depression, anxiety, immune function, quality of life, and overall survival.
- Conditions
- Depression, Anxiety, Liver Cancer, CBT
- Trial name
- NCT05942560
- Testing
- Cognitive behavioural therapy-based intervention, Educational group
- Where
- China
- Volunteers
- 160 people
- Sponsor
- The Nethersole School of Nursing
Health Anxiety, Hypochondriasis
Effectiveness of ICBT for Severe Health Anxiety in Clinical Psychiatry.
The aim of this study is to evaluate the clinical effectiveness of internet-based cognitive therapy for severe health anxiety within regular psychiatric care.
- Conditions
- Health Anxiety, Hypochondriasis, Illness Anxiety Disorder, Somatic Symptom Disorder
- Trial name
- NCT04921280
- Testing
- Internet based Cognitive Behavioural Therapy
- Where
- Sweden
- Volunteers
- 456 people
- Sponsor
- Karolinska Institutet
Posttraumatic Stress Disorder, Major Depressive Disorder
TF-CBT for Long-term PTSD, Major Depressive Disorder and Anxiety Disorders in Victims of Terrorism
The objective of this study is to test the efficacy of a Trauma-Focused Cognitive-Behavioural Therapy (TF-CBT) adapted for use with victims of terrorism in Spain who are diagnosed with posttraumatic stress disorder (PTSD), major…
- Conditions
- Posttraumatic Stress Disorder, Major Depressive Disorder, Anxiety Disorders
- Trial name
- NCT05516368
- Testing
- TF-CBT
- Volunteers
- 120 people
- Sponsor
- Universidad Complutense de Madrid
Anxiety, Pregnancy Related
MoodUP in Improving Psychological Outcomes Among Perinatal Women
Dramatic physiological, psychological, and social changes during the antenatal period may significantly affect a woman's psychosocial and physical conditions, thereby resulting in stress, anxiety, and depressive symptoms.
- Conditions
- Anxiety, Pregnancy Related, Perinatal Depression, Prenatal Stress
- Trial name
- NCT03970057
- Testing
- Internet-based Cognitive Behavioural Therapy, Usual Care
- Where
- Singapore
- Volunteers
- 368 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Stress Disorders, Post-Traumatic, Substance-Related Disorders
Cognitive Behavioral Therapy (CBT) for Posttraumatic Stress Disorder (PTSD) in Community Addiction Treatment
The purpose of this phase of the study is to assess the efficacy of CBT for PTSD, as delivered by routine addiction counselors in community treatment programs, and to compare CBT for PTSD with both Individual Addiction Counseling…
- Trial name
- NCT01457391
- Testing
- Cognitive Behavioral Therapy, Individual Addiction Counseling, Treatment-as-usual
- Where
- 4 sites in United States
- Volunteers
- 443 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Generalized Anxiety Disorder, Panic Disorder
Neural Functioning Underlying Anxiety and Its Treatment (The INSULA Study)
This study will examine the effects of cognitive behavioral therapy on brain function in people with anxiety disorders.
- Conditions
- Generalized Anxiety Disorder, Panic Disorder, Anxiety Disorders
- Trial name
- NCT00947570
- Testing
- Cognitive behavioral therapy for anxiety
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Alzheimer Disease
Memantine Treatment in Alzheimer's Disease Patients
The aim of this study is to investigate whether there will be any efficacy difference of Memantine treatment in different cognitive severity AD patients stratified with BPSD
- Trial name
- NCT03168997
- Testing
- Memantine Hydrochloride
- Volunteers
- 222 people
- Sponsor
- Wei Cuibai
Obsessive-Compulsive Disorder, Generalized Anxiety Disorder
Improving Attentional and Cognitive Control in the Psychological Treatment of Intrusive Thoughts
The investigators are conducting this study to learn more about the cognitive and attentional processes among individuals with three types of repetitive negative thinking (RNT): mental rituals (as seen in obsessive compulsive…
- Conditions
- Obsessive-Compulsive Disorder, Generalized Anxiety Disorder, Major Depressive Disorder
- Trial name
- NCT04225624
- Testing
- Emotion Regulation Therapy - Attention Regulation (AR-ERT), Supportive Psychotherapy (SPT)
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Massachusetts General Hospital
Cancer Survivors, Anxiety
Pilot Study of Internet-Delivered Psychological Treatment for Cancer Survivors
Negative psychological effects of cancer are common, but cancer survivors are rarely offered structured psychological treatment.
- Conditions
- Cancer Survivors, Anxiety, Depression
- Trial name
- IN-FACT-0 (NCT06046573)
- Testing
- Support and information, Behavioral activation, Systematic exposure with mindfulness training
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Karolinska Institutet
PTSD
Effects of Mindfulness-Based Cognitive-Behavioral Conjoint Therapy on PTSD and Relationship Function
The purpose of this study is to first adapt Cognitive Behavioral Conjoint Therapy for PTSD for Operation Enduring Freedom and Operation Iraqi Freedom (OEF-OIF) Veterans diagnosed with PTSD and their intimate partners by (1)…
- Trial name
- NCT01035788
- Testing
- Mindfulness Based Cognitive Behavioral Conjoint Therapy, CBCT for PTSD - Communication Skills
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- VA Office of Research and Development
Gambling Disorder
Internet-CBT for Gambling Disorder - a Randomized Controlled Trial
The study is a randomized controlled trial (Total N=150; each condition n=75) of internet-based cognitive behavioral therapy (iCBT), with measures at pre, weekly during treatment, post, three and at six month follow-up.
