Clinical trials: Cognitive-Behavior Treatment
Musculoskeletal Pain, Chronic Pain
Living in Full Even With Pain Study
This project will increase our understanding of the mechanisms underlying changes in opioid medication use associated with three psychosocial chronic pain (CP) treatments.
- Trial name
- LIFE (NCT03916276)
- Testing
- Cognitive Therapy (CT), Mindfulness Meditation (MM), Behavioral Activation (BA)
- Where
- United States
- Volunteers
- 91 people
- Sponsor
- University of Washington
Major Depressive Disorder, Recurrent, in Remission, Depressive Symptoms
Reducing Residual Depressive Symptoms With Web-based Mindful Mood Balance
Many patients report residual depressive symptoms despite seemingly successful treatment. With the investigators' previous funding, we developed - Mindful Mood Balance - an online treatment that targets RDS by teaching specific…
- Trial name
- NCT02190968
- Testing
- Usual Depression Care, Mindful Mood Balance
- Where
- United States
- Volunteers
- 460 people
- Sponsor
- University of Toronto
Alcohol Abuse, Alcohol Addiction
Internet-Based Relapse Prevention vs Face to Face Therapy at an Employee Assistance Program
Objectives: This study will evaluate the efficacy of internet-based relapse prevention with therapist support, as compared to face-to-face therapy at an employee assistance program.
- Trial name
- FoBeMA (NCT02014779)
- Testing
- eChange, Face-to-face therapy
- Where
- Sweden
- Volunteers
- 1 people
- Sponsor
- Karolinska Institutet
Obstructive Sleep Apnea, PTSD
Cognitive Behavioral Therapy to Increase CPAP Adherence in Veterans With PTSD
Approximately 20 million Americans suffer from Obstructive Sleep Apnea (OSA) creating risks for major health problems, including dementia, heart attack, and stroke.
- Conditions
- Obstructive Sleep Apnea, PTSD, Posttraumatic Stress Disorder
- Trial name
- NCT02641496
- Testing
- CBT-OSA, Sleep Education
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Autism, Asperger's Syndrome
Cognitive Behavioral Therapy for Anxiety Disorders in Adolescents With Autism
Due to the considerable prevalence of anxiety in youth with autism spectrum disorders, this study seeks to establish the efficacy of a modified cognitive behavioral therapy protocol in 50 adolescents versus other available…
- Conditions
- Autism, Asperger's Syndrome, Pervasive Developmental Disorder Not Otherwise Specified, Generalized Anxiety Disorder
- Trial name
- NCT01563003
- Testing
- Cognitive Behavioral Therapy, Treatment as usual
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Social Anxiety
Online Program for Social Anxiety
The purpose of this study is to investigate the efficacy of an online program in reducing symptoms of social anxiety, unhelpful thoughts, avoidance behaviours, fear of negative evaluations and improving quality of life in…
- Trial name
- NCT02792127
- Testing
- Online Program for Social Anxiety
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Multiple Sclerosis
Cognitive Behavioral Therapy, Modafinil, or Both for Multiple Sclerosis Fatigue
This clinical trial will compare the effectiveness of 3 treatments for fatigue in Multiple Sclerosis: 1) a commonly used behavioral treatment strategy (telephone-based cognitive behavioral therapy), 2) a commonly used medication…
- Trial name
- COMBO-MS (NCT03621761)
- Testing
- Telephone-based Cognitive Behavioral Therapy, Modafinil
- Where
- 2 sites in United States
- Volunteers
- 343 people
- Sponsor
- University of Michigan
Obsessive-Compulsive Disorder
Mindfulness-Based Interventions for OCD
Obsessive-compulsive disorder (OCD) is a severe and debilitating anxiety disorder afflicting about 2% of the population. It is characterized by the presence of recurrent obsessions and/or compulsions that are time consuming and…
- Trial name
- MindOC (NCT04914923)
- Testing
- Muse, Cognitive Behaviour Therapy (CBT), Mindfulness-Based Cognitive Therapy (MBCT)
- Where
- 2 sites in Canada
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Depression, Insomnia
Cognitive Behavioral Therapy for Insomnia with RTMS
Depression and insomnia occur together in a substantial number of patients. Transcranial magnetic stimulation (TMS) is an effective treatment for depression, but does not help insomnia symptoms in depressed patients.
- Trial name
- NCT04258618
- Testing
- CBT-I (Cognitive Behavioral Therapy for Insomnia) with rTMS, Repetitive Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Medical University of South Carolina
Suicide, Attempted, Suicidal Ideation Active
Post Admission Cognitive Therapy (PACT) for the Inpatient Treatment of Military Personnel With Suicidal Behaviors
This study will implement and empirically evaluate the efficacy of a cognitive behavioral intervention program, titled, Post Admission Cognitive Therapy(PACT), for military service members and beneficiaries [with Veterans…
- Trial name
- NCT01359761
- Testing
- Post Admission Cognitive Therapy (PACT)
- Where
- 4 sites in United States
- Volunteers
- 218 people
- Sponsor
- Henry M. Jackson Foundation for the Advancement of Military Medicine
Insomnia, Depression
E-aid Sleep-focused TrEatment for Prevention of Major Depression (STEP-MD)
In the past, there were studies on relationship between insomnia and depression, and those studies found that depression can be the result of untreated insomnia.