- Trial name
- NCT06099522
- Testing
- Internet-based cognitive behavioral therapy (iCBT)
- Where
- Sweden
- Volunteers
- 150 people
- Sponsor
- Karolinska Institutet
Depression
Augmenting Internet-Based Cognitive Behavioral Therapy for Major Depressive Disorder With Low-Level Light Therapy
The purpose of this study is to better understand how low-level light therapy (LLLT) can be used to augment the antidepressant effects of Deprexis, an internet-based treatment program for depression, for participants with current…
- Trial name
- CBT/LLLT (NCT02898233)
- Testing
- Deprexis, Active low-level light therapy
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Texas at Austin
Alcohol Use Disorder, Social Anxiety Disorder
Treatment for Comorbid Social Anxiety and Alcohol Use Disorders.
Alcohol use disorders (AUD) and social anxiety disorder (SAD) are highly comorbid and associated with significant impairment. Social anxiety comorbidity is associated with poorer addiction treatment engagement and outcomes.
- Trial name
- FIT (NCT03428490)
- Testing
- Fully integrated treatment, Stand-alone Intensive Outpatient Program
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- University of California, Los Angeles
Body Dysmorphic Disorder, Somatoform Disorders
Treatment Study Investigating New Cognitive Behavioral Therapy Treatment Manual for Body Dysmorphic Disorder
In an earlier phase of this study, a cognitive behavioral therapy (CBT) manual to treat body dysmorphic disorder (BDD) symptoms was developed.
- Trial name
- NCT00106223
- Testing
- Cognitive behavioral therapy (CBT)
- Where
- 2 sites in United States
- Volunteers
- 36 people
- Sponsor
- Massachusetts General Hospital
Depression
Cognitive Behavioral Therapy by Humor Based Psychoeducation
This study aims to reveal the effectiveness of based cognitive behavioral therapy by humor based psychoeducation on sense of humour, self-esteem and depressıon level patient in diagnosed with deppression .
- Trial name
- NCT06234696
- Testing
- entrepreneurial intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Gaziantep
Childhood Cancer, Cancer-related Problem/Condition
Effect of Cognitively Challenging Physical Activity on Executive Functions in Pediatric Cancer Patients
When it comes to exercise and sport for children and adolescents with cancer, there is often still the opinion that physical activity has a negative effect on the weakened body suffering from cancer.
- Conditions
- Childhood Cancer, Cancer-related Problem/Condition, Cognitive Side Effects of Cancer Therapy, Physical Activity
- Trial name
- KiKli Fit (NCT06839794)
- Testing
- Cognitively challenging physical activity for paediatric cancer patients, Physical activity recommendations
- Where
- Switzerland
- Volunteers
- 70 people
- Sponsor
- University of Bern
Mental Disorders, Mood Disorders
Group Transdiagnostic Cognitive Behavioural Therapy for Intolerance of Uncertainty Versus Applied Relaxation
Many people find uncertainty distressing, but for some, it may become overwhelming and drive persistent anxiety, worry, and avoidance.
- Conditions
- Mental Disorders, Mood Disorders, Anxiety Disorders, Generalized Anxiety Disorder
- Trial name
- OBSCURA (NCT07866794)
- Testing
- Group Transdiagnostic Cognitive Behavioural Therapy for Intolerance of Uncertainty (CBT-IU), Group Transdiagnostic Applied Relaxation (AR)
- Where
- United Kingdom
- Volunteers
- 135 people
- Sponsor
- Medical Research Council Cognition and Brain Sciences Unit
Childhood Traumatic Grief, Post Traumatic Stress
Randomized Controlled Trial of Trauma-focused CBT in Tanzania and Kenya
The primary goal is to study the effectiveness of Trauma-focused Cognitive Behavioral Therapy (TF-CBT) in treating traumatic grief and traumatic stress for orphaned children and young adolescents in two East African sites with…
- Conditions
- Childhood Traumatic Grief, Post Traumatic Stress, Post Traumatic Stress Disorder, Depressive Symptoms
- Trial name
- NCT01822366
- Testing
- Trauma-focused Cognitive Behavioral Therapy
- Where
- 3 sites in United States, Kenya and 1 more
- Volunteers
- 1,280 people
- Sponsor
- Duke University
Posttraumatic Stress Disorder, PTSD
D-cycloserine Adjunctive Treatment for Posttraumatic Stress Disorder (PTSD) in Adolescents
The purpose of this study is to show whether D-cycloserine in combination with cognitive behavioral therapy (CBT) is more effective than CBT plus placebo to reduce symptoms of posttraumatic stress disorder (PTSD) in 13-18…
- Trial name
- NCT01157429
- Testing
- D-cycloserine, CBT
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Tulane University School of Medicine
Migraine
Trans-diagnostic Cognitive-behavioral Therapy for Treatment of Migraine
Migraine headache is one of the disabling conditions that may be associated with decreased quality of life, anxiety and depression.
- Trial name
- NCT03701477
- Testing
- Trans-diagnostic cognitive-behavioral therapy, General relaxation/stress management therapeutic session
- Where
- Iran
- Volunteers
- 20 people
- Sponsor
- Isfahan University of Medical Sciences
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