- Conditions
- Insomnia, Depression, Self Harm
- Trial name
- NCT03309527
- Testing
- e-aid Cognitive Behavior Therapy, e-aid Sleep Hygiene Education
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Child Psychiatry, Adolescent
Cognitive and Behavioral Therapy in School Refusal
Anxious school refusal (ASR) is a common disorder which concerns more and more adolescents who are at worse completely absent from school.
- Conditions
- Child Psychiatry, Adolescent, Anxious School Refusal, Cognitive Behavioral Therapy
- Trial name
- RSA-Coll (NCT04559633)
- Testing
- cognitive and behavioral therapy (CBT)
- Where
- France
- Volunteers
- 66 people
- Sponsor
- University Hospital, Montpellier
Erectile Dysfunction
Vardenafil and Cognitive-behavioral Sex Therapy for the Treatment of Erectile Dysfunction (STEDOV)
The aim of the present study is to evaluate the efficacy of a combined approach with Vardenafil orodispersible and Cognitive Behavioural Sex Therapy in the treatment of Erectile Dysfunction, compared to medical only treatment, in…
- Trial name
- STEDOV (NCT02450188)
- Testing
- Vardenafil, CBST
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- University of Florence
Sleep Problem, Anxiety Disorders
Better Sleep in Psychiatric Care - Depression, Anxiety and PTSD
Cognitive Behavioral Therapy (CBT) is treatment of choice for insomnia. Many patients in psychiatric care have sleep problems including insomnia, but are rarely given the choice to participate in CBT to improve their sleep.
- Conditions
- Sleep Problem, Anxiety Disorders, Affective Disorder
- Trial name
- BSIP-DAP (NCT04136054)
- Testing
- Adjusted group CBT-i for Depression, Anxiety and PTSD, Care as usual wait-list control group
- Where
- Sweden
- Volunteers
- 131 people
- Sponsor
- Karolinska Institutet
Insomnia, Depression
A Novel Use of a Sleep Intervention to Target the Emotion Regulation Brain Network to Treat Depression and Anxiety
Several lines of evidence suggest that unhealthy sleep patterns contribute to depressive symptoms through disruption of brain networks that regulate emotional functions.
- Trial name
- NCT04424407
- Testing
- Cognitive Behavioral Therapy for Insomnia
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Stanford University
Major Depressive Disorder
Quantitative Electroencephalogram (QEEG) Predictors of Response to Psychotherapy Versus Antidepressant Treatment in Depression
The purpose of this research study is to find out if a test can predict whether someone with depression will get better with treatment.
- Trial name
- NCT00824044
- Testing
- Cognitive Behavioral Therapy (CBT), Escitalopram
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Massachusetts General Hospital
Autism Spectrum Disorder, Sleep Disturbance
Internet-delivered Cognitive Behaviour Therapy for Sleep Problems in ASD
This trial investigates the behavioural effects of Internet-based Cognitive behaviour therapy for insomnia (CBT-I) in adolescents with autism spectrum disorder with sleep problems. This is a randomised controlled trial.
- Conditions
- Autism Spectrum Disorder, Sleep Disturbance, Insomnia
- Trial name
- NCT03624400
- Testing
- Internet-based CBT-I, Internet-based psychoeducation
- Where
- Sweden
- Volunteers
- 240 people
- Sponsor
- Stockholm University
Chronic Pain, Multiple Sclerosis
Telephone Intervention for Pain Study (TIPS)
Treatments teaching people how to manage pain have been used to treat chronic pain in the general population. The purpose of this study is to see if these treatments delivered over the telephone can benefit persons with multiple…
- Conditions
- Chronic Pain, Multiple Sclerosis, Amputation, Spinal Cord Injury
- Trial name
- TIPS (NCT00663663)
- Testing
- Telephone-Delivered Intervention 1, Telephone-Delivered Intervention 2
- Where
- United States
- Volunteers
- 207 people
- Sponsor
- University of Washington
Spinal Cord Injury (SCI)
Interdisciplinary Value-based Cognitive Behavioral Treatment for People With Traumatic Spinal Cord Injury
The goal of this clinical trial is to address the critical need for effective interventions by developing and testing an interdisciplinary values-based cognitive behavioral therapy (V-CBT) program for individuals with spinal cord…
- Trial name
- VALIANT (NCT06599632)
- Testing
- Values-based Cognitive Behavioral Therapy (V-CBT)
- Where
- Denmark
- Volunteers
- 6 people
- Sponsor
- University of Southern Denmark
Brain and Central Nervous System Tumors, Cognitive/Functional Effects
Methylphenidate to Improve Quality of Life in Patients Undergoing Radiation Therapy for Brain Tumors
RATIONALE: Methylphenidate may decrease side effects of radiation therapy. It is not yet known if methylphenidate is effective in improving quality of life in patients with primary or metastatic brain tumors.
- Conditions
- Brain and Central Nervous System Tumors, Cognitive/Functional Effects, Depression, Fatigue
- Trial name
- NCT00031798
- Testing
- methylphenidate hydrochloride, quality-of-life assessment, radiation therapy
- Where
- 7 sites in United States
- Sponsor
- Wake Forest University Health Sciences
